Yash R Shah, Hassam Ali, Angad Tiwari, David Guevara-Lazo, Natalia Nombera-Aznaran, Bhanu Siva Mohan Pinnam, Manesh Kumar Gangwani, Harishankar Gopakumar, Amir H Sohail, SriLakshmiDevi Kanumilli, Ernesto Calderon-Martinez, Geetha Krishnamoorthy, Nimish Thakral, Dushyant Singh Dahiya
Fecal microbiota transplantation (FMT) offers a potential treatment avenue for hepatic encephalopathy (HE) by leveraging beneficial bacterial displacement to restore a balanced gut microbiome. The prevalence of HE varies with liver disease severity and comorbidities. HE pathogenesis involves ammonia toxicity, gut-brain communication disruption, and inflammation. FMT aims to restore gut microbiota balance, addressing these factors. FMT's efficacy has been explored in various conditions, including HE. Studies suggest that FMT can modulate gut microbiota, reduce ammonia levels, and alleviate inflammation...
January 27, 2024: World Journal of Hepatology