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https://www.readbyqxmd.com/read/29667132/obesity-and-episodic-memory-function
#1
REVIEW
Paul D Loprinzi, Emily Frith
Obesity-related lifestyle factors, such as physical activity behavior and dietary intake, have been shown to be associated with episodic memory function. From animal work, there is considerable biological plausibility linking obesity with worse memory function. There are no published systematic reviews evaluating the effects of obesity on episodic memory function among humans, and examining whether physical activity and diet influences this obesity-memory link. Thus, the purpose of this systematic review was to evaluate the totality of research examining whether obesity is associated with episodic memory function, and whether physical activity and dietary behavior confounds this relationship...
April 17, 2018: Journal of Physiological Sciences: JPS
https://www.readbyqxmd.com/read/29666045/general-practitioners-perspective-on-ehealth-and-lifestyle-change-qualitative-interview-study
#2
Carl Joakim Brandt, Gabrielle Isidora Søgaard, Jane Clemensen, Jens Sndergaard, Jesper Bo Nielsen
BACKGROUND: Wearables, fitness apps, and patient home monitoring devices are used increasingly by patients and other individuals with lifestyle challenges. All Danish general practitioners (GPs) use digital health records and electronic health (eHealth) consultations on a daily basis, but how they perceive the increasing demand for lifestyle advice and whether they see eHealth as part of their lifestyle support should be explored further. OBJECTIVE: This study aimed to explore GPs' perspectives on eHealth devices and apps and the use of eHealth in supporting healthy lifestyle behavior for their patients and themselves...
April 17, 2018: JMIR MHealth and UHealth
https://www.readbyqxmd.com/read/29664906/cigarette-smoking-is-a-risk-factor-for-the-onset-of-fatty-liver-disease-in-nondrinkers-a-longitudinal-cohort-study
#3
Masashi Okamoto, Teruki Miyake, Kohichiro Kitai, Shinya Furukawa, Shin Yamamoto, Hidenori Senba, Sayaka Kanzaki, Akiko Deguchi, Mitsuhito Koizumi, Toru Ishihara, Hiroaki Miyaoka, Osamu Yoshida, Masashi Hirooka, Teru Kumagi, Masanori Abe, Bunzo Matsuura, Yoichi Hiasa
BACKGROUND: The effect of cigarette smoking on the onset of nonalcoholic fatty liver disease (NAFLD) is unclear, especially that associated with drinking small amounts of alcohol. We conducted a longitudinal study to investigate the relationship between cigarette smoking and NAFLD onset, which was stratified according to the amount of alcohol consumed. METHODS: We enrolled 7,905 Japanese subjects who had received annual health checkups more than twice between April 2003 and August 2013, 4,045 of whom met at least one of the following exclusion criteria and were excluded: (a) fatty liver at baseline; (b) hepatitis B or hepatitis C; (c) alcohol consumption (men: ≥210 g/wk; women: ≥140 g/wk); (d) change in alcohol drinking status between baseline and the study's endpoint; (e) change in cigarette smoking habits between baseline and the study's endpoint; or (f) current treatment with antidiabetic agents, antihypertensive agents, and/or lipid-lowering agents...
2018: PloS One
https://www.readbyqxmd.com/read/29664564/immunological-memories-of-the-bone-marrow
#4
REVIEW
Hyun-Dong Chang, Koji Tokoyoda, Andreas Radbruch
Memory for antigens once encountered is a hallmark of the immune system of vertebrates, providing us with an immunity adapted to pathogens of our environment. Despite its fundamental relevance, the cells and genes representing immunological memory are still poorly understood. Here we discuss the concept of a circulating, proliferating, and ubiquitous population of effector lymphocytes vs concepts of resting and dormant populations of dedicated memory lymphocytes, distinct from effector lymphocytes and residing in defined tissues, particularly in barrier tissues and in the bone marrow...
May 2018: Immunological Reviews
https://www.readbyqxmd.com/read/29662650/hdl-and-associated-factors-stratified-by-sex-and-menopausal-status-results-from-a-community-based-survey-in-taiwan
#5
Huan-Cheng Chang, Chuan-Fa Hsieh, Disline Manli Tantoh, Pei-Chieh Ko, Ya-Yu Kung, Mei-Chi Lin, Yi-Ching Liaw, Yung-Po Liaw
Aim: To investigate factors, especially modifiable factors associated with high-density lipoprotein (HDL) in Taiwanese based on sex and menopausal status. Materials and Methods: Participants comprised 2022 men and 2392 women (1267 menopausal and 1125 non-menopausal) aged ≥30 years who resided in Pingzhen district, Taoyuan from 2006-2011. Their data, obtained through questionnaires and measurements were retrieved from the Li-Shin Hospital. Results: Higher HDL was associated with total cholesterol, underweight, and alcohol drinking in both men and women...
