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femoral head necrosis

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https://www.readbyqxmd.com/read/28040082/the-physiopathology-of-avascular-necrosis-of-the-femoral-head-an-update
#1
Enrique Guerado, Enrique Caso
The physiopathology of the femoral head bone necrosis is similar for children and for adults. The disease is characterized by apoptosis of bone cells - bone marrow and bone forming cells-resulting in head collapse with a subsequent lesion of the overlying cartilage, and therefore flattening of the rounded surface shape of the head articulating with the acetabulum, provoking, eventually, secondary osteoarthritis. When the disease becomes clinically evident already destructive phenomena have occurred and collapse will eventually ensue...
December 2016: Injury
https://www.readbyqxmd.com/read/28033218/avascular-necrosis-of-the-hips-with-increased-activity-on-68ga-dotatate-pet-ct
#2
Georgios Z Papadakis, Corina Millo, Apostolos H Karantanas, Ulas Bagci, Nicholas J Patronas
Prolonged exposure to cortisol is one of the major causes of avascular bone necrosis (AVN). We report on a case of a woman with Cushing syndrome attributed to ectopic adrenocorticotropic hormone-secreting tumor who was evaluated with whole-body PET/CT study using Ga-DOTATATE. The scan showed increased activity by both femoral heads, corresponding to the margins of bilateral AVN seen on MRI. The presented data suggests AVN-induced reactive inflammatory alterations adjacent to the necrotic segment of the bone, which can be effectively targeted using radiolabeled somatostatin (SST) analogs...
December 28, 2016: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/28026725/-operative-treatment-for-saddle-shaped-femoral-heads
#3
M Burian, P Dungl, J Chomiak, M Ošťádal, R Kubeš, O Schwarz
PURPOSE OF THE STUDY A saddle-shaped deformity of the femoral head has a poor prognosis due to rapid development of secondary changes. A new method of treatment by intra-articular anteromedial wedge reduction osteotomy (AWRO) of the femoral head may preserve the hip for the future. This study was designed to ascertain that this invasive technique was safe and effective and to confirm our hypothesis that AWRO significantly improved functional and radiological parameters of the hip joint. MATERIAL AND METHODS Patients who underwent AWRO between 2010 and 2013 were enrolled in this study...
2016: Acta Chirurgiae Orthopaedicae et Traumatologiae Cechoslovaca
https://www.readbyqxmd.com/read/28018062/non-union-fracture-neck-femur-in-a-toddler-reconstructed-by-valgus-osteotomy-a-minimally-invasive-approach
#4
Amit Sharma, Anurag Tiwari, Tarun Verma, Lalit Maini
BACKGROUND: Non-union is one of the devastating complications of fracture neck of femur. Though a very rarely encountered entity in a toddler (1-3 years paediatric age group), non-united femoral neck fractures are reported in developing countries because of mismanagement by quacks and delay in referrals. For operative treatment, many different procedures have been described, including close/open reduction and internal fixation using K-wires, cannulated screws, fibula or nails. There is no evidence in the literature that one or other implant influences the rate of postoperative complications, such as avascular femoral head necrosis or coxa vara...
October 2016: Journal of Clinical Orthopaedics and Trauma
https://www.readbyqxmd.com/read/27987494/-significance-of-glucose-6-phosphate-isomerase-assay-in-early-diagnosis-of-rheumatoid-arthritis
#5
J Xu, J Liu, L Zhu, X W Zhang, Z G Li
OBJECTIVE: To explore the titer of glucose-6-phosphate isomerase (GPI) for early diagnosis of the outpatient with rheumatoid arthritis (RA) in real life, and to analyze its relationship with disease activity. METHODS: In the study, 1 051 patients with arthritis were collected in the group who had joints tender and swelling, and 90 cases of healthy people as a control group. ELISA method was used to detect the serum level of GPI, and according to clinical features and laboratory test, all the patients including 525 RA patients, the other patients including osteoarthritis (OA), 134 cases of seronegative spine joint disease (SpA), 104 cases of systemic lupus erythematosus (SLE), 31 cases of primary Sjogren syndrome (pSS), 24 cases of gout arthritis (GA), 22 cases of other connective tissue diseases (including polymyalgia rheumatica, dermatomyositis, systemic sclerosis, adult Still disease) and 46 cases of other diseases (including 165 cases of osteoporosis, avascular necrosis of the femoral head, traumatic osteomyelitis, bone and joint disease, juvenile rheumatoid arthritis, tumor)...
