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https://www.readbyqxmd.com/read/28418753/intraosseous-pressure-monitoring-in-healthy-volunteers
#1
Joshua G Salzman, Nicholas M Loken, Sandi S Wewerka, Aaron M Burnett, Abigail E Zagar, Kent R Griffith, Peter L Bliss, Bjorn K Peterson, Christopher J Ward, Ralph J Frascone
STUDY OBJECTIVE: Invasively monitoring blood pressure through the IO device has not been thoroughly demonstrated. This study attempted to establish baseline values of IO pressure in a healthy human population. METHODS: This was a prospective, healthy volunteer, observational study. Participants had two IO devices placed (humerus and tibia), and participant IO pressures, vital signs, and pain scores were monitored for up to 60 minutes. Participants were contacted at 24-hours and 7 days post-testing to assess for adverse events...
April 18, 2017: Prehospital Emergency Care
https://www.readbyqxmd.com/read/28321651/effects-of-strontium-ranelate-treatment-on-osteoblasts-cultivated-onto-scaffolds-of-trabeculae-bovine-bone
#2
Gerluza Aparecida Borges Silva, Bruno Machado Bertassoli, Cristiane Aparecida Sousa, Juliano Douglas Albergaria, Rayan Silva de Paula, Erika Cristina Jorge
Blocks of Bovine bone have shown promising results as implantable scaffolds to promote bone regeneration. Strontium ranelate (SrR) is both an antiresorptive and an anabolic drug that has been indicated for oral administration to treat osteoporosis. Few studies, however, have investigated the local effects of SrR and its use in association with biomaterials thus far. In this work, we investigated SrR effects in cultures of primary osteoblasts (PO, from Wistar rats calvaria) and immortalized osteoblasts (IO, from MC3T3-E1 cell line) cultivated as a monolayer or in association with scaffolds of bovine bone in mineralized (MBB) and demineralized (DBB) forms...
March 20, 2017: Journal of Bone and Mineral Metabolism
https://www.readbyqxmd.com/read/28292276/effect-of-modified-graded-recession-and-anteriorization-on-unilateral-superior-oblique-palsy-a-retrospective-study
#3
Dong Cheol Lee, Se Youp Lee
BACKGROUND: Several inferior oblique (IO) weakening methods exist for correction of superior oblique palsy (SOP). A previously reported method involved recession and anteriorization according to IO overaction (IOOA) grade, which might be subjective and cause upgaze limitation and opposite vertical strabismus. Therefore, this study attempted to examine the efficacy of modified graded recession and anteriorization of the IO muscle in correction of unilateral SOP without resulting in upgaze limitation or opposite vertical strabismus...
March 14, 2017: BMC Ophthalmology
https://www.readbyqxmd.com/read/28249215/electrochemical-regeneration-of-a-reduced-graphene-oxide-magnetite-composite-adsorbent-loaded-with-methylene-blue
#4
Farbod Sharif, Luke R Gagnon, Suresh Mulmi, Edward P L Roberts
In this work, two different reduced graphene oxide/iron oxide (rGO-IO) nanocomposites with different iron oxide loadings were fabricated using a one-step solvothermal method. The structure, properties and applications of the synthesized nanocomposites were evaluated with Raman spectroscopy, attenuated total reflectance Fourier transform infrared spectroscopy, thermogravimetric analysis, X-ray diffraction, electron microscopy, and energy-dispersive X-ray spectroscopy. The iron oxide is in the form of magnetite (Fe3O4), so that the resultant adsorbent can readily be separated from the treated water using a magnetic field...
May 1, 2017: Water Research
https://www.readbyqxmd.com/read/28078397/optimized-synthesis-of-novel-prenyl-ferulate-performed-by-feruloyl-esterases-from-myceliophthora-thermophila-in-microemulsions
#5
Io Antonopoulou, Laura Leonov, Peter Jütten, Gabriella Cerullo, Vincenza Faraco, Adamantia Papadopoulou, Dimitris Kletsas, Marianna Ralli, Ulrika Rova, Paul Christakopoulos
Five feruloyl esterases (FAEs; EC 3.1.1.73), FaeA1, FaeA2, FaeB1, and FaeB2 from Myceliophthora thermophila C1 and MtFae1a from M. thermophila ATCC 42464, were tested for their ability to catalyze the transesterification of vinyl ferulate (VFA) with prenol in detergentless microemulsions. Reaction conditions were optimized investigating parameters such as the medium composition, the substrate concentration, the enzyme load, the pH, the temperature, and agitation. FaeB2 offered the highest transesterification yield (71...
