Fang Yan, Qian Da, Hongmei Yi, Shijie Deng, Lifeng Zhu, Mu Zhou, Yingting Liu, Ming Feng, Jing Wang, Xuan Wang, Yuxiu Zhang, Wenjing Zhang, Xiaofan Zhang, Jingsheng Lin, Shaoting Zhang, Chaofu Wang
Diffuse large B cell lymphoma (DLBCL) is an aggressive blood cancer known for its rapid progression and high incidence. The growing use of immunohistochemistry (IHC) has significantly contributed to the detailed cell characterization, thereby playing a crucial role in guiding treatment strategies for DLBCL. In this study, we developed an AI-based image analysis approach for assessing PD-L1 expression in DLBCL patients. PD-L1 expression represents as a major biomarker for screening patients who can benefit from targeted immunotherapy interventions...
March 27, 2024: NPJ Precision Oncology