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https://www.readbyqxmd.com/read/29912419/-i-m-not-a-real-boozer-a-qualitative-study-of-primary-care-patients-views-on-drinking-and-its-consequences
#1
Z Khadjesari, F Stevenson, P Toner, S Linke, J Milward, E Murray
Background: The public health message around alcohol is complex, with benefits versus harms, the confusing concept of risk and drinking guidance changing over time. This provides a difficult context for alcohol screening in primary care, with established barriers from the practitioner perspective, but less is known about the patients' perspective. This study explores patients' views on drinking. Methods: Eligible participants were recorded as drinking above low risk levels in primary care...
April 18, 2018: Journal of Public Health
https://www.readbyqxmd.com/read/29911873/differential-5-year-brain-atrophy-rates-in-cognitively-declining-and-stable-apoe-%C3%AE%C2%B54-elders
#2
Dana A Kelly, Michael Seidenberg, Katherine Reiter, Kristy A Nielson, John L Woodard, J Carson Smith, Sally Durgerian, Stephen M Rao
OBJECTIVE: The apolipoprotein E (APOE) ε4 allele is the most important genetic risk factor for late-onset Alzheimer's disease. Many ε4 carriers, however, never develop Alzheimer's disease. The purpose of this study is to characterize the variability in phenotypic expression of the ε4 allele, as measured by the longitudinal trajectory of cognitive test scores and MRI brain volumes, in cognitively intact elders. METHOD: Healthy older adults, ages 65-85, participated in a 5-year longitudinal study that included structural MRI and cognitive testing administered at baseline and at 1...
June 18, 2018: Neuropsychology
https://www.readbyqxmd.com/read/29910850/role-of-gut-microbiota-in-the-pathogenesis-of-colorectal-cancer-a-review-article
#3
REVIEW
Somayeh Jahani-Sherafat, Masoud Alebouyeh, Sharareh Moghim, Hamed Ahmadi Amoli, Hajieh Ghasemian-Safaei
Colorectal cancer (CRC) is one of the most frequently diagnosed cancers worldwide. Lifestyle is identified as one of the most important risk factors for CRC, especially in sporadic colorectal cancer. The natural composition of the gut microbiota changes rapidly during the first decade of life. Maintaining homeostasis in the gut is essential as structural and metabolic functions of the commensal microbiota inhibit gut colonization of pathogens. Dysbiosis, imbalance in function or structure of gut microbiota, has been associated with a variety of diseases, such as colorectal cancer...
2018: Gastroenterology and Hepatology From Bed to Bench
https://www.readbyqxmd.com/read/29910462/the-rise-and-rise-of-eosinophilic-gut-diseases-including-eosinophilic-esophagitis-is-probably-not-explained-by-the-disappearance-of-helicobacter-pylori-so-who-or-what-s-to-blame
#4
EDITORIAL
Nicholas J Talley, Marjorie M Walker
A dramatic increase in eosinophilic esophagitis (EoE) and atopic disease and a dramatic decline in Helicobacter pylori infection has been observed in the last few decades. Previously, it was speculated that the immune response to H. pylori may protect against allergic diseases including EoE, but this study by Molina-Infante et al. shows no clear relationship, and suggests that any correlation is not causal. In truth it is likely that a combination of many factors, including a changing microbiome with increasing hygiene and alterations in early life such as antibiotic exposure, changing diet and other lifestyle factors drive increasing atopic diseases including food allergies and EoE...
June 18, 2018: American Journal of Gastroenterology
https://www.readbyqxmd.com/read/29910418/are-we-compensating-for-the-lack-of-physical-activity-in-our-diabetic-patients-with-treatment-intensification
#5
Maja Cigrovski Maja Cigrovski Berkovic, Ines Bilic-Curcic, Marina Gradiser, Davorka Herman-Mahecic, Vjekoslav Cigrovski, Marul Ivandic
BACKGROUND: We studied the association between leisure time physical activity (LTPA) and glycemic control, body mass index (BMI), and hypoglycemic incidents in type 1 (T1DM) and type 2 diabetes patients (T2DM). METHODS: This is a cross-sectional study of 198 diabetic patients (60 with type 1 diabetes, 138 with type 2 diabetes). LTPA was assessed by a validated 12-month questionnaire. Patients were grouped as sedentary and moderately to vigorously active. Outcome measures were Hemoglobin A1c (HbA1c), BMI, and hypoglycemic episodes...
