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Shinya Kimata, Daichi Mochizuki, Junichi Satoh, Ken Kitano, Yu Kanesaki, Kouji Takeda, Akira Abe, Shinji Kawasaki, Youichi Niimura
Amphibacillus xylanus is a recently identified bacterium which grows well under both aerobic and anaerobic conditions and may prove useful for biomass utilization. Amphibacillus xylanus, despite lacking a respiratory chain, consumes oxygen at a similar rate to Escherichia coli (130-140 μmol oxygen·min-1 ·g-1 dry cells at 37 °C), suggesting that it has an alternative system that uses a large amount of oxygen. Amphibacillus xylanus NADH oxidase (Nox) was previously reported to rapidly reduce molecular oxygen content in the presence of exogenously added free flavin...
June 2018: FEBS Open Bio
Takaaki Kanazawa, Kazunari Tomita, Keikichi Kawasaki, Toshio Yagi, Yuji Tanabe, Katsunori Inagaki
Background  The Frag-Loc (FL) compression screw system was designed to stabilize dorsally displaced intra-articular dorsoulnar (die-punch) fragments in distal radius fractures. Purpose  Comparison of the biomechanical properties of fixation of the die-punch fragment (stiffness, ultimate strength, and displacement ratio of the fragment), using the FL and traditional locking screw (LS), and using simulated distal radial fractures in cadaveric specimens under axial compressive loading. Both screws were used with a volar locking plate (VLP)...
July 2018: Journal of Wrist Surgery
Najib Advani, Sudigdo Sastroasmoro, Teddy Ontoseno, Cuno Spm Uiterwaal
Background: Kawasaki disease (KD) is an acute systemic vasculitis syndrome with a high incidence of coronary aneurysms in untreated children. The majority of aneurysms resulting from KD are known to regress with time. Aims: This study aimed to determine the course and outcome of coronary artery dilatation in patients with KD and ascertain whether there are any differences in the outcomes in the different branches. Setting and Design: This is a retrospective cohort study of patients diagnosed with KD with midterm follow-up data...
May 2018: Annals of Pediatric Cardiology
Akifumi Komura, Tomohiro Kawasaki, Yuichi Yamada, Shiho Uzuyama, Yoshitaka Asano, Jun Shinoda
The aim of this study is to investigate glucose uptake on FDG-PET in patients with chronic mental and cognitive symptoms following a single blunt mild traumatic brain injury (TBI) and without visible brain lesions on CT/MRI. Eighty-nine consecutive patients (mean age 43.8±10.75) who had a single blunt mild TBI from a traffic accident and suffering from chronic mental and cognitive symptoms without visible brain lesions on CT/MRI were enrolled in the study. Patients underwent FDG-PET imaging, and the mean interval between the TBI and FDG-PET was 50...
June 19, 2018: Journal of Neurotrauma
Shigeomi Yokoya, Aiko Tamura, Akihiko Hino, Masamichi Bamba, Toshikazu Kato, Hidesato Takezawa, Yukihiro Goto, Hideki Oka, Akihiro Fujii
BACKGROUND: Kawasaki disease (KD) is an acute systemic vasculitis that primarily affects the coronary artery, but does not commonly affect the carotid artery. Cerebral infarction (CI) with internal carotid artery stenosis (ICS) in patients with KD had never been reported. We report a patient with CI as a remote phase complication of KD. CASE PRESENTATION: A 32-year-old man presented with impaired consciousness. Magnetic resonance imaging scan (MRI) and digital subtraction angiogram (DSA) confirmed CI and ICS...
June 16, 2018: World Neurosurgery
Juntaro Koyama, Yasuhiro Kaiho, Yoshihide Kawasaki, Tomonori Sato, Taro Fukushi, Atsushi Kyan, Yoichi Arai
OBJECTIVES: The phosphodiesterase type 5 inhibitor tadalafil is one of the first-choice drugs for benign prostate hyperplasia (BPH) patients with lower urinary tract symptoms (LUTS). However, tadalafil is not always equally beneficial to every patient. In order to determine whether penile blood pressure (PBP) can be used to identify patients who can benefit from tadalafil treatment, the correlation between PBP at baseline and changes in LUTS induced by tadalafil treatment was studied prospectively...
