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https://www.readbyqxmd.com/read/28653867/association-between-the-single-assessment-numeric-evaluation-and-the-western-ontario-and-mcmaster-universities-osteoarthritis-index
#1
Brian Pietrosimone, Brittney A Luc, Austin Duncan, Susan A Saliba, Joseph M Hart, Christopher D Ingersoll
CONTEXT:   Patient-reported outcomes (PROs) evaluate how patients describe symptoms as well as level of physical function or quality of life. The Western Ontario and McMaster Universities Osteoarthritis (WOMAC) Index is one of the most common PROs used to assess disability in patients with knee osteoarthritis (OA), yet the Single Assessment Numeric Evaluation (SANE) is a single-question instrument that may improve the efficiency associated with the measurement of patient function. OBJECTIVE:   To determine the associations between (1) SANEFunction and the physical dysfunction subsection of the WOMAC index (WOMACDysfunction) before rehabilitation and after a 4-week therapeutic exercise intervention as well as (2) the percentage change in SANEFunction and WOMACDysfunction in people with knee OA after 4 weeks of therapeutic exercise...
June 2, 2017: Journal of Athletic Training
https://www.readbyqxmd.com/read/28642646/intensity-duration-and-type-of-physical-activity-required-to-improve-function-in-knee-osteoarthritis
#2
Ricardo Akihiro Kirihara, Fellipe Bravim Catelan, Fabiane Elize Sabino DE Farias, Cleidnéia Aparecida Clemente DA Silva, Claudia Helena DE Azevedo Cernigoy, Márcia Uchoa DE Rezende
OBJECTIVE: To evaluate the effects of physical activity intensity, type and duration in patients with knee osteoarthritis (KOA) . METHODS: A retrospective study of 195 KOA patients who were followed for two years after receiving educational material about KOA with or without attending classes. The patients were evaluated at baseline and 24 months. At the evaluations, the patients answered questionnaires pertaining to pain and function (WOMAC, Lequesne, VAS and SF-36); reported the intensity, duration and type of exercise performed per week; and performed the Timed Up & Go (TUG) and Five Times Sit-to-Stand (FTSST) tests ...
January 2017: Acta Ortopedica Brasileira
https://www.readbyqxmd.com/read/28642645/parqve-project-arthritis-recovering-quality-of-life-through-education-two-year-results
#3
Márcia Uchoa DE Rezende, Renato Frucchi, Alexandre Felício Pailo, Gustavo Constantino DE Campos, Thiago Pasqualin, Marcelo Issao Hissadomi
OBJECTIVE: To evaluate the effects of a multi-professional educational program in patients with knee osteoarthritis (KOA) . METHODS: Prospective randomized controlled trial with 195 KOA patients. One group was submitted to two-day lectures and received educational material about KOA (Class group), and the control group received the educational material only. Patients were evaluated at baseline, twelve and 24 months. At evaluation, patients answered pain and functional questionnaires (WOMAC, Lequesne, VAS and SF-36); reported the intensity of exercise per week; measured the body fat percentage, weight and height to estimate body mass index (BMI); and performed Timed Up & Go (TUG) and Five-Times-Sit-to-Stand (FTSST) tests ...
January 2017: Acta Ortopedica Brasileira
https://www.readbyqxmd.com/read/28638680/genetic-influence-of-growth-and-differentiation-factor-5-gene-polymorphism-104t-c-on-the-development-of-knee-osteoarthritis-and-its-association-with-disease-severity
#4
Mervat I Abd Elazeem, Enas Abolkheir Abdelaleem, Rabab A Mohamed
OBJECTIVE: The growth and differentiation factor 5 (GDF5) gene is recognized for its role in the development, repair, and maintenance of cartilage and bone. The present case-control study was conducted to detect the genetic association between GDF5 (+104T/C) single-nucleotide polymorphism (SNP) and primary knee osteoarthritis (KOA), as well as the possible association of SNP with the severity of KOA. MATERIAL AND METHODS: The study included 50 patients with primary KOA and 50 healthy control subjects...