April 2017: Applied Microbiology and Biotechnology
https://www.readbyqxmd.com/read/28012017/surgical-exploration-in-persistent-inferior-oblique-overactions
#6
Feray Koc
PURPOSE: To report the causes of persistent inferior oblique (IO) overactions after disinsertion procedure. METHODS: Surgical findings of nine eyes of eight patients who needed secondary surgery to the IO muscles because of persistent overaction after IO disinsertion were evaluated retrospectively. Inferior obliques were found partially retracted into their sheath, and some parts of the proximal muscle stumps were found to have established attachments through scar tissues to the sclera in five eyes...
December 24, 2016: International Ophthalmology
https://www.readbyqxmd.com/read/28003983/essential-infantile-esotropia-with-inferior-oblique-hyperfunction-long-term-follow-up-of-6-muscles-approach
#7
Adriano Magli, Roberta Carelli, Elisabetta Chiariello Vecchio, Francesca Esposito, Luca Rombetto, Paolo Esposito Veneruso
AIM: To evaluate long term follow-up (10y) of 6 muscle surgical approach in essential infantile esotropia (EIE). METHODS: A 6 muscle approach to EIE was retrospectively evaluated in patients with inferior oblique (IO) hyperfunction and lateral rectus (LR) pseudoparalysis, who underwent surgery at different ages. Different clinical characters were analyzed pre- and postoperatively, in patients who underwent a 6 muscles approach ≤4 years of age. All patients underwent a multiple muscles approach: bilateral medial recti (MR) recession (4-5 mm), bilateral LR resection (lower than 7 mm) and bilateral IO recession and anteroposition...
2016: International Journal of Ophthalmology
https://www.readbyqxmd.com/read/27853019/can-a-dermoid-cyst-lead-to-an-abnormal-origin-of-an-extraocular-muscle
#8
Tayyab Afghani, Hassan Mansoor
A 5-year-old boy presented with a large 5 cm × 5 cm cyst covering the left eye completely since birth. The cyst was excised in toto and was sent for histopathological examination. During the surgery, the inferior oblique (IO) muscle was seen originating from medial orbital wall, 10-12 mm behind the medial orbital margin, just posterior to the lacrimal bone and moving laterally, downward, and posteriorly from its origin making a more acute angle - around 20° to its site of origin. The insertion of the IO to sclera was at its normal site...
September 2016: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/27809922/analysis-of-thromboelastography-pt-aptt-and-fibrinogen-in-intraosseous-and-venous-samples-an-experimental-study
#9
Gunnar Strandberg, Miklós Lipcsey, Mats Eriksson, Norbert Lubenow, Anders Larsson
BACKGROUND: Laboratory analysis of coagulation is often important in emergencies. If vascular access is challenging, intraosseous catheterization may be necessary for treatment. We studied the analysis of coagulation parameters in intraosseous aspirate during stable conditions and after major haemorrhage in a porcine model. METHODS: Ten anesthetized pigs received central venous and intraosseous catheters and samples were taken for analysis of thromboelastography (TEG), prothrombin time (PT), activated partial thromboplastin time (APTT) and fibrinogen concentration...
November 3, 2016: Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine
https://www.readbyqxmd.com/read/27805541/inulin-oligofructose-attenuates-metabolic-syndrome-in-high-carbohydrate-high-fat-diet-fed-rats
#10
Senthil A Kumar, Leigh C Ward, Lindsay Brown
Prebiotics alter bacterial content in the colon, and therefore could be useful for obesity management. We investigated the changes following addition of inulin oligofructose (IO) in the food of rats fed either a corn starch (C) diet or a high-carbohydrate, high-fat (H) diet as a model of diet-induced metabolic syndrome. IO did not affect food intake, but reduced body weight gain by 5·3 and 12·3 % in corn starch+inulin oligofructose (CIO) and high-carbohydrate, high-fat with inulin oligofructose (HIO) rats, respectively...
