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https://www.readbyqxmd.com/read/29667852/determination-of-the-position-of-the-knee-at-the-time-of-an-anterior-cruciate-ligament-rupture-for-male-versus-female-patients-by-an-analysis-of-bone-bruises
#1
Kwadwo A Owusu-Akyaw, Sophia Y Kim, Charles E Spritzer, Amber T Collins, Zoë A Englander, Gangadhar M Utturkar, William E Garrett, Louis E DeFrate
BACKGROUND: The incidence of anterior cruciate ligament (ACL) ruptures is 2 to 4 times higher in female athletes as compared with their male counterparts. As a result, a number of recent studies have addressed the hypothesis that female and male patients sustain ACL injuries via different mechanisms. The efficacy of prevention programs may be improved by a better understanding of whether there are differences in the injury mechanism between sexes. Hypothesis/Purpose: To compare knee positions at the time of a noncontact ACL injury between sexes...
April 1, 2018: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/29667566/us-emergency-medical-services-fellows
#2
Brian Clemency, Christian Martin-Gill, Nicole Rall, Dipesh Patel, Jeffery Myers
IntroductionThe 2015-2016 academic year was the fourth year since the Accreditation Council for Graduate Medical Education (ACGME; Chicago, Illinois USA) accredited Emergency Medical Services (EMS) fellowships, and the first year an in-training examination was given. Soon, ACGME-accredited fellowship education will be the sole path to EMS board certification when the practice pathway closes after 2019. This project aimed to describe the current class of EMS fellows at ACGME-accredited programs and their current educational opportunities to better understand current and future needs in EMS fellowship education...
April 18, 2018: Prehospital and Disaster Medicine
https://www.readbyqxmd.com/read/29667510/air-quality-modeling-for-effective-environmental-management-in-the-mining-region
#3
Zunaira Asif, Zhi Chen, Yi Han
Air quality in the mining sector is a serious environmental concern and associated with many health issues. The air quality management in mining region has been facing many challenges due to lack of understanding of atmospheric factors and physical removal mechanism. A modeling approach called mining air dispersion model (MADM) is developed to predict air pollutants concentration in the mining region while considering the deposition effect. The model is taken into account through the planet's boundary conditions and assuming that the eddy diffusivity depends on the downwind distance...
April 18, 2018: Journal of the Air & Waste Management Association
https://www.readbyqxmd.com/read/29667370/systems-toxicology-approach-to-identifying-paracetamol-overdose
#4
Chantelle L Mason, Joseph Leedale, Sotiris Tasoulis, Ian Jarman, Daniel J Antoine, Steven D Webb
Paracetamol (acetaminophen (APAP)) is one of the most commonly used analgesics in the United Kingdom and the United States. However, exceeding the maximum recommended dose can cause serious liver injury and even death. Promising APAP toxicity biomarkers are thought to add value to those used currently and clarification of the functional relationships between these biomarkers and liver injury would aid clinical implementation of an improved APAP toxicity identification framework. The framework currently used to define an APAP overdose is highly dependent upon time since ingestion and initial dose; information that is often highly unpredictable...
April 18, 2018: CPT: Pharmacometrics & Systems Pharmacology
https://www.readbyqxmd.com/read/29667215/a-simple-signaling-rule-for-variable-life-adjusted-display-derived-from-an-equivalent-risk-adjusted-cusum-chart
#5
Philipp Wittenberg, Fah Fatt Gan, Sven Knoth
The variable life-adjusted display (VLAD) is the first risk-adjusted graphical procedure proposed in the literature for monitoring the performance of a surgeon. It displays the cumulative sum of expected minus observed deaths. It has since become highly popular because the statistic plotted is easy to understand. But it is also easy to misinterpret a surgeon's performance by utilizing the VLAD, potentially leading to grave consequences. The problem of misinterpretation is essentially caused by the variance of the VLAD's statistic that increases with sample size...