June 2017: European Journal of Rheumatology
https://www.readbyqxmd.com/read/28638679/decrease-of-serum-biomarker-of-type-ii-collagen-degradation-coll2-1-by-intra-articular-injection-of-an-autologous-plasma-rich-platelet-in-patients-with-unilateral-primary-knee-osteoarthritis
#5
Rasha Mohamed Fawzy, Nashwa Ismail Hashaad, Amira Ibrahim Mansour
OBJECTIVE: This study aimed to evaluate the effect of one dose of intra-articular injection of (PRP) in the knee joint on a specific osteoarthritis (OA) serum biomarker of cartilage degeneration, Collagen 2-1 (Coll2-1), over a short period of 3 months. The aim extended to clarify the effect of PRP on the functional status of the osteoarthritic knee joint. MATERIAL AND METHODS: Sixty patients with primary unilateral knee OA were enrolled in this study. They were subdivided according to Kellgren-Lawrence grading scale (KL) into (Group I): including patients with KL grade < 3 and (Group II): including patients with KL grade ≥3...
June 2017: European Journal of Rheumatology
https://www.readbyqxmd.com/read/28632587/the-clinical-outcome-of-computer-navigated-compared-with-conventional-knee-arthroplasty-in-the-same-patients-a-prospective-randomized-double-blind-long-term-study
#6
Young-Hoo Kim, Jang-Won Park, Jun-Shik Kim
BACKGROUND: The available comparative studies of computer navigation-assisted and conventional knee arthroplasties have short-term follow-up periods. Therefore, the clinical benefits after long-term follow-up are not clear. The purposes of the current long-term study were to compare clinical outcomes, alignment of the knee components, prevalence of aseptic loosening of the components, implant survival, and complications of total knee arthroplasties performed with and without computer navigation...
June 21, 2017: Journal of Bone and Joint Surgery. American Volume
https://www.readbyqxmd.com/read/28631701/-clinical-features-of-osteoarthritis-in-patients-with-metabolic-syndrome
#7
L V Vasilyeva, D I Lakhin
AIM: To estimate clinical and laboratory parameters in patients with osteoarthritis (OA) and in those with OA and metabolic syndrome (MS). SUBJECTS AND METHODS: 164 patients with OA were examined and divided into 2 groups of 82 people: a study group (patients with MS) and a control one (those without MS). OA was defined according to the diagnostic criteria described by R.D. Althmann (1995). MS was identified based on the criteria developed by the International Diabetes Federation (2005)...
2017: Terapevticheskiĭ Arkhiv
https://www.readbyqxmd.com/read/28631083/is-there-a-relationship-between-serum-ox-ldl-oxidative-stress-and-pon1-in-knee-osteoarthritis
#8
Cemil Ertürk, Mehmet Akif Altay, Ali Bilge, Hakim Çelik
Previous in vitro studies have shown that oxidized low-density lipoprotein (ox-LDL) plays a role in the pathogenesis of osteoarthritis (OA). Paraoxonase-1 (PON1) protects both low-density lipoproteins (LDLs) and high-density lipoprotein (HDLs) against oxidative damage from circulating cells. In addition, PON1 is inactivated by ox-LDL and preserved by antioxidants. However, the relationship between serum ox-LDL, oxidative stress, and PON1 in knee OA remains unclear. Therefore, we investigated ox-LDL association with oxidative stress and PON1 in knee OA, and evaluated their relationships using radiological and clinical parameters...
June 19, 2017: Clinical Rheumatology
https://www.readbyqxmd.com/read/28630735/arthroscopic-acetabuloplasty-without-labral-detachment-for-focal-pincer-type-impingement-a-minimum-2-year-follow-up
#9
Fernando M Comba, Pablo A Slullitel, Pedro Bronenberg, Gerardo Zanotti, Martin A Buttaro, Francisco Piccaluga
In order to access and resect the acetabular rim, arthroscopic acetabuloplasty was described with labral detachment. When the chondrolabral junction remains intact, acetabuloplasty and labral refixation can be performed maintaining an unharmed labrum. We aimed to evaluate the outcome of a group of patients treated with arthroscopic acetabuloplasty without labral detachment. During the study period, we retrospectively analysed 44 patients with pincer-type o combined impingement and an intact chondroblabral junction, with an average follow-up of 32 months (range: 27-38)...
July 2017: Journal of Hip Preservation Surgery
https://www.readbyqxmd.com/read/28629466/intra-articular-injection-in-the-knee-of-adipose-derived-stromal-cells-stromal-vascular-fraction-and-platelet-rich-plasma-for-osteoarthritis
#10
Himanshu Bansal, Kristin Comella, Jerry Leon, Poonam Verma, Diwaker Agrawal, Prasad Koka, Thomas Ichim
BACKGROUND: Stromal vascular fraction (SVF) can easily be obtained from a mini-lipoaspirate procedure of fat tissue and platelet rich plasma (PRP) can be obtained from peripheral blood. We evaluated the safety and preliminary efficacy of administering SVF and PRP intra-articularly into patients with osteoarthritis grade 1 and 2. METHODS: A total of ten patients underwent a local tumescent liposuction procedure to remove approximately 100 ml of fat tissue from the abdomen...
