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https://www.readbyqxmd.com/read/29148386/human-case-of-streptococcus-suis-disease-ontario-canada
#1
Jeisa Gomez-Torres, Asim Nimir, James Cluett, Anita Aggarwal, Sameer Elsayed, Deirdre Soares, Sarah Teatero, Yan Chen, Marcelo Gottschalk, Nahuel Fittipaldi
We report a case of Streptococcus suis human disease in Ontario, Canada, caused by a serotype 2 strain genotypically similar to those commonly isolated from pigs in North America. Initially, the isolate was misidentified as a viridans group Streptococcus. Human S. suis infections may be underdiagnosed in North America.
December 2017: Emerging Infectious Diseases
https://www.readbyqxmd.com/read/29037763/aortic-pseudoaneurysm-endocarditis-caused-by-aerococcus-viridans-a-case-report-and-literature-review
#2
Kapil Yadav, Megha Sharma, Sourabh Agarwal, Nirmanmoh Bhatia, Nitika Yadav
Aerococcus viridans is a gram positive microaerophilic lactic acid coccus which is known to cause an infection in lobsters called Gaffkaemia. Consumption of gaffekaemia affected lobsters is considered to be safe if properly cooked even though there hasn't been any research on potential transmission by this route. Though uncommon, A. viridans is capable of causing a virulent endocarditis associated with aortic valve destruction and abscess. There have been 11 worldwide reported cases of infective endocarditis, of which 6 were aortic and only one of them had aortic pseudoaneurysm (APA)...
August 26, 2017: Cardiovascular Revascularization Medicine: Including Molecular Interventions
https://www.readbyqxmd.com/read/29020360/epidemiology-clinical-features-and-outcome-of-infective-endocarditis-due-to-abiotrophia-spp-and-granulicatella-spp-report-of-76-cases-2000-2015
#3
Adrián Téllez, Juan Ambrosioni, Jaume Llopis, Juan M Pericàs, Carles Falces, Manel Almela, Cristina Garcia de la Mària, Marta Hernandez-Meneses, Bàrbara Vidal, Elena Sandoval, Eduard Quintana, David Fuster, José M Tolosana, Francesc Marco, Asunción Moreno, José M Miro
Background: Infective endocarditis (IE) caused by Abiotrophia (ABI) and Granulicatella (GRA) is poorly studied. This work aims to describe and compare the main features of ABI and GRA IE. Methods: We performed a retrospective study of 12 IE institutional cases of GRA or ABI and of 64 cases published in the literature (overall, 38 ABI and 38 GRA IE cases). Results: ABI/GRA IE represented 1.51% of IE cases in our institution between 2000-2015, compared to 0...
August 19, 2017: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/28981383/systemic-moxifloxacin-in-streptococcus-viridans-endophthalmitis
#4
Ki Yup Nam, Sang Joon Lee, Jung Yeul Kim
PURPOSE: To evaluate the effectiveness of prophylactic systemic moxifloxacin in a rabbit model of Streptococcus viridans (S. viridans) endophthalmitis. METHODS: Animals (n=60) were divided into three groups. Intravenous moxifloxacin, vancomycin, normal saline was administered to 20 animals in each group and two hours later, 10(4) colony-forming units (CFU) of S. salivarius were intravitreally injected into the left eye. Intravenous antibiotics injection was repeated on days 1, 2, and 3 after inoculation...
October 5, 2017: Ocular Immunology and Inflammation
https://www.readbyqxmd.com/read/28978934/regulation-of-antilipopolysaccharide-factors-alfpm3-and-alfpm6-in-penaeus-monodon
#5
Pitchayanan Kamsaeng, Anchalee Tassanakajon, Kunlaya Somboonwiwat
ALFPm6, a member of antimicrobial peptide in the antilipopolysaccharide factor (ALF) family from Penaeus monodon, plays important roles in shrimp immunity against pathogens. However, its antimicrobial activity and underlying mechanism have not been reported. The synthetic cyclic ALFPm6#29-52 peptide (cALFPm6#29-52) corresponding to the ALFPm6 LPS-binding domain can agglutinate and exhibited bacterial killing activity toward a Gram-negative bacterium, Escherichia coli 363 and Gram-positive bacteria, Bacillus megaterium, Aerococcus viridans, and Micrococcus luteus, with MIC values of 25-50 μM...