August 7, 2017: Sports (Basel)
https://www.readbyqxmd.com/read/29910412/effect-of-yang-style-tai-chi-on-gait-parameters-and-musculoskeletal-flexibility-in-healthy-chinese-older-women
#6
Liye Zou, Chaoyi Wang, Zuguo Tian, Huiru Wang, Yankai Shu
The purpose of the present study was to examine the effect of Yang-style Tai chi (TC) on gait parameters and musculoskeletal flexibility in healthy Chinese female adults. Sixty-six female adults aged >65 years were randomly assigned to either an experimental group (67.9 ± 3.2 years of age) receiving three 90-min simplified 24-form TC sessions for eight weeks, or a control group (67.4 ± 2.9 years of age) who maintained their daily lifestyles. All study participants were instructed to perform a selected pace walking for recording gait parameters (stride length, gait speed, swing cycle time, stance phase, and double support times) at both baseline and after the experiment...
July 17, 2017: Sports (Basel)
https://www.readbyqxmd.com/read/29910143/exploring-public-views-on-marine-litter-in-europe-perceived-causes-consequences-and-pathways-to-change
#7
Bonny L Hartley, Sabine Pahl, Joana Veiga, Thomais Vlachogianni, Lia Vasconcelos, Thomas Maes, Tom Doyle, Ryan d'Arcy Metcalfe, Ayaka Amaha Öztürk, Mara Di Berardo, Richard C Thompson
Marine litter is a global challenge and society plays an important role via lifestyles and behaviour, including policy support. We analysed public perceptions of marine litter and contributing factors, using data from 1133 respondents across 16 European countries. People reported high levels of concern about marine litter, and the vast majority (95%) reported seeing litter when visiting the coast. The problem was attributed to product and packaging design and behaviour rather than lack of facilities or accidental loss of items...
June 13, 2018: Marine Pollution Bulletin
https://www.readbyqxmd.com/read/29908771/cognitive-behavioral-therapy-improves-weight-loss-and-quality-of-life-in-women-with-polycystic-ovary-syndrome-a-pilot-randomized-clinical-trial
#8
Laura G Cooney, Lauren W Milman, Liisa Hantsoo, Sara Kornfield, Mary D Sammel, Kelly C Allison, C Neill Epperson, Anuja Dokras
OBJECTIVE: To compare the effects of cognitive-behavioral therapy (CBT) and lifestyle modification (LS) versus LS alone on weight, depressive and anxiety symptoms, and stress response in women with polycystic ovary syndrome (PCOS), overweight/obesity, and depressive symptoms. DESIGN: A 16-week pilot randomized clinical trial. SETTING: Tertiary-care PCOS center. PATIENT(S): Overweight/obese women with PCOS and depressive symptoms...
June 13, 2018: Fertility and Sterility
https://www.readbyqxmd.com/read/29908726/digital-health-intervention-as-an-adjunct-to-a-workplace-health-program-in-hypertension
#9
Conor Senecal, R Jay Widmer, Matthew P Johnson, Lilach O Lerman, Amir Lerman
BACKGROUND: Hypertension is a common and difficult-to-treat condition; digital health tools may serve as adjuncts to traditional pharmaceutical and lifestyle-based interventions. Using a retrospective observational study we sought to evaluate the effect of a desktop and mobile digital health intervention (DHI) as an adjunct to a workplace health program in those previously diagnosed with hypertension. METHODS: As part of a workplace health program, 3330 patients were identified as previously diagnosed with hypertension...
May 30, 2018: Journal of the American Society of Hypertension: JASH
https://www.readbyqxmd.com/read/29907557/effective-behavioral-changes-through-a-digital-mhealth-app-exploring-the-impact-of-hedonic-well-being-psychological-empowerment-and-inspiration
#10
Yuting Lin, Carina Tudor-Sfetea, Sarim Siddiqui, Yusuf Sherwani, Maroof Ahmed, Andreas B Eisingerich
BACKGROUND: New mobile health (mHealth) software apps are emerging and are providing the foundation to radically transform the practice and reach of medical research and care. For this study we collaborated with Quit Genius, a cognitive behavioral therapy (CBT) based mHealth app that helps users quit smoking, to explore the effective design of a digital mHealth app; one that delivers important benefits to its users and helps them change their behaviors for a healthier lifestyle. OBJECTIVE: The specific aims of this study were to (1) explore the key role of CBT program progress, (2) examine the gamification design app elements that deliver significant benefits (ie, empowerment, well-being, inspiration) to users, (3) explore the effectiveness of these app elements to help users quit smoking or reduce the number of cigarettes smoked, and (4) identify and describe any potential drivers and hindrances arising from the app design elements...