June 19, 2017: Journal of Translational Medicine
https://www.readbyqxmd.com/read/28627466/patterns-of-intra-articular-injection-use-after-initiation-of-treatment-in-patients-with-knee-osteoarthritis-data-from-the-osteoarthritis-initiative
#11
Shao-Hsien Liu, Catherine E Dubé, Jeffrey B Driban, Timothy E McAlindon, Charles B Eaton, Kate L Lapane
OBJECTIVE: We sought to describe and evaluate longitudinal use of intra-articular injections after treatment initiation among adults with radiographically confirmed knee osteoarthritis (OA). METHOD: Using data from the Osteoarthritis Initiative, we included participants with radiographically confirmed OA (Kellgren-Lawrence grade (K-L) ≥ 2) in ≥ 1 knee at baseline. With 9 years of data, 412 participants newly initiating hyaluronic acid or corticosteroid injections with their index visit were identified...
June 13, 2017: Osteoarthritis and Cartilage
https://www.readbyqxmd.com/read/28626303/the-comparison-of-clinical-features-and-quality-of-life-after-total-knee-replacement
#12
Jiyeon Lee, Jung-Hee Kim, Eun-Jung Jung, Byoung-Hee Lee
[Purpose] The purpose of this study is to provide fundamental information for efficient management of patients after a total knee replacement (TKR) through the evaluation of changes of range of motion, pain, functional level, and quality of life. [Subjects and Methods] For a total of 63 knee osteoarthritis patients, VAS, KSKS, KSFS, HSS, WOMAC scores and quality of life were evaluated for functional levels at pre-operation, post-operation, six months after operation, and 12 months after operation. [Results] After the TKR operations, participants showed significant improvement in KSKS, KSFS, WOMAC, and SF-36 scores when compared to pre-operation...
June 2017: Journal of Physical Therapy Science
https://www.readbyqxmd.com/read/28624294/patient-decision-aids-for-patients-considering-total-joint-replacement-a-cost-effectiveness-analysis-alongside-a-randomised-controlled-trial-rct
#13
L Trenaman, D Stacey, S Bryan, M Taljaard, G Hawker, G Dervin, P Tugwell, N Bansback
BACKGROUND: Shared decision-making (SDM) is a key priority to improve patient-centred care, and can play an important role in helping patients decide whether to undergo total joint arthroplasty (TJA). Patient decision aids can support SDM; however, they may incur an upfront cost. We aimed to estimate the health and economic effects of patient decision aids for TJA. METHODS: A cost-effectiveness analysis of a randomised controlled trial (RCT) with 2-year follow-up...
June 15, 2017: Osteoarthritis and Cartilage
https://www.readbyqxmd.com/read/28623415/a-stand-alone-lateral-condyle-elevating-trochlear-osteotomy-leads-to-high-residual-instability-but-no-excessive-increase-in-patellofemoral-osteoarthritis-at-12-year-follow-up
#14
S Tigchelaar, J van Sambeeck, S Koeter, A van Kampen
PURPOSE AND HYPOTHESIS: Trochlear osteotomy is a rarely performed procedure, only indicated in selected cases. Due to its nature, it can potentially lead to cartilage damage and subsequent early osteoarthritis. Satisfactory short-term results from lateral condyle-elevating osteotomy have previously been reported. The long-term effects of this procedure on clinical outcomes, patellar stability and radiological osteoarthritis are reported here. METHODS: Sixteen patients (19 knees) with patellar instability due to trochlear dysplasia were included...
June 16, 2017: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/28614869/a-rosa-canina-urtica-dioica-harpagophytum-procumbens-zeyheri-combination-significantly-reduces-gonarthritis-symptoms-in-a-randomized-placebo-controlled-double-blind-study
#15
Margret Moré, Joerg Gruenwald, Ute Pohl, Ralf Uebelhack
The special formulation MA212 (Rosaxan) is composed of rosehip (Rosa canina L.) puree/juice concentrate, nettle (Urtica dioica L.) leaf extract, and devil's claw (Harpagophytum procumbens DC. ex Meisn. or Harpagophytum zeyheri Decne.) root extract and also supplies vitamin D. It is a food for special medical purposes ([EU] No 609/2013) for the dietary management of pain in patients with gonarthritis.This 12-week randomized, placebo-controlled double-blind parallel-design study aimed to investigate the efficacy and safety of MA212 versus placebo in patients with gonarthritis...
