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Interoception

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https://www.readbyqxmd.com/read/28325028/tracking-intrinsic-connectivity-brain-network-features-during-successive-pseudo-resting-states-and-interoceptive-task-fmri
#1
Behnaz Jarrahi, Dante Mantini
Advanced multivariate analyses of functional magnetic resonance imaging (fMRI) data based on blood oxygen level-dependent (BOLD) contras have revealed that the human brain organizes its activities into multiple intrinsic connectivity networks (ICNs). Several fMRI studies have evaluated the modulations of these networks during different cognitive or emotional tasks using blind source separation techniques particularly the independent component analysis (ICA). In this exploratory study, we applied ICA methodology to examine ICN modulations under different interoceptive conditions...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28325027/identifying-the-effects-of-visceral-interoception-on-human-brain-connectome-a-multivariate-analysis-of-covariance-of-fmri-data
#2
Behnaz Jarrahi, Dante Mantini
Sources of variations in the neural circuitry of the human brain and interrelationship between intrinsic connectivity networks (ICNs) are still a matter of debate and ongoing research. Here, we applied a multivariate analysis of covariance (MANCOVA) based on high-dimensional independent component analysis (ICA) to identify the effects of interoception and related variables on human brain connectome. Fifteen healthy right-handed subjects (all females, age range 21 - 48 years; mean age = 30.3, SD = 8.7 years) underwent a blood-oxygen-level-dependent (BOLD) functional magnetic resonance imaging (fMRI) that included continuous intravesical saline infusion and drainage...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28287798/a-randomized-clinical-trial-targeting-anxiety-sensitivity-for-patients-with-suicidal-ideation
#3
Norman B Schmidt, Aaron M Norr, Nicholas P Allan, Amanda M Raines, Daniel W Capron
OBJECTIVE: Anxiety sensitivity (AS) is a well-established transdiagnostic risk factor for anxiety and mood psychopathology including suicide. A variety of interventions using cognitive-behavioral skills as well as cognitive bias modification (CBM) suggest that AS can be quickly and effectively reduced in nonclinical and nontreatment seeking samples. However, it is unclear whether AS reduction protocols will have efficacy for more severe clinical samples. Moreover, the combination of cognitive-behavioral techniques with CBM focused on changing interpretation bias (CBM-I) related to AS has not been evaluated...
March 13, 2017: Journal of Consulting and Clinical Psychology
https://www.readbyqxmd.com/read/28287195/-pilot-study-on-nutritional-and-eating-disorders-in-children-and-mood-disorders-comorbidity-or-prodromal-traits
#4
Paola Cimbolli, Álvaro Quiñones, Carla Ugarte, Adele De Pascale
INTRODUCTION: Both children affected by nutritional and eating disorders (ED) and adults with bipolar disorder (BD) display symptoms of deficient emotional self-regulation, which can present in different forms. If we observe the clinical and developmental histories of individuals affected by EDs and BD, based on a cognitive systemic post-rationalist approach, we can hypothesise a continuum between the two disorders. The aim of this pilot study is to support the hypothesis - from an explanatory rather than a non-descriptive approach - that EDs and BD are the possible result of issues tied to biological and psychological self-regulation...
January 2017: Rivista di Psichiatria
https://www.readbyqxmd.com/read/28279667/preclinical-assessment-of-the-abuse-potential-of-the-orexin-receptor-antagonist-suvorexant
#5
Stephanie Born, David V Gauvin, Suman Mukherjee, Richard Briscoe
Suvorexant (Belsomra(®)) is a dual orexin receptor antagonist approved for the treatment of insomnia. Because of its pharmacology within the central nervous system, intended therapeutic indication, and first-in-class status, an assessment of suvorexant abuse liability potential was required prior to marketing approval. The nonclinical abuse liability potential studies for suvorexant included: 1) rat drug-dependence model to assess physical dependence following abrupt cessation; 2) rat drug-discrimination model to examine the potential similarity of the interoceptive or subjective effects of suvorexant to those elicited by zolpidem and morphine; 3) self-administration model to assess the relative reinforcing efficacy of suvorexant in rhesus monkeys conditioned to self-administer methohexital...
