Ulrika Raue, Gwenaelle Begue, Kiril Minchev, Bozena Jemiolo, Kevin J Gries, Toby Chambers, Aliza Rubenstein, Elena Zaslavsky, Stuart C Sealfon, Todd Trappe, Scott Trappe
We investigated fast and slow muscle fiber transcriptome exercise dynamics among three groups of men: Lifelong exercisers (LLE, n=8, 74±1 y), old healthy non-exercisers (OH, n=9, 75±1 y), and young exercisers (YE, n=8, 25±1 y). Muscle biopsies were obtained pre- and 4h post-resistance exercise (3x10 knee extensions, 70% 1-RM). Fast and slow fiber size and function were assessed pre-exercise with fast and slow RNA-seq examined pre- and post-exercise. LLE fast fiber size was similar to OH, which were ~30% smaller than YE (P<0...
December 14, 2023: Journal of Applied Physiology