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https://www.readbyqxmd.com/read/29471444/relation-of-sex-hormone-levels-with-prevalent-and-10-year-change-in-aortic-distensibility-assessed-by-mri-the-multi-ethnic-study-of-atherosclerosis
#1
V Subramanya, B Ambale-Venkatesh, Y Ohyama, D Zhao, C C Nwabuo, W S Post, E Guallar, P Ouyang, S J Shah, M A Allison, C E Ndumele, D Vaidya, D A Bluemke, J A Lima, E D Michos
Background: Women experience a steeper decline in aortic elasticity related to aging compared to men. We examined whether sex hormone levels were associated with ascending aortic distensibility (AAD) in the Multi-Ethnic Study of Atherosclerosis. Methods: We studied 1,345 post-menopausal women and 1,532 men aged 45-84 years, who had serum sex hormone levels, AAD measured by phase-contrast cardiac magnetic resonance imaging, and ejection fraction>50% at baseline...
February 19, 2018: American Journal of Hypertension
https://www.readbyqxmd.com/read/29471232/changes-in-pro-inflammatory-cytokine-levels-and-late-life-depression-a-two-year-population-based-longitudinal-study
#2
Jae-Min Kim, Robert Stewart, Ju-Wan Kim, Hee-Ju Kang, Kyung-Yeol Bae, Sung-Wan Kim, Il-Seon Shin, Jin-Sang Yoon
Longitudinal associations of cytokine levels with depression are unclear. This study aimed to investigate cross-sectional and prospective associations between five serum pro-inflammatory cytokine levels and late-life depression. 732 Korean people aged 65+ were evaluated at baseline. Of 631 without depression (Geriatric Mental State schedule) at baseline, 521 (83%) were followed over a 2 year period and incident depression was ascertained. Serum tumor necrosis factor-α, interleukin (IL)-1α, IL-1β, IL-6, and IL-8 levels were assayed at both baseline and follow-up...
February 14, 2018: Psychoneuroendocrinology
https://www.readbyqxmd.com/read/29471161/peripheral-artery-disease-and-antiplatelet-treatment
#3
REVIEW
Vasiliki Tsigkou, Gerasimos Siasos, Kleanthis Rovos, Niki Tripyla, Dimitris Tousoulis
Peripheral artery disease (PAD) is one of the most important causes of cardiovascular morbidity and mortality and its prevalence is alarmingly increasing in modern societies. PAD shares common characteristics with the other atherosclerotic diseases but involves specifically the arteries of the lower extremities. Apart from the changes in lifestyle, antiplatelet agents are the hallmark of the treatment and improve the symptoms as well as the progression of the disease. Aspirin is the cornerstone of treatment and is administrated in doses ranging from 75 to 325mg daily...
February 19, 2018: Current Opinion in Pharmacology
https://www.readbyqxmd.com/read/29471100/dynamic-fmri-networks-predict-success-in-a-behavioral-weight-loss-program-among-older-adults
#4
Fatemeh Mokhtari, W Jack Rejeski, Yingying Zhu, Guorong Wu, Sean L Simpson, Jonathan H Burdette, Paul J Laurienti
More than one-third of adults in the United States are obese, with a higher prevalence among older adults. Obesity among older adults is a major cause of physical dysfunction, hypertension, diabetes, and coronary heart diseases. Many people who engage in lifestyle weight loss interventions fail to reach targeted goals for weight loss, and most will regain what was lost within 1-2 years following cessation of treatment. This variability in treatment efficacy suggests that there are important phenotypes predictive of success with intentional weight loss that could lead to tailored treatment regimen, an idea that is consistent with the concept of precision-based medicine...
February 19, 2018: NeuroImage
https://www.readbyqxmd.com/read/29470459/prevalence-of-self-reported-hypertension-and-antihypertensive-medication-use-among-adults-aged-%C3%A2-18-years-united-states-2011-2015
#5
Jing Fang, Cathleen Gillespie, Carma Ayala, Fleetwood Loustalot
Hypertension, which affects nearly one third of adults in the United States, is a major risk factor for heart disease and stroke (1), and only approximately half of those with hypertension have their hypertension under control (2). The prevalence of hypertension is highest among non-Hispanic blacks, whereas the prevalence of antihypertensive medication use is lowest among Hispanics (1). Geographic variations have also been identified: a recent report indicated that the Southern region of the United States had the highest prevalence of hypertension as well as the highest prevalence of medication use (3)...