March 27, 2018: Oncotarget
https://www.readbyqxmd.com/read/29662261/prediabetes-in-colombia-expert-consensus
#6
REVIEW
Patricio López-Jaramillo, Carlos Calderón, Jorge Castillo, Iván Darío Escobar, Enrique Melgarejo, Gustavo Adolfo Parra
The prevalence of Prediabetes in Colombia is high, and despite being recognized and categorized in the main Medical Guidelines and included in the International Classification of Diseases in Colombia, knowledge and awareness of it is limited amongst healthcare professionals and in the community. Our expert group recommends that educational programs emphasize a global approach to risk which includes a recognition of the importance of prediabetes and its evaluation along with and other risk factors such as a family history of DM2, overweight and obesity, dislipidemia and hypertension...
December 30, 2017: Colombia Médica: CM
https://www.readbyqxmd.com/read/29661944/atrial-fibrillation-burden-moving-beyond-atrial-fibrillation-as-a-binary-entity-a-scientific-statement-from-the-american-heart-association
#7
REVIEW
Lin Y Chen, Mina K Chung, Larry A Allen, Michael Ezekowitz, Karen L Furie, Pamela McCabe, Peter A Noseworthy, Marco V Perez, Mintu P Turakhia
Our understanding of the risk factors and complications of atrial fibrillation (AF) is based mostly on studies that have evaluated AF in a binary fashion (present or absent) and have not investigated AF burden. This scientific statement discusses the published literature and knowledge gaps related to methods of defining and measuring AF burden, the relationship of AF burden to cardiovascular and neurological outcomes, and the effect of lifestyle and risk factor modification on AF burden. Many studies examine outcomes by AF burden classified by AF type (paroxysmal versus nonparoxysmal); however, quantitatively, AF burden can be defined by longest duration, number of AF episodes during a monitoring period, and the proportion of time an individual is in AF during a monitoring period (expressed as a percentage)...
April 16, 2018: Circulation
https://www.readbyqxmd.com/read/29661561/clinically-actionable-hypercholesterolemia-and-hypertriglyceridemia-in-children-with-nonalcoholic-fatty-liver-disease
#8
Kathryn E Harlow, Jonathan A Africa, Alan Wells, Patricia H Belt, Cynthia A Behling, Ajay K Jain, Jean P Molleston, Kimberly P Newton, Philip Rosenthal, Miriam B Vos, Stavra A Xanthakos, Joel E Lavine, Jeffrey B Schwimmer
OBJECTIVE: To determine the percentage of children with nonalcoholic fatty liver disease (NAFLD) in whom intervention for low-density lipoprotein cholesterol or triglycerides was indicated based on National Heart, Lung, and Blood Institute guidelines. STUDY DESIGN: This multicenter, longitudinal cohort study included children with NAFLD enrolled in the National Institute of Diabetes and Digestive and Kidney Diseases Nonalcoholic Steatohepatitis Clinical Research Network...
April 13, 2018: Journal of Pediatrics
https://www.readbyqxmd.com/read/29659918/association-of-dairy-intake-with-weight-change-in-adolescents-undergoing-obesity-treatment
#9
Brian H Wrotniak, Lesley Georger, Douglas L Hill, Babette S Zemel, Nicolas Stettler
Background: The role of dairy products in obesity treatment for adolescents is unclear. The study purpose was to assess the association between dairy intake and changes in BMI z-score (zBMI) during adolescent obesity treatment. Methods: Observational study nested within a randomized control trial. Linear mixed-effects regression models were adjusted for important non-lifestyle factors then further adjusted for dietary and physical activity variables. In total, 91 adolescents were studied...
April 5, 2018: Journal of Public Health
https://www.readbyqxmd.com/read/29659694/nutritional-genomics-and-direct-to-consumer-genetic-testing-an-overview
#10
Marta Guasch-Ferré, Hassan S Dashti, Jordi Merino
The increasing prevalence in polygenic diseases, such as obesity, cardiovascular disease, and type 2 diabetes, observed over the past few decades is more likely linked to a rapid transition in lifestyle rather than to changes in the sequence of the nuclear genome. In the new era of precision medicine, nutritional genomics holds the promise to be translated into tailored nutritional strategies to prevent and manage polygenic diseases more effectively. Nutritional genomics aims to prevent, treat, and manage polygenic diseases through targeted therapies formulated from individuals' genetic makeup and dietary intake...
