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https://www.readbyqxmd.com/read/28088195/automatic-liver-segmentation-based-on-appearance-and-context-information
#1
Yongchang Zheng, Danni Ai, Jinrong Mu, Weijian Cong, Xuan Wang, Haitao Zhao, Jian Yang
BACKGROUND: Automated image segmentation has benefits for reducing clinicians' workload, quicker diagnosis, and a standardization of the diagnosis. METHODS: This study proposes an automatic liver segmentation approach based on appearance and context information. The relationship between neighboring pixels in blocks is utilized to estimate appearance information, which is used for training the first classifier and obtaining the probability distribution map. The map is used for extracting context information, along with appearance features, to train the next classifier...
January 14, 2017: Biomedical Engineering Online
https://www.readbyqxmd.com/read/28081511/spatiotemporal-distributions-of-butyltin-compounds-in-various-intertidal-organisms-along-the-samcheok-and-tongyeong-coasts-of-korea
#2
Taewoo Kim, Seungyeon Jeon, Seongjin Hong, Sung Joon Song, Bong-Oh Kwon, Jongseong Ryu, Jong Seong Khim
Thirteen years ago, the Korean Government introduced a regulation prohibiting the use of tributyltin (TBT), which was a component of antifouling paints. A subsequent decline in the concentration of butyltins (BTs) was recorded in seawater and the sediment, however, the current concentration of BTs in biota has not been well documented. The spatiotemporal distribution and concentration of BTs was recorded in biota from 2013 to 2015 along the coasts of Samcheok and Tongyeong using GS/MSD analysis. Crustaceans contained the greatest concentrations of BTs, followed by gastropods, fishes, and bivalves...
January 2, 2017: Chemosphere
https://www.readbyqxmd.com/read/28080209/dissipation-half-lives-and-mass-spectrometric-identification-of-chlorpyrifos-and-its-two-metabolites-on-field-grown-collard-and-kale
#3
George F Antonious, Eric T Turley, Mutari Abubakari, John C Snyder
The persistence and fate of chlorpyrifos and its two metabolites, chlorpyrifos-oxon and the 3, 5, 6-trichloro-2-pyridinol (TCP) break-down product were investigated on kale and collard leaves under field conditions. A simultaneous extraction and quantification procedure was developed for chrorpyrifos and its two main metabolites. Residues of chlorpyrifos, chlorpyrifos oxon, and TCP were determined using a gas chromatograph (GC) equipped with an electron capture detector (GC/ECD). Chlorpyrifos metabolites were detectable up to 23 days following application...
January 12, 2017: Journal of Environmental Science and Health. Part. B, Pesticides, Food Contaminants, and Agricultural Wastes
https://www.readbyqxmd.com/read/28076809/a-model-for-the-transient-subdiffusive-behavior-of-particles-in-mucus
#4
Matthias Ernst, Thomas John, Marco Guenther, Christian Wagner, Ulrich F Schaefer, Claus-Michael Lehr
In this study we have applied a model to explain the reported subdiffusion of particles in mucus, based on the measured mean squared displacements (MSD). The model considers Brownian diffusion of particles in a confined geometry, made from permeable membranes. The applied model predicts a normal diffusive behavior at very short and long time lags, as observed in several experiments. In between these timescales, we find that the "subdiffusive" regime is only a transient effect, MSD∝τ(α),α<1. The only parameters in the model are the diffusion-coefficients at the limits of very short and long times, and the distance between the permeable membranes L...
January 10, 2017: Biophysical Journal
https://www.readbyqxmd.com/read/28068961/contradictory-individualized-self-blaming-a-cross-sectional-study-of-associations-between-expectations-to-managers-coworkers-one-self-and-risk-factors-for-musculoskeletal-disorders-among-construction-workers
#5
Jeppe Zielinski Nguyen Ajslev, Roger Persson, Lars Louis Andersen
BACKGROUND: Within work sociology, several studies have addressed construction workers' practices of masculinity, class, economy, safety risks and production. However, few studies have investigated room for agency in relation to bodily pain or musculoskeletal disorders and even fewer have made a quantitative approach. Accordingly, by means of a questionnaire, we examined the association between construction workers' room for agency and physical exertion, bodily and mental fatigue, and lower back pain...