December 18, 2016: Beijing da Xue Xue Bao. Yi Xue Ban, Journal of Peking University. Health Sciences
https://www.readbyqxmd.com/read/27986380/evaluation-of-the-magnitude-of-hip-joint-deformation-in-subjects-with-avascular-necrosis-of-the-hip-joint-during-walking-with-and-without-scottish-rite-orthosis
#6
Mohammad Taghi Karimi, Ali Mohammadi, Mohammad Hossein Ebrahimi, Anthony McGarry
The femoral head in subjects with leg calve perthes disease (LCPD) is generally considerably deformed. It is debatable whether this deformation is due to an increase in applied loads, a decrease in bone mineral density or a change in containment of articular surfaces. The aim of this study was to determine the influence of these factors on deformation of the femoral head. Two subjects with LCPD participated in this study. Subject motion and the forces applied on the affected leg were recorded using a motion analysis system (Qualsis(TM)) and a Kistler force plate...
December 13, 2016: Medical Engineering & Physics
https://www.readbyqxmd.com/read/27928731/hip-arthroscopy-complications-regarding-surgery-and-early-postoperative-care-retrospective-study-and-review-of-literature
#7
R Seijas, O Ares, A Sallent, X Cuscó, P Álvarez-Díaz, R Tejedor, R Cugat
PURPOSE: The purpose is to describe the rate of complications in a series of hip arthroscopies performed at our center, as well as perform a systematic review of the current literature in order to compare our outcomes. METHODS: Two hundred and fifty-eight patients affected of femoroacetabular impingement and treated with hip arthroscopy have been studied. All minor and major complications were studied during the first postsurgery year. Furthermore, a systematic review was performed comparing major and minor complications with our series...
December 7, 2016: Musculoskeletal Surgery
https://www.readbyqxmd.com/read/27928615/clinical-effect-of-hyperbaric-oxygen-therapy-in-the-treatment-of-femoral-head-necrosis-a%C3%A2-systematic-review-and-meta-analysis
#8
Wei Li, Ziliang Ye, Wei Wang, Kun Wang, Lang Li, Dewei Zhao
BACKGROUND: Although many clinical studies have shown that hyperbaric oxygen (HBO) therapy in the treatment of femoral head necrosis can significantly improve clinical symptoms and patients' quality of life, this conclusion has not been systematically evaluated. Therefore, a meta-analysis was performed to systematically evaluate the clinical effect of HBO therapy in the treatment of femoral head necrosis. METHODS: PubMed, Embase, and Web of Science databases, as well as the reference lists of relevant studies published before August 2016 were systematically searched using terms related to HBO and femoral head necrosis...
December 7, 2016: Der Orthopäde
https://www.readbyqxmd.com/read/27886352/alterations-of-serum-osteocalcin-levels-in-patients-with-legg-calv%C3%A3-perthes
#9
Wen-Bo Wei, Sha-Jie Dang, Yong Li, Zong-Zhi Liu
BACKGROUND: Legg-Calvé-Perthes disease (LCPD) is a paediatric form of osteonecrosis that ultimately heals but will cause femoral head and acetabular deformities. The purpose of this study was to investigate the early serum measurement of osteocalcin in children with femoral head necrosis compared with that of healthy children. METHODS: 20 patients with LCPD (4 girls and 16 boys) and 20 healthy volunteers (5 girls and 15 boys) were enrolled. All patients did not have additional treatment...
November 14, 2016: Hip International: the Journal of Clinical and Experimental Research on Hip Pathology and Therapy
https://www.readbyqxmd.com/read/27872411/osteoporosis-in-pediatric-liver-transplantation
#10
Walid Faraj, Ghina El Nounou, Abdallah Abou Al Naaj, Nancy Nakhoul, Ali Haydar, Mohammad Khalife
Liver transplantation provides an important, often life-saving treatment for end-stage liver disease. Osteoporosis post-liver transplantation has been described in adults; however, this has not been described in the pediatric population to date. We present a case of a 13-year-old female patient who underwent an orthotopic liver transplant for cryptogenic liver cirrhosis. Her immunosuppressants were tacrolimus and prednisone. Four months posttransplant, she started complaining of bilateral lower limb pain and limping while walking, progressing to a point where she was almost immobile...