June 19, 2018: BJU International
Minami Kawasaki, Jerome Delamare-Deboutteville, Rachel O Bowater, Mark J Walker, Scott Beatson, Nouri L Ben Zakour, Andrew C Barnes
Streptococcus agalactiae (GBS) causes disease in a wide range of animals. The serotype Ib lineage is highly adapted to aquatic hosts, exhibiting substantial genome reduction compared with terrestrial conspecifics. Here we sequence genomes from 40 GBS isolates including 25 from wild fish and captive stingrays in Australia, six local veterinary or human clinical isolates, and nine isolates from farmed tilapia in Honduras and compare with 42 genomes from public databases. Phylogenetic analysis based on non-recombinant core genome SNPs indicated that aquatic serotype Ib isolates from Queensland were distantly related to local veterinary and human clinical isolates...
June 18, 2018: Applied and Environmental Microbiology
Xu Guo, Xiaoou Wang, Xinzhong Zhang, Ahmed O Ahmed, David H Hsi, Daqing Zhang
BACKGROUND: Kawasaki disease is an acute febrile disease with mucocutaneous and cardiovascular involvement affecting infants and young children. Though coronary artery abnormalities are common in Kawasaki disease, no consensus has been reached regarding the treatment of acute coronary artery diseases in this population. CASE PRESENTATION: We described a case of myocardial infarction triggered by blunt chest wall trauma in a 20 years old girl. She presented with chest pain and breathlessness with brief syncope, lab results and electrocardiogram findings were consistent with acute myocardial infarction...
June 18, 2018: BMC Cardiovascular Disorders
Jung Sook Yeom, Young Hye Cho, Chung Mo Koo, Jin Su Jun, Ji Sook Park, Eun Sil Park, Ji-Hyun Seo, Jae-Young Lim, Hyang-Ok Woo, Hee-Shang Youn
Cerebral vasculitis is thought to be a possible underlying mechanism of severe neurological complications of Kawasaki's disease (KD), such as cerebral infarct or aneurysm rupture. To evaluate the intracranial inflammatory response in patients with acute-stage KD, we measured the levels of cytokines (interleukin [IL]-6 and tumor necrosis factor [TNF]-α) and pentraxin-3 (PTX3) in the cerebrospinal fluid of patients with KD ( n  = 7) and compared the levels to those of the age- and sex-matched febrile control patients (bacterial meningitis [ n  = 5], enteroviral meningitis [ n  = 10], nonspecific viral illness without central nervous system involvement [ n  = 10])...
June 18, 2018: Neuropediatrics
Gauthier Blonz, Sylvie Lacroix, Nadir Benbrik, Karine Warin-Fresse, Agathe Masseau, David Trewick, Mohamed Hamidou, Jean-Louis Stephan, Antoine Néel
No abstract text is available yet for this article.
June 15, 2018: Journal of Clinical Rheumatology: Practical Reports on Rheumatic & Musculoskeletal Diseases
Liliana Tavares, Conceição Calhau, Jorge Polónia
INTRODUCTION: The migration of African populations to Europe poses problems of adaptation that may increase the risk of cardiovascular disease. We assessed the cardiovascular risk of Cape Verdean university students studying in Portugal (CV-PT) compared to Cape Verdean university students in Cape Verde (CV-CV) and to Caucasian university students in Portugal (PT-PT). METHODS: A cross-sectional study was performed comparing three university populations, 54-62% female, aged 19-28 years: CV-PT (n=104), CV-CV (n=100) and PT-PT (n=100)...
June 14, 2018: Portuguese Journal of Cardiology: An Official Journal of the Portuguese Society of Cardiology
Li Zhang, Jinxin Wang, Di Che, Yanfei Wang, Xing Rong, Lei Pi, Yufen Xu, Wei Li, Ping Huang, Maoping Chu, Xiaoqiong Gu
miRNA-146a plays a critical role in innate immune and inflammatory responses. Kawasaki disease involves immune-mediated inflammatory responses, which lead to vascular endothelial injury. However, there has been no study on the association between the miRNA-146a rs2910164 C>G polymorphism and Kawasaki disease risk. We enrolled 532 Kawasaki disease patients and 623 healthy controls from a southern Chinese population, and the miRNA-146a rs2910164 C>G polymorphism was genotyped by the TaqMan method. There was no evidence that this polymorphism was associated with Kawasaki disease...
June 14, 2018: Bioscience Reports
Jae Yun Jung, Eun Mi Ham, Hyuksool Kwon, Young Ho Kwak, Do Kyun Kim, Jin Hee Lee, Jin Hee Jung
BACKGROUND: Coronary artery dilatation (CAD) is a great concern with Kawasaki disease (KD). This study aimed to investigate the relationship between serum N-terminal pro-brain natriuretic peptide (NT-proBNP) levels and CAD in patients with the hyperacute phase (≤4 days of fever) of KD. METHODS: Serum NT-proBNP levels were compared between patients with and those without CAD, who underwent transthoracic echocardiography (TTE) within 24 h of the hyperacute phase of KD in the pediatric emergency department (PED)...