November 2016: British Journal of Nutrition
https://www.readbyqxmd.com/read/27390660/evaluation-of-actual-and-estimated-hydraulic-conductivity-of-sands-with-different-gradation-and-shape
#11
Ali Firat Cabalar, Nurullah Akbulut
Hydraulic conductivities of sands with different gradation and grain shape were estimated experimentally at a relative density (Dr) of about 40 % and a 22 ± 2 °C of constant temperature. Narli Sand (NS) with 0.67 of sphericity (S) and 0.72 of roundness (R), and Crushed Stone Sand (CSS) with 0.55 of S and 0.15 of R values were artificially graded into sixteen different grain-size fractions (4.75-2, 2-1.18, 1.18-0.6, 0.6-0.425, 0.425-0.3, 0.3-0.075, 4.75-0.075, 2-0.075, 1.18-0.075, 0.6-0.075, 0.425-0.075, 4...
2016: SpringerPlus
https://www.readbyqxmd.com/read/27344097/intraosseous-access-in-the-obese-patient-assessing-the-need-for-extended-needle-length
#12
Thompson Kehrl, Brent A Becker, Dell E Simmons, Erin K Broderick, Robert A Jones
BACKGROUND: Intraosseous (IO) access can be complicated by obesity. Successful placement of a 25 mm IO needle is unlikely when soft tissue depth exceeds 20 mm. OBJECTIVES: The authors examined the relationship between body mass index (BMI), the ability to palpate the tibial tuberosity (TT), and soft tissue depth at recommended IO insertion sites. METHODS: Obese emergency department patients were assessed for a palpable TT and received ultrasound measurement of the soft tissue depth at recommended IO insertion sites...
September 2016: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/27129093/computed-tomography-generated-anthropometric-measurements-of-orbital-relationships-in-normal-infants-and-children
#13
Garrett M Pool, Ryne A Didier, Dianna Bardo, Nathan R Selden, Anna A Kuang
OBJECTIVE The aim of this study was to develop soft-tissue and bony anthropometric orbital measurements in a normal pediatric population based upon CT scans. METHODS This was a retrospective stratified study of children with ages ranging from birth to 36 months. Head CT images for 204 children were available and obtained with 0.625-1-mm slice widths. Soft-tissue and bone windows were reviewed. Images were oriented in the Frankfort horizontal plane, and the intercanthal (IC), bony interorbital (IO), and bony lateral orbital (LO) distances were measured...
August 2016: Journal of Neurosurgery. Pediatrics
https://www.readbyqxmd.com/read/27119066/impact-of-preoperative-ultrasonography-findings-on-the-patency-rate-of-vascular-access-in-japanese-hemodialysis-patients
#14
Junichiro Nakata, Hiroaki Io, Tomonari Watanabe, Yu Sasaki, Yuko Makita, Tatsuya Aoki, Hiroyuki Yanagawa, Reo Kanda, Yasuhiko Tomino
BACKGROUND: Although ultrasonography before a vascular access (VA) operation has become popular in recent years, benchmarks for the diameter or blood flow of arteries or veins are not defined in Japan. The objective of the present study is to analyze the relationship between preoperative US findings and the patency rate of VA in Japanese hemodialysis patients. METHODS: 139 patients with end stage kidney disease were enrolled in this study. They had been given primary radiocephalic arteriovenous fistula (AVF) from February 2009 to December 2010 at the Juntendo University Hospital and were followed up over 2 years...
2016: SpringerPlus
https://www.readbyqxmd.com/read/27012496/is-mri-helpful-in-assessing-the-distance-of-the-tumour-from-the-internal-os-in-patients-with-cervical-cancer-below-figo-stage-ib2
#15
P R Bhosale, R B Iyer, P Ramalingam, K M Schmeler, W Wei, R L Bassett, P T Ramirez, M Frumovitz
AIM: To determine the ability of magnetic resonance imaging (MRI) in detecting tumour-free margins from the internal os (IO). MATERIALS AND METHODS: A database search yielded 79 women with early-stage cervical cancer who underwent radical hysterectomy and preoperative MRI. The sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and accuracy of MRI in assessment of ≤5 and >5 mm IO involvement were calculated with histopathological surgical specimen findings considered to be the reference standard...
