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Understanding statistics

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https://www.readbyqxmd.com/read/28340107/association-between-the-application-of-iso-9001-2008-alone-or-in-combination-with-health-specific-standards-and-quality-related-activities-in-hungarian-hospitals
#1
Viktor Dombrádi, Orsolya Karola Csenteri, János Sándor, Sándor Godény
Objective: To investigate how International Organization for Standardization (ISO) 9001 and the Hungarian Health Care Standards (HHCS) certifications are associated with quality management, patient safety, patient rights and human resource management activities. Design: A cross-sectional study was implemented using the 2009 Hungarian hospital survey's database. Setting: Hungary. Participants: Fifty-three general hospitals were included in the statistical analysis...
March 7, 2017: International Journal for Quality in Health Care
https://www.readbyqxmd.com/read/28339791/bridg-a-domain-information-model-for-translational-and-clinical-protocol-driven-research
#2
Lauren B Becnel, Smita Hastak, Wendy Ver Hoef, Robert P Milius, MaryAnn Slack, Diane Wold, Michael L Glickman, Boris Brodsky, Charles Jaffe, Rebecca Kush, Edward Helton
Background: It is critical to integrate and analyze data from biological, translational, and clinical studies with data from health systems; however, electronic artifacts are stored in thousands of disparate systems that are often unable to readily exchange data. Objective: To facilitate meaningful data exchange, a model that presents a common understanding of biomedical research concepts and their relationships with health care semantics is required. The Biomedical Research Integrated Domain Group (BRIDG) domain information model fulfills this need...
February 26, 2017: Journal of the American Medical Informatics Association: JAMIA
https://www.readbyqxmd.com/read/28339350/the-effect-of-initial-knee-angle-on-concentric-only-squat-jump-performance
#3
Lachlan J Mitchell, Christos K Argus, Kristie-Lee Taylor, Jeremy M Sheppard, Dale W Chapman
PURPOSE: There is uncertainty as to which knee angle during a squat jump (SJ) produces maximal jump performance. Importantly, understanding this information will aid in determining appropriate ratios for assessment and monitoring of the explosive characteristics of athletes. METHOD: This study compared SJ performance across different knee angles-90º, 100º, 110º, 120º, 130º, and a self-selected depth-for jump height and other kinetic characteristics. For comparison between SJ and an unconstrained dynamic movement, participants also performed a countermovement jump from a self-selected depth...
March 24, 2017: Research Quarterly for Exercise and Sport
https://www.readbyqxmd.com/read/28338852/the-growth-of-biostatistics-and-estimation-of-cancer-risk-estimates-past-current-and-future-challenges
#4
Dale L Preston, Daniel O Stram
There has been a long process of growth and development of statistical approaches to the analysis of cancer incidence and mortality data obtained from the follow-up of radiation exposed populations. The challenges of radiation risk analysis provided impetus for innovative statistical methods, including, the inception and continued improvement of hazard rate regression methods. Key statistical contributions that improved cancer risk estimation include statistical advances pertaining to the measurement error problem...
March 2, 2017: Radiation Protection Dosimetry
https://www.readbyqxmd.com/read/28338825/modular-organization-of-residue-level-contacts-shape-the-selection-pressure-on-individual-amino-acid-sites-of-ribosomal-proteins
#5
Saurav Mallik, Sudip Kundu
Understanding the molecular evolution of macromolecular complexes in the light of their structure, assembly and stability is of central importance. Here we address how the modular organization of native molecular contacts shapes the selection pressure on individual residue sites of ribosomal complexes. The bacterial ribosomal complex is represented as a residue contact network where nodes represent amino acid/nucleotide residues and edges represent their van der Waals interactions. We find statistically overrepresented native amino acid-nucleotide contacts (OaantC, one amino acid contacts one or multiple nucleotides, inter-nucleotide contacts are disregarded)...
