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Electrical stimulators

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https://www.readbyqxmd.com/read/29778809/effects-of-propofol-on-ipscs-in-ca1-and-dentate-gyrus-cells-of-rat-hippocampus-propofol-effects-on-hippocampal-cells-ipscs
#1
Masanori Ishiguro, Suguru Kobayashi, Kiyoji Matsuyama, Takashi Nagamine
Propofol (2, 6-diisopropylphenol) is one of the most popular intravenous anesthetic agents. In this study, we compared the effects of propofol on inhibitory postsynaptic currents (IPSCs) induced by single and paired electrical stimulations in CA1 pyramidal cells (CA1-PCs) and dentate gyrus granule cells (DG-GCs) in rat hippocampal slices using the whole cell patch-clamp technique. In the absence of propofol, the amplitude of evoked IPSC by single stimulation and decay time constants were stable in both CA1-PCs and DG-GCs for 30 min...
May 17, 2018: Neuroscience Research
https://www.readbyqxmd.com/read/29777714/efficiency-of-neuromuscular-electrical-stimulation-and-transcutaneous-nerve-stimulation-on-hemiplegic-shoulder-pain-a-prospective-randomized-controlled-trial
#2
Meimei Zhou, Fang Li, Weibo Lu, Junfa Wu, Song Pei
OBJECTIVE: To compare the efficacy of neuromuscular electrical stimulation (NMES) and transcutaneous nerve stimulation (TENS) on hemiplegic shoulder pain (HSP). DESIGN: This is a prospective randomized controlled trial (RCT). SETTING: A total of 184 HSP patients, aged 18-80 years, were recruited in the Rehabilitation Hospital from February 2014 to July 2016. The Ethics approval was obtained from the Institutional Review Board of the Hospital...
May 16, 2018: Archives of Physical Medicine and Rehabilitation
https://www.readbyqxmd.com/read/29777332/influence-of-tetanic-stimulation-on-the-staircase-phenomenon-and-the-acceleromyographic-time-course-of-neuromuscular-block-a-randomized-controlled-trial
#3
Guido Mazzinari, Carlos L Errando, Oscar Díaz-Cambronero, Manuel Martin-Flores
During neuromuscular monitoring, repeated electrical stimulation evokes muscle responses of increasing magnitude ('staircase phenomenon', SP). We aimed to evaluate whether SP affects time course and twitches' values of an acceleromyographic assessed neuromuscular block with or without previous tetanic stimulation. Fifty adult patients were randomized to receive a 50 Hz tetanic stimulus (S group) or not (C group) before monitor calibration. After 20 min of TOF ratio (TOFr) stimulation rocuronium was administered...
May 18, 2018: Journal of Clinical Monitoring and Computing
https://www.readbyqxmd.com/read/29777277/impact-of-muscle-atrophy-on-bone-metabolism-and-bone-strength-implications-for-muscle-bone-crosstalk-with-aging-and-disuse
#4
REVIEW
T Bettis, B-J Kim, M W Hamrick
Bone fractures in older adults are often preceded by a loss of muscle mass and strength. Likewise, bone loss with prolonged bed rest, spinal cord injury, or with exposure to microgravity is also preceded by a rapid loss of muscle mass. Recent studies using animal models in the setting of hindlimb unloading or botulinum toxin (Botox) injection also reveal that muscle loss can induce bone loss. Moreover, muscle-derived factors such as irisin and leptin can inhibit bone loss with unloading, and knockout of catabolic factors in muscle such as the ubiquitin ligase Murf1 or the myokine myostatin can reduce osteoclastogenesis...
May 18, 2018: Osteoporosis International
https://www.readbyqxmd.com/read/29777193/on-spiking-behaviour-of-oyster-fungi-pleurotus-djamor
#5
Andrew Adamatzky
We recorded extra-cellular electrical potential of fruit bodies of oyster fungi Pleurotus djamor. We demonstrated that the fungi generate action potential like impulses of electrical potential. Trains of the spikes are observed. Two types of spiking activity are uncovered: high-frequency (period 2.6 min) and low-frequency (period 14 min); transitions between modes of spiking are illustrated. An electrical response of fruit bodies to short (5 sec) and long (60 sec) thermal stimulation with open flame is analysed in details...