June 15, 2018: JMIR MHealth and UHealth
https://www.readbyqxmd.com/read/29907545/differential-proteome-analysis-of-diabetes-mellitus-type-2-and-its-pathophysiological-complications
#11
REVIEW
Waleed Sohail, Fatimah Majeed, Amber Afroz
The prevalence of Diabetes Mellitus Type 2 (DM 2) is increasing every passing year due to some global changes in lifestyles of people. The exact underlying mechanisms of the progression of this disease are not yet known. However recent advances in the combined omics more particularly in proteomics and genomics have opened a gateway towards the understanding of predetermined genetic factors, progression, complications and treatment of this disease. Here we shall review the recent advances in proteomics that have led to an early and better diagnostic approaches in controlling DM 2 more importantly the comparison of structural and functional protein biomarkers that are modified in the diseased state...
June 11, 2018: Diabetes & Metabolic Syndrome
https://www.readbyqxmd.com/read/29907115/determinants-of-human-papillomavirus-vaccine-attitudes-an-interview-of-wisconsin-parents
#12
Kathrine L Barnes, Jeffrey J VanWormer, Shannon Stokley, Elizabeth R Vickers, Huong Q McLean, Edward A Belongia, Casper G Bendixsen
BACKGROUND: Parental attitudes play a key role in their decisions to vaccinate adolescents against the human papillomavirus (HPV). Little is known, however, about the formative experiences that shape parents' attitudes about the HPV vaccine. METHODS: We conducted semi-structured interviews with 25 parents of 11-17 year old adolescents in Wisconsin who changed their HPV vaccine attitudes (per prior surveys) over one year. A modified grounded theory approach was then used to generate primary themes of attitudinal determinants...
June 15, 2018: BMC Public Health
https://www.readbyqxmd.com/read/29905590/are-college-students-told-by-health-care-providers-about-their-risk-factors-for-developing-diabetes
#13
Jennifer L Saylor, Christina J Calamaro, Thomas Hardie, Michelle Ness, Janice Selekman
BACKGROUND AND PURPOSE: Communication about risk factors for diabetes between nurse practitioners and college students may not be occurring as the prevalence of Type 2 diabetes increases. The purpose of this secondary analysis was to evaluate if college students are being told of their risk for diabetes based on known risk factors of weight, sleep, and depressive symptoms. METHODS: Descriptive, cross-sectional study was completed using National Health and Nutrition Examination Survey 2011-2012...
June 4, 2018: Journal of the American Association of Nurse Practitioners
https://www.readbyqxmd.com/read/29905499/developing-nurses-skills-in-motivational-interviewing-to-promote-a-healthy-lifestyle-in-patients-with-coronary-artery-disease
#14
Jos Dobber, Corine Latour, Marjolein Snaterse, Berno van Meijel, Gerben Ter Riet, Wilma Scholte Op Reimer, Ron Peters
BACKGROUND: If nurses have the communication skills and the time, they can play an important role in increasing the intrinsic motivation of patients with coronary artery disease (CAD) to change their lifestyle. Motivational Interviewing (Mo-Int) can be used to further support this role. However, few nurses are sufficiently proficient in applying Mo-Int skills. Increasing these complex communication skills may contribute significantly to achieve lifestyle changes in CAD patients. AIMS: The aim of this study was to evaluate the coaching of nurses to skilfully use Mo-Int in a secondary prevention programme for CAD patients...
June 1, 2018: European Journal of Cardiovascular Nursing
https://www.readbyqxmd.com/read/29902941/accessibility-information-in-new-delhi-for-easenaccess-android-based-app-for-persons-with-disability-an-observational-study
#15
Yashovardhan Agarwal
BACKGROUND: The World Health Organization and the World Bank's "World Report on Disability" reported that over 1 billion people have various kinds of disability worldwide while Indian Census 2011 reported about 26 million in India. The United Nations Convention states, "The Rights of Persons with Disabilities (PwD) include accessibility to Information, Transportation, Environment, Communication Technology and Services". OBJECTIVE: This article takes forward the reason of making the "EasenAccess" (EnA) Android-based app to empower PwD with wheelchair-accessibility information, communication sentences and sending SOS signals with location...