April 17, 2018: Statistics in Medicine
https://www.readbyqxmd.com/read/29666868/in-vitro-antibacterial-activity-of-oxide-and-non-oxide-bioceramics-for-arthroplastic-devices-ii-fourier-transform-infrared-spectroscopy
#6
Francesco Boschetto, Nami Toyama, Satoshi Horiguchi, Ryan M Bock, Bryan J McEntire, Tetsuya Adachi, Elia Marin, Wenliang Zhu, Osam Mazda, B Sonny Bal, Giuseppe Pezzotti
The metabolic response of Gram-positive Staphylococcus epidermidis (S. epidermidis) bacteria to bioceramic substrates was probed by means of Fourier transform infrared spectroscopy (FTIR). Oxide zirconia-toughened alumina (ZTA) and non-oxide silicon nitride (Si3N4) substrates were tested. Bacteria exposed to silica glass substrates were used as a control. S. epidermidis, a major cause of periprosthetic infections, was screened to obtain a precise time-lapse knowledge of its molecular composition and to mechanistically understand its interaction with different substrates...
April 18, 2018: Analyst
https://www.readbyqxmd.com/read/29666158/qc-art-a-tool-for-real-time-quality-control-assessment-of-mass-spectrometry-based-proteomics-data
#7
Bryan A Stanfill, Ernesto S Nakayasu, Lisa M Bramer, Allison M Thompson, Charles K Ansong, Therese Clauss, Marina A Gritsenko, Matthew E Monroe, Ronald J Moore, Daniel J Orton, Paul D Piehowski, Athena A Schepmoes, Richard D Smith, Bobbie-Jo Webb-Robertson, Thomas O Metz, The Environmental Determinants Of Diabetes In The Young Teddy Study Group
Liquid chromatography-mass spectrometry (LC-MS)-based proteomics studies of large sample cohorts can easily require from months to years to complete. Acquiring consistent, high-quality data in such large-scale studies is challenging because of normal variations in instrumentation performance over time, as well as artifacts introduced by the samples themselves, such as those due to collection, storage and processing. Existing quality control methods for proteomics data primarily focus on post-hoc analysis to remove low-quality data that would degrade downstream statistics; they are not designed to evaluate the data in near real-time, which would allow for interventions as soon as deviations in data quality are detected...
April 17, 2018: Molecular & Cellular Proteomics: MCP
https://www.readbyqxmd.com/read/29666137/the-french-prospective-multisite-registry-on-sudden-unexpected-infant-death-omin-rationale-and-study-protocol
#8
Karine Levieux, Hugues Patural, Inge Harrewijn, Elisabeth Briand Huchet, Sophie de Visme, Géraldine Gallot, Martin Chalumeau, Christèle Gras Le Guen, Matthieu Hanf
INTRODUCTION: Even after 'back-to-sleep' campaigns, sudden unexpected infant death (SUID) continues to be the leading cause of death for infants 1 month to 1 year old in developed countries, with devastating social, psychological and legal implications for families. To sustainably tackle this problem and decrease the number of SUIDs, a French SUID registry was initiated in 2015 to (1) inform prevention with standardised data, (2) understand the mechanisms leading to SUID and the contribution of the already known or newly suggested risk factors and (3) gather a multidisciplinary group of experts to coordinate and develop innovative and urgent research in the SUID area...
April 17, 2018: BMJ Open
https://www.readbyqxmd.com/read/29666129/preventing-emergency-department-ed-visits-and-hospitalisations-of-older-adults-with-cognitive-impairment-compared-with-the-general-senior-population-what-do-we-know-about-avoidable-incidents-results-from-a-scoping-review
#9
Mireille Gagnon-Roy, Benyahia Hami, Mélissa Généreux, Nathalie Veillette, Marie-Josée Sirois, Mary Egan, Véronique Provencher
OBJECTIVES: Older cognitively impaired adults present a higher risk of hospitalisation and mortality following a visit to the emergency department (ED). Better understanding of avoidable incidents is needed to prevent them and the associated ED presentations in community-dwelling adults. This study aimed to synthetise the actual knowledge concerning these incidents leading this population to ED presentation, as well as possible preventive measures to reduce them. DESIGN: A scoping review was performed according to the Arksey and O'Malley framework...
April 17, 2018: BMJ Open
https://www.readbyqxmd.com/read/29666024/social-determinants-of-self-reported-health-for-canada-s-indigenous-peoples-a-public-health-approach
#10
R Bethune, N Absher, M Obiagwu, T Qarmout, M Steeves, M Yaghoubi, R Tikoo, M Szafron, C Dell, M Farag
OBJECTIVE: In Canada, indigenous peoples suffer from a multitude of health disparities. To better understand these disparities, this study aims to examine the social determinants of self-reported health for indigenous peoples in Canada. STUDY DESIGN: This study uses data from Statistics Canada's Aboriginal Peoples Survey 2012. METHODS: Multinomial logistic regression models were used to examine how selected social determinants of health are associated with self-reported health among off-reserve First Nations and Métis peoples in Canada...