May 18, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29776999/stumbling-corrective-reaction-elicited-by-mechanical-and-electrical-stimulation-of-the-saphenous-nerve-in-walking-mice
#6
William Paganini Mayer, Turgay Akay
The ability to walk around in a natural environment requires the capacity to cope with unexpected obstacles that may disrupt locomotion. One such mechanism is called the stumbling corrective reaction (SCR) that enables animals to step over obstacles that would otherwise disturb the progression of swing movement. Here we use in vivo motion analysis and physiological recording techniques to describe the SCR in mice. We show that SCR can be elicited consistently in mice during locomotion by inserting an obstacle along the path of leg movement during swing phase...
May 18, 2018: Journal of Experimental Biology
https://www.readbyqxmd.com/read/29776678/asystole-a-few-seconds-after-the-electrical-stimulation-of-electroconvulsive-therapy
#7
Shunsuke Takagi, Yuuya Terasawa, Takashi Takeuchi
No abstract text is available yet for this article.
March 23, 2018: Psychosomatics
https://www.readbyqxmd.com/read/29775490/monolithic-flexible-vertical-gan-light-emitting-diodes-for-a-transparent-wireless-brain-optical-stimulator
#8
Han Eol Lee, JeHyuk Choi, Seung Hyun Lee, Minju Jeong, Jung Ho Shin, Daniel J Joe, DoHyun Kim, Chang Wan Kim, Jung Hwan Park, Jae Hee Lee, Daesoo Kim, Chan-Soo Shin, Keon Jae Lee
Flexible inorganic-based micro light-emitting diodes (µLEDs) are emerging as a significant technology for flexible displays, which is an important area for bilateral visual communication in the upcoming Internet of Things era. Conventional flexible lateral µLEDs have been investigated by several researchers, but still have significant issues of power consumption, thermal stability, lifetime, and light-extraction efficiency on plastics. Here, high-performance flexible vertical GaN light-emitting diodes (LEDs) are demonstrated by silver nanowire networks and monolithic fabrication...
May 18, 2018: Advanced Materials
https://www.readbyqxmd.com/read/29774960/alteration-of-nociceptive-integration-in-the-spinal-cord-of-a-rat-model-of-parkinson-s-disease
#9
Keri-Ann Charles, Frédéric Naudet, Rabia Bouali-Benazzouz, Marc Landry, Philippe De Deurwaerdère, Pascal Fossat, Abdelhamid Benazzouz
BACKGROUND: Pain is a major non motor symptom that contributes to impaired quality of life in PD. However, its mechanism is unknown. OBJECTIVES AND METHODS: We sought to identify the pain phenotypes and parallel changes in spinal integration of peripheral stimuli in a rat model of PD induced by lesions of SN dopamine neurons, using behavioral plantar and von Frey tests as well as electrophysiology of the dorsal horn. RESULTS: We show that dopamine depletion by 6-OHDA induced hypersensitivity to mechanical and thermal stimuli...
May 18, 2018: Movement Disorders: Official Journal of the Movement Disorder Society
https://www.readbyqxmd.com/read/29773801/lrrc8-vrac-anion-channels-enhance-%C3%AE-cell-glucose-sensing-and-insulin-secretion
#10
Till Stuhlmann, Rosa Planells-Cases, Thomas J Jentsch
Glucose homeostasis depends critically on insulin that is secreted by pancreatic β-cells. Serum glucose, which is directly sensed by β-cells, stimulates depolarization- and Ca2+ -dependent exocytosis of insulin granules. Here we show that pancreatic islets prominently express LRRC8A and LRRC8D, subunits of volume-regulated VRAC anion channels. Hypotonicity- or glucose-induced β-cell swelling elicits canonical LRRC8A-dependent VRAC currents that depolarize β-cells to an extent that causes electrical excitation...
