Julien Bohé, Hassane Abidi, Vincent Brunot, Amna Klich, Kada Klouche, Nicholas Sedillot, Xavier Tchenio, Jean-Pierre Quenot, Jean-Baptiste Roudaut, Nicolas Mottard, Fabrice Thiollière, Jean Dellamonica, Florent Wallet, Bertrand Souweine, Alexandre Lautrette, Jean-Charles Preiser, Jean-François Timsit, Charles-Hervé Vacheron, Ali Ait Hssain, Delphine Maucort-Boulch
PURPOSE: Hyperglycaemia is an adaptive response to stress commonly observed in critical illness. Its management remains debated in the intensive care unit (ICU). Individualising hyperglycaemia management, by targeting the patient's pre-admission usual glycaemia, could improve outcome. METHODS: In a multicentre, randomized, double-blind, parallel-group study, critically-ill adults were considered for inclusion. Patients underwent until ICU discharge either individualised glucose control by targeting the pre-admission usual glycaemia using the glycated haemoglobin A1c level at ICU admission (IC group), or conventional glucose control by maintaining glycaemia below 180 mg/dL (CC group)...
November 2021: Intensive Care Medicine