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https://www.readbyqxmd.com/read/27905896/the-impact-of-medical-tourism-on-colorectal-screening-among-korean-americans-a-community-based-cross-sectional-study
#1
Linda K Ko, Victoria M Taylor, Jihye Yoon, Wade K Copeland, Joo Ha Hwang, Eun Jeong Lee, John Inadomi
BACKGROUND: Colorectal cancer (CRC) remains the most commonly diagnosed cancer among Korean Americans (KAs) in part due to low screening rates. Recent studies suggest that some KA patients engage in medical tourism and receive medical care in their home country. The impact of medical tourism on CRC screening is unknown. The purpose of this paper was to 1) investigate the frequency of medical tourism, 2) examine the association between medical tourism and CRC screening, and 3) characterize KA patients who engage in medical tourism...
December 1, 2016: BMC Cancer
https://www.readbyqxmd.com/read/27903036/cannabis-use-and-its-associated-disorders-clinical-care
#2
Jan Copeland
BACKGROUND: Globally, cannabis is the most widely used and variably regulated illicit drug. The rates of use appeared to be stable in Australia at the time of the 2013 National Drug Strategy Household Survey, but levels of cannabis use disorder are rising and treatment seeking is increasing internationally. OBJECTIVE: This article describes the prevalence of cannabis use, associated disorders (eg harms with early and frequent use), and information on assessment and management...
December 2016: Australian Family Physician
https://www.readbyqxmd.com/read/27899479/a-formative-review-of-physical-activity-interventions-for-minority-ethnic-populations-in-england
#3
E Such, S Salway, R Copeland, S Haake, S Domone, S Mann
BACKGROUND: Physical activity (PA) levels are lower among some UK Black and minority ethnic (BME) groups than the majority White British population and a variety of tailored interventions have emerged. This study documents the characteristics and logic of local adaptations, a vital first step in evaluating such innovations. METHODS: An English PA data set was examined to identify and characterize PA programmes focussed on BME populations. Three case studies were conducted, employing documentary analysis and qualitative interviews...
November 29, 2016: Journal of Public Health
https://www.readbyqxmd.com/read/27893534/clinical-predictors-of-positive-postoperative-blood-cultures
#4
Libby R Copeland-Halperin, Joshua Stodghill, Erica Emery, Amber W Trickey, Jonathan Dort
OBJECTIVE: To define clinical features of surgical patients in whom postoperative blood cultures are likely to identify pathogens. BACKGROUND: Bacteremia is a worrisome postoperative complication and blood cultures (BCx) are routinely used for evaluation of postoperative bacteremia, but are costly and not always diagnostic. Better methods are needed to select patients in whom BCx identify pathogens. METHODS: We reviewed records of patients ≥18 years old with BCx drawn ≤10 days after surgery in 2013 seeking independent predictors of positive cultures by simple and multiple logistic regression models with statistical significance at α = 0...
November 23, 2016: Annals of Surgery
https://www.readbyqxmd.com/read/27892245/a-minister-s-average-pay-is-nearly-three-times-that-of-a-nurse
#5
Jamie Copeland
The government argues that nurses' pay is already above the national average and that many of us receive pay progression increments.
November 23, 2016: Nursing Standard
https://www.readbyqxmd.com/read/27891783/population-based-microcephaly-surveillance-in-the-united-states-2009-to-2013-an-analysis-of-potential-sources-of-variation
#6
Janet D Cragan, Jennifer L Isenburg, Samantha E Parker, C J Alverson, Robert E Meyer, Erin B Stallings, Russell S Kirby, Philip J Lupo, Jennifer S Liu, Amanda Seagroves, Mary K Ethen, Sook Ja Cho, MaryAnn Evans, Rebecca F Liberman, Jane Fornoff, Marilyn L Browne, Rachel E Rutkowski, Amy E Nance, Marlene Anderka, Deborah J Fox, Amy Steele, Glenn Copeland, Paul A Romitti, Cara T Mai
BACKGROUND: Congenital microcephaly has been linked to maternal Zika virus infection. However, ascertaining infants diagnosed with microcephaly can be challenging. METHODS: Thirty birth defects surveillance programs provided data on infants diagnosed with microcephaly born 2009 to 2013. The pooled prevalence of microcephaly per 10,000 live births was estimated overall and by maternal/infant characteristics. Variation in prevalence was examined across case finding methods...
November 2016: Birth Defects Research. Part A, Clinical and Molecular Teratology
https://www.readbyqxmd.com/read/27891655/a-comparison-of-parent-and-childcare-provider-s-attitudes-and-perceptions-about-preschoolers-physical-activity-and-outdoor-time
#7
P S Tandon, B E Saelens, K A Copeland
BACKGROUND: Young children depend on adult caregivers to provide opportunities for physical activity. Research has focused on barriers and facilitators to children's physical activity while in childcare, but parental influences remain largely unknown. This study examines parent's attitudes about preschoolers' physical activity and outdoor time, compares them with those of childcare providers and determines the association between parental attitudes and preschoolers' measured activity...