March 6, 2017: Regulatory Toxicology and Pharmacology: RTP
https://www.readbyqxmd.com/read/28278494/emotions-in-motion-myofascial-interoception
#6
Bruno Bordoni, Fabiola Marelli
No abstract text is available yet for this article.
March 10, 2017: Complement Med Res
https://www.readbyqxmd.com/read/28277403/methylphenidate-enhances-grip-force-and-alters-brain-connectivity
#7
Michael King, Laurie H Rauch, Samantha J Brooks, Dan J Stein, Kai Lutz
INTRODUCTION: A central fatigue theory proposes that force output during fatiguing exercise is limited to maintain homeostasis. The self-awareness of the body's homeostatic state is known as interoception. Brain regions thought to play a role in interoception, such as the insular and orbital frontal cortex, have been proposed as sites for the upstream regulation of fatiguing exercise. Methylphenidate (MPH) can improve force output during exercise and may alter central processes during fatiguing exercise...
March 8, 2017: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/28258747/psychotherapy-with-somatosensory-stimulation-for-endometriosis-associated-pain-the-role-of-the-anterior-hippocampus
#8
Florian Beissner, Christine Preibisch, Annemarie Schweizer-Arau, Roxana M Popovici, Karin Meissner
BACKGROUND: Endometriosis is a gynecological disorder affecting 6%-10% of all women in their reproductive age. There is an emerging view in the literature that psychological trauma plays a central role in the pathogenesis of pelvic pain, one of the core symptoms of endometriosis. Here we report central nervous system mechanisms of a novel combination of psychotherapy and somatosensory stimulation that has recently shown remarkable effects in reducing pain, anxiety, and depressive symptoms in these patients...
January 16, 2017: Biological Psychiatry
https://www.readbyqxmd.com/read/28251663/emotion-dysregulation-and-autonomic-responses-to-film-rumination-and-body-awareness-extending-psychophysiological-research-to-a-naturalistic-clinical-setting-and-a-chemically-dependent-female-sample
#9
Sheila E Crowell, Cynthia J Price, Megan E Puzia, Mona Yaptangco, Sunny Chieh Cheng
Substance use is a complex clinical problem characterized by emotion dysregulation and daily challenges that can interfere with laboratory research. Thus, few psychophysiological studies examine autonomic and self-report measures of emotion dysregulation with multidiagnostic, chemically dependent samples or extend this work into naturalistic settings. In this study, we used a within-subject design to examine changes in respiratory sinus arrhythmia (RSA), electrodermal activity (EDA), and self-reported affect across three tasks designed to elicit distinct psychophysiological and emotional response patterns...
March 2, 2017: Psychophysiology
https://www.readbyqxmd.com/read/28238679/how-does-paying-attention-improve-sexual-functioning-in-women-a%C3%A2-review-of-mechanisms
#10
REVIEW
Nikita Arora, Lori A Brotto
INTRODUCTION: Female sexual dysfunction (FSD), consisting of a constellation of distressing sexual symptoms, is highly prevalent worldwide. Given the central role played by psychological factors in the development of FSD, psychologically and in particular mindfulness-based interventions have arisen as potential treatment options for women. Although mindfulness-based interventions have been evaluated in samples of women with gynecologic cancer; a history of sexual abuse; multiple sclerosis; and spinal cord injury; and provoked vestibulodynia, the mechanisms by which mindfulness leads to improvements in sexual functioning are largely unstudied...