December 2016: Progress in Transplantation
https://www.readbyqxmd.com/read/27849503/causes-of-primary-total-hip-arthroplasty-in-active-duty-soldiers-are-recurrent-medical-assessments-associated-with-reduced-rates-of-secondary-osteoarthritis-in-this-population
#11
Andreas Grözinger, Andreas Musa, Sascha Gravius, Thomas M Randau, Erwin Kollig
The purpose of this study was to analyze the different causes of symptomatic osteoarthritis (OA) of the hip joint in active duty soldiers requiring a total hip arthroplasty and the hypothesis that soldiers had a reduced prevalence of secondary OA as a result of a selection process that has taken place through multiple medical assessments during their military career. We analyzed patient records from 2006 to 2012 for male patients ≤60 years with OA of the hip and indication for total hip arthroplasty in a military hospital in which civilian patients are also treated...
November 2016: Military Medicine
https://www.readbyqxmd.com/read/27847717/effectiveness-of-lower-energy-density-extracorporeal-shock-wave-therapy-in-the-early-stage-of-avascular-necrosis-of-the-femoral-head
#12
Yong Han, June-Kyung Lee, Bong-Yeon Lee, Hoi-Sung Kee, Kwang-Ik Jung, Seo-Ra Yoon
OBJECTIVE: To evaluate the effectiveness of lower energy flux density (EFD) extracorporeal shock wave therapy (ESWT) in the early stage of avascular necrosis (AVN) of the femoral head. METHODS: Nineteen patients and 30 hips were enrolled. All subjects received 4 weekly sessions of ESWT, at different energy levels; group A (n=15; 1,000 shocks/session, EFD per shock 0.12 mJ/mm(2)) and group B (n=15; 1,000 shocks/session, EFD per shock 0.32 mJ/mm(2)). We measured pain by using the visual analog scale (VAS), and disability by using the Harris hip score, Hip dysfunction and Osteoarthritis Outcome Score (HOOS), and the Western Ontario and McMaster University Osteoarthritis Index (WOMAC)...
October 2016: Annals of Rehabilitation Medicine
https://www.readbyqxmd.com/read/27846045/closed-reduction-for-developmental-dysplasia-of-the-hip-early-term-results-from-a-prospective-multicenter-cohort
#13
Wudbhav N Sankar, Alex L Gornitzky, Nicholas M P Clarke, José A Herrera-Soto, Simon P Kelley, Travis Matheney, Kishore Mulpuri, Emily K Schaeffer, Vidyadhar V Upasani, Nicole Williams, Charles T Price
BACKGROUND: Closed reduction (CR) is a common treatment for infantile developmental dysplasia of the hip. The purpose of this observational, prospective, multicenter study was to determine the early outcomes following CR. METHODS: Prospectively collected data from an international multicenter study group was analyzed for patients treated from 2010 to 2014. Baseline demographics, clinical exam, radiographic/ultrasonographic data, and history of previous orthotic treatment were assessed...
November 11, 2016: Journal of Pediatric Orthopedics
https://www.readbyqxmd.com/read/27818895/magnesium-alloy-transfected-bmscs-bmp-2-composite-in-repair-of-femoral-head-necrosis-with-assessment-of-visceral-organs
#14
Kaka A A Katiella, Zhang Yanru, Zhang Hui
BACKGROUND: This study was designed to investigate the effect of BMSCs transfected BMP-2 composite with magnesium alloy rod in the repair of the femoral head necrosis in New Zealand white rabbits. Multifactorial but mostly traumatic, osteonecrosis of the femoral head account for 10 % of the 250,000 total hip arthroplasties done annually in the United States while its prevalence in most countries in not known. However, early intervention prior to collapse is critical to successful outcomes in joint preserving procedures...