November 28, 2016: Child: Care, Health and Development
https://www.readbyqxmd.com/read/27885466/molecular-epidemiology-and-multilocus-sequence-analysis-of-potentially-zoonotic-giardia-spp-from-humans-and-dogs-in-jamaica
#8
Mellesia F Lee, Paul Cadogan, Sarah Eytle, Sonia Copeland, Julia Walochnik, John F Lindo
Giardia spp. are the causative agents of intestinal infections in a wide variety of mammals including humans and companion animals. Dogs may be reservoirs of zoonotic Giardia spp.; however, the potential for transmission between dogs and humans in Jamaica has not been studied. Conventional PCR was used to screen 285 human and 225 dog stool samples for Giardia targeting the SSU rDNA gene followed by multilocus sequencing of the triosephosphate isomerase (tpi), glutamate dehydrogenase (gdh), and β-giardin (bg) genes...
November 25, 2016: Parasitology Research
https://www.readbyqxmd.com/read/27884514/less-radical-surgery-for-early-stage-cervical-cancer-can-conization-specimens-help-identify-patients-at-low-risk-for-parametrial-involvement
#9
Blair Smith, Georgia A McCann, Gary Phillips, Floor J Backes, David M O'Malley, David E Cohn, Jeffrey M Fowler, Larry J Copeland, Ritu Salani
OBJECTIVE: Radical hysterectomy for cervical cancer is associated with increased morbidity over an extrafascial hysterectomy. The goal of this study was to determine incidence of and risk factors for parametrial involvement (PI) based on conization specimen (CS) and to potentially identify candidates for less radical surgery. METHODS: Patients with FIGO IA2-IIA cervical cancer treated with radical hysterectomy and pelvic lymph node dissection (RH) from 2000 to 2010 were retrospectively identified...
November 21, 2016: Gynecologic Oncology
https://www.readbyqxmd.com/read/27876541/diagnostic-performance-of-a-biomarker-panel-as-a-negative-predictor-for-acute-appendicitis-in-adult-emergency-department-patients-with-abdominal-pain
#10
David S Huckins, Karen Copeland, Wesley Self, Cheryl Vance, Phyllis Hendry, Keith Borg, Joseph Gogain
OBJECTIVES: Evaluate the diagnostic accuracy of the APPY1TM biomarker panel, previously described for use in pediatric patients, for identifying adult ED patients with abdominal pain who are at low risk of acute appendicitis. METHODS: This study prospectively enrolled subjects >18years of age presenting to seven U.S. emergency departments with <72hours of abdominal pain suggesting possible acute appendicitis. The APPY1 panel was performed on blood samples drawn from each patient at the time of initial evaluation and results were correlated with the final diagnosis either positive or negative for acute appendicitis...
November 11, 2016: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/27870987/single-arm-trial-of-the-second-version-of-an-acceptance-commitment-therapy-smartphone-application-for-smoking-cessation
#11
Jonathan B Bricker, Wade Copeland, Kristin E Mull, Emily Y Zeng, Noreen L Watson, Katrina J Akioka, Jaimee L Heffner
BACKGROUND: The first randomized trial of a smartphone application (app) for adult smoking cessation (SmartQuit 1.0) revealed key features that predict cessation. These findings guided the revision of this Acceptance & Commitment Therapy (ACT)-based application (SmartQuit 2.0), which was primarily tested to examine participant receptivity, short-term cessation and reduction, and the relationship between program completion, smoking cessation and reduction. Secondarily, outcomes were descriptively compared with the SmartQuit1...
November 4, 2016: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/27865061/setting-spatial-conservation-priorities-despite-incomplete-data-for-characterizing-metapopulations
#12
A H Fullerton, S Anzalone, P Moran, D M Van Doornik, T Copeland, R W Zabel
Management of spatially structured species poses unique challenges. Despite a strong theoretical foundation, practitioners rarely have sufficient empirical data to evaluate how populations interact. Rather, assumptions about connectivity and source-sink dynamics are often based on incomplete, extrapolated, or modeled data, if such interactions are even considered at all. Therefore, it has been difficult to evaluate whether spatially structured species are meeting conservation goals. We evaluated how estimated metapopulation structure responded to estimates of population sizes and dispersal probabilities and to the set of populations included...