June 14, 2017: Planta Medica
https://www.readbyqxmd.com/read/28608254/determinants-of-physical-functioning-in-women-with-knee-osteoarthritis
#16
Hakan Nur, Bilge Saruhan Sertkaya, Tiraje Tuncer
BACKGROUND: Knee osteoarthritis (OA) is an important health problem with its high prevalence and association with pain and functional disability in physical tasks and activities especially in women. AIMS: To explore the impacts of widely seen demographic, pathological, psychological, and impairment factors on physical functioning in women with knee OA using the performance-based and self-reported measures. METHODS: One hundred and ten women with knee OA participated in this study...
June 12, 2017: Aging Clinical and Experimental Research
https://www.readbyqxmd.com/read/28605000/hip-arthroscopy-in-patients-less-than-25-years-of-age-in-the-treatment-of-labral-tears-aetiology-and-clinical-outcomes
#17
Gillian Bayley, Stephane Poitras, Gillian Parker, Paul E Beaulé
BACKGROUND: Hip arthroscopy has evolved into a well-established and rapidly growing field of orthopedic surgery for the management of labral tears. The purpose of this study was to review clinical outcomes of patients less than 25 years of age undergoing hip arthroscopy for treatment of a labral tear. METHODS: From 2005 to 2013, 82 hips in 76 patients with mean age of 20.4 (16-25 range) underwent hip arthroscopy for treatment of labral-chondral damage. The Western Ontario McMaster Universities Osteoarthritis Index (WOMAC) and hip disability and osteoarthritis outcome score (HOOS) were recorded at latest follow-up...
June 7, 2017: Hip International: the Journal of Clinical and Experimental Research on Hip Pathology and Therapy
https://www.readbyqxmd.com/read/28602782/associations-between-serum-ghrelin-and-knee-symptoms-joint-structures-and-cartilage-or-bone-biomarkers-in-patients-with-knee-osteoarthritis
#18
J Wu, K Wang, J Xu, G Ruan, Q Zhu, J Cai, J Ren, S Zheng, Z Zhu, P Otahal, C Ding
OBJECTIVE: The roles of ghrelin in knee osteoarthritis (OA) are unclear. This study aimed to examine cross-sectional associations of ghrelin with knee symptoms, joint structures and cartilage or bone biomarkers in patients with knee OA. METHODS: This study included 146 patients with symptomatic knee OA. Serum levels of ghrelin and cartilage or bone biomarkers including cartilage oligomeric matrix protein (COMP), cross linked C-telopeptide of type I collagen (CTXI), cross linked N-telopeptide of type I collagen (NTXI), N-terminal procollagen III propeptide (PIIINP), and matrix metalloproteinase (MMP)-3, 10, 13 were measured using Enzyme-linked immunosorbent assay (ELISA)...
June 15, 2017: Osteoarthritis and Cartilage
https://www.readbyqxmd.com/read/28593581/intraoperative-adjustment-of-alignment-under-valgus-stress-reduces-outliers-in-patients-undergoing-medial-opening-wedge-high-tibial-osteotomy
#19
Man Soo Kim, Jong Min Son, In Jun Koh, Ji Hoon Bahk, Yong In
INTRODUCTION: A considerable percentage of outliers with under- or over-correction continue to be reported despite precise preoperative planning and cautious intraoperative correction of lower limb alignment in medial opening-wedge high tibial osteotomy (MOWHTO). The purpose of this study was to determine whether our novel technique for the intraoperative adjustment of alignment under valgus stress reduces the number of outliers in patients undergoing MOWHTO compared to the conventional technique, which corrects alignment according to the cable method only...
June 7, 2017: Archives of Orthopaedic and Trauma Surgery
https://www.readbyqxmd.com/read/28592073/-influence-of-patellofemoral-joint-degeneration-on-outcome-of-medial-unicompartmental-knee-arthroplasty
#20
B Y Xu, B C Ji, W T Guo, W B Mu, L Cao
Objective: To evaluate the influence of patellofemoral joint degeneration and pre-operative pain location on the outcome of medial Oxford unicompartmental knee arthroplasty (UKA). Methods: A total of 58 patients (58 knees) with medial Oxford UKA had been performed for medial osteoarthritis from March 2013 to July 2014 in Department of Orthopaedic Surgery at First Teaching Hospital of Xinjiang Medical University were retrospective reviewed. There were 24 males and 34 females, the age from 43 to 87 years with the mean age was 68...
June 1, 2017: Zhonghua Wai Ke za Zhi [Chinese Journal of Surgery]
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