January 10, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/28068240/does-unintentional-splenic-radiation-predict-outcomes-after-pancreatic-cancer-radiation-therapy
#6
Awalpreet S Chadha, Guan Liu, Hsiang-Chun Chen, Prajnan Das, Bruce D Minsky, Usama Mahmood, Marc E Delclos, Yelin Suh, Gabriel O Sawakuchi, Sam Beddar, Matthew H Katz, Jason B Fleming, Milind M Javle, Gauri R Varadhachary, Robert A Wolff, Christopher H Crane, Xuemei Wang, Howard Thames, Sunil Krishnan
PURPOSE: To determine whether severity of lymphopenia is dependent on radiation dose and fractional volume of spleen irradiated unintentionally during definitive chemoradiation (CRT) in patients with locally advanced pancreatic cancer (LAPC). METHODS: 177 patients with LAPC received induction chemotherapy (mainly gemcitabine-based regimens) followed by CRT (median 50.4 Gy with concurrent capecitabine) from January 2006 to December 2012. Absolute lymphocyte count (ALC) was recorded at baseline, before CRT, and 2 to 10 weeks after CRT...
February 1, 2017: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/28061870/referring-to-multimodal-rehabilitation-for-patients-with-musculoskeletal-disorders-a-register-study-in-primary-health-care
#7
Charlotte Post Sennehed, Sara Holmberg, Kjerstin Stigmar, Malin Forsbrand, Ingemar F Petersson, Anja Nyberg, Birgitta Grahn
BACKGROUND: In 2008, the Swedish government introduced a National Rehabilitation Program, in which the government financially reimburses the county councils for evidence-based multimodal rehabilitation (MMR) interventions. The target group is patients of working age with musculoskeletal disorders (MSD), expected to return to work or remain at work after rehabilitation. Much attention in the evaluations has been on patient outcomes and on processes. We lack knowledge about how factors related to health care providers and community can have an impact on how patients have access to MMR...
January 7, 2017: BMC Health Services Research
https://www.readbyqxmd.com/read/28047965/tu-h-campus-jep2-05-can-automatic-delineation-of-cardiac-substructures-on-noncontrast-ct-be-used-for-cardiac-toxicity-analysis
#8
Y Luo, Z Liao, W Jiang, D Gomez, R Williamson, L Court, J Yang
PURPOSE: To evaluate the feasibility of using an automatic segmentation tool to delineate cardiac substructures from computed tomography (CT) images for cardiac toxicity analysis for non-small cell lung cancer (NSCLC) patients after radiotherapy. METHODS: A multi-atlas segmentation tool developed in-house was used to delineate eleven cardiac substructures including the whole heart, four heart chambers, and six greater vessels automatically from the averaged 4DCT planning images for 49 NSCLC patients...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047741/th-cd-206-04-learning-relevance-criterion-for-multi-atlas-based-image-segmentation
#9
T Zhao, D Ruan
PURPOSE: It is important to effectively identify the subset of relevant training atlases in learning based segmentation. Since segmentation based geometry relevance between atlases and the target is inaccessible due to the unknown target segmentation, image feature based relevance criteria have to be used instead. This study aims to learn an image based criterion that best reflects the underlying geometry agreement. METHODS: We learn the image-based relevance criterion in the form of a Mahalanobis distance on linearly transformed image feature, which is specialized to image intensity in this work, and optimize such linear transformation...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28046336/su-c-202-02-a-comprehensive-evaluation-of-adaptive-daily-planning-for-cervical-cancer-hdr-brachytherapy
#10
R Meerschaert, A Nalichowski, J Burmeister, A Paul, A Miller, L Zhuang
PURPOSE: To evaluate adaptive daily planning for cervical cancer patients who underwent high-dose-rate intra-cavitary brachytherapy (HDR-ICBT). METHODS: This study included 22 cervical cancer patients who underwent 5 fractions of HDR ICBT. Regions of interest (ROIs) including high-risk clinical tumor volume (HR-CTV) and organs-at-risk (OARs) were manually contoured on daily CT images. All patients were treated with adaptive daily plans, which involved ROI delineation and dose optimization at each treatment fraction...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28046285/su-g-tep1-09-modality-specific-dose-gradient-modeling-for-prostate-imrt-using-spherical-distance-maps-of-ptv-and-isodose-contours
