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https://www.readbyqxmd.com/read/28086775/rapid-decline-in-the-susceptibility-of-plasmodium-falciparum-to-dihydroartemisinin-piperaquine-in-the-south-of-vietnam
#1
Ngo Viet Thanh, Nguyen Thuy-Nhien, Nguyen Thi Kim Tuyen, Nguyen Thanh Tong, Nguyen Thuy Nha-Ca, Le Thanh Dong, Huynh Hong Quang, Jeremy Farrar, Guy Thwaites, Nicholas J White, Marcel Wolbers, Tran Tinh Hien
BACKGROUND: Artemisinin resistant Plasmodium falciparum has emerged in the countries of the Greater Mekong sub-region posing a serious threat to global malaria elimination efforts. The relationship of artemisinin resistance to treatment failure has been unclear. METHODS: In annual studies conducted in three malaria endemic provinces in the south of Vietnam (Binh Phuoc, Ninh Thuan and Gia Lai) between 2011 and 2015, 489 patients with uncomplicated P. falciparum malaria were enrolled in detailed clinical, parasitological and molecular therapeutic response assessments with 42 days follow up...
January 13, 2017: Malaria Journal
https://www.readbyqxmd.com/read/28080899/health-and-nutritional-assessment-of-free-ranging-eastern-indigo-snakes-drymarchon-couperi-in-georgia-united-states
#2
S Emmanuelle Knafo, Terry M Norton, Mark Mitchell, Dirk J Stevenson, Natalie Hyslop, Robert Poppenga, Marcie Oliva, Tai Chen, Carolyn Cray, Samantha E J Gibbs, Lance Durden, Nancy Stedman, Stephen Divers, Ellen Dierenfeld
Clinical pathology and nutritional parameters are useful in evaluating and monitoring threatened and endangered wildlife populations, but reference ranges for most snake species are lacking. From 2001 to 2005, health assessments were performed on 58 eastern indigo snakes (EIS) (Drymarchon couperi) captured in the wild in southeastern Georgia, United States. Health and nutritional assessments performed included hematology, serum biochemistry, fat-soluble vitamins, heavy metals, pesticide contaminants, parasitology, and surveys of other pathogens...
December 2016: Journal of Zoo and Wildlife Medicine: Official Publication of the American Association of Zoo Veterinarians
https://www.readbyqxmd.com/read/28077149/plasmodium-falciparum-malaria-co-infection-with-tick-borne-relapsing-fever-in-dakar
#3
Mamadou A Diallo, Baidy S Kane, Mouhamadou Ndiaye, Mouhamed Dieng, Khadim Diongue, Aida S Badiane, Mame Cheikh Seck, Daouda Ndiaye
BACKGROUND: West African tick-borne relapsing fever (TBRF) due to Borrelia crocidurae and malaria are co-endemics in Senegal. Although expected to be high, co-infections are rarely reported. A case of falciparum malaria and B. crocidurae co-infection in a patient from Velingara (South of Senegal) is discussed. CASE: A 28 year-old-male patient presented to Aristide Le Dantec Hospital for recurrent fever. He initially presented to a local post health of Pikine (sub-urban of Dakar) and was diagnosed for malaria on the basis of positive malaria rapid diagnostic test (RDT) specific to Plamodium falciparum...
January 11, 2017: Malaria Journal
https://www.readbyqxmd.com/read/28076469/scoring-clinical-signs-can-help-diagnose-canine-visceral-leishmaniasis-in-a-highly-endemic-area-in-brazil
#4
Kleverton Ribeiro da Silva, Vitor Rosa Ramos de Mendonça, Kellen Matuzzy Silva, Leopoldo Fabrício Marçal do Nascimento, Antonio Ferreira Mendes-Sousa, Flaviane Alves de Pinho, Manoel Barral-Netto, Aldina Maria Prado Barral, Maria do Socorro Pires E Cruz
Canine visceral leishmaniasis (CVL) diagnosis is still a challenge in endemic areas with limited diagnostic resources. This study proposes a score with the potential to distinguish positive CVL cases from negative ones. We studied 265 dogs that tested positive for CVL on ELISA and parasitological tests. A score ranging between 0 and 19 was recorded on the basis of clinical signs. Dogs with CVL had an overall higher positivity of the majority of clinical signs than did dogs without CVL or with ehrlichiosis. Clinical signs such as enlarged lymph nodes (83...