February 23, 2018: MMWR. Morbidity and Mortality Weekly Report
https://www.readbyqxmd.com/read/29468749/the-effect-of-pre-pregnancy-lifestyle-counselling-on-food-intakes-and-association-between-food-intakes-and-gestational-diabetes-in-high-risk-women-results-from-a-randomised-controlled-trial
#6
A J Valkama, J Meinilä, S Koivusalo, J Lindström, K Rönö, B Stach-Lempinen, H Kautiainen, J G Eriksson
BACKGROUND: Healthy diets before and during pregnancy have been suggested to reduce the risk of gestational diabetes (GDM). Several lifestyle intervention studies for pregnant women have reported dietary improvements after counselling. However, evidence concerning the effect of counselling initiated before pregnancy on diets is limited. METHODS: This randomised controlled study explored whether pre-pregnancy lifestyle counselling influenced food intakes, as well as whether changes in food intakes were associated with GDM...
February 22, 2018: Journal of Human Nutrition and Dietetics: the Official Journal of the British Dietetic Association
https://www.readbyqxmd.com/read/29467561/development-of-a-participatory-capacity-building-program-for-congregational-health-leaders-in-african-american-churches-in-the-us-south
#7
Mercedes M Morales-Alemán, Artisha Moore, Isabel C Scarinci
African Americans are disproportionately affected by diabetes and colorectal cancer. Although studies have shown the effectiveness of spiritually based health interventions delivered by community health workers to African Americans, few have described the development of the capacity-building component. This article describes this process. The development of the Healthy Congregations Healthy Communities Program (HCHC) was guided through a community-based participatory research lens and included: 1) establishment of a community coalition; 2) identification by coalition members of churches as the best venues for health promotion strategies among African Americans; 3) recruitment of churches; 4) development of a training manual; 5) recruitment and training of congregational health leaders (CHLs); and 6) "Passing of the torch" from the coalition to the CHLs who implemented the intervention in their congregations...
2018: Ethnicity & Disease
https://www.readbyqxmd.com/read/29466492/urbanization-is-associated-with-increased-trends-in-cardiovascular-mortality-among-indigenous-populations-the-pai-study
#8
Anderson da Costa Armstrong, Ana Marice Teixeira Ladeia, Juracy Marques, Dinani Matoso Fialho de Oliveira Armstrong, Antonio Marconi Leandro da Silva, Jeová Cordeiro de Morais Junior, Aldina Barral, Luis Claudio Lemos Correia, Manoel Barral-Netto, João A C Lima
BACKGROUND: The cardiovascular risk burden among diverse indigenous populations is not totally known and may be influenced by lifestyle changes related to the urbanization process. OBJECTIVES: To investigate the cardiovascular (CV) mortality profile of indigenous populations during a rapid urbanization process largely influenced by governmental infrastructure interventions in Northeast Brazil. METHODS: We assessed the mortality of indigenous populations (≥ 30 y/o) from 2007 to 2011 in Northeast Brazil (Bahia and Pernambuco states)...
February 19, 2018: Arquivos Brasileiros de Cardiologia
https://www.readbyqxmd.com/read/29465812/the-role-of-salt-for-immune-cell-function-and-disease
#9
REVIEW
Ralf Willebrand, Markus Kleinewietfeld
The immune system evolved to protect organisms from invading pathogens. A network of pro- and anti-inflammatory cell types equipped with special effector molecules guarantees efficient elimination of intruders like viruses and bacteria. However, imbalances can lead to an exceeding response of effector cells incurring autoimmune or allergic diseases. An interplay of genetic and environmental factors contributes to autoimmune diseases and recent studies provided evidence for an impact of dietary habits on the immune status and related disorders...
