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https://www.readbyqxmd.com/read/28736228/dbz-is-a-putative-ppar%C3%AE-agonist-that-prevents-high-fat-diet-induced-obesity-insulin-resistance-and-gut-dysbiosis
#1
Pengfei Xu, Fan Hong, Jialin Wang, Jing Wang, Xia Zhao, Sheng Wang, Tingting Xue, Jingwei Xu, Xiaohui Zheng, Yonggong Zhai
BACKGROUND: The nuclear receptor PPARγ is an effective pharmacological target for some types of metabolic syndrome, including obesity, diabetes, nonalcoholic fatty liver disease, and cardiovascular disease. However, the current PPARγ-targeting thiazolidinedione drugs have undesirable side effects. Danshensu Bingpian Zhi (DBZ), also known as tanshinol borneol ester derived from Salvia miltiorrhiza, is a synthetic derivative of natural compounds used in traditional Chinese medicine for its anti-inflammatory activity...
July 20, 2017: Biochimica et Biophysica Acta
https://www.readbyqxmd.com/read/28734324/adolescence-and-later-life-disease-burden-quantifying-the-contribution-of-adolescent-tobacco-initiation-from-longitudinal-cohorts
#2
Russell M Viner, Dougal S Hargreaves, Janaina Vieira Dos Santos Motta, Bernardo Horta, Ali H Mokdad, George Patton
PURPOSE: Adolescence is a time of initiation of behaviors leading to noncommunicable diseases (NCDs). We use tobacco to illustrate a novel method for assessing the contribution of adolescence to later burden. METHODS: Data on initiation of regular smoking during adolescence (10-19 years) and current adult smoking were obtained from the 1958 British Birth Cohort, the U.S. National Longitudinal Study of Adolescent Health (Add Health), the Pelotas 1982 Birth Cohort, and the Victorian Adolescent Health Cohort Study...
August 2017: Journal of Adolescent Health: Official Publication of the Society for Adolescent Medicine
https://www.readbyqxmd.com/read/28726795/a-retrospective-analysis-of-hypertension-screening-at-a-mass-gathering-in-india-implications-for-non-communicable-disease-control-strategies
#3
S Balsari, P Vemulapalli, M Gofine, K Oswal, R Merchant, S Saunik, G Greenough, T Khanna
Cardiovascular disease is the leading case of mortality from non-communicable diseases (NCD) in India. The government's National Programme for Prevention and Control of Cancer, Diabetes, Cardiovascular Diseases and Stroke seeks to increase capacity building, screening, referral and management of NCDs across India, and includes community-based outreach and screening programmes. The government in India routinely provides basic care at religious mass gatherings. However, in 2015, at the Kumbh Mela in Nashik and Trimbakeshwar, the state government extended its services to include a hypertension screening programme...
July 20, 2017: Journal of Human Hypertension
https://www.readbyqxmd.com/read/28725259/cardiovascular-disease-risk-and-prevention-amongst-syrian-refugees-mixed-methods-study-of-m%C3%A3-decins-sans-fronti%C3%A3-res-programme-in-jordan
#4
Dylan R J Collins, Kiran Jobanputra, Thomas Frost, Shoaib Muhammed, Alison Ward, Abed Alrazzaq Shafei, Taissir Fardous, Sadeq Gabashneh, Carl Heneghan
BACKGROUND: The growing burden of non-communicable diseases (NCDs) presented new challenges for medical humanitarian aid and little was known about primary health care approaches for these diseases in humanitarian response. We aimed to evaluate Médecins Sans Frontières (MSF's) use of total CVD risk based prevention strategies amongst Syrian refugees in northern Jordan to identify opportunities to improve total CVD risk based guidance for humanitarian settings. METHODS: We evaluated CVD risk assessment and management in two outpatient NCD clinics in the Irbid governorate of Jordan using a mixed methods design with qualitative and quantitative strands of equal priority, integrated during data collection and interpretation...