June 2016: Clinical Radiology
https://www.readbyqxmd.com/read/26895287/collimator-optimization-in-myocardial-perfusion-spect-using-the-ideal-observer-and-realistic-background-variability-for-lesion-detection-and-joint-detection-and-localization-tasks
#16
Michael Ghaly, Yong Du, Jonathan M Links, Eric C Frey
In SPECT imaging, collimators are a major factor limiting image quality and largely determine the noise and resolution of SPECT images. In this paper, we seek the collimator with the optimal tradeoff between image noise and resolution with respect to performance on two tasks related to myocardial perfusion SPECT: perfusion defect detection and joint detection and localization. We used the Ideal Observer (IO) operating on realistic background-known-statistically (BKS) and signal-known-exactly (SKE) data. The areas under the receiver operating characteristic (ROC) and localization ROC (LROC) curves (AUCd, AUCd+l), respectively, were used as the figures of merit for both tasks...
March 7, 2016: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/26894376/collimator-optimization-and-collimator-detector-response-compensation-in-myocardial-perfusion-spect-using-the-ideal-observer-with-and-without-model-mismatch-and-an-anthropomorphic-model-observer
#17
Michael Ghaly, Jonathan M Links, Eric C Frey
The collimator is the primary factor that determines the spatial resolution and noise tradeoff in myocardial perfusion SPECT images. In this paper, the goal was to find the collimator that optimizes the image quality in terms of a perfusion defect detection task. Since the optimal collimator could depend on the level of approximation of the collimator-detector response (CDR) compensation modeled in reconstruction, we performed this optimization for the cases of modeling the full CDR (including geometric, septal penetration and septal scatter responses), the geometric CDR, or no model of the CDR...
March 7, 2016: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/26663304/intraosseous-hydroxocobalamin-versus-intravenous-hydroxocobalamin-compared-to-intraosseous-whole-blood-or-no-treatment-for-hemorrhagic-shock-in-a-swine-model
#18
Vikhyat S Bebarta, Normalynn Garrett, Susan Boudreau, Maria Castaneda
OBJECTIVE: To determine if intraosseous (IO) hydroxocobalamin can improve systolic blood pressure (SBP) in a swine model after severe hemorrhagic shock. METHODS: Thirty six swine (45-55 kg) were anesthetized, intubated, and instrumented with continuous femoral and pulmonary artery pressure monitoring and then hemorrhaged such that 30 percent of their blood volume was extracted over 20 minutes. Five minutes later, animals were randomly assigned to receive 500 mL IO whole blood, 150 mg/kg IO or intravenous (IV) hydroxocobalamin in 180 mL of saline, or no treatment and then monitored for 60 minutes...
2015: American Journal of Disaster Medicine
https://www.readbyqxmd.com/read/26315115/preliminary-results-of-a-prospective-study-of-inter-and-intra-user-variability-of-the-royal-veterinary-college-corneal-clarity-score-rvc-ccs-for-use-in-veterinary-practice
#19
Rick F Sanchez, Charlotte Dawson, Màrian Matas Riera, Natàlia Escanilla
OBJECTIVE: To introduce a new corneal clarity score for use in small animals and describe its inter- and intra-user variability. ANIMALS STUDIED: Twelve dogs and two cats with corneal abnormalities and five dogs with healthy corneas. MATERIALS AND METHODS: Four examiners scored every patient twice and never consecutively, focusing on the central cornea. The peripheral cornea was scored separately. The following scoring system was used to describe corneal clarity: G0: no fundus reflection is visible on retroillumination (RI) using a head-mounted indirect ophthalmoscope...
July 2016: Veterinary Ophthalmology
https://www.readbyqxmd.com/read/26300243/intraosseous-access-in-neonates-and-infants-risk-of-severe-complications-a-case-report
#20
P K Suominen, E Nurmi, K Lauerma
Gaining vascular access in a neonate during cardiopulmonary resuscitation is crucial and challenging. Intraosseous (IO) access can offer a fast and reliable method for achieving emergency access for fluids and drugs when venous access fails in a critically ill child. IO access can however result in rare, but serious adverse events including compartment syndrome and amputation. We describe a case resulting in leg amputation due to IO infusion in a neonate after resuscitation and therapeutic hypothermia. We compared 10 tibia X-rays in three age groups...
November 2015: Acta Anaesthesiologica Scandinavica
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