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https://www.readbyqxmd.com/read/27555779/a-simple-dietary-assessment-tool-to-monitor-food-intake-of-hospitalized-adult-patients
#1
Dwi Budiningsari, Suzana Shahar, Zahara Abdul Manaf, Susetyowati Susetyowati
BACKGROUND/OBJECTIVES: Monitoring food intake of patients during hospitalization using simple methods and minimal training is an ongoing problem in hospitals. Therefore, there is a need to develop and validate a simple, easy to use, and quick tool that enables staff to estimate dietary intake. Thus, this study aimed to develop and validate the Pictorial Dietary Assessment Tool (PDAT). SUBJECTS AND METHODS: A total of 37 health care staff members consisting of dietitians, nurses, and serving assistants estimated 130 breakfast and lunch meals consumed by 67 patients using PDAT...
2016: Journal of Multidisciplinary Healthcare
https://www.readbyqxmd.com/read/27283563/altmetric-top-50-dental-articles-in-2014
#2
J Kolahi, S Khazaei
Introduction Altmetrics is a new and emerging scholarly tool that measures online attention surrounding journal articles. Altmetric data resources include: policy documents, news outlets, blogs, online reference managers (eg Mendeley and CiteULike), post-publication peer-review forums (eg PubPeer and Publons), social media (eg Twitter, Facebook, Weibo, Google(+), Pinterest, Reddit), Wikipedia, sites running Stack Exchange (Q&A), and reviews on F1000 and YouTube.Methods To identify the top 50 dental articles in 2014, PubMed was searched using the following query "("2014/1/1"[PDAT]:"2014/12/31"[PDAT]) and jsubsetd[text]" in December, 2015...
June 10, 2016: British Dental Journal
https://www.readbyqxmd.com/read/27216435/phospholipid-diacylglycerol-acyltransferase-contributes-to-the-conversion-of-membrane-lipids-into-triacylglycerol-in-myrmecia-incisa-during-the-nitrogen-starvation-stress
#3
Xiao-Yu Liu, Long-Ling Ouyang, Zhi-Gang Zhou
In addition to the Kennedy pathway for de novo biosynthesis, triacylglycerol (TAG), the most important stock for microalgae-based biodiesel production, can be synthesized by phospholipid: diacylglycerol acyltransferase (PDAT) that transfers an acyl group from phospholipids (PLs) to diacylglycerol (DAG). This study presents a novel gene that encodes PDAT from the green microalga Myrmecia incisa Reisigl H4301 (designated MiPDAT ). MiPDAT is localized on the plasma membrane (PM) via the agroinfiltration of tobacco leaves with a green fluorescent protein-fused construct...
May 24, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27074274/cardiovascular-effects-of-shock-and-trauma-in-experimental-models-a-review
#4
Mauricio Rocha-e-Silva
Experimental models of human pathology are useful guides to new approaches towards improving clinical and surgical treatments. A systematic search through PubMed using the syntax (shock) AND (trauma) AND (animal model) AND (cardiovascular) AND ("2010/01/01"[PDat]: "2015/12/31"[PDat]) found 88 articles, which were reduced by manual inspection to 43 entries. These were divided into themes and each theme is subsequently narrated and discussed conjointly. Taken together, these articles indicate that valuable information has been developed over the past 5 years concerning endothelial stability, mesenteric lymph, vascular reactivity, traumatic injuries, burn and sepsis...
February 2016: Brazilian Journal of Cardiovascular Surgery
https://www.readbyqxmd.com/read/27014695/dietary-plant-lectins-appear-to-be-transported-from-the-gut-to-gain-access-to-and-alter-dopaminergic-neurons-of-caenorhabditis-elegans-a-potential-etiology-of-parkinson-s-disease
#5
Jolene Zheng, Mingming Wang, Wenqian Wei, Jeffrey N Keller, Binita Adhikari, Jason F King, Michael L King, Nan Peng, Roger A Laine
Lectins from dietary plants have been shown to enhance drug absorption in the gastrointestinal tract of rats, be transported trans-synaptically as shown by tracing of axonal and dendritic paths, and enhance gene delivery. Other carbohydrate-binding protein toxins are known to traverse the gut intact in dogs. Post-feeding rhodamine- or TRITC-tagged dietary lectins, the lectins were tracked from gut to dopaminergic neurons (DAergic-N) in transgenic Caenorhabditis elegans (C. elegans) [egIs1(Pdat-1:GFP)] where the mutant has the green fluorescent protein (GFP) gene fused to a dopamine transport protein gene labeling DAergic-N...