February 22, 2017: Genome Biology and Evolution
https://www.readbyqxmd.com/read/28338811/interventions-for-the-prevention-and-treatment-of-disability-due-to-acquired-joint-contractures-in-older-people-a-systematic-review
#6
Susanne Saal, Katrin Beutner, Julia Bogunski, Kathrin Obermüller, Martin Müller, Eva Grill, Gabriele Meyer
Background: acquired joint contractures have significant effects on quality of life and functioning. Objective: to determine the effects of interventions to prevent and treat disabilities in older people with acquired joint contractures. Methods: systematic search (last 8/2016) via Cochrane Library, PubMed, EMBASE, PEDro, CINAHL, trial registries, reference lists of retrieved articles and scientific congress pamphlets. Controlled and randomised controlled trials in English or German comparing an intervention with another intervention or standard care were included...
February 25, 2017: Age and Ageing
https://www.readbyqxmd.com/read/28337429/investigating-cardiac-motion-patterns-using-synthetic-high-resolution-3d-cardiovascular-magnetic-resonance-images-and-statistical-shape-analysis
#7
Benedetta Biffi, Jan L Bruse, Maria A Zuluaga, Hopewell N Ntsinjana, Andrew M Taylor, Silvia Schievano
Diagnosis of ventricular dysfunction in congenital heart disease is more and more based on medical imaging, which allows investigation of abnormal cardiac morphology and correlated abnormal function. Although analysis of 2D images represents the clinical standard, novel tools performing automatic processing of 3D images are becoming available, providing more detailed and comprehensive information than simple 2D morphometry. Among these, statistical shape analysis (SSA) allows a consistent and quantitative description of a population of complex shapes, as a way to detect novel biomarkers, ultimately improving diagnosis and pathology understanding...
2017: Frontiers in Pediatrics
https://www.readbyqxmd.com/read/28336449/objective-sensory-and-functional-outcomes-at-the-donor-site-following-endoscopic-assisted-sural-nerve-harvest
#8
Daniel P Butler, Kavan S Johal, Catherine E Wicks, Adriaan O Grobbelaar
BACKGROUND: The sural nerve is a common choice for a nerve graft. Understanding the potential morbidity associated with its harvest is important. In this study, we describe the objective sensory and functional outcomes associated with endoscopic sural nerve harvest from a combined paediatric and adult population. METHODS: Data were collected prospectively from patients attending for follow-up between August 2015 and January 2016, who had previously undergone an endoscopic sural nerve graft harvest...
February 28, 2017: Journal of Plastic, Reconstructive & Aesthetic Surgery: JPRAS
https://www.readbyqxmd.com/read/28336382/migration-and-infectious-diseases
#9
REVIEW
Francesco Castelli, Giorgia Sulis
BACKGROUND: Infectious diseases still represent an important cause of morbidity and mortality among foreign-born individuals. The rising migration flows towards Europe throughout the last few years are raising renewed concerns about management issues and the potential associated risk for the native population. AIMS: To discuss the health implications and challenges related to the four phases of migration, from first arrival to stable resettlement. SOURCES: Scientific literature and relevant statistical reports...
March 20, 2017: Clinical Microbiology and Infection
https://www.readbyqxmd.com/read/28335609/early-and-delayed-antiretroviral-therapy-art-result-in-comparable-reductions-in-cd8-t-cell-exhaustion-marker-expression
#10
Rachel Rutishauser, Wendy Hartogensis, Christian D Deguit, Melissa Krone, Rebecca Hoh, Rick Hecht, Christopher D Pilcher, Peter Bacchetti, Steven G Deeks, Peter W Hunt, Joseph M McCune
In untreated HIV infection, CD8+ T cell exhaustion (i.e., decreased proliferative and effector capacity) is associated with high levels of expression of co-inhibitory receptors, including PD-1, TIGIT, CD160, and 2B4. This is evident for both HIV-specific and non-HIV-specific CD8+ T cells. Antiretroviral therapy (ART) initiated during chronic infection decreases but may not completely normalize the expression of such "exhaustion markers." Compared to initiation of ART later in the course of disease, initiation soon after infection reduces some parameters of chronic inflammation and adaptive immune dysfunction...
