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Kevin Bihan, Qin Lu, Manon Enjalbert, Maxime Apparuit, Olivier Langeron, Jean-Jacques Rouby, Christian Funck-Brentano, Noel Zahr
BACKGROUND: Colistin is a polypeptide antibiotic from the polymyxin E group used for the treatment of infections caused by multidrug resistant gram-negative bacteria. The main constituents, accounting for approximately 85% of this mixture, are colistinA (polymyxin E1) and colistin B (polymyxin E2). The aim of this study was to develop and validate new and fast methods of quantification of colistin A&B and its precursors (CMS A&B) by Liquid Chromatography-tandem Mass Spectrometry (UPLC-MS) in plasma and urine with short pre-treatment and run times...
September 27, 2016: Therapeutic Drug Monitoring
Marcela Nastro, Néstor Carranza, Fernando Aprigliano, Elsa Saposnik, Claudia Barberis, Susana García, Carlos Vay, Carlos H Rodríguez, Angela Famiglietti
Se estudiaron 64 aislamientos de K. pneumoniae resistentes a colistina recuperados de materiales clínicos de 57 pacientes atendidos entre los años 2010 y 2012 en el Hospital de Clínicas José de San Martín, Universidad de Buenos Aires, con el objetivo de describir las características microbiológicas y epidemiológicas y los factores relacionados con la emergencia de estos aislamientos. Se incluyeron en el estudio 54 aislamientos de K. pneumoniae sensibles a colistina contemporáneos a los aislamientos resistentes...
July 2013: Revista Argentina de Microbiología
R Julve, E Rovira, A Belda, J Prat, R Escoms, A Albert, F Gonzalvo
OBJECTIVE: Stenotrophomonas maltophilia (SM) is a gram-negative bacillus whose incidence like nosocomial pathogen has been incremented in the last years, especially in immunocompromised patients, subjected to invasive procedures and those receiving broad-spectrum antimicrobial therapy. METHOD: We report 15 isolations of SM between 1994-1996. RESULTS: The criteria for SM infection were fulfilled by 9 patients (60%), and 6 patients (40%) were colonized...
September 1998: Anales de Medicina Interna: Organo Oficial de la Sociedad Española de Medicina Interna
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