2016: SpringerPlus
https://www.readbyqxmd.com/read/27802891/reoperations-and-mortality-in-383-patients-operated-with-parallel-screws-for-garden-i-ii-femoral-neck-fractures-with-up-to-ten-years-follow-up
#15
Le Nhat Duc Do, Torbjørn Marstein Kruke, Olav A Foss, Trude Basso
INTRODUCTION: The objective of this study was to identify indications and predictors for subsequent surgeries in the same hip and to evaluate life expectancy following screw fixation of undisplaced femoral neck fractures (FNF). The study further aimed to determine the necessary follow-up time for future studies aiming to evaluate the treatment of such fractures. MATERIALS AND METHODS: This is a single-center retrospective cohort study with prospectively collected data including skeletally mature patients with undisplaced FNFs operated between 2005 and 2013...
December 2016: Injury
https://www.readbyqxmd.com/read/27795792/aseptic-necrosis-of-the-femoral-head-after-pregnancy-a-case-report
#16
Kawtar Nassar, Wafae Rachidi, Saadia Janani, Ouafa Mkinsi
A documented case of beginning aseptic necrosis of the femoral head associated with pregnancy together with a review of the literature about this rare complication of pregnancy is presented. The known risk factors of osteonecrosis are; steroid use, alcoholism, organ transplantation, especially after kidney transplant or bone marrow transplantation bone, systemic lupus erythematosus, dyslipidemia especially hypertriglyceridemia, dysbaric decompression sickness, drepanocytosis and Gaucher's disease. Among the less established factors, we mention procoagulations abnormalities, HIV infection, chemotherapy...
2016: Pan African Medical Journal
https://www.readbyqxmd.com/read/27793326/risk-factors-of-avascular-necrosis-of-the-femoral-head-and-fixation-failure-in-patients-with-valgus-angulated-femoral-neck-fractures-over-the-age-of-50-years
#17
Hyung Keun Song, Ho June Choi, Kyu Hyun Yang
INTRODUCTION: The aim of our study was to identify the risk factors for avascular necrosis of the femoral head (AVN) and fixation failure (FF) after screw osteosynthesis in patients with valgus angulated femoral neck fractures. PATIENTS AND METHODS: We conducted a retrospective study of 308 patients (mean age, 72.5 years, range, 50-97 years), with a mean follow-up of 21.4 months (range, 12-64 months). The risk for failure in treatment (FIT) associated with patient- and fracture-related factors was evaluated by logistic regression analyses...
December 2016: Injury
https://www.readbyqxmd.com/read/27790543/avascular-necrosis-of-femoral-head-in-a-child-with-beta-thalassaemia-major
#18
Adharsh Narain Thulasidhar, Sandeep Kumar, Shrikiran Aroor, Suneel Mundkur
No abstract text is available yet for this article.
September 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/27770168/-traumatic-hip-dislocation-in-a%C3%A2-6-year-old-male-child-seldom-but-demanding
#19
P Mörsdorf, A Lauer, T Histing, T Pohlemann, M Burkhardt
Traumatic hip dislocations in children are not frequent but constitute true emergencies. They require urgent reduction because of the risk of consecutive avascular necrosis of the femoral head. We report a 6-year-old boy with traumatic posterior hip dislocation on a vacation abroad. After closed reduction the day of the accident, a hip spica cast was applied and the patient was transferred home. Once home, X‑ray and CT diagnostics were completed by MRI. In future, long-term clinical and radiological investigations for avascular necrosis and growth disorders, as well as thoroughly informing the parents, should be mandatory...
October 21, 2016: Der Unfallchirurg
https://www.readbyqxmd.com/read/27767268/temporal-course-of-avascular-femoral-head-necrosis-in-patients-with-pemphigus-vulgaris
#20
Kamran Balighi, Maryam Daneshpazhooh, Nessa Aghazadeh, Vahide Saeidi, Farzam Shahpouri, Pardis Hejazi, Cheyda Chams-Davatchi
BACKGROUND AND OBJECTIVES: Pemphigus vulgaris (PV) is typically treated with systemic corticosteroids and immunosuppressive agents. Avascular necrosis (AVN) of the femoral head is a well-recognized major complication of corticosteroid therapy. The characteristics of this serious complication in PV remain unknown. PATIENTS AND METHODS: Uncontrolled, retrospective study of all PV-related AVN cases diagnosed at an Iranian autoimmune bullous disease clinic between 1985 and 2013...
October 2016: Journal der Deutschen Dermatologischen Gesellschaft, Journal of the German Society of Dermatology: JDDG
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