March 23, 2017: AIDS Research and Human Retroviruses
https://www.readbyqxmd.com/read/28335602/local-structure-and-dynamics-of-water-absorbed-in-polyetherimide-a-hydrogen-bonding-anatomy
#11
Antonio De Nicola, Andrea Correa, Giuseppe Milano, Pietro La Manna, Pellegrino Musto, Giuseppe Mensitieri, Giuseppe Scherillo
Hydrogen Bonding (HB) interactions play a major role in determining the behavior of macromolecular systems absorbing water. In fact, functional and structural properties of polymer-water mixtures are affected by the amount and type of these interactions. This contribution aims at a molecular level understanding of the interactional scenario for the technologically relevant case of the polyetherimide-water system. The problem has been tackled by combining different experimental and theoretical approaches which, taken together, provide a comprehensive physical picture...
March 23, 2017: Journal of Physical Chemistry. B
https://www.readbyqxmd.com/read/28335558/modeling-the-development-of-audiovisual-cue-integration-in-speech-perception
#12
Laura M Getz, Elke R Nordeen, Sarah C Vrabic, Joseph C Toscano
Adult speech perception is generally enhanced when information is provided from multiple modalities. In contrast, infants do not appear to benefit from combining auditory and visual speech information early in development. This is true despite the fact that both modalities are important to speech comprehension even at early stages of language acquisition. How then do listeners learn how to process auditory and visual information as part of a unified signal? In the auditory domain, statistical learning processes provide an excellent mechanism for acquiring phonological categories...
March 21, 2017: Brain Sciences
https://www.readbyqxmd.com/read/28335375/assessing-the-spectral-properties-of-sunlit-and-shaded-components-in-rice-canopies-with-near-ground-imaging-spectroscopy-data
#13
Kai Zhou, Xinqiang Deng, Xia Yao, Yongchao Tian, Weixing Cao, Yan Zhu, Susan L Ustin, Tao Cheng
Monitoring the components of crop canopies with remote sensing can help us understand the within-canopy variation in spectral properties and resolve the sources of uncertainties in the spectroscopic estimation of crop foliar chemistry. To date, the spectral properties of leaves and panicles in crop canopies and the shadow effects on their spectral variation remain poorly understood due to the insufficient spatial resolution of traditional spectroscopy data. To address this issue, we used a near-ground imaging spectroscopy system with high spatial and spectral resolutions to examine the spectral properties of rice leaves and panicles in sunlit and shaded portions of canopies and evaluate the effect of shadows on the relationships between spectral indices of leaves and foliar chlorophyll content...
March 13, 2017: Sensors
https://www.readbyqxmd.com/read/28334463/a-psychometric-evaluation-of-the-chinese-version-of-the-nursing-home-survey-on-patient-safety-culture
#14
Shu-Yuan Lin, Wei Ting Tseng, Miao-Ju Hsu, Hui-Ying Chiang, Hui-Chen Tseng
AIMS AND OBJECTIVES: To test the psychometric properties of the Chinese version of the Nursing Home Survey on Patient Safety Culture scale (NHSPSC) among staff in long-term care facilities. BACKGROUND: The NHSPSC scale is a standard tool for safety culture assessment in nursing homes. Extending its application to different types of long-term care facilities and varied ethnic populations is worth pursuing. DESIGN: A national random survey. METHODS: A total of 306 managers and staff completed the Chinese version of the NHSPSC scale (C-NHSPSC) among 30 long-term care facilities in Taiwan...
March 23, 2017: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/28334457/a-bibliometric-review-of-drug-and-alcohol-research-focused-on-indigenous-peoples-of-australia-new-zealand-canada-and-the-united-states
#15
REVIEW
Anton Clifford, Anthony Shakeshaft
ISSUES: Indigenous peoples of Australia, New Zealand, Canada and the United States experience a disproportionately high burden of harms from substance misuse. Research is therefore required to improve our understanding of substance use in Indigenous populations and provide evidence on strategies effective for reducing harmful use. APPROACH: A search of 13 electronic databases for peer-reviewed articles published between 1993 and 2014 focusing on substance use and Indigenous peoples of Australia, New Zealand, Canada and the United States...