2017: Conflict and Health
https://www.readbyqxmd.com/read/28719772/inequalities-in-household-catastrophic-health-expenditure-and-impoverishment-associated-with-noncommunicable-diseases-in-chi-linh-hai-duong-vietnam
#5
Vu Duy Kien, Hoang Van Minh, Nguyen Bao Ngoc, Tran Bich Phuong, Tran Thu Ngan, Mikkel B Quam
A costly modern-day double burden, the expenses of noncommunicable diseases (NCDs) are becoming a devastating epidemic. The World Health Organization estimates $7 trillion in economic losses from NCDs in 2011-2025. Although regarded as affluent diseases, the burden of NCDs is shifting into poorer groups. In this study, we assessed the socioeconomic inequalities in catastrophic health expenditure and impoverishment associated with NCDs in Northern Vietnam. We also identified associated factors for catastrophic health expenditure and impoverishment...
July 2017: Asia-Pacific Journal of Public Health
https://www.readbyqxmd.com/read/28718712/comparison-of-domains-of-self-reported-physical-activity-between-kenyan-adult-urban-slum-dwellers-and-national-estimates
#6
Hilde E Groot, Stella K Muthuri
BACKGROUND: Non-communicable diseases (NCDs) - largely the result of modifiable behavioral risks such as physical inactivity that gradually develop into physiological risks - are a main cause of morbidity and mortality worldwide. In Kenya, a nationally representative STEPwise survey of risk factors for NCDs established that 10.8% of Kenyans accumulated low levels of total physical activity. OBJECTIVES: The goal of our analyses was to compare domains of self-reported physical activity in two Nairobi slums to national estimates...
2017: Global Health Action
https://www.readbyqxmd.com/read/28708740/experiences-of-substitute-decision-makers-in-making-decisions-for-older-persons-diagnosed-with-major-neurocognitive-disorder-at-end-of-life-a-qualitative-systematic-review-protocol
#7
Sarah J Cresp, Susan F Lee, Cheryle Moss
The objective of this systematic review is to identify and synthesize the best available qualitative evidence on how substitute decision makers (SDMs) are affected by and experience making decisions at end of life (EOL) for older persons diagnosed with major neurocognitive disorder (major NCD) (dementia). Addressing the objective will provide an understanding of SDMs' experiences of making decisions for older persons diagnosed with major NCD at EOL, in order to tailor supportive education and interventions and potentially decrease inopportune outcomes...
July 2017: JBI Database of Systematic Reviews and Implementation Reports
https://www.readbyqxmd.com/read/28705242/non-communicable-diseases-and-related-risk-behaviors-among-men-and-women-living-with-hiv-in-cambodia-findings-from-a-cross-sectional-study
#8
Pheak Chhoun, Chanrith Ngin, Sovannary Tuot, Khuondyla Pal, Martin Steel, Jennifer Dionisio, Hattie Pearson, Gitau Mburu, Carinne Brody, Siyan Yi
BACKGROUND: There is a growing concern for an increasing burden of non-communicable diseases (NCDs) in people living with HIV. This concern is evident especially in developing countries where dietary and lifestyle risk factors associated with NCDs are becoming more prominent. This study explored the prevalence of diabetes mellitus, hypertension, and hyperlipidemia and related risk factors in men and women living with HIV in Cambodia. METHODS: This cross-sectional study was conducted among 510 adult people living with HIV randomly selected from one city and four provinces in Cambodia...
July 14, 2017: International Journal for Equity in Health
https://www.readbyqxmd.com/read/28704405/community-health-workers-for-non-communicable-diseases-prevention-and-control-in-developing-countries-evidence-and-implications
#9
Gursimer Jeet, J S Thakur, Shankar Prinja, Meenu Singh
BACKGROUND: National programs for non-communicable diseases (NCD) prevention and control in different low middle income countries have a strong community component. A community health worker (CHW) delivers NCD preventive services using informational as well as behavioural approaches. Community education and interpersonal communication on lifestyle modifications is imparted with focus on primordial prevention of NCDs and screening is conducted as part of early diagnosis and management...
2017: PloS One
https://www.readbyqxmd.com/read/28693510/can-china-achieve-a-one-third-reduction-in-premature-mortality-from-non-communicable-diseases-by-2030
#10
Yichong Li, Xinying Zeng, Jiangmei Liu, Yunning Liu, Shiwei Liu, Peng Yin, Jinlei Qi, Zhenping Zhao, Shicheng Yu, Yuehua Hu, Guangxue He, Alan D Lopez, George F Gao, Linhong Wang, Maigeng Zhou
BACKGROUND: The United Nation's Sustainable Development Goals for 2030 include reducing premature mortality from non-communicable diseases (NCDs) by one third. To assess the feasibility of this goal in China, we projected premature mortality in 2030 of NCDs under different risk factor reduction scenarios. METHODS: We used China results from the Global Burden of Disease Study 2013 as empirical data for projections. Deaths between 1990 and 2013 for cardiovascular disease (CVD), diabetes, chronic respiratory disease, cancer, and other NCDs were extracted, along with population numbers...
