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Semin Ryu, Dongbum Pyo, Soo-Chul Lim, Dong-Soo Kwon
Recently, various methods using, simultaneously, two types of tactile feedback have been proposed to emulate a real object. However, the possible masking effect when providing two types of tactile feedback has been scarcely reported. In this study, we investigated the masking effect caused by mechanical vibration on the perception of electrovibration. The absolute and difference thresholds of the electrovibration were measured according to the presence/absence, frequency, and intensity of the mechanical vibration...
March 14, 2018: Scientific Reports
David M Tehrani, Daniel Rodgers, Sirtaz Adatya, Nitasha Sarswat, Jayant Raikhelkar, Gene H Kim, Gabriel Sayer, Nir Uriel
We aim to evaluate the echocardiographic/hemodynamic effects of left ventricular assist devices in African American (AA) versus non-AA patients undergoing ramp speed optimization and its subsequent effect on readmissions. In 65 patients (26 AA), no differences in baseline echocardiographic/hemodynamic parameters were noted. During ramp testing, there was a significantly greater increase in cardiac output (slope: 0.29 ± 0.24 vs. 0.15 ± 0.12, p < 0.01) with more rapid decrease in left ventricular end-diastolic diameter (slope: -0...
March 13, 2018: ASAIO Journal: a Peer-reviewed Journal of the American Society for Artificial Internal Organs
Stéphanie Gamache, François Routhier, Ernesto Morales, Marie-Hélène Vandersmissen, Normand Boucher
BACKGROUND: Due to the ageing population and higher prevalence of individuals living with physical disabilities, there is a critical need for inclusive practices when designing accessible pedestrian infrastructures for ensuring social participation and equal opportunities. PURPOSE: Summarize the physical characteristics of current pedestrian infrastructure design for individuals with physical disabilities (IPD - motor, visual and hearing) found in the scientific literature and assess its quality...
March 14, 2018: Disability and Rehabilitation. Assistive Technology
Juan M Murias, Silvia Pogliaghi, Donald H Paterson
The accuracy of an exhaustive ramp incremental (RI) test to determine maximal oxygen uptake ([Formula: see text]O2max ) was recently questioned and the utilization of a verification phase proposed as a gold standard. This study compared the oxygen uptake ([Formula: see text]O2 ) during a RI test to that obtained during a verification phase aimed to confirm attainment of [Formula: see text]O2max . Sixty-one healthy males [31 older (O) 65 ± 5 yrs; 30 younger (Y) 25 ± 4 yrs] performed a RI test (15-20 W/min for O and 25 W/min for Y)...
2018: Frontiers in Physiology
Stefan O Schrade, Katrin Dätwyler, Marius Stücheli, Kathrin Studer, Daniel-Alexander Türk, Mirko Meboldt, Roger Gassert, Olivier Lambercy
BACKGROUND: Powered exoskeletons are a promising approach to restore the ability to walk after spinal cord injury (SCI). However, current exoskeletons remain limited in their walking speed and ability to support tasks of daily living, such as stair climbing or overcoming ramps. Moreover, training progress for such advanced mobility tasks is rarely reported in literature. The work presented here aims to demonstrate the basic functionality of the VariLeg exoskeleton and its ability to enable people with motor complete SCI to perform mobility tasks of daily life...
March 13, 2018: Journal of Neuroengineering and Rehabilitation
X W Xu, R C Zhang, Y P Mou, Z Y Qian, C J Huang, Q C Zhu, W W Jin, Y C Zhou
Objective: To evaluate the safety and feasibility of laparoscopic radical antegrade modular pancreatosplenectomy(Lap-RAMPS) for left-sided pancreatic adenocarcinoma. Methods: Clinical data of total 12 patients underwent Lap-RAMPS for left-sided pancreatic adenocarcinoma at Department of Gastrointestinal and Pancreatic Surgery, Zhejiang Provincial People's Hospital from March 2016 to August 2017 were reviewed retrospectively.There were 7 male patients and 5 female patients, with median age of 60.5 years old(47-68 years old)...
March 1, 2018: Zhonghua Wai Ke za Zhi [Chinese Journal of Surgery]
Craig K Abbey, Frank W Samuelson, Rongping Zeng, John M Boone, Miguel P Eckstein, Kyle Myers
PURPOSE: This study investigates forced-localization of targets in simulated images with statistical properties similar to trans-axial sections of x-ray computed tomography (CT) volumes. A total of 24 imaging conditions are considered, comprising 2 target sizes, 3 levels of background variability, and 4 levels of frequency apodization. The goal of the study is to better understand how human observers perform forced-localization tasks in images with CT-like statistical properties. METHODS: The transfer properties of CT systems are modeled by a shift-invariant transfer function in addition to apodization filters that modulate high spatial frequencies...
March 12, 2018: Medical Physics
K Jeannet Oyen, Michael E Dillon
Critical thermal limits often determine species distributions for diverse ectotherms and have become a useful tool for understanding past and predicting future range shifts in response to changing climates. Despite recently documented population declines and range shifts of bumble bees (genus Bombus ), the few measurements of thermal tolerance available for the group have relied on disparate measurement approaches. We describe a novel stereotypical behavior expressed by bumble bee individuals during entry into chill coma...
March 12, 2018: Journal of Experimental Biology
Macellina Y Ijadunola, Temitope O Ojo, Florence O Akintan, Ayoade O Adeyemo, Ademola S Afolayan, Olakunle G Akanji
PURPOSE: This study assessed awareness and availability of assistive facilities in a Nigerian public university. METHODS: Study was conducted in Obafemi Awolowo University (OAU), Ile Ife Nigeria using a mixed methods approach. Fifty two students with disability (SWD) were interviewed with a semistructured, self-administered questionnaire. A checklist was used to assess assistive facilities on campus while in-depth interviews (IDI) were conducted with university officials, to assess their perspectives about the availability and use of assistive facilities in the university...
March 12, 2018: Disability and Rehabilitation. Assistive Technology
Ryan J Colquhoun, Mitchel A Magrini, Cody T Haun, Tyler W D Muddle, Patrick M Tomko, Micheal J Luera, Cameron S Mackey, Christopher G Vann, Jeffrey S Martin, Kaelin C Young, Jason M DeFreitas, Michael D Roberts, Nathaniel D M Jenkins
Previous investigations have reported