Natasha G Boyes, Michael D Nelson, Alberto Palmero-Canton, Adam M S Luchkanych, Rafique Khan, Idris Bare, Tony Haddad, Sherif Abdalla, Rory A Marshall, Cameron J Morse, Alexander Zhai, Haissam Haddad, Darcy Marciniuk, Geoffrey Karjala, T Dylan Olver, Corey R Tomczak
INTRODUCTION: Heart failure with reduced ejection fraction (HFrEF) exhibits exaggerated sympathoexcitation and altered cardiac and vascular responses to muscle metaboreflex activation (MMA). However, left ventricular (LV) responses to MMA are not well studied in patients with HFrEF. The purpose of this study was to examine LV function during MMA using cardiac magnetic resonance imaging (MRI) in patients with HFrEF. METHODS: Thirteen patients with HFrEF and 18 healthy age-matched controls underwent cardiac MRI during rest and MMA...
June 22, 2023: Journal of Applied Physiology