May 17, 2018: Nature Communications
https://www.readbyqxmd.com/read/29772954/electric-acoustic-stimulation-suppresses-tinnitus-in-a-subject-with-high-frequency-single-sided-deafness
#11
Griet Mertens, Vincent Van Rompaey, Paul Van de Heyning
BACKGROUND: A suggested solution to suppress tinnitus is to restore the normal sensory input. This is based on the auditory deprivation hypothesis. It is known that hearing aids can provide sufficient activation of the auditory nervous system and reduce tinnitus in subjects with mild to moderate hearing loss and that cochlear implantation can reduce tinnitus in subjects with severe to profound hearing loss. This applies to subjects with single-sided deafness (SSD) or bilateral hearing loss...
May 17, 2018: Cochlear Implants International
https://www.readbyqxmd.com/read/29772343/brain-stimulation-differentially-modulates-nociception-and-inflammation-in-aversive-and-non-aversive-behavioural-conditions
#12
G S Bassi, A Kanashiro, G J Rodrigues, F Q Cunha, N C Coimbra, L Ulloa
Inflammation and pain are major clinical burdens contributing to multiple disorders and limiting the quality of life of patients. We previously reported that brain electrical stimulation can attenuate joint inflammation in experimental arthritis. Here, we report that non-aversive electrical stimulation of the locus coeruleus (LC), the paraventricular hypothalamic nucleus (PVN) or the ventrolateral column of the periaqueductal grey matter (vlPAG) decreases thermal pain sensitivity, knee inflammation and synovial neutrophilic infiltration in ratswith intra-articular zymosan...
May 14, 2018: Neuroscience
https://www.readbyqxmd.com/read/29772187/platelet-rich-plasma-releasate-promotes-regeneration-and-decreases-inflammation-and-apoptosis-of-injured-skeletal-muscle
#13
Wen-Chung Tsai, Tung-Yang Yu, Gwo-Jyh Chang, Li-Ping Lin, Miao-Sui Lin, Jong-Hwei S Pang
BACKGROUND: Platelet-rich plasma (PRP) contains various cytokines and growth factors that may be beneficial to the healing process of injured muscle. Based on the authors' previous study, PRP releasate can promote proliferation and migration of skeletal muscle cells in vitro, so animal studies are performed to support the use of PRP to treat muscle injury in vivo. PURPOSE: To investigate the effect of PRP releasate on regeneration of injured muscle, as well as its effect on inflammatory reaction and cell apoptosis, in the early stages of the muscle-healing process...
May 1, 2018: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/29770647/neuromodulation-for-tinnitus-treatment-an-overview-of-invasive-and-non-invasive-techniques
#14
REVIEW
Nicole Peter, Tobias Kleinjung
Tinnitus is defined as a perception of sound without any external sound source. Chronic tinnitus is a frequent condition that can affect the quality of life. So far, no causal cure for tinnitus has been documented, and most pharmacologic and psychosomatic treatment modalities aim to diminish tinnitus' impact on the quality of life. Neuromodulation, a novel therapeutic modality, which aims at alternating nerve activity through a targeted delivery of a stimulus, has emerged as a potential option in tinnitus treatment...
March 12, 2018: Journal of Zhejiang University. Science. B
https://www.readbyqxmd.com/read/29770490/functional-magnetic-resonance-electrical-impedance-tomography-fmreit-sensitivity-analysis-using-an-active-bidomain-finite-element-model-of-neural-tissue
#15
Rosalind J Sadleir, Fanrui Fu, Munish Chauhan
PURPOSE: A direct method of imaging neural activity was simulated to determine typical signal sizes. METHODS: An active bidomain finite-element model was used to estimate approximate perturbations in MR phase data as a result of neural tissue activity, and when an external MR electrical impedance tomography imaging current was added to the region containing neural current sources. RESULTS: Modeling-predicted, activity-related conductivity changes should produce measurable differential phase signals in practical MR electrical impedance tomography experiments conducted at moderate resolution at noise levels typical of high field systems...