February 23, 2017: Sexual Medicine Reviews
https://www.readbyqxmd.com/read/28231304/a-four-day-western-style-dietary-intervention-causes-reductions-in-hippocampal-dependent-learning-and-memory-and-interoceptive-sensitivity
#11
Tuki Attuquayefio, Richard J Stevenson, Megan J Oaten, Heather M Francis
In animals, a Western style diet-high in saturated fat and added sugar-causes impairments in hippocampal-dependent learning and memory (HDLM) and perception of internal bodily state (interoception). In humans, while there is correlational support for a link between Western-style diet, HDLM, and interoception, there is as yet no causal data. Here, healthy individuals were randomly assigned to consume either a breakfast high in saturated fat and added sugar (Experimental condition) or a healthier breakfast (Control condition), over four consecutive days...
2017: PloS One
https://www.readbyqxmd.com/read/28227771/tracking-intrinsic-connectivity-brain-network-features-during-successive-pseudo-resting-states-and-interoceptive-task-fmri
#12
Behnaz Jarrahi, Dante Mantini, Behnaz Jarrahi, Dante Mantini, Behnaz Jarrahi, Dante Mantini
Advanced multivariate analyses of functional magnetic resonance imaging (fMRI) data based on blood oxygen level-dependent (BOLD) contras have revealed that the human brain organizes its activities into multiple intrinsic connectivity networks (ICNs). Several fMRI studies have evaluated the modulations of these networks during different cognitive or emotional tasks using blind source separation techniques particularly the independent component analysis (ICA). In this exploratory study, we applied ICA methodology to examine ICN modulations under different interoceptive conditions...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227769/identifying-the-effects-of-visceral-interoception-on-human-brain-connectome-a-multivariate-analysis-of-covariance-of-fmri-data
#13
Behnaz Jarrahi, Dante Mantini, Behnaz Jarrahi, Dante Mantini, Behnaz Jarrahi, Dante Mantini
Sources of variations in the neural circuitry of the human brain and interrelationship between intrinsic connectivity networks (ICNs) are still a matter of debate and ongoing research. Here, we applied a multivariate analysis of covariance (MANCOVA) based on high-dimensional independent component analysis (ICA) to identify the effects of interoception and related variables on human brain connectome. Fifteen healthy right-handed subjects (all females, age range 21 - 48 years; mean age = 30.3, SD = 8.7 years) underwent a blood-oxygen-level-dependent (BOLD) functional magnetic resonance imaging (fMRI) that included continuous intravesical saline infusion and drainage...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28212526/can-you-feel-the-body-that-you-see-on-the-relationship-between-interoceptive-accuracy-and-body-image
#14
Giorgia Zamariola, Flavia Cardini, Emanuel Mian, Andrea Serino, Manos Tsakiris
Interoception and exteroception for body signals are two different ways of perceiving the self: the first from within, the second from outside. We investigated the relationship between Interoceptive Accuracy (IAcc) and external perception of the body and we tested if seeing the body from an external perspective can affect IAcc. Fifty-two healthy female subjects performed a standard heartbeat perception task to assess the IAcc, before and after the Body Image Revealer (BIR), which is a body perception task designed to assess the different aspects of body-image...
March 2017: Body Image
https://www.readbyqxmd.com/read/28211586/social-cognition-and-emotional-functioning-in-patients-with-binge-eating-disorder
#15
Matteo Aloi, Marianna Rania, Mariarita Caroleo, Pasquale De Fazio, Cristina Segura-García
OBJECTIVE: This study aims to evaluate the theory of mind ability in a sample of obese patients with and without binge eating disorder (BED) and to explore the correlations between emotional and clinical assessments. METHODS: Overall, 20 non-BED, 16 under-threshold BED and 22 BED obese patients completed a battery of tests assessing social cognition and eating disorder psychopathology. RESULTS: Binge eating disorder, non-BED and under-threshold-BED obese patients showed similar ability to recognise others' emotions, but BED obese patients exhibited a deficit in recognising their own emotions as demonstrated by more impaired levels of alexithymia and interoceptive awareness and were more depressed...