February 21, 2018: Immunology
https://www.readbyqxmd.com/read/29465154/implications-of-modified-food-choices-and-food-related-lifestyles-following-the-economic-crisis-in-the-marche-region-of-italy
#10
S Scuri, M Tesauro, F Petrelli, A Peroni, L Kracmarova, I Grappasonni
BACKGROUND: The economic crisis in Italy has led to profound changes in resource management not only at the macro level but also for individual families, causing substantial changes in different habits of Italians. STUDY DESIGN: The purpose of this research was to conduct a study on changes in family eating habits potentially triggered by the economic crisis was conducted in an area of the Marche Region in central Italy. METHODS: The research was conducted in the period 2016 - 2017 by administering a specific and anonymous questionnaire...
March 2018: Annali di Igiene: Medicina Preventiva e di Comunità
https://www.readbyqxmd.com/read/29464967/the-familias-saludables-partnership-engaging-the-latino-community-to-address-early-childhood-obesity
#11
Darcy A Thompson, Deborah A Federspiel
Darcy A Thompson is an Associate Professor of pediatrics at the University of Colorado School of Medicine. Her main research seeks to address early childhood obesity in low-income children. She works in the Lifestyle Medicine clinic at Children's Hospital Colorado, a clinic focused on caring for children with obesity and related comorbidities. She is also an Associate Medical Director for the Research Institute at Children's Hospital Colorado. Her training includes a Master of Public Health degree, a medical degree (Yale University) and the Robert Wood Johnson Clinical Scholars Fellowship (University of Washington)...
February 21, 2018: Journal of Comparative Effectiveness Research
https://www.readbyqxmd.com/read/29463591/optimising-gestational-weight-gain-and-improving-maternal-and-infant-health-outcomes-through-antenatal-dietary-lifestyle-and-physical-activity-advice-the-optimise-randomised-controlled-trial-protocol
#12
Jodie M Dodd, Andrea R Deussen, Jennie Louise
INTRODUCTION: Obesity represents a significant health burden, and WHO recognises the importance of preventing weight gain and subsequent development of obesity among adults who are within the healthy weight range. Women of reproductive age have demonstrated high rates of weight gain during pregnancy placing them at risk of becoming overweight or obese. We will evaluate the effects of dietary and physical activity advice on maternal, fetal and infant health outcomes, among pregnant women of normal body mass index (BMI)...
February 20, 2018: BMJ Open
https://www.readbyqxmd.com/read/29463491/a-smartphone-app-to-promote-an-active-lifestyle-in-lower-educated-working-young-adults-development-usability-acceptability-and-feasibility-study
#13
Dorien Simons, Ilse De Bourdeaudhuij, Peter Clarys, Katrien De Cocker, Corneel Vandelanotte, Benedicte Deforche
BACKGROUND: Physical activity (PA) levels are problematic in lower-educated working young adults (18-26 years). To promote PA, smartphone apps have great potential, but there is no evidence for their effectiveness in this population. To increase the likelihood that a newly developed app will be effective, formative research and user testing are required. OBJECTIVE: The aim of this study was to describe the development, usability, acceptability, and feasibility of a new theory- and evidence-based smartphone app to promote an active lifestyle in lower-educated working young adults...
February 20, 2018: JMIR MHealth and UHealth
https://www.readbyqxmd.com/read/29463050/associations-between-ambient-particulate-matter-and-nitrogen-dioxide-and-chronic-obstructive-pulmonary-diseases-in-adults-and-effect-modification-by-demographic-and-lifestyle-factors
#14
Dirga Kumar Lamichhane, Jong Han Leem, Hwan Cheol Kim
This study was undertaken to investigate the associations between chronic exposure to particulate matter of medium aerodynamic diameter ≤10 or ≤2.5 µm (PM10 or PM2.5 ) and nitrogen dioxide (NO₂) levels and lung function and to examine a possible change in these relationships by demographic and lifestyle factors. Chronic obstructive pulmonary disease (COPD) was defined using the Global Initiative for COPD criteria (forced expiratory volume in 1 second (FEV1)/forced vital capacity (FVC) of <70%). Associations of lung function and COPD with PM10 or PM2...
February 19, 2018: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/29461580/-p-ethnic-and-cultural-aspects-of-type-2-diabetes-p
#15
Louise Bennet
Political instability the last decades has forced millions of people to migrate from their homelands. In Sweden today, 1.6 million are born abroad, of which the largest immigrant groups originate from the Middle East. Immigrants from these areas represent high risk populations for type 2 diabetes with prevalence of type 2 diabetes twice as high compared to the native Swedish population. The mechanisms behind this increased diabetes risk are not fully unraveled but are likely connected to lifestyle, socioeconomic situation, genetics and epigenetics...