2016: Frontiers in Nutrition
https://www.readbyqxmd.com/read/26878846/the-mechanism-of-high-contents-of-oil-and-oleic-acid-revealed-by-transcriptomic-and-lipidomic-analysis-during-embryogenesis-in-carya-cathayensis-sarg
#6
Jianqin Huang, Tong Zhang, Qixiang Zhang, Ming Chen, Zhengjia Wang, Bingsong Zheng, Guohua Xia, Xianyou Yang, Chunying Huang, Youjun Huang
BACKGROUND: Hickory (Carya cathayensis Sarg.) accumulates more than 70% oil and 90% unsaturated fatty acids with considerably high oleic acid in its mature embryo. The concurrent global trancriptomic and lipidomic analyses provided a framework for better understanding of glycerolipid biosynthesis and metabolism in the hickory nut. RESULTS: The synthetical regulation of numerous leading lipid-related genes harmonized with the oil accumulation and fatty acid conversion in embryo development...
2016: BMC Genomics
https://www.readbyqxmd.com/read/26453861/antioxidant-and-neuroprotective-potential-of-chitooligomers-in-caenorhabditis-elegans-exposed-to-monocrotophos
#7
T Nidheesh, Chinnu Salim, P S Rajini, P V Suresh
The objectives of this investigation were to establish the propensity of the chitooligomers (COS) to ameliorate neurodegeneration and oxidative stress in Caenorhabditis elegans induced by an organophosphorus insecticide, Monocrotophos (MCP). COS was prepared from α-chitosan by the enzymatic method using chitosanase and characterized by HPLC and electron spray ionization-TOF-(ESI-TOF)-MS. We exposed age synchronized L4 C. elegans worms (both wild type N2 and transgenic strain BZ555 (Pdat-1:GFP) to sublethal concentration of MCP (0...
January 1, 2016: Carbohydrate Polymers
https://www.readbyqxmd.com/read/26407764/a-heterocyclic-compound-ce-103-inhibits-dopamine-reuptake-and-modulates-dopamine-transporter-and-dopamine-d1-d3-containing-receptor-complexes
#8
Ajinkya Sase, Yogesh D Aher, Sivaprakasam R Saroja, Minu Karthika Ganesan, Sunetra Sase, Marion Holy, Harald Höger, Vasiliy Bakulev, Gerhard F Ecker, Thierry Langer, Harald H Sitte, Johann Leban, Gert Lubec
A series of compounds have been reported to enhance memory via the DA system and herein a heterocyclic compound was tested for working memory (WM) enhancement. 2-((benzhydrylsulfinyl)methyl)thiazole (CE-103) was synthesized in a six-step synthesis. Binding of CE-103 to the dopamine (DAT), serotonin (SERT) and norepinephrine (NET) transporters and dopamine reuptake inhibition was tested as well as blood brain permeation and a screen for GPCR targets. 60 male Sprague Dawley rats were divided into six groups: CE-103 treated 1-10 mg/kg body weight, trained (TDI) and yoked (YDI) and vehicle treated, trained (TVI) and yoked (YVI) rats...
