Peter H Frederiksen, Louise Linde, Emilie Gregers, Nanna L J Udesen, Ole K Helgestad, Ann Banke, Jordi S Dahl, Lisette O Jensen, Jens F Lassen, Amalie L Povlsen, Jeppe P Larsen, Henrik Schmidt, Hanne B Ravn, Jacob E Møller
AIMS: Veno-arterial extracorporeal membrane oxygenation (VA-ECMO) with profound left ventricular (LV) failure is associated with inadequate LV emptying. To unload the LV, VA-ECMO can be combined with Impella CP (ECMELLA). We hypothesized that ECMELLA improves cardiac energetics compared with VA-ECMO in a porcine model of cardiogenic shock (CS). METHODS AND RESULTS: Land-race pigs (weight 70 kg) were instrumented, including a LV conductance catheter and a carotid artery Doppler flow probe...
April 22, 2024: ESC Heart Failure