July 11, 2017: BMC Medicine
https://www.readbyqxmd.com/read/28685036/mapping-the-global-research-landscape-and-knowledge-gaps-on-multimorbidity-a-bibliometric-study
#11
Xiaolin Xu, Gita D Mishra, Mark Jones
BACKGROUND: To summarize global research trends and activities on multimorbidity; then to assess the knowledge gaps and to identify implications for knowledge exchange between high income countries (HICs) and low- and middle- income countries (LMICs). METHODS: A comprehensive search was conducted to identify research publications on multimorbidity in the Web of Science(TM), as well as diabetes, depression, hypertension, and Chronic Obstructive Pulmonary Disease (COPD)...
June 2017: Journal of Global Health
https://www.readbyqxmd.com/read/28682818/respiratory-problems-in-low-resource-settings
#12
Mhoira E F Leng, Sunitha Daniel, Daniel Munday
PURPOSE OF REVIEW: Chronic breathlessness is common in patients with advanced illness who require palliative care. Achieving good symptom control can be challenging. More people with advanced illness live in low and middle income than in high-income countries, but they are much less likely to receive palliative care. Most of the emerging evidence for the palliative management of chronic breathlessness is from high-income countries. This review explores the context of chronic breathlessness in low-income settings, how evidence for control of chronic breathlessness might relate to these settings and where further work should be focused...
July 5, 2017: Current Opinion in Supportive and Palliative Care
https://www.readbyqxmd.com/read/28662836/conceptions-of-pregnancy-health-and-motivations-for-healthful-behavior-change-among-women-in-american-samoa
#13
Erica L Kocher, Jeanette M Sternberg Lamb, Stephen T McGarvey, Mata'uitafa Faiai, Bethel T Muasau-Howard, Nicola L Hawley
BACKGROUND: American Samoan women are particularly at risk of obesity-related non-communicable disease (NCD), requiring efficacious interventions to protect their health and that of their infants. Prior studies have identified pregnancy as an ideal time for behavior change interventions related to NCD. AIM: This study aimed to understand American Samoan women's conceptions of health during pregnancy, their motivations for pregnancy behavior change, and the role of their family in both enabling and preventing these changes...
June 26, 2017: Women and Birth: Journal of the Australian College of Midwives
https://www.readbyqxmd.com/read/28633351/data-compression-can-discriminate-broilers-by-selection-line-detect-haplotypes-and-estimate-genetic-potential-for-complex-phenotypes
#14
N J Hudson, R J Hawken, R Okimoto, R L Sapp, A Reverter
Accurately establishing the relationships among individuals lays the foundation for genetic analyses such as genome-wide association studies and identification of selection signatures. Of particular interest to the poultry industry are estimates of genetic merit based on molecular data. These estimates can be commercially exploited in marker-assisted breeding programs to accelerate genetic improvement. Here, we test the utility of a new method we have recently developed to estimate animal relatedness and applied it to genetic parameter estimation in commercial broilers...
June 15, 2017: Poultry Science
https://www.readbyqxmd.com/read/28632767/how-is-indonesia-coping-with-its-epidemic-of-chronic-noncommunicable-diseases-a-systematic-review-with-meta-analysis
#15
Julia Schröders, Stig Wall, Mohammad Hakimi, Fatwa Sari Tetra Dewi, Lars Weinehall, Mark Nichter, Maria Nilsson, Hari Kusnanto, Ekowati Rahajeng, Nawi Ng
BACKGROUND: Chronic noncommunicable diseases (NCDs) have emerged as a huge global health problem in low- and middle-income countries. The magnitude of the rise of NCDs is particularly visible in Southeast Asia where limited resources have been used to address this rising epidemic, as in the case of Indonesia. Robust evidence to measure growing NCD-related burdens at national and local levels and to aid national discussion on social determinants of health and intra-country inequalities is needed...