June 8, 2018: American Journal of Emergency Medicine
Toshiki Kuno, Akimichi Shibata, Masaki Kodaira, Yohei Numasawa
No abstract text is available yet for this article.
June 12, 2018: Circulation Journal: Official Journal of the Japanese Circulation Society
Kimya Hassani-Ardakani, Thusanth Thuraisingam, Duc-Vinh Thai, Rayan Alkhodair, Van-Hung Nguyen, Sarah Campillo, Barbara Miedzybrodzki, Fatemeh Jafarian
No abstract text is available yet for this article.
July 2018: JAAD Case Reports
Yun-Shan Li, Yuko Ootsuyama, Yuya Kawasaki, Yasuo Morimoto, Toshiaki Higashi, Kazuaki Kawai
Nanoparticles are widely used as useful industrial materials. Therefore, their possible adverse health effects must be appraised. We assessed and compared the oxidative DNA damage caused by four different nanoparticles (TiO2 , NiO, ZnO and CeO2 ). The effects of the administration methods, intratracheal instillation and inhalation, were also evaluated. Rats were subjected to intratracheal instillations or 4 weeks of inhalation exposure to the nanoparticles, and the 8-hydroxydeoxyguanosine (8-OHdG) levels in the lung were analyzed by an HPLC-EC detector method...
May 2018: Journal of Clinical Biochemistry and Nutrition
Luisa Berenise Gamez-Gonzalez, Isabel Moribe-Quintero, Martin Cisneros-Castolo, Javier Varela-Ortiz, Mireya Muñoz-Ramírez, Martin Garrido-García, Marco Yamazaki-Nakashimada
BACKGROUND: Kawasaki disease shock syndrome (KDSS) is an uncommon presentation of Kawasaki disease (KD). KDSS has been associated with more severe markers of inflammation, coronary abnormalities and IVIG resistance. METHODS: A retrospective, descriptive study of children with KDSS in two hospitals was performed. Relevant articles about KD and shock were collected, demographic data, clinical presentation, laboratory variables, echocardiogram findings, treatment and special features were analyzed when available...
June 11, 2018: Pediatrics International: Official Journal of the Japan Pediatric Society
Michihiro Satoh, Takahisa Murakami, Kei Asayama, Takuo Hirose, Masahiro Kikuya, Ryusuke Inoue, Megumi Tsubota-Utsugi, Keiko Murakami, Ayako Matsuda, Azusa Hara, Taku Obara, Ryo Kawasaki, Kyoko Nomura, Hirohito Metoki, Koichi Node, Yutaka Imai, Takayoshi Ohkubo
BACKGROUND: N-terminal pro-B-type natriuretic peptide (NT-proBNP) has been used for risk stratification in heart failure or acute coronary syndrome, but the beyond 5-year predictive value of NT-proBNP for stroke remains an unsettled issue in Asian patients. The aim of the present study was to clarify this point.Methods and Results:We followed 1,198 participants (33.4% men; mean age, 60.5±11.1 years old) in the Japanese general population for a median of 13.0 years. A first stroke occurred in 93 participants...
June 9, 2018: Circulation Journal: Official Journal of the Japanese Circulation Society
R Y Gou, F Wang, X Y Dong
No abstract text is available yet for this article.
June 2, 2018: Zhonghua Er Ke za Zhi. Chinese Journal of Pediatrics
Joseph R Calabrese, Na Jin, Brian Johnson, Pedro Such, Ross A Baker, Jessica Madera, Peter Hertel, Jocelyn Ottinger, Joan Amatniek, Hiroaki Kawasaki
BACKGROUND: The long-acting injectable antipsychotic aripiprazole once-monthly 400 mg (AOM 400) was recently approved for maintenance treatment of bipolar I disorder (BP-I). The purpose of this study was to evaluate the safety, tolerability, and efficacy of AOM 400 as long-term maintenance treatment for BP-I. METHODS: This open-label multicenter study evaluated the effectiveness of AOM 400 as maintenance treatment for BP-I by assessing safety and tolerability (primary objective) and efficacy (secondary objective)...
June 10, 2018: International Journal of Bipolar Disorders
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