January 1, 2017: Memórias do Instituto Oswaldo Cruz
https://www.readbyqxmd.com/read/28062991/complementary-description-of-ergasilus-arthrosis-roberts-1969-copepoda-poecilostomatoida-ergasilidae-a-new-parasite-of-cichlid-teleosts-in-southeast-mexico
#5
María Isabel Jiménez-García, Eduardo Suárez-Morales
During a parasitological survey of the ichthyofauna of Lake Catemaco, a freshwater system in the Mexican State of Veracruz, the widespread copepod Ergasilus arthrosis Roberts, 1969 was recovered from two cichlid teleosts, Mayaheros urophthalmus (Günther) and Oreochromis sp. This is the first confirmed record of this copepod species outside of the United States and from Mexico; its finding as a parasite of cichlids represents an expansion of the known host range for this copepod. The local prevalence and intensity of infection of E...
January 2017: Systematic Parasitology
https://www.readbyqxmd.com/read/28056021/comparison-of-doxycycline-minocycline-doxycycline-plus-albendazole-and-albendazole-alone-in-their-efficacy-against-onchocerciasis-in-a-randomized-open-label-pilot-trial
#6
Ute Klarmann-Schulz, Sabine Specht, Alexander Yaw Debrah, Linda Batsa, Nana Kwame Ayisi-Boateng, Jubin Osei-Mensah, Yusif Mubarik, Peter Konadu, Arcangelo Ricchiuto, Rolf Fimmers, Sandra Arriens, Bettina Dubben, Louise Ford, Mark Taylor, Achim Hoerauf
: The search for new macrofilaricidal drugs against onchocerciasis that can be administered in shorter regimens than required for doxycycline (DOX, 200mg/d given for 4-6 weeks), identified minocycline (MIN) with superior efficacy to DOX. Further reduction in the treatment regimen may be achieved with co-administration with standard anti-filarial drugs. Therefore a randomized, open-label, pilot trial was carried out in an area in Ghana endemic for onchocerciasis, comprising 5 different regimens: the standard regimen DOX 200mg/d for 4 weeks (DOX 4w, N = 33), the experimental regimens MIN 200mg/d for 3 weeks (MIN 3w; N = 30), DOX 200mg/d for 3 weeks plus albendazole (ALB) 800mg/d for 3 days (DOX 3w + ALB 3d, N = 32), DOX 200mg/d for 3 weeks (DOX 3w, N = 31) and ALB 800mg for 3 days (ALB 3d, N = 30)...
January 2017: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/28045920/alterations-in-evoked-otoacoustic-emissions-by-the-use-of-meglumine-antimoniate-in-american-tegumentary-leishmaniasis-patients
#7
Débora Cristina de Oliveira Bezerra, Renata Oliveira de Barcelos, Ellen Carvalho de Castro, Claudia Cristina Jardim Duarte, Raquel de Vasconcellos Carvalhaes Oliveira, Tania Salgado de Sousa Torraca, Maria Helena de Araújo-Melo, Frederico Pereira Bom Braga, Benivaldo Ramos Ferreira Terceiro, Lúcia Regina do Nascimento Brahim Paes, Armando de Oliveira Schubach, Cláudia Maria Valete-Rosalino
INTRODUCTION: Tegumentary Leishmaniasis (TL) is a neglected, non-contagious, infectious disease, caused by different protozoa species of the Leishmania genus that affects skin and mucous membranes. Meglumine Antimoniate (MA), the first drug of choice for TL treatment in Brazil, has already been associated with cochlear toxicity, which is defined as damages of the cochlea caused by exposure to chemical substances, resulting in reversible or irreversible hearing loss. Auditory monitoring for cochlear toxicity aims at the early detection of auditory disorders, enabling, when possible, hearing to be preserved or an early auditory rehabilitation...