March 1, 2018: Advances in Nutrition
https://www.readbyqxmd.com/read/29658287/perspectives-on-providing-and-receiving-preventive-health-care-from-primary-care-providers-and-their-patients-with-mental-illnesses
#11
Scott P Stumbo, Bobbi Jo H Yarborough, Micah T Yarborough, Carla A Green
PURPOSE: Individuals with mental illnesses have higher morbidity rates and reduced life expectancy compared to the general population. Understanding how patients and providers perceive the need for prevention, as well as the barriers and beliefs that may contribute to insufficient care, are important for improving service delivery tailored to this population. DESIGN: Cross-sectional; mixed methods. SETTING: An integrated health system and a network of federally qualified health centers and safety net clinics...
January 1, 2018: American Journal of Health Promotion: AJHP
https://www.readbyqxmd.com/read/29653359/the-role-of-the-gut-microbiota-in-the-pathology-and-prevention-of-liver-disease
#12
REVIEW
Alejandra Altamirano-Barrera, Misael Uribe, Norberto C Chávez-Tapia, Natalia Nuño-Lámbarri
Several microorganisms belonging to the intestinal microbiota act in an ecosystem responsible for maintaining the homeostasis and vital functions of human beings. From birth to old age the diversity of the intestinal microbiota may change due to environmental factors such as nutrition, immunity, diseases or the use of antibiotics leading to dysbiosis. Improvement in microbiota diversity can be achieved by modifying related risk factors through changes in lifestyle and a healthy diet. Besides, the addition of probiotics, prebiotics or the combination of both (symbiotics), can result in the improvement of the intestinal permeability, inflammatory pathways and the immune system...
March 16, 2018: Journal of Nutritional Biochemistry
https://www.readbyqxmd.com/read/29652666/effect-of-a-multidisciplinary-treatment-program-on-eating-behavior-in-overweight-and-obese-preschool-children
#13
Gianni Bocca, Mirije W B Kuitert, Pieter J J Sauer, Eva Corpeleijn
BACKGROUND: The effects of multidisciplinary treatment programs on eating behavior in overweight preschool-aged children are largely unknown. We evaluated a multidisciplinary intervention program on eating behavior in 3- to 5-year-old overweight children, comparing them with children given standard treatment. We also assessed the parental eating behavior changes and investigated associations between parents and children. METHODS: We randomized 75 children to a multidisciplinary intervention or to a standard care program...
April 13, 2018: Journal of Pediatric Endocrinology & Metabolism: JPEM
https://www.readbyqxmd.com/read/29652617/heart-checks-in-college-age-students-link-poor-sleep-to-cardiovascular-risk
#14
Kate Gawlik, Bernadette Mazurek Melnyk, Alai Tan, Megan Amaya
OBJECTIVE: To describe the relationships between the cardiovascular health, lifestyle behaviors, and lifestyle beliefs among college-age students. PARTICIPANTS: 729 college-aged students participated between October 2016 and April 2017. METHODS: Heart Checks, consisting of a cross-sectional survey and biometric screening, were conducted on a large Midwestern university campus. RESULTS: A small proportion of students (24...
April 13, 2018: Journal of American College Health: J of ACH
https://www.readbyqxmd.com/read/29651164/genome-wide-analysis-of-the-transition-to-pathogenic-lifestyles-in-magnaporthales-fungi
#15
Ning Zhang, Guohong Cai, Dana C Price, Jo Anne Crouch, Pierre Gladieux, Bradley Hillman, Chang Hyun Khang, Marc-Henri LeBrun, Yong-Hwan Lee, Jing Luo, Huan Qiu, Daniel Veltri, Jennifer H Wisecaver, Jie Zhu, Debashish Bhattacharya
The rice blast fungus Pyricularia oryzae (syn. Magnaporthe oryzae, Magnaporthe grisea), a member of the order Magnaporthales in the class Sordariomycetes, is an important plant pathogen and a model species for studying pathogen infection and plant-fungal interaction. In this study, we generated genome sequence data from five additional Magnaporthales fungi including non-pathogenic species, and performed comparative genome analysis of a total of 13 fungal species in the class Sordariomycetes to understand the evolutionary history of the Magnaporthales and of fungal pathogenesis...