December 2016: Ecological Applications: a Publication of the Ecological Society of America
https://www.readbyqxmd.com/read/27853410/corrigenda-roques-a-copeland-rs-soldati-l-denux-o-auger-rozenberg-m-a-2016-megastigmus-seed-chalcids-hymenoptera-torymidae-radiated-much-more-on-angiosperms-than-previously-considered-i-description-of-8-new-species-from-kenya-with-a-key-to-the-females-of-eastern
#13
https://www.readbyqxmd.com/read/27852226/genomic-differentiation-among-wild-cyanophages-despite-widespread-horizontal-gene-transfer
#14
Ann C Gregory, Sergei A Solonenko, J Cesar Ignacio-Espinoza, Kurt LaButti, Alex Copeland, Sebastian Sudek, Ashley Maitland, Lauren Chittick, Filipa Dos Santos, Joshua S Weitz, Alexandra Z Worden, Tanja Woyke, Matthew B Sullivan
BACKGROUND: Genetic recombination is a driving force in genome evolution. Among viruses it has a dual role. For genomes with higher fitness, it maintains genome integrity in the face of high mutation rates. Conversely, for genomes with lower fitness, it provides immediate access to sequence space that cannot be reached by mutation alone. Understanding how recombination impacts the cohesion and dissolution of individual whole genomes within viral sequence space is poorly understood across double-stranded DNA bacteriophages (a...
November 16, 2016: BMC Genomics
https://www.readbyqxmd.com/read/27851162/1526-perioperative-organ-dysfunction-predicts-mortality-in-critically-ill-patients
#15
Curtis Copeland, Andrew Young, Tristan Grogan, Eilon Gabel, Anahat Dhillon, Sadeq Quraishi, Vadim Gudzenko
No abstract text is available yet for this article.
December 2016: Critical Care Medicine
https://www.readbyqxmd.com/read/27849608/transposon-mutagenesis-identifies-genes-that-cooperate-with-mutant-pten-in-breast-cancer-progression
#16
Roberto Rangel, Song-Choon Lee, Kenneth Hon-Kim Ban, Liliana Guzman-Rojas, Michael B Mann, Justin Y Newberg, Takahiro Kodama, Leslie A McNoe, Luxmanan Selvanesan, Jerrold M Ward, Alistair G Rust, Kuan-Yew Chin, Michael A Black, Nancy A Jenkins, Neal G Copeland
Triple-negative breast cancer (TNBC) has the worst prognosis of any breast cancer subtype. To better understand the genetic forces driving TNBC, we performed a transposon mutagenesis screen in a phosphatase and tensin homolog (Pten) mutant mice and identified 12 candidate trunk drivers and a much larger number of progression genes. Validation studies identified eight TNBC tumor suppressor genes, including the GATA-like transcriptional repressor TRPS1 Down-regulation of TRPS1 in TNBC cells promoted epithelial-to-mesenchymal transition (EMT) by deregulating multiple EMT pathway genes, in addition to increasing the expression of SERPINE1 and SERPINB2 and the subsequent migration, invasion, and metastasis of tumor cells...
November 14, 2016: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/27845591/drug-target-interaction-kinetics-underutilized-in-drug-optimization
#17
Robert A Copeland
No abstract text is available yet for this article.
November 15, 2016: Future Medicinal Chemistry
https://www.readbyqxmd.com/read/27836701/synchronous-tumors-of-the-cerebellopontine-angle
#18
Christopher S Graffeo, Avital Perry, William R Copeland, Caterina Giannini, Brian A Neff, Colin L W Driscoll, Michael J Link
BACKGROUND: Synchronous tumors of the cerebellopontine angle (CPA) are exceedingly rare, and inconsistently described. We report two cases of contiguous vestibular schwannoma (VS) and meningioma, and perform a systematic literature review of all multiple CPA tumors. METHODS: Retrospective chart review and systematic literature review RESULTS: A 64-year-old woman and a 42-year-old man presented with symptoms referable to the CPA. MR imaging in both revealed two separate contiguous tumors...
November 8, 2016: World Neurosurgery
https://www.readbyqxmd.com/read/27834535/a-retrospective-cohort-study-of-comorbidity-trajectories-associated-with-traumatic-brain-injury-in-veterans-of-the-iraq-and-afghanistan-wars
#19
Mary Jo Pugh, Erin P Finley, Chen-Pin Wang, Laurel A Copeland, Carlos A Jaramillo, Alicia A Swan, Christine A Elnitsky, Luci K Leykum, Eric M Mortensen, Blessen A Eapen, Polly H Noel, Jacqueline A Pugh
OBJECTIVES: To identify and validate trajectories of comorbidity associated with traumatic brain injury in male and female Iraq and Afghanistan war Veterans (IAV). METHODS: Derivation and validation cohorts were compiled of IAV who entered the Department of Veterans Affairs (VA) care and received 3 years of VA care between 2002-2011. Chronic disease and comorbidities associated with deployment including TBI were identified using diagnosis codes. A latent class analysis (LCA) of longitudinal comorbidity data was used to identify trajectories of comorbidity...
2016: Brain Injury: [BI]
https://www.readbyqxmd.com/read/27828698/at-a-loss-for-words
#20
David A Weidman, Anna D Burke, Garret H Riggs, Helle Brand, Jacquelynn N Copeland, William J Burke
No abstract text is available yet for this article.
August 18, 2016: Primary Care Companion to CNS Disorders
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