April 14, 2018: Public Health
https://www.readbyqxmd.com/read/29665928/-clinical-characteristics-treatment-and-prognosis-of-ptld-after-allogeneic-hematopoietic-stem-cell-transplantation
#11
Zhan-Xiang Liu, Wen-Rong Huang, Meng Li, Zhen-Yang Gu, Cheng-Ying Zhu, Ning Lu, Sheng Yao, Shu-Hong Wang, Fei Li, Xiao-Ning Gao, Dai-Hong Liu, Chun-Ji Gao
OBJECTIVE: To study the clinical characteristics of patients with post-transplantation lymphoproliferative disease (PTLD) after allogeneic peripheral blood hematopoietic stem cell transplantation, and to improve the understanding and diagnosis of PTLD. METHODS: The clinical data of 244 patients underwent allogeneic hematopoietic stem cell transplantation in the General Hospital of PLA from May 2014 to April 2017 were analyzed retrospectively. The follow-up time was up to November 30, 2017...
April 2018: Zhongguo Shi Yan Xue Ye Xue za Zhi
https://www.readbyqxmd.com/read/29665862/environmental-and-social-demographic-predictors-of-the-southern-house-mosquito-culex-quinquefasciatus-in-new-orleans-louisiana
#12
Imelda K Moise, Claudia Riegel, Ephantus J Muturi
BACKGROUND: Understanding the major predictors of disease vectors such as mosquitoes can guide the development of effective and timely strategies for mitigating vector-borne disease outbreaks. This study examined the influence of selected environmental, weather and sociodemographic factors on the spatial and temporal distribution of the southern house mosquito Culex quinquefasciatus Say in New Orleans, Louisiana, USA. METHODS: Adult mosquitoes were collected over a 4-year period (2006, 2008, 2009 and 2010) using CDC gravid traps...
April 17, 2018: Parasites & Vectors
https://www.readbyqxmd.com/read/29665780/writing-a-discussion-section-how-to-integrate-substantive-and-statistical-expertise
#13
REVIEW
Michael Höfler, John Venz, Sebastian Trautmann, Robert Miller
BACKGROUND: When discussing results medical research articles often tear substantive and statistical (methodical) contributions apart, just as if both were independent. Consequently, reasoning on bias tends to be vague, unclear and superficial. This can lead to over-generalized, too narrow and misleading conclusions, especially for causal research questions. MAIN BODY: To get the best possible conclusion, substantive and statistical expertise have to be integrated on the basis of reasonable assumptions...
April 17, 2018: BMC Medical Research Methodology
https://www.readbyqxmd.com/read/29665487/application-of-the-kinetic-and-isotherm-models-for-better-understanding-of-the-behaviors-of-silver-nanoparticles-adsorption-onto-different-adsorbents
#14
REVIEW
Achmad Syafiuddin, Salmiati Salmiati, Jonbi Jonbi, Mohamad Ali Fulazzaky
It is the first time to do investigation the reliability and validity of thirty kinetic and isotherm models for describing the behaviors of adsorption of silver nanoparticles (AgNPs) onto different adsorbents. The purpose of this study is therefore to assess the most reliable models for the adsorption of AgNPs onto feasibility of an adsorbent. The fifteen kinetic models and fifteen isotherm models were used to test secondary data of AgNPs adsorption collected from the various data sources. The rankings of arithmetic mean were estimated based on the six statistical analysis methods of using a dedicated software of the MATLAB Optimization Toolbox with a least square curve fitting function...
April 14, 2018: Journal of Environmental Management
https://www.readbyqxmd.com/read/29665275/effect-of-edta-and-hyaluronic-acid-on-the-viability-and-cytokine-expression-of-periodontal-ligament-fibroblasts
#15
Monique Costa Moreira França, Tânia Mara Da Silva, Gleyce Oliveira Silva, Márcia Carneiro Valera, Carlos Henrique Ribeiro Camargo
BACKGROUND/AIMS: Dental root cell proliferation following tooth avulsion has not been well researched. Understanding the effects of dry time and dentin treatment influences on cell proliferation is essential to provide evidence-based guidelines for tooth replantation. The study evaluated the viability of periodontal ligament fibroblasts (PLF) in contact with roots, submitted to surface treatments with EDTA and hyaluronic acid (HA) at different times, including to quantify inflammatory cytokines IL-6, IL-8, IL-1β and TNF-α expressed by PLF...