2017: PloS One
https://www.readbyqxmd.com/read/28043379/use-of-a-commercial-serologic-test-for-angiostrongylus-vasorum-for-the-detection-of-a-chabaudi-in-wildcats-and-a-daskalovi-in-badgers
#8
Georgiana Deak, Călin Mircea Gherman, Angela Monica Ionică, Aikaterini Alexandra Daskalaki, Ioana Adriana Matei, Gianluca D'Amico, Cristian Domşa, Nikola Pantchev, Andrei Daniel Mihalca, Vasile Cozma
Three species of the genus Angiostrongylus are known to infect European carnivores: A. vasorum (mainly in canids but also in other carnivores), A. chabaudi (in felids) and A. daskalovi (in mustelids). A. vasorum is responsible for clinically severe disease in domestic dogs, most commonly diagnosed based on fecal examination and serological detection of circulating antigens. Considering the poorly known host range and the challenging larval differentiation in the feces between the three species of Angiostrongylus infecting European carnivores, our aim was to evaluate the cross-reactivity of A...
January 15, 2017: Veterinary Parasitology
https://www.readbyqxmd.com/read/28032106/canine-visceral-leishmaniasis-in-wild-canines-fox-jackal-and-wolf-in-northeastern-iran-using-parasitological-serological-and-molecular-methods
#9
Mehdi Mohebali, Kourosh Arzamani, Zabiholah Zarei, Behnaz Akhoundi, Homa Hajjaran, Saber Raeghi, Zahra Heidari, Seyed Mousa Motavalli-Haghi, Samira Elikaee, Ahmad Mousazadeh-Mojarrad, Zahra Kakoei
BACKGROUND: Although many studies had been conducted on various aspects of canine visceral leishmaniasis (CVL) in domestic dogs in the endemic areas of Iran, investigations on CVL in wild canines are rare. METHODS: This is a cross-sectional study was conducted from December 2012 to 2013 in northeast of Iran where human VL is endemic. Wild canines were trapped around the areas where human VL cases had been previously identified. Wild canines were collected and examined both clinically and serologically using direct agglutination test (DAT)...
December 2016: Journal of Arthropod-borne Diseases
https://www.readbyqxmd.com/read/28031550/bug-smash-bug-splash-a-case-report-of-an-unusual-transmission-of-american-trypanosomiasis-with-a-brief-review-of-the-literature
#10
Rafael Hernán Navarrete-Sandoval, Maximiliano Servín-Rojas
BACKGROUND Chagas disease is a chronic parasitosis transmitted by the inoculation of infected triatomine feces into wounds or conjunctival sac, transfusion, congenitally, organ transplantation, and ingestion of contaminated food. The disease is classified into an acute and chronic phase; the latter is a life-long infection that can be asymptomatic or progress to cardiac or digestive complications. CASE REPORT We report a case of acute-phase Chagas disease, transmitted by the splash of gut content from an infected triatomine into the conjunctival mucosa...
December 29, 2016: American Journal of Case Reports
https://www.readbyqxmd.com/read/28018646/scratch-that-itch-revisiting-links-between-self-directed-behaviour-and-parasitological-social-and-environmental-factors-in-a-free-ranging-primate
#11
Julie Duboscq, Valéria Romano, Cédric Sueur, Andrew J J MacIntosh
Different hypotheses explain variation in the occurrence of self-directed behaviour such as scratching and self-grooming: a parasite hypothesis linked with ectoparasite load, an environmental hypothesis linked with seasonal conditions and a social hypothesis linked with social factors. These hypotheses are not mutually exclusive but are often considered separately. Here, we revisited these hypotheses together in female Japanese macaques (Macaca fuscata fuscata) of Kōjima islet, Japan. We input occurrences of scratching and self-grooming during focal observations in models combining parasitological (lice load), social (dominance rank, social grooming, aggression received and proximity), and environmental (rainfall, temperature and season) variables...