April 12, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29650407/chronic-obstructive-pulmonary-disease-in-china-a-nationwide-prevalence-study
#16
Liwen Fang, Pei Gao, Heling Bao, Xun Tang, Baohua Wang, Yajing Feng, Shu Cong, Juan Juan, Jing Fan, Ke Lu, Ning Wang, Yonghua Hu, Linhong Wang
BACKGROUND: Because of the rapid change in economic development and lifestyle in China, and the ageing population, concerns have grown that chronic obstructive pulmonary disease (COPD) could become epidemic. An up-to-date nationwide estimation of COPD prevalence in China is needed. METHODS: We did a cross-sectional survey of a nationally representative sample of individuals from mainland China aged 40 years or older. The primary outcome was COPD, defined according to the 2017 Global Initiative for Chronic Obstructive Lung Disease (GOLD) lung function criteria...
April 9, 2018: Lancet Respiratory Medicine
https://www.readbyqxmd.com/read/29649377/vitamin-d-status-and-cardiovascular-risk-in-obesity-effect-of-physical-activity-in-nonvitamin-d-supplemented-adolescents
#17
Md Jobayer Hossain, Alexa Levinson, Donald George, Jose Canas, Seema Kumar, P Babu Balagopal
BACKGROUND: The relationship among inadequate vitamin D status, obesity, and cardiometabolic risk and the potential impact of physical activity-based interventions on vitamin D status are poorly characterized in children. This study aimed to address these issues. METHODS: We studied a total of 21 adolescents (15 obese and 6 normal weight; age: 14-18 years; Tanner stage>IV). Adolescents with obesity (n = 15) underwent a randomized controlled (8 in the intervention group and 7 in the control group) 3-month physical activity-based lifestyle intervention...
March 13, 2018: Metabolic Syndrome and related Disorders
https://www.readbyqxmd.com/read/29649106/mosh-syndrome-male-obesity-secondary-hypogonadism-clinical-assessment-and-possible-therapeutic-approaches
#18
Antonino De Lorenzo, Annalisa Noce, Eleonora Moriconi, Tiziana Rampello, Giulia Marrone, Nicola Di Daniele, Valentina Rovella
Male obesity secondary hypogonadism (MOSH) impairs fertility, sexual function, bone mineralization, fat metabolism, cognitive function, deteriorates muscle mass and alters body composition. The aim of this pilot study was to evaluate the effect of dietary intervention and physical activity on the MOSH patient's hormonal profile after a 10% weight loss compared to baseline. Fourteen male patients were enrolled. Hormonal, lipid, glycemic profiles and body composition were determined at baseline and after a 10% weight loss...
April 12, 2018: Nutrients
https://www.readbyqxmd.com/read/29649087/activity-of-daily-living-after-long-level-fusion-in-adult-spinal-deformity-compared-with-over-60-years-old-degenerative-spine-patients-without-adult-spinal-deformity
#19
Whoan Jeang Kim, Jae Won Lee, Seok Young Hwang, Kun Young Park, Shann Haw Chang, Dae Geon Song, Won Sik Choy
STUDY DESIGN: Prospective single center study. OBJECTIVE: The aim of this study was to evaluate 1) the activity of daily living (ADL) of three categorized patients group; over sixty-year old degenerative spine patients without adult spinal deformity (ASD), non-operative ASD patients, and operative ASD patients, 2) what kinds of activities would be impaired, and 3) how the ADL changes over time after long level fusion. SUMMARY OF BACKGROUND DATA: There is still debate how surgeons could decide treatment methods for old aged adult spinal deformity, operatively or not...
April 11, 2018: Spine
https://www.readbyqxmd.com/read/29648899/role-of-hoxc-genes-in-the-development-of-the-limb-integumentary-organ-nail-claw-or-hoof
#20
Maria Angeles Ros Lasierra, Marc Fernández-Guerrero, Lucille Delisle, Nayuta Yakushiji-Kaminatsui, Fabrice Darbellay, Rocío Pérez-Gómez, Denis Duboule
The developing vertebrate limb has long proved as an excellent system for studying the mechanisms involved in pattern formation and morphogenesis and more recently in transcriptional regulation and morphological evolution. To elucidate the stage-specific expression profiles of the components of the developing limb, we have generated the temporal transcriptome of the limb progenitors and of the overlying ectoderm separately. Our study has uncovered a collinear activation of Hoxc genes in the limb ectoderm that we have validated by in situ hybridization...
April 2018: FASEB Journal: Official Publication of the Federation of American Societies for Experimental Biology
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