October 4, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28961701/zaaps-program-results-for-2015-an-activity-and-spectrum-analysis-of-linezolid-using-clinical-isolates-from-medical-centres-in-32-countries
#6
Michael A Pfaller, Rodrigo E Mendes, Jennifer M Streit, Patricia A Hogan, Robert K Flamm
Objectives: To report the linezolid in vitro activity obtained during the 2015 ZAAPS Program. Methods: In total, 7587 organisms causing documented infections were consecutively collected in 65 centres in 32 ex-USA countries. Broth microdilution susceptibility testing was performed. Isolates displaying linezolid MIC results of ≥ 4 mg/L were molecularly characterized. Results: Linezolid inhibited >99.9% of Staphylococcus aureus at ≤ 2 mg/L, with MIC50 results of 1 mg/L, regardless of methicillin resistance...
November 1, 2017: Journal of Antimicrobial Chemotherapy
https://www.readbyqxmd.com/read/28949429/predictors-of-visual-outcome-and-the-role-of-early-vitrectomy-in-streptococcal-endophthalmitis
#7
Emil D Kurniawan, John R Rocke, Sukhpal S Sandhu, Penelope J Allen
IMPORTANCE: Streptococcus endophthalmitis has devastating sequelae. This study aims to identify factors which may be targeted to optimise patient outcomes. BACKGROUND: This study investigated characteristics influencing visual outcomes, and the role of early vitrectomy. DESIGN: Retrospective observational case series of consecutive patients PARTICIPANTS: All patients with a culture-positive diagnosis of Streptococcal endophthalmitis treated at a tertiary ophthalmology referral centre between July 1997 and February 2012 METHOD: Patient records were reviewed and data collected on their presentation, examination, microbiology results, procedures and final outcome...
September 26, 2017: Clinical & Experimental Ophthalmology
https://www.readbyqxmd.com/read/28935512/analysis-of-short-and-long-term-outcomes-of-patients-with-surgically-treated-left-sided-infective-endocarditis-a-5-year-longitudinal-follow-up-study
#8
Oksana Marushchak, Holy Cole, Brett Hiebert, Evelyn Lo, Yoav Keynan, James Tam, Nasir Shaikh, Alan H Menkis, Rakesh C Arora, Pallav Shah
This study aims to analyze survival, repeat hospitalization, and risk factors for surgically treated left-sided endocarditis. Retrospective review of all 166 (114 native and 52 prosthetic) patients operated between January 2004 and March 2015 was performed. Long-term survival and repeat hospitalization data for 134 of 166 patients were obtained via linked clinical databases with the Manitoba Centre for Health Policy. Kaplan-Meier estimates of survival and hospital readmission and Cox multivariable regression analysis of factors influencing outcomes were performed...
August 23, 2017: Seminars in Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/28838838/microbiology-and-antibiotic-sensitivity-of-head-and-neck-space-infections-of-odontogenic-origin-differences-in-inpatient-and-outpatient-management
#9
Nils Heim, Anton Faron, Valentin Wiedemeyer, Rudolf Reich, Markus Martini
INTRODUCTION: The microbial flora of infections of the orofacial region of odontogenic origin is typically polymicrobial. Shortly after mass production of the first antibiotics, antibiotic resistant microorganisms were observed. METHODS: A 28-months retrospective study evaluated hospital records of 107 patients that were treated for head and neck infections of odontogenic origin. All patients underwent surgical incision and drainage. RESULTS: There were 65 male (61%) and 42 female (39%) patients ranging in age from 5 to 91 years, with a mean age of 48 years (SD = 21)...
October 2017: Journal of Cranio-maxillo-facial Surgery
https://www.readbyqxmd.com/read/28828970/antimicrobial-resistance-patterns-of-the-gram-positive-bacteria-isolated-from-children-with-bloodstream-infection-in-an-iranian-referral-hospital-a-6-year-study
#10
Setareh Mamishi, Babak Pourakbari, Shima Mahmoudi, Mina Moradzadeh, Masoumeh Mahzari, Mohammad TaghiHaghi Ashtiani, Parin Tanzifi
BACKGROUND: Bloodstream infections (BSI) are considered as a serious cause of morbidity and mortality in pediatricschildren. The aim of this study was to depict report the common Gram-positive bacteria (GPB) responsible for bloodstream infections in children and determine their antimicrobial resistance patterns in Children Medical Center Hospital (CMC), ) Hospital, Tehran, Iran. METHODS: This retrospective study was conducted within a six-year period (March 2011 to September 2016) for pediatric patients with BSI...