#11
M M Folkerts, X Gu, W Lu, R J Radke, S B Jiang
PURPOSE: Overlapping volume histogram (OVH) and distance-to-target histogram (DTH) calculations rely on the assumption that dose gradients are symmetric with respect to primary target volume (PTV) expansion and minimum distance to PTV surface, respectively. It is desirable to lift this assumption and instead account for achievable modality-specific dose gradients (MSDG) for a given PTV shape. METHODS: From a library of 96 prostate 7-beam IMRT plans, we computed spherical distance maps (SDMs) for PTVs and 3 iso-dose contours...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28042958/standardized-index-of-shape-dce-mri-and-standardized-uptake-value-pet-ct-two-quantitative-approaches-to-discriminate-chemo-radiotherapy-locally-advanced-rectal-cancer-responders-under-a-functional-profile
#12
Antonella Petrillo, Roberta Fusco, Mario Petrillo, Vincenza Granata, Paolo Delrio, Francesco Bianco, Biagio Pecori, Gerardo Botti, Fabiana Tatangelo, Corradina Caracò, Luigi Aloj, Antonio Avallone, Secondo Lastoria
PURPOSE: To investigate dynamic contrast enhanced-MRI (DCE-MRI) in the preoperative chemo-radiotherapy (CRT) assessment for locally advanced rectal cancer (LARC) compared to18F-fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT). METHODS: 75 consecutive patients with LARC were enrolled in a prospective study. DCE-MRI analysis was performed measuring SIS: linear combination of percentage change (Δ) of maximum signal difference (MSD) and wash-out slope (WOS)...
December 22, 2016: Oncotarget
https://www.readbyqxmd.com/read/28032439/a-narrative-review-of-musculoskeletal-problems-of-the-lower-extremity-and-back-associated-with-the-interface-between-occupational-tasks-feet-footwear-and-flooring
#13
REVIEW
Jennifer Anderson, Anita E Williams, Christopher J Nester
At least 50% of workers are exposed to the risk of musculoskeletal disorders (MSD) due to spending prolonged hours standing at work. There is a lack of information regarding issues with the feet, solutions to the problem, and links between MSD, feet, footwear and flooring. The present article provides a narrative review of the research in this area, based on 31 papers. Workers who stand for large proportions of the working day had a level of MSD considerably greater than a normal population. Muscle co-activation, blood pooling, muscle fatigue and individual characteristics are all associated with MSD...
December 29, 2016: Musculoskeletal Care
https://www.readbyqxmd.com/read/28029043/critical-conditions-for-liquid-chromatography-of-statistical-copolymers-functionality-type-and-composition-distribution-characterization-by-up-lccc-esi-ms
#14
Ruben Epping, Ulrich Panne, Jana Falkenhagen
Statistical ethylene oxide (EO) and propylene oxide (PO) copolymers of different monomer compositions and different average molar masses additionally containing to kinds of end groups (FTD) were investigated by Ultra High Pressure Liquid Chromatography under Critical Conditions (UP-LCCC) combined with Electrospray Ionization Time-of Flight Mass Spec-trometry (ESI-TOF-MS). Theoretical predictions of the existence of a Critical Adsorption Point (CPA) for statistical copoly-mers with a given chemical and sequence distribution1, could be studied and confirmed...
December 28, 2016: Analytical Chemistry
https://www.readbyqxmd.com/read/28024500/-hematopoietic-reconstitution-and-prognosis-of-hla-matched-and-haploidentical-hematopoietic-stem-cell-transplantation-using-modified-fc-atg-conditioning-for-treatment-of-severe-aplastic-anemia
#15
Li Wang, Ya-Mei Wu, Yong-Bin Cao, Xiao-Hong Li, Li-Xin Xu, Hai-Tao Wang, Ya-Hui Gao, Xiao-Xiong Wu
OBJECTIVE: To analyse the feasibility and compare differences between hematopoietic reconstitution and prognosis of patients with severe aplastic anemia(SAA) after matched sibling donor (MSD) or haploidentical family donor (HFD) hematopoietic stem cell transplantation (HSCT) using the modified FC/ATG conditioning. METHODS: The clinical data of 56 patients with SAA who received HSCT in First Affiliated Hospital of Chinese PLA General Hospital from January 2011 to June 2016 were analyzed retrospectively...