February 17, 2017: European Eating Disorders Review: the Journal of the Eating Disorders Association
https://www.readbyqxmd.com/read/28210930/emotion-specific-nocebo-effects-an-fmri-study
#16
Anne Schienle, Carina Höfler, Sonja Übel, Albert Wabnegger
The neurobiological mechanisms of nocebos are still poorly understood. Thirty-eight women participated in a 'smell study' using functional magnetic resonance imaging. They were presented with an odorless stimulus (distilled water) together with the verbal suggestion that this fluid has an aversive odor which enhances disgust feelings. The nocebo was presented while the participants viewed disgusting, fear-inducing, and neutral images. Participants' affective and neuronal responses during nocebo administration were compared with those in a control condition without nocebo...
February 16, 2017: Brain Imaging and Behavior
https://www.readbyqxmd.com/read/28186381/psychiatric-and-psychological-aspects-in-the-ehlers-danlos-syndromes
#17
Antonio Bulbena, Carolina Baeza-Velasco, Andrea Bulbena-Cabré, Guillem Pailhez, Hugo Critchley, Pradeep Chopra, Nuria Mallorquí-Bagué, Charissa Frank, Stephen Porges
There is increasing amount of evidence pointing toward a high prevalence of psychiatric conditions among individuals with hypermobile type of Ehlers-Danlos syndrome (JHS/hEDS). A literature review confirms a strong association between anxiety disorders and JHSh/hEDS, and there is also limited but growing evidence that JHSh/hEDS is also associated with depression, eating, and neuro-developmental disorders as well as alcohol and tobacco misuse. The underlying mechanisms behind this association include genetic risks, autonomic nervous system dysfunction, increased exteroceptive and interoceptive mechanisms and decreased proprioception...
February 10, 2017: American Journal of Medical Genetics. Part C, Seminars in Medical Genetics
https://www.readbyqxmd.com/read/28167076/brain-network-alterations-in-the-inflammatory-soup-animal-model-of-migraine
#18
Lino Becerra, James Bishop, Gabi Barmettler, Vanessa Kainz, Rami Burstein, David Borsook
Advances in our understanding of the human pain experience have shifted much of the focus of pain research from the periphery to the brain. Current hypotheses suggest that the progression of migraine depends on abnormal functioning of neurons in multiple brain regions. Accordingly, we sought to capture functional brain changes induced by the application of an inflammatory cocktail known as inflammatory soup (IS), to the dura mater across multiple brain networks. Specifically, we aimed to determine whether IS alters additional neural networks indirectly related to the primary nociceptive pathways via the spinal cord to the thalamus and cortex...
April 1, 2017: Brain Research
https://www.readbyqxmd.com/read/28163798/phenomenological-fingerprints-of-four-meditations-differential-state-changes-in-affect-mind-wandering-meta-cognition-and-interoception-before-and-after-daily-practice-across-9%C3%A2-months-of-training
#19
Bethany E Kok, Tania Singer
Despite increasing interest in the effects of mental training practices such as meditation, there is much ambiguity regarding whether and to what extent the various types of mental practice have differential effects on psychological change. To address this gap, we compare the effects of four common meditation practices on measures of state change in affect, mind-wandering, meta-cognition, and interoception. In the context of a 9-month mental training program called the ReSource Project, 229 mid-life adults (mean age 41) provided daily reports before and after meditation practice...
2017: Mindfulness
https://www.readbyqxmd.com/read/28162895/the-brain-basis-for-misophonia
#20
Sukhbinder Kumar, Olana Tansley-Hancock, William Sedley, Joel S Winston, Martina F Callaghan, Micah Allen, Thomas E Cope, Phillip E Gander, Doris-Eva Bamiou, Timothy D Griffiths
Misophonia is an affective sound-processing disorder characterized by the experience of strong negative emotions (anger and anxiety) in response to everyday sounds, such as those generated by other people eating, drinking, chewing, and breathing [1-8]. The commonplace nature of these sounds (often referred to as "trigger sounds") makes misophonia a devastating disorder for sufferers and their families, and yet nothing is known about the underlying mechanism. Using functional and structural MRI coupled with physiological measurements, we demonstrate that misophonic subjects show specific trigger-sound-related responses in brain and body...
February 20, 2017: Current Biology: CB
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