November 2016: Royal Society Open Science
https://www.readbyqxmd.com/read/28009386/detection-of-giardia-intestinalis-infections-in-polish-soldiers-deployed-to-afghanistan
#12
Krzysztof Korzeniewski, Monika Konior, Alina Augustynowicz, Anna Lass, Ewa Kowalska
BACKGROUND: Members of the Polish Military Contingent (PMC) have been stationed in Afghanistan since 2002. They typically serve in areas characterised by low standards of sanitation which often leads to the development of food- and waterborne diseases. The aim of the study was to evaluate the prevalence of Giardia intestinalis infections among Polish soldiers deployed to Afghanistan. The research study was conducted as part of a programme for prevention of parasitic diseases of the gastrointestinal tract run by the Polish Armed Forces...
2016: International Maritime Health
https://www.readbyqxmd.com/read/28007483/bovine-trypanosomosis-and-vector-density-in-omo-ghibe-tsetse-belt-south-ethiopia
#13
Rahmeto Abebe, Solomon Gute, Ijigu Simon
African animal trypanosomosis (AAT) is a parasitic disease that causes serious economic losses in livestock from anemia, loss of condition, emaciation and death in untreated cases. It is one of the major constraints to improved livestock production and productivity in Ethiopia. Entomological and parasitological surveys were conducted in the Omo-Ghibe tsetse belt of south Ethiopia to estimate the prevalence of bovine trypanosomosis and the apparent tsetse density (AD), and identify the potential risk factors...
December 19, 2016: Acta Tropica
https://www.readbyqxmd.com/read/27988484/fixed-dose-artesunate-amodiaquine-combination-vs-chloroquine-for-treatment-of-uncomplicated-blood-stage-p-vivax-infection-in-the-brazilian-amazon-an-open-label-randomized-controlled-trial
#14
Andre M Siqueira, Aline C Alencar, Gisely C Melo, Belisa L Magalhaes, Kim Machado, Aristóteles C Alencar Filho, Andrea Kuehn, Marly M Marques, Monica Costa Manso, Ingrid Felger, José L F Vieira, Valerie Lameyre, Claudio T Daniel-Ribeiro, Marcus V G Lacerda
BACKGROUND: Despite increasing evidence of the development of Plasmodium vivax chloroquine (CQ) resistance, there have been no trials comparing its efficacy with that of artemisinin-based combination therapies (ACTs) in Latin America. METHODS: This randomized controlled trial compared the antischizontocidal efficacy and safety of a 3-day supervised treatment of the fixed-dose combination artesunate-amodiaquine Winthrop(®) (ASAQ) versus CQ for treatment of uncomplicated P...
January 15, 2017: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/27983970/the-new-situation-of-cutaneous-leishmaniasis-after-syrian-civil-war-in-gaziantep-city-southeastern-region-of-turkey
#15
Ahmet Özkeklikçi, Mehmet Karakuş, Yusuf Özbel, Seray Töz
Cutaneous leishmaniasis (CL) is an important public health problem with around 2.000 autochthonous reported cases each year in Turkey. Due to the civil war in Syria, Turkey received around three million refugees and they are mainly located at either camps or homes in south/southeastern part of Turkey. In the present study, we aimed to collect samples from CL suspected patients admitting to State Hospital in Gaziantep City and perform parasitological and DNA-based techniques for diagnosis as well as species identification of the parasite for better understanding the prevalence of each species among Turkish and Syrian patients in the region...