February 20, 2018: Läkartidningen
https://www.readbyqxmd.com/read/29461230/-clinical-and-psychological-correlations-in-fibromyalgia-patients
#16
G Suleymanova, R Grekhov, I Zborovskaya
The features of clinical symptoms, neurotic disorders and the level of subjective control were studied in patients with fibromyalgia. The analysis of relationship between the level of subjective control and neurotic symptoms (asthenia, depression, anxiety, hypochondria) depending the severity of main clinical manifestations of the disease was carried out. It was found that high intensity of fatigue, muscle pain, stiffness, insomnia, and an increase in the number of diagnostic tender points contribute to the formation of inverse correlation between the level of subjective control and neurotic disturbances...
January 2018: Georgian Medical News
https://www.readbyqxmd.com/read/29460649/identification-of-potential-lifestyle-responsive-epigenomic-biomarkers-in-healthy-women-aged-18-40
#17
Michelle Thunders, Victoria Chinn, Jaret Bilewitch, Peter Stockwell
CONTEXT: Human health is complex and multifaceted; there is a need for biomarkers that reflect the multidimensional nature of health. OBJECTIVE: To identify potential epigenomic biomarkers of health in women aged 18-40 participating in a 6 month lifestyle intervention, Next Level Health. MATERIALS AND METHODS: Methylation data were obtained by Reduced Representation Bisulfite Sequencing of 21 women intervention participants as well as 3 non-participants...
February 20, 2018: Biomarkers: Biochemical Indicators of Exposure, Response, and Susceptibility to Chemicals
https://www.readbyqxmd.com/read/29459102/older-age-early-symptoms-and-physical-function-are-associated-with-the-severity-of-late-symptom-clusters-for-men-undergoing-radiotherapy-for-prostate-cancer
#18
A Lemanska, D P Dearnaley, R Jena, M R Sydes, S Faithfull
AIMS: To identify symptom clusters and predisposing factors associated with long-term symptoms and health-related quality of life after radiotherapy in men with prostate cancer. MATERIALS AND METHODS: Patient-reported outcomes (PROs) data from the Medical Research Council RT01 radiotherapy with neoadjuvant androgen deprivation therapy trial of 843 patients were used. PROs were collected over 5 years with the University of California, Los Angeles Prostate Cancer Index (UCLA-PCI) and the 36 item Short-Form Health Survey (SF-36)...
February 16, 2018: Clinical Oncology: a Journal of the Royal College of Radiologists
https://www.readbyqxmd.com/read/29458656/stress-responses-outer-membrane-permeability-control-and-antimicrobial-resistance-in-enterobacteriaceae
#19
Sushovan Dam, Jean-Marie Pagès, Muriel Masi
Bacteria have evolved several strategies to survive a myriad of harmful conditions in the environment and in hosts. In Gram-negative bacteria, responses to nutrient limitation, oxidative or nitrosative stress, envelope stress, exposure to antimicrobials and other growth-limiting stresses have been linked to the development of antimicrobial resistance. This results from the activation of protective changes to cell physiology (decreased outer membrane permeability), resistance transporters (drug efflux pumps), resistant lifestyles (biofilms, persistence) and/or resistance mutations (target mutations, production of antibiotic modification/degradation enzymes)...
January 25, 2018: Microbiology
https://www.readbyqxmd.com/read/29458348/patients-and-caregivers-experiences-of-using-continuous-glucose-monitoring-to-support-diabetes-self-management-qualitative-study
#20
J Lawton, M Blackburn, J Allen, F Campbell, D Elleri, L Leelarathna, D Rankin, M Tauschmann, H Thabit, R Hovorka
BACKGROUND: Continuous glucose monitoring (CGM) enables users to view real-time interstitial glucose readings and provides information on the direction and rate of change of blood glucose levels. Users can also access historical data to inform treatment decisions. While the clinical and psychological benefits of CGM are well established, little is known about how individuals use CGM to inform diabetes self-management. We explored participants' experiences of using CGM in order to provide recommendations for supporting individuals to make optimal use of this technology...
February 20, 2018: BMC Endocrine Disorders
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