March 2016: Neuropharmacology
https://www.readbyqxmd.com/read/26347626/the-effect-of-modafinil-on-the-rat-dopamine-transporter-and-dopamine-receptors-d1-d3-paralleling-cognitive-enhancement-in-the-radial-arm-maze
#9
Yasemin Karabacak, Sunetra Sase, Yogesh D Aher, Ajinkya Sase, Sivaprakasam R Saroja, Ana Cicvaric, Harald Höger, Michael Berger, Vasiliy Bakulev, Harald H Sitte, Johann Leban, Francisco J Monje, Gert Lubec
A series of drugs have been reported to increase memory performance modulating the dopaminergic system and herein modafinil was tested for its working memory (WM) enhancing properties. Reuptake inhibition of dopamine, serotonin (SERT) and norepinephrine (NET) by modafinil was tested. Sixty male Sprague-Dawley rats were divided into six groups (modafinil-treated 1-5-10 mg/kg body weight, trained and untrained and vehicle treated trained and untrained rats; daily injected intraperitoneally for a period of 10 days) and tested in a radial arm maze (RAM), a paradigm for testing spatial WM...
2015: Frontiers in Behavioral Neuroscience
https://www.readbyqxmd.com/read/25876170/acrylamide-induces-locomotor-defects-and-degeneration-of-dopamine-neurons-in-caenorhabditis-elegans
#10
Jia Li, Dan Li, Yongsheng Yang, Tiantian Xu, Ping Li, Defu He
Acrylamide can form in foods during the cooking process and cause multiple adverse effects. However, the neurotoxicity and mechanisms of acrylamide have not been fully elucidated. In Caenorhabditis elegans, we showed that 48 h exposure to 10-625 mg l(-1) acrylamide resulted in a significant decline in locomotor frequency of body bending, head thrashing and pharynx pumping. In addition, acrylamide exposure reduced crawling speeds and changed angles of body bending. It indicates that acrylamide induces locomotor defects, along with parkinsonian-like movement impairment, including bradykinesia and hypokinesia...
January 2016: Journal of Applied Toxicology: JAT
https://www.readbyqxmd.com/read/25753896/rnai-targeting-putative-genes-in-phosphatidylcholine-turnover-results-in-significant-change-in-fatty-acid-composition-in-crambe-abyssinica-seed-oil
#11
Rui Guan, Xueyuan Li, Per Hofvander, Xue-Rong Zhou, Danni Wang, Sten Stymne, Li-Hua Zhu
The aim of this study was to evaluate the importance of three enzymes, LPCAT, PDCT and PDAT, involved in acyl turnover in phosphatidylcholine in order to explore the possibility of further increasing erucic acid (22:1) content in Crambe seed oil. The complete coding sequences of LPCAT1-1 and LPCAT1-2 encoding lysophosphatidylcholine acyltransferase (LPCAT), PDCT1 and PDCT2 encoding phosphatidylcholine:diacylglycerol cholinephosphotransferase (PDCT), and PDAT encoding phospholipid:diacylglycerol acyltransferase (PDAT) were cloned from developing Crambe seeds...
April 2015: Lipids
https://www.readbyqxmd.com/read/25675987/eosinophilic-pustular-folliculitis-the-transition-in-sex-differences-and-interracial-characteristics-between-1965-and-2013
#12
Takashi Nomura, Mayumi Katoh, Yosuke Yamamoto, Kenji Kabashima, Yoshiki Miyachi
Eosinophilic pustular folliculitis (EPF) is characterized by a non-infectious infiltration of eosinophils in the hair follicles. It has three variants: (i) classic EPF; (ii) immunosuppression-associated EPF, which herein is subdivided into HIV-associated (IS/HIV) and non-HIV-associated (IS/non-HIV); and (iii) infancy-associated EPF (I-EPF). The rarity of EPF has hindered our understanding of this entity. To examine the characteristics of EPF, with respect to age, sex, race, and chronology, published in case reports to date, we queried PubMed using the following terms: ("eosinophilic pustular folliculitis" [All Fields] OR "eosinophilic folliculitis" [All Fields]) AND ("1965/1/1" [PDAT]: "2013/12/31" [PDAT])...