August 21, 2017: Infectious Disorders Drug Targets
https://www.readbyqxmd.com/read/28817362/in-response-to-microbial-diversity-in-milk-of-women-with-mastitis-potential-role-of-coagulase-negative-staphylococci-viridans-group-streptococci-and-corynebacteria
#11
Meabh Cullinane, Lisa H Amir
No abstract text is available yet for this article.
August 1, 2017: Journal of Human Lactation: Official Journal of International Lactation Consultant Association
https://www.readbyqxmd.com/read/28782216/temporal-changes-in-neutropenic-blood-culture-isolates-and-disease-associations-a-single-centre-series-of-1139-episodes
#12
Nathanael Lucas, Michael Humble, Dalice Sim, Michelle Balm, John Carter, Robert Weinkove
Neutropenic infections are life-threatening and require empiric antibiotic treatment. We examined 1139 blood culture isolates from our institution over a 36-year period from neutropenic patients to examine temporal trends and disease associations. Positive associations were found between viridans streptococci and acute myeloid leukaemia, coagulase negative staphylococci and acute lymphoblastic leukaemia and Pseudomonas aeruginosa and indolent B-cell malignancies.
August 2017: Internal Medicine Journal
https://www.readbyqxmd.com/read/28776170/viridans-group-streptococci-bloodstream-infections-in-neutropenic-adult-patients-with-hematologic-malignancy-single-center-experience
#13
J Radocha, P Paterová, A Zavřelová, B Víšek, F Gabalec, H Žemličková, P Žák
Viridans group streptococci bloodstream infections (VGS BSI) remain a significant cause of mortality and morbidity in patients with severe neutropenia. The goal of our study was to evaluate clinical course and microbiological susceptibility of VGS BSI at our center. Retrospective analysis of all microbiologically documented bloodstream infections caused by VGS during the 9-year time period (from January 2006 until December 2014) was carried out. Only patients with severe neutropenia (< 500/μL) were included in the study...
August 3, 2017: Folia Microbiologica
https://www.readbyqxmd.com/read/28756939/bacteriology-of-peritonsillar-abscess-the-changing-trend-and-predisposing-factors
#14
Yi-Wen Tsai, Yu-Hsi Liu, Hsing-Hao Su
INTRODUCTION: Peritonsillar abscess is the most common deep neck infection. The infectious microorganism may be different according to clinical factors. OBJECTIVE: To identify the major causative pathogen of peritonsillar abscess and investigate the relationship between the causative pathogen, host clinical factors, and hospitalization duration. METHODS: This retrospective study included 415 hospitalized patients diagnosed with peritonsillar abscess who were admitted to a tertiary medical center from June 1990 to June 2013...
July 17, 2017: Brazilian Journal of Otorhinolaryngology
https://www.readbyqxmd.com/read/28737874/-brain-abscess-in-children-ten-years-of-experience-in-a-third-level-pediatric-hospital
#15
Martín Brizuela, Guadalupe Pérez, Soledad Martiren, Ana N Varela Baino, Carola Cedillo, Silvina Ruvinsky, Carolina Epelbaum, Adela Isasmendi, Mirta Litterio, José L Pinheiro, Rosa Bologna
Brain abscess is a focal infection that occurs with a frequency of 0.3-1.3 cases per 100,000 people/year. We describe the epidemiology, clinical and microbiology characteristics of 38 children diagnosed with brain abscess hospitalized between 4/1/2005 and 12/31/2015 at Hospital de Pediatría "Prof. Dr. Juan P. Garrahan" in Buenos Aires City. Twenty-four patients were male. The median age was 132 months. Predisposing factors were detected in 25 children. The median evolution from onset of symptoms to the visit was 7 days...
August 1, 2017: Archivos Argentinos de Pediatría
https://www.readbyqxmd.com/read/28735053/activity-of-dalbavancin-tested-against-gram-positive-clinical-isolates-causing-skin-and-skin-structure-infections-in-paediatric-patients-from-us-hospitals-2014-2015
#16
Michael A Pfaller, Rodrigo E Mendes, Helio S Sader, Mariana Castanheira, Robert K Flamm
OBJECTIVES: This study provides an in vitro analysis of dalbavancin activity against isolates causing skin and skin-structure infections (SSSIs) in children. METHODS: A total of 770 Staphylococcus aureus, 167 β-haemolytic streptococci (BHS), 42 coagulase-negative staphylococci (CoNS), 25 Enterococcus faecalis and 13 viridans group streptococci (VGS) were collected from children (<18years old) in the USA (2014-2015). RESULTS: Dalbavancin had MIC50/90 values of 0...