2017: PloS One
https://www.readbyqxmd.com/read/28629430/bangladesh-policy-on-prevention-and-control-of-non-communicable-diseases-a-policy-analysis
#16
Tuhin Biswas, Sonia Pervin, Md Imtiaz Alam Tanim, Louis Niessen, Anwar Islam
BACKGROUND: This paper is aimed at critically assessing the extent to which Non-Communicable Disease NCD-related policies introduced in Bangladesh align with the World Health Organization's (WHO) 2013-2020 Action Plan for the Global Strategy for the Prevention and Control of NCDs. METHODS: The authors reviewed all relevant policy documents introduced by the Government of Bangladesh since its independence in 1971. The literature review targeted scientific and grey literature documents involving internet-based search, and expert consultation and snowballing to identify relevant policy documents...
June 19, 2017: BMC Public Health
https://www.readbyqxmd.com/read/28623056/the-prevalence-and-risk-factor-control-associated-with-noncommunicable-diseases-in-china-japan-and-korea
#17
Defu Ma, Hiromichi Sakai, Chihiro Wakabayashi, Jong-Sook Kwon, Yoonna Lee, Shuo Liu, Qiaoqin Wan, Kumiko Sasao, Kanade Ito, Ken Nishihara, Peiyu Wang
BACKGROUND: Noncommunicable disease (NCD) has become the leading cause of mortality and disease burden worldwide. METHODS: A cross-sectional survey was carried out to investigate the prevalence of NCDs and risk factor control on dietary behaviors and dietary intake in China, Japan, and Korea. RESULTS: There were significant differences among the three countries on the prevalence of hypertension (24.5% in China, 17.6% in Korea, and 15.2% in Japan), diabetes (8...
June 13, 2017: Journal of Epidemiology
https://www.readbyqxmd.com/read/28619031/healthy-people-and-healthy-profits-elaborating-a-conceptual-framework-for-governing-the-commercial-determinants-of-non-communicable-diseases-and-identifying-options-for-reducing-risk-exposure
#18
REVIEW
Kent Buse, Sonja Tanaka, Sarah Hawkes
BACKGROUND: Non-communicable diseases (NCDs) represent a significant threat to human health and well-being, and carry significant implications for economic development and health care and other costs for governments and business, families and individuals. Risks for many of the major NCDs are associated with the production, marketing and consumption of commercially produced food and drink, particularly those containing sugar, salt and transfats (in ultra-processed products), alcohol and tobacco...
June 15, 2017: Globalization and Health
https://www.readbyqxmd.com/read/28617525/characterization-of-high-exopolysaccharide-producing-lactobacillus-strains-isolated-from-mustard-pickles-for-potential-probiotic-applications
#19
Jing-Yao Huang, Cheng-Yen Kao, We-Sin Liu, Tony J Fang
The aim of this study was to characterize high exopolysaccharide (EPS)-producing lactic acid bacteria (LAB) isolated from mustard pickles in Taiwan for potential probiotic applications. Among 39 collected LAB strains, four most productive EPS-producing strains were selected for further analysis. Comparative analyses of 16S rDNA genes rpoA and pheS sequences demonstrated that these strains were members of Lactobacillus plantarum-group (LPG). NCD 2, NLD 4, SLC 13, and NLD 16 showed survival rates of 95.83% ± 0...
June 2017: International Microbiology: the Official Journal of the Spanish Society for Microbiology
https://www.readbyqxmd.com/read/28607234/healthy-lifestyle-centres-a-service-for-screening-noncommunicable-diseases-through-primary-health-care-institutions-in-sri-lanka
#20
D S Virginie Mallawaarachchi, Shiranee C Wickremasinghe, Lakshmi C Somatunga, Vithanage Tsk Siriwardena, Nalika S Gunawardena
The Ministry of Health in Sri Lanka initiated the Healthy Lifestyle Centres (HLCs) in 2011, to address the lack of a structured noncommunicable disease (NCD) screening service through the lowest level of primary health-care institutions. The main service objective of the HLCs is to reduce the risk of NCDs of 40-65 year olds by detecting risk factors early and improving access to specialized care for those with a higher risk of cardiovascular disease (CVD). The screened clients are managed at HLCs, based on the total-risk approach to assess their 10-year CVD risk, using the World Health Organization/International Society of Hypertension risk-prediction chart...
September 2016: WHO South-East Asia Journal of Public Health
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