April 2015: Journal of Dermatology
https://www.readbyqxmd.com/read/25585619/genome-wide-analysis-of-phospholipid-diacylglycerol-acyltransferase-pdat-genes-in-plants-reveals-the-eudicot-wide-pdat-gene-expansion-and-altered-selective-pressures-acting-on-the-core-eudicot-pdat-paralogs
#13
Xue Pan, Fred Y Peng, Randall J Weselake
PHOSPHOLIPID:DIACYLGLYCEROL ACYLTRANSFERASE (PDAT) is an enzyme that catalyzes the transfer of a fatty acyl moiety from the sn-2 position of a phospholipid to the sn-3-position of sn-1,2-diacylglyerol, thus forming triacylglycerol and a lysophospholipid. Although the importance of PDAT in triacylglycerol biosynthesis has been illustrated in some previous studies, the evolutionary relationship of plant PDATs has not been studied in detail. In this study, we investigated the evolutionary relationship of the PDAT gene family across the green plants using a comparative phylogenetic framework...
March 2015: Plant Physiology
https://www.readbyqxmd.com/read/24730580/noncompetitive-inhibition-of-indolethylamine-n-methyltransferase-by-n-n-dimethyltryptamine-and-n-n-dimethylaminopropyltryptamine
#14
Uyen B Chu, Sevahn K Vorperian, Kenneth Satyshur, Kelsey Eickstaedt, Nicholas V Cozzi, Timur Mavlyutov, Abdol R Hajipour, Arnold E Ruoho
Indolethylamine-N-methyltransferase (INMT) is a Class 1 transmethylation enzyme known for its production of N,N-dimethyltryptamine (DMT), a hallucinogen with affinity for various serotonergic, adrenergic, histaminergic, dopaminergic, and sigma-1 receptors. DMT is produced via the action of INMT on the endogenous substrates tryptamine and S-adenosyl-l-methionine (SAM). The biological, biochemical, and selective small molecule regulation of INMT enzyme activity remain largely unknown. Kinetic mechanisms for inhibition of rabbit lung INMT (rabINMT) by the product, DMT, and by a new novel tryptamine derivative were determined...
May 13, 2014: Biochemistry
https://www.readbyqxmd.com/read/24578031/the-utilization-of-the-acyl-coa-and-the-involvement-pdat-and-dgat-in-the-biosynthesis-of-erucic-acid-rich-triacylglycerols-in-crambe-seed-oil
#15
Tomasz Furmanek, Kamil Demski, Walentyna Banaś, Richard Haslam, Jonathan Napier, Sten Stymne, Antoni Banaś
The triacylglycerol of Crambe abyssinica seeds consist of 95% very long chain (>18 carbon) fatty acids (86% erucic acid; 22:1∆13) in the sn-1 and sn-3 positions. This would suggest that C. abyssinica triacylglycerols are not formed by the action of the phospholipid:diacylglycerol acyltransferase (PDAT), but are rather the results of acyl-CoA:diacylglycerol acyltransferase (DGAT) activity. However, measurements of PDAT and DGAT activities in microsomal membranes showed that C. abyssinica has significant PDAT activity, corresponding to about 10% of the DGAT activity during periods of rapid seed oil accumulation...
April 2014: Lipids
https://www.readbyqxmd.com/read/24136468/metabolic-engineering-for-ricinoleic-acid-production-in-the-oleaginous-yeast-yarrowia-lipolytica
#16
A Beopoulos, J Verbeke, F Bordes, M Guicherd, M Bressy, A Marty, Jean-Marc Nicaud
Although there are numerous oleochemical applications for ricinoleic acid (RA) and its derivatives, their production is limited and subject to various safety legislations. In an effort to produce RA from alternative sources, we constructed a genetically modified strain of the oleaginous yeast Yarrowia lipolytica. This strain is unable to perform β-oxidation and is invalidated for the native triacylglycerol (TAG) acyltransferases (Dga1p, Dga2p, and Lro1p) and the ∆12 desaturase (Fad2p). We also expressed the Ricinus communis ∆12 hydroxylase (RcFAH12) under the control of the TEF constitutive promoter in this strain...