December 2016: Zhongguo Shi Yan Xue Ye Xue za Zhi
https://www.readbyqxmd.com/read/28024464/a-network-based-systems-biology-platform-for-predicting-disease-metabolite-links
#16
Henri Wathieu, Naiem T Issa, Manisha Mohandoss, Stephen W Byers, Sivanesan Dakshanamurthy
Metabolites constitute phenotypic end products of gene expression, and are key players in biological networks. For this reason, the field of metabolomics has been useful in predicting, explaining, and affecting the mechanisms of disease phenotypes. MSD-MAP (Multi Scale Disease-Metabolite Association Platform) is a powerful computational tool for hypothesizing new links between diseases and metabolites, and characterizing the functional basis of those links in a systems biology context. Upon integrating both predicted and known metabolite-protein associations, MSD-MAP takes a two-pronged approach to associating metabolites to a disease, relying on network-based characterization of disease perturbation at multiple levels of biological activity as well as statistical matching of metabolite- and disease-associated biological profiles...
December 14, 2016: Combinatorial Chemistry & High Throughput Screening
https://www.readbyqxmd.com/read/28018645/a-random-walk-description-of-individual-animal-movement-accounting-for-periods-of-rest
#17
Paulo F C Tilles, Sergei V Petrovskii, Paulo L Natti
Animals do not move all the time but alternate the period of actual movement (foraging) with periods of rest (e.g. eating or sleeping). Although the existence of rest times is widely acknowledged in the literature and has even become a focus of increased attention recently, the theoretical approaches to describe animal movement by calculating the dispersal kernel and/or the mean squared displacement (MSD) rarely take rests into account. In this study, we aim to bridge this gap. We consider a composite stochastic process where the periods of active dispersal or 'bouts' (described by a certain baseline probability density function (pdf) of animal dispersal) alternate with periods of immobility...
November 2016: Royal Society Open Science
https://www.readbyqxmd.com/read/28007789/reproductive-hormones-of-icsi-conceived-young-adult-men-the-first-results
#18
Florence Belva, Mathieu Roelants, Jean De Schepper, André Van Steirteghem, Herman Tournaye, Maryse Bonduelle
STUDY QUESTION: Are reproductive hormone levels (FSH, LH, inhibin B and testosterone) in male offspring conceived by ICSI because of male infertility comparable with those from peers born after spontaneous conception? SUMMARY ANSWER: In this cohort of 54 young men conceived by ICSI because of male-factor infertility, mean and median reproductive hormone levels were found to be comparable with results from spontaneously conceived peers, but ICSI-conceived men were more likely to have low inhibin B (<10th percentile) and high FSH (>90th percentile) levels...
December 21, 2016: Human Reproduction
https://www.readbyqxmd.com/read/28007052/rotavirus-is-frequent-among-adults-hospitalised-for-acute-gastroenteritis
#19
Karen Rokkedal Lausch, Lena Westh, Lena Hagelskjær Kristensen, Jens Lindberg, Britta Tarp, Carsten Schade Larsen
INTRODUCTION: Rotavirus infection is the most common aetiology of acute gastroenteritis (AGE) among young children. In adults, diagnostics focus mainly on bacterial causes, though recent studies suggest that rotavirus is a frequent agent. The aim of this study was to examine the proportion of rotavirus in adults hospitalised with AGE and to identify possible predictors. METHODS: During a 24-month period from 1 May 2010 adults (> 15 years) with AGE admitted to one of four hospitals in the Central Denmark Region were examined for rotavirus with VIKIA Rota-Adeno rapid test in addition to routine culture for bacterial pathogens...
January 2017: Danish Medical Journal
https://www.readbyqxmd.com/read/28003774/effectiveness-of-the-multidimensional-ergonomic-intervention-model-to-reduce-musculoskeletal-discomfort-among-street-sweepers-in-chiang-rai-province-thailand
#20
Kanjanar Pintakham, Wattasit Siriwong
The aim of this study was to evaluate the effectiveness of multidimensional ergonomic intervention (MEI) model to reduce musculoskeletal discomfort (MSD) among street sweepers. A quasi-experimental study was conducted in Chiang Rai Province. The MEI model was designed on the basis of four core components: cognitive behavior therapy, ergonomic education training, stretching exercise, and the foam sleeve broom handle grip. Seventy-five street sweepers volunteered for the screening process on MSD of having level score ≥4 by physiotherapist...
2016: Risk Management and Healthcare Policy
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