May 16, 2018: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/29768013/synergistic-effects-of-electrical-stimulation-and-aligned-nanofibrous-microenvironment-on-growth-behaviour-of-mesenchymal-stem-cells
#16
Lin Jin, Bin Hu, Zhanrong Li, Jingguo Li, Yanzheng Gao, Zhenling Wang, Jianhua Hao
Incontrollable cellular growth behaviour is a significant issue that severely affects the functional tissue formation and cellular protein expression. Development of natural extracellular matrix (ECM) like biomaterials to present microenvironment cues for the regulation of cell responses can effectively overcome this problem. The external simulation and topological characteristics as guiding cues are capable of providing diverse influences on cellular growth. Herein, we developed two dimensional aligned conductive nanofibers (2D-ACNFs) by electrospinning process and surface polymerization, and provided the effects of both alignment and electrical stimulation (ES) on cellular response of human mesenchymal cells (hMSCs)...
May 16, 2018: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/29767958/distinguishing-between-deep-trapping-transients-of-electrons-and-holes-in-tio2-nanotube-arrays-using-planar-microwave-resonator-sensor
#17
Mohammad H Zarifi, Benjamin Daniel Wiltshire, Najia Mahdi, Karthik Shankar, Mojgan Daneshmand
A large signal DC bias and a small signal microwave bias were simultaneously applied to TiO2 nanotube membranes mounted on a planar microwave resonator. The DC bias modulated the electron concentration in the TiO2 nanotubes, and was varied between 0 and 120 V in this study. Transients immediately following the application and removal of DC bias were measured by monitoring the S-parameters of the resonator as a function of time. The DC bias stimulated Poole-Frenkel type trap-mediated electrical injection of excess carriers into TiO2 nanotubes which resulted in a near constant resonant frequency but a pronounced decrease in the microwave amplitude due to free electron absorption...
May 16, 2018: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/29766591/bilateral-activations-in-operculo-insular-area-show-temporal-dissociation-after-peripheral-electrical-stimulation-in-healthy-adults
#18
Pekka Hautasaari, Harri Saloranta, Andrej M Savić, Katariina Korniloff, Urho M Kujala, Ina M Tarkka
Interhemispheric transfer is necessary for sensory integration and coordination of body sides. We studied how somatosensory input from one body side may reach both body sides. First, we investigated with 17 healthy adults which uni- and bilateral brain areas were involved in consecutive stages of automatic sensory processing of non-nociceptive peripheral stimulation. Somatosensory evoked fields (SEFs) to electrical stimulation were recorded with 306-channel magnetoencephalography in two conditions. First, SEFs were registered following sensory radial nerve (RN) stimulation to dorsal surface of the right hand and second, following median nerve (MN) stimulation at the right wrist...
May 15, 2018: European Journal of Neuroscience
https://www.readbyqxmd.com/read/29766458/cerebellar-stimulation-evoked-prefrontal-electrical-synchrony-is-modulated-by-gaba
#19
Xiaoming Du, Laura M Rowland, Ann Summerfelt, Fow-Sen Choa, George F Wittenberg, Krista Wisner, Andrea Wijtenburg, Joshua Chiappelli, Peter Kochunov, L Elliot Hong
Cerebellar-prefrontal connectivity has been recognized as important for behaviors ranging from motor coordination to cognition. Many of these behaviors are known to involve excitatory or inhibitory modulations from the prefrontal cortex. We used cerebellar transcranial magnetic stimulation (TMS) with simultaneous electroencephalography (EEG) to probe cerebellar-evoked electrical activity in prefrontal cortical areas and used magnetic resonance spectroscopy (MRS) measures of prefrontal GABA and glutamate levels to determine if they are correlated with those potentials...
May 15, 2018: Cerebellum
https://www.readbyqxmd.com/read/29766393/linear-feature-projection-based-real-time-decoding-of-limb-state-from-dorsal-root-ganglion-recordings
#20
Sungmin Han, Jun-Uk Chu, Jong Woong Park, Inchan Youn
Proprioceptive afferent activities recorded by a multichannel microelectrode have been used to decode limb movements to provide sensory feedback signals for closed-loop control in a functional electrical stimulation (FES) system. However, analyzing the high dimensionality of neural activity is one of the major challenges in real-time applications. This paper proposes a linear feature projection method for the real-time decoding of ankle and knee joint angles. Single-unit activity was extracted as a feature vector from proprioceptive afferent signals that were recorded from the L7 dorsal root ganglion during passive movements of ankle and knee joints...
May 15, 2018: Journal of Computational Neuroscience
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