April 17, 2018: Dental Traumatology: Official Publication of International Association for Dental Traumatology
https://www.readbyqxmd.com/read/29664187/exercise-interventions-and-patient-beliefs-for-people-with-hip-knee-or-hip-and-knee-osteoarthritis-a-mixed-methods-review
#16
REVIEW
Michael Hurley, Kelly Dickson, Rachel Hallett, Robert Grant, Hanan Hauari, Nicola Walsh, Claire Stansfield, Sandy Oliver
BACKGROUND: Chronic peripheral joint pain due to osteoarthritis (OA) is extremely prevalent and a major cause of physical dysfunction and psychosocial distress. Exercise is recommended to reduce joint pain and improve physical function, but the effect of exercise on psychosocial function (health beliefs, depression, anxiety and quality of life) in this population is unknown. OBJECTIVES: To improve our understanding of the complex inter-relationship between pain, psychosocial effects, physical function and exercise...
April 17, 2018: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29663809/distributions-the-importance-of-the-chemist-s-molecular-view-for-biological-materials
#17
Rachel Leah Merzel, Bradford G Orr, Mark M Banaszak Holl
Characterization of materials with biological applications and assessment of physiological effects of therapeutic interventions are critical for translating research to the clinic and preventing adverse reactions. Analytical techniques typically used to characterize targeted nanomaterials and tissues rely on bulk measurement. Therefore, the resulting data represent an average structure of the sample, masking stochastic (randomly generated) distributions that are commonly present. In this Perspective, we examine almost 20 years of work our group has done in different fields to characterize and control distributions...
April 17, 2018: Biomacromolecules
https://www.readbyqxmd.com/read/29663109/changes-in-choroidal-thickness-following-trabeculectomy-and-its-correlation-with-the-decline-in-intraocular-pressure
#18
Diana Silva, Ana Sofia Lopes, Susana Henriques, Maria Lisboa, Sara Pinto, Fernando Trancoso Vaz, Isabel Prieto
PURPOSE: Evaluate whether there are significant changes in choroidal thickness following trabeculectomy, and how they relate do the decline in intraocular pressure. METHODS: This was a prospective evaluation of 28 eyes who underwent Moorfields modified trabeculectomy. The choroidal thickness was measured via OCT with enhanced depth imaging, before surgery and 1 day, 1 week and 1 month after surgery. Measurements were taken at the fovea, 1000 µm temporal to the fovea and 1000 µm nasal to the fovea...
April 16, 2018: International Ophthalmology
https://www.readbyqxmd.com/read/29662022/parental-opinions-and-attitudes-about-children-s-vaccination-safety-in-silesian-voivodeship-poland
#19
Bogumiła Braczkowska, Małgorzata Kowalska, Kamil Barański, Maksymilian Gajda, Tomasz Kurowski, Jan E Zejda
Despite mandatory vaccinations in Poland, the final decision on vaccination in children is taken by their parents or legal guardians. Understanding parents' attitudes and opinions regarding vaccinations is essential for planning and undertaking extensive and properly targeted educational actions aimed at preventing their hesitancy. In 2016, a cross-sectional study was conducted in the Silesian Voivodeship (Poland) in 11 randomly selected educational institutions. The authors' self-administered questionnaire contained 24 mixed-type questions...
April 15, 2018: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/29661752/a-novel-information-retrieval-tool-to-find-hospital-care-team-members-development-and-usability-study
#20
Kyle Morawski, Craig Monsen, Sukhjit Takhar, Adam Landman
BACKGROUND: Hospital communication among members of a patient's care team is a central part of clinical workflow and consumes a large amount of a health care provider's time. Oftentimes the complexity of hospital care leads to difficulty in finding the appropriate contact, which can lead to inefficiencies and frustration. Squire is a Web-based information retrieval app created to improve the speed and efficiency in reaching the appropriate team member during the care of a hospitalized patient...
April 16, 2018: JMIR Human Factors
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