July 19, 2017: Journal of Global Antimicrobial Resistance
https://www.readbyqxmd.com/read/28727951/in-vitro-activity-of-telavancin-against-clinically-important-gram-positive-pathogens-from-69-u-s-medical-centers-2015-potency-analysis-by-u-s-census-divisions
#17
Michael A Pfaller, Helio S Sader, Robert K Flamm, Mariana Castanheira, Jennifer I Smart, Rodrigo E Mendes
A total of 8,072 gram-positive isolates collected from 69 medical centers among all 9 U.S. Census Divisions during the 2015 SENTRY Antimicrobial Surveillance Program were included. Telavancin had minimal inhibitory concentration (MIC)50 and MIC90 values of 0.03/0.06 μg/mL, respectively, against methicillin-susceptible (MSSA) and methicillin-resistant Staphylococcus aureus (MRSA). Similar activity was also observed among coagulase-negative staphylococci (MIC50/90, 0.03/0.06 μg/ml; 100.0% inhibited by ≤0...
September 2017: Microbial Drug Resistance: MDR: Mechanisms, Epidemiology, and Disease
https://www.readbyqxmd.com/read/28683646/bloodstream-infections-in-acute-myeloid-leukemia-patients-treated-according-to-the-finnish-leukemia-group-aml-2003-protocol-a-prospective-nationwide-study
#18
Aarne Kolonen, Marjatta Sinisalo, Reetta Huttunen, Jaana Syrjänen, Janne Aittoniemi, Heini Huhtala, Marja Sankelo, Hannele Rintala, Riikka Räty, Esa Jantunen, Tapio Nousiainen, Marjaana Säily, Marjut Kauppila, Maija Itälä-Remes, Hanna Ollikainen, Auvo Rauhala, Pirjo Koistinen, Erkki Elonen
BACKGROUND: Infections greatly influence the outcome of acute myeloid leukemia (AML) patients receiving intensive treatment. The aim of this study was to establish the incidence, microbial etiology, risk factors and prognosis of bloodstream infections (BSIs) in patients with AML and compare the results with the previous treatment protocol (AML-92). METHODS: Registery data were gathered prospectively from 357 patients aged 16-65 years recruited on the AML-2003 treatment protocol between November 2003 and November 2011 during different treatment cycles...
July 6, 2017: Infectious Diseases
https://www.readbyqxmd.com/read/28681536/mycotic-aneurysm-of-the-root-of-left-subclavian-artery-associated-with-aortic-coarctation-discovered-by-echocardiography
#19
Ming-Dan Deng, Xin Wei, Wen Zhang, Hong Tang
A 16-year-old girl was admitted with a 7-month history of recurrent fever, weight loss of 5 kg, and general poor health status. Blood culture was positive with Streptococcus viridans. Transthoracic echocardiography established an aneurysm of the root of left subclavian artery, associated with an aortic coarctation just before the origin of the left subclavian artery with a velocity of 4.8 cm/s. Three-dimensional echocardiography demonstrated the entire inner structure of the aneurysm. Computed tomography reconstruction confirmed the presence of aortic coarctation and mycotic aneurysm, it also revealed an aberrant right subclavian artery...
July 6, 2017: Echocardiography
https://www.readbyqxmd.com/read/28681361/top-down-lesa-mass-spectrometry-protein-analysis-of-gram-positive-and-gram-negative-bacteria
#20
Klaudia I Kocurek, Leanne Stones, Josephine Bunch, Robin C May, Helen J Cooper
We have previously shown that liquid extraction surface analysis (LESA) mass spectrometry (MS) is a technique suitable for the top-down analysis of proteins directly from intact colonies of the Gram-negative bacterium Escherichia coli K-12. Here we extend the application of LESA MS to Gram-negative Pseudomonas aeruginosa PS1054 and Gram-positive Staphylococcus aureus MSSA476, as well as two strains of E. coli (K-12 and BL21 mCherry) and an unknown species of Staphylococcus. Moreover, we demonstrate the discrimination between three species of Gram-positive Streptococcus (Streptococcus pneumoniae D39, and the viridans group Streptococcus oralis ATCC 35037 and Streptococcus gordonii ATCC35105), a recognized challenge for matrix-assisted laser desorption ionization time-of-flight MS...
October 2017: Journal of the American Society for Mass Spectrometry
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