January 2014: Applied Microbiology and Biotechnology
https://www.readbyqxmd.com/read/24118513/phospholipid-diacylglycerol-acyltransferase-mediated-triacylglycerol-biosynthesis-is-crucial-for-protection-against-fatty-acid-induced-cell-death-in-growing-tissues-of-arabidopsis
#17
Jilian Fan, Chengshi Yan, Changcheng Xu
Phospholipid:diacylglycerol acyltransferase (PDAT) and diacylglycerol:acyl CoA acyltransferase play overlapping roles in triacylglycerol (TAG) assembly in Arabidopsis, and are essential for seed and pollen development, but the functional importance of PDAT in vegetative tissues remains largely unknown. Taking advantage of the Arabidopsis tgd1-1 mutant that accumulates oil in vegetative tissues, we demonstrate here that PDAT1 is crucial for TAG biosynthesis in growing tissues. We show that disruption of PDAT1 in the tgd1-1 mutant background causes serious growth retardation, gametophytic defects and premature cell death in developing leaves...
December 2013: Plant Journal: for Cell and Molecular Biology
https://www.readbyqxmd.com/read/23998145/economic-outcomes-in-prosthodontics
#18
REVIEW
Francesco Bassi, Alan B Carr, Ting-Ling Chang, Emad W Estafanous, Neal R Garrett, Risto-Pekka Happonen, Sreenivas Koka, Juhani Laine, Martin Osswald, Harry Reintsema, Jana Rieger, Eleni Roumanas, Thomas J Salinas, Clark M Stanford, Johan Wolfaardt
PURPOSE: A systematic literature review was conducted to identify the types of economic measures currently used in implant prosthodontics and determine the degree to which cost of care is considered in the context of any positive outcome of the care provided. MATERIALS AND METHODS: A literature search was conducted using the following set of terms plus some additional hand searching: "dental implants" (Mesh) AND ("cost") OR "maintenance" OR "healthcare policy" OR "access to care" OR "third party" OR "economic") AND (("1995/01/01"[PDat]:'2009/12/31"[PDat]) AND (Humans[Mesh]) AND (English[lang]))...
September 2013: International Journal of Prosthodontics
https://www.readbyqxmd.com/read/23824186/identification-of-a-pair-of-phospholipid-diacylglycerol-acyltransferases-from-developing-flax-linum-usitatissimum-l-seed-catalyzing-the-selective-production-of-trilinolenin
#19
Xue Pan, Rodrigo M P Siloto, Aruna D Wickramarathna, Elzbieta Mietkiewska, Randall J Weselake
The oil from flax (Linum usitatissimum L.) has high amounts of α-linolenic acid (ALA; 18:3(cis)(Δ9,12,15)) and is one of the richest sources of omega-3 polyunsaturated fatty acids (ω-3-PUFAs). To produce ∼57% ALA in triacylglycerol (TAG), it is likely that flax contains enzymes that can efficiently transfer ALA to TAG. To test this hypothesis, we conducted a systematic characterization of TAG-synthesizing enzymes from flax. We identified several genes encoding acyl-CoA:diacylglycerol acyltransferases (DGATs) and phospholipid:diacylglycerol acyltransferases (PDATs) from the flax genome database...
August 16, 2013: Journal of Biological Chemistry
https://www.readbyqxmd.com/read/23568222/using-the-candidate-gene-approach-for-detecting-genes-underlying-seed-oil-concentration-and-yield-in-soybean
#20
Mehrzad Eskandari, Elroy R Cober, Istvan Rajcan
Increasing the oil concentration in soybean seeds has been given more attention in recent years because of demand for both edible oil and biodiesel production. Oil concentration in soybean is a complex quantitative trait regulated by many genes as well as environmental conditions. To identify genes governing seed oil concentration in soybean, 16 putative candidate genes of three important gene families (GPAT: acyl-CoA:sn-glycerol-3-phosphate acyltransferase, DGAT: acyl-CoA:diacylglycerol acyltransferase, and PDAT: phospholipid:diacylglycerol acyltransferase) involved in triacylglycerol (TAG) biosynthesis pathways were selected and their sequences retrieved from the soybean database ( http://www...
July 2013: TAG. Theoretical and Applied Genetics. Theoretische und Angewandte Genetik
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