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Colistina

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https://www.readbyqxmd.com/read/27684296/determination-of-colistin-and-colistimethate-levels-in-human-plasma-and-urine-by-high-performance-liquid-chromatography-tandem-mass-spectrometry
#1
Kevin Bihan, Qin Lu, Manon Enjalbert, Maxime Apparuit, Olivier Langeron, Jean-Jacques Rouby, Christian Funck-Brentano, Noël Zahr
BACKGROUND: Colistin is a polypeptide antibiotic from the polymyxin E group used for the treatment of infections caused by multidrug-resistant gram-negative bacteria. The main constituents, accounting for approximately 85% of this mixture, are colistin A (polymyxin E1) and colistin B (polymyxin E2). The aim of this study was to develop and validate new and fast methods of quantification of colistin A and B and its precursors [colistin methanesulfonate sodium (CMS) A and B] by ultraperformance liquid chromatography-tandem mass spectrometry in plasma and urine with short pretreatment and run times...
December 2016: Therapeutic Drug Monitoring
https://www.readbyqxmd.com/read/24125007/-emergence-of-colistin-resistant-klebsiella-pneumoniae-microbiological-and-epidemiological-characterization-of-the-isolates-producing-and-non-producing-kpc-type-carbapenemase
#2
Marcela Nastro, Néstor Carranza, Fernando Aprigliano, Elsa Saposnik, Claudia Barberis, Susana García, Carlos Vay, Carlos H Rodríguez, Angela Famiglietti
Se estudiaron 64 aislamientos de K. pneumoniae resistentes a colistina recuperados de materiales clínicos de 57 pacientes atendidos entre los años 2010 y 2012 en el Hospital de Clínicas José de San Martín, Universidad de Buenos Aires, con el objetivo de describir las características microbiológicas y epidemiológicas y los factores relacionados con la emergencia de estos aislamientos. Se incluyeron en el estudio 54 aislamientos de K. pneumoniae sensibles a colistina contemporáneos a los aislamientos resistentes...
July 2013: Revista Argentina de Microbiología
https://www.readbyqxmd.com/read/10079538/-clinical-manifestations-of-stenotrophomas-xanthomonas-maltophilia-infection
#3
R Julve, E Rovira, A Belda, J Prat, R Escoms, A Albert, F Gonzalvo
OBJECTIVE: Stenotrophomonas maltophilia (SM) is a gram-negative bacillus whose incidence like nosocomial pathogen has been incremented in the last years, especially in immunocompromised patients, subjected to invasive procedures and those receiving broad-spectrum antimicrobial therapy. METHOD: We report 15 isolations of SM between 1994-1996. RESULTS: The criteria for SM infection were fulfilled by 9 patients (60%), and 6 patients (40%) were colonized...
September 1998: Anales de Medicina Interna: Organo Oficial de la Sociedad Española de Medicina Interna
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