February 2017: Acta Tropica
https://www.readbyqxmd.com/read/27968827/operational-challenges-to-the-1-3-7-surveillance-strategy-for-malaria-elimination-in-china-a-qualitative-study
#16
Guang-Yu Lu, Yao-Bao Liu, Claudia Beiersmann, Yu Feng, Jun Cao, Olaf Müller
BACKGROUND: China aims to eliminate malaria by 2020. In 2012, China launched its 1-3-7 malaria surveillance strategy, which refers to case reporting within one day, case investigation within three days, and focus investigation and public health actions within seven days. The aim of this study was to identify operational challenges to the 1-3-7 surveillance strategy. METHODS: This qualitative study was conducted in northwestern (Gansu Province) and southeastern (Jiangsu Province) China...
October 2016: Lancet
https://www.readbyqxmd.com/read/27965165/suspected-cases-of-cholangiocarcinoma-seen-in-reference-hospitals-in-lao-people-s-democratic-republic
#17
Phonepasong Ayé Soukhathammavong, Youthanavanh Vonghachack, Christoph Hatz, Kongsap Akkhavong, Peter Odermatt
Cholangiocarcinoma (CCA) poses a significant public health problem in Southeast Asia, with chronic Opisthorchis viverrini infection being the main risk factor. Epidemiological data on CCA is not available for Lao People Democratic Republic (Lao PDR), though there is a high prevalence of O. viverrini infection in the country. A hospital record-based retrospective study was carried out in six referral hospitals (four in the capital city, one in Savannakhet, one in Pakse) to assess the number of suspected CCA cases admitted between January 2006 and December 2010...
December 11, 2016: Parasitology International
https://www.readbyqxmd.com/read/27958200/update-on-pathology-of-ocular-parasitic-disease
#18
REVIEW
Dipankar Das, Varsha Ramachandra, Saidul Islam, Harsha Bhattacharjee, Jyotirmay Biswas, Akanksha Koul, Panna Deka, Apurba Deka
Parasites are a group of eukaryotic organisms that may be free-living or form a symbiotic or parasitic relationship with the hosts. Consisting of over 800,000 recognized species, parasites may be unicellular (Protozoa) or multicellular (helminths and arthropods). The association of parasites with human population started long before the emergence of civilization. Parasitic zoonotic diseases are prevalent worldwide including India. Appropriate epidemiological data are lacking on existing zoonotic parasitic diseases, and newer diseases are emerging in our scenario...
November 2016: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/27956049/parasitological-and-molecular-surveys-reveal-high-rates-of-infection-with-vector-borne-pathogens-and-clinical-anemia-signs-associated-with-infection-in-cattle-from-two-important-livestock-areas-in-colombia
#19
Jeiczon Jaimes-Dueñez, Omar Triana-Chávez, Ana M Mejía-Jaramillo
In Colombia, vector-borne diseases are one of the most important problems in the livestock industry. The present study reports parasitological and molecular surveys of vector-borne pathogens in cattle from two high-value livestock areas in Colombia. A total of 464 samples (226 from Antioquia and 238 from Arauca) were analyzed. While the blood smear analysis identified 98 (21.1%), 14 (3.0%) and 30 (6.5%) positive samples for Anaplasma spp., Babesia spp. and Trypanosoma spp., respectively, the molecular methods indicated that 275 (59...
December 7, 2016: Ticks and Tick-borne Diseases
https://www.readbyqxmd.com/read/27955687/decline-in-transmission-of-schistosomiasis-mansoni-in-oman
#20
Idris Al Abaidani, Seif Al-Abri, Mahmoud Shaban, Satish L Ghugey, Salem Al Kathery, Khalid Al-Mashikhi, Amadou Garba, Albis Francesco Gabrielli
BACKGROUND: Intestinal schistosomiasis due to Schistosoma mansoni was first reported in Oman in 1979. We describe the trend in parasitological and serological prevalence of human infection with S. mansoni in the endemic area over the period 1982-2014, and the compliance of data generated by the national monitoring and evaluation system with schistosomiasis elimination criteria set by the Ministry of Health of Oman. METHODS: Parasitological and serological assessments were carried out on population (mainly children) living in the area at risk for schistosomiasis in Dhofar, the country's only endemic Governorate, for a period of over 30 years...
December 12, 2016: Infectious Diseases of Poverty
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