March 23, 2017: Drug and Alcohol Review
https://www.readbyqxmd.com/read/28333982/understanding-health-policy-leaders-training-needs
#16
Carey Roth Bayer, L Lerissa Smith, Renée Volny Darko, Marissa McKool, Fengxia Yan, Harry Heiman
PURPOSE: We assessed the training needs of health policy leaders and practitioners across career stages; identified areas of core content for health policy training programs; and, identified training modalities for health policy leaders. METHODS: We convened a focus group of health policy leaders at varying career stages to inform the development of the Health Policy Leaders' Training Needs Assessment tool. We piloted and distributed the tool electronically. We used descriptive statistics and thematic coding for analysis...
2017: PloS One
https://www.readbyqxmd.com/read/28333587/variational-latent-gaussian-process-for-recovering-single-trial-dynamics-from-population-spike-trains
#17
Yuan Zhao, Il Memming Park
When governed by underlying low-dimensional dynamics, the interdependence of simultaneously recorded populations of neurons can be explained by a small number of shared factors, or a low-dimensional trajectory. Recovering these latent trajectories, particularly from single-trial population recordings, may help us understand the dynamics that drive neural computation. However, due to the biophysical constraints and noise in the spike trains, inferring trajectories from data is a challenging statistical problem in general...
March 23, 2017: Neural Computation
https://www.readbyqxmd.com/read/28333396/conflicting-phylogenomic-signals-reveal-a-pattern-of-reticulate-evolution-in-a-recent-high-andean-diversification-asteraceae-astereae-diplostephium
#18
Oscar M Vargas, Edgardo M Ortiz, Beryl B Simpson
High-throughput sequencing is helping biologists to overcome the difficulties of inferring the phylogenies of recently diverged taxa. The present study analyzes the phylogenetic signal of genomic regions with different inheritance patterns using genome skimming and ddRAD-seq in a species-rich Andean genus (Diplostephium) and its allies. We analyzed the complete nuclear ribosomal cistron, the complete chloroplast genome, a partial mitochondrial genome, and a nuclear-ddRAD matrix separately with phylogenetic methods...
March 23, 2017: New Phytologist
https://www.readbyqxmd.com/read/28333195/genome-wide-genetic-analyses-highlight-mitogen-activated-protein-kinase-mapk-signaling-in-the-pathogenesis-of-endometriosis
#19
Outi Uimari, Nilufer Rahmioglu, Dale R Nyholt, Katy Vincent, Stacey A Missmer, Christian Becker, Andrew P Morris, Grant W Montgomery, Krina T Zondervan
STUDY QUESTION: Do genome-wide association study (GWAS) data for endometriosis provide insight into novel biological pathways associated with its pathogenesis? SUMMARY ANSWER: GWAS analysis uncovered multiple pathways that are statistically enriched for genetic association signals, analysis of Stage A disease highlighted a novel variant in MAP3K4, while top pathways significantly associated with all endometriosis and Stage A disease included several mitogen-activated protein kinase (MAPK)-related pathways...
February 9, 2017: Human Reproduction
https://www.readbyqxmd.com/read/28332719/rs7968606-polymorphism-of-anks1b-is-associated-with-improvement-in-the-panss-general-score-of-schizophrenia-caused-by-amisulpride
#20
Seung-Gul Kang, Ik-Seung Chee, Kwanghun Lee, Jonghun Lee
A recent genome-wide pharmacogenomics study showed that the rs7968606 single-nucleotide polymorphism (SNP) of the ankyrin repeat and sterile alpha motif domain-containing protein 1B (ANKS1B) gene approached the threshold of statistical significance. The aim of this study was to determine the association between the rs7968606 SNP of ANKS1B and the treatment response to amisulpride in schizophrenia patients. In total, 154 participants were enrolled from six university hospitals in Korea. All the subjects were interviewed before and after 6 weeks of amisulpride treatment with the aid of the positive and negative syndrome scale and the clinical global impression-severity scale...
March 23, 2017: Human Psychopharmacology
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