June 14, 2018: Disability and Rehabilitation. Assistive Technology
https://www.readbyqxmd.com/read/29902472/home-based-exercise-enhances-health-related-quality-of-life-in-persons-with-spinal-cord-injury-a-randomized-controlled-trial
#16
Tom E Nightingale, Peter C Rouse, Jean-Philippe Walhin, Dylan Thompson, James L J Bilzon
OBJECTIVE: To assess the influence of a home-based exercise intervention on indices of health-related quality of life (HRQOL) in persons with spinal cord injury (SCI). DESIGN: This was a randomized controlled trial (HOMEX-SCI; ISRCTN57096451). After baseline laboratory testing and a week of free-living physical activity monitoring, eligible participants were randomly assigned (2:1 allocation ratio) to a home-based moderate-intensity upper-body exercise intervention (INT, n = 13), or a lifestyle maintenance control group (CON, n = 8), for 6 weeks...
June 11, 2018: Archives of Physical Medicine and Rehabilitation
https://www.readbyqxmd.com/read/29902224/premorbid-risk-perception-lifestyle-adherence-and-coping-strategies-of-people-with-diabetes-mellitus-a-phenomenological-study-in-the-brong-ahafo-region-of-ghana
#17
Philip Teg-Nefaah Tabong, Vitalis Bawontuo, Doris Ningwiebe Dumah, Joseph Maaminu Kyilleh, Tolgou Yempabe
BACKGROUND: One of the non-communicable diseases which is on the rise is type 2 diabetes (T2D). T2D is largely preventable with healthy lifestyle. We therefore conducted this study to explore premorbid perception of risk, behavioural practices and the coping strategies of patients with T2D. METHODS: Using descriptive phenomenology approach to qualitative enquiry, we conducted eight focus group discussions (N = 73) with diabetic patients; four among males (N = 36) and four among females (N = 37)...
2018: PloS One
https://www.readbyqxmd.com/read/29901240/a-sociological-approach-to-resilience-in-health-and-illness
#18
Christine Walker, Chris L Peterson
Work on resilience in health and illness has been approached from a number of perspectives. These are the biological and psychosocial with a focus on the individual's responses to cope and adapt to changing circumstances wrought by changing physical health states. This we argue has a place but is far too narrow emphasizing the neoliberal view that the sick or imperfect individual is ultimately responsible for their own health outcomes. In this perspective, the individual's failure to cope or adapt may be seen as a personal failure to interact with the health system on offer...
June 14, 2018: Journal of Evaluation in Clinical Practice
https://www.readbyqxmd.com/read/29899429/dietary-intake-of-curcumin-improves-eif2-signaling-and-reduces-lipid-levels-in-the-white-adipose-tissue-of-obese-mice
#19
Masuko Kobori, Yumiko Takahashi, Hiroaki Takeda, Masatomo Takahashi, Yoshihiro Izumi, Yukari Akimoto, Mutsumi Sakurai, Hideaki Oike, Toshiyuki Nakagawa, Masanori Itoh, Takeshi Bamba, Toshiyuki Kimura
White adipose tissue (eWAT) plays a crucial role in preventing metabolic syndrome. We aimed to investigate WAT distribution and gene expression and lipidomic profiles in epididymal WAT (eWAT) in diet-induced obese mice, reflecting a Western-style diet of humans to elucidate the bioactive properties of the dietary antioxidant curcumin in preventing lifestyle-related diseases. For 16 weeks, we fed C57BL/6J mice with a control diet, a high-fat, high-sucrose and high-cholesterol Western diet or Western diet supplemented with 0...
June 13, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29899044/human-genetics-of-obesity-and-type-2-diabetes-mellitus-past-present-and-future
#20
REVIEW
Erik Ingelsson, Mark I McCarthy
Type 2 diabetes mellitus (T2D) and obesity already represent 2 of the most prominent risk factors for cardiovascular disease, and are destined to increase in importance given the global changes in lifestyle. Ten years have passed since the first round of genome-wide association studies for T2D and obesity. During this decade, we have witnessed remarkable developments in human genetics. We have graduated from the despair of candidate gene-based studies that generated few consistently replicated genotype-phenotype associations, to the excitement of an exponential harvest of loci robustly associated with medical outcomes through ever larger genome-wide association study meta-analyses...
June 2018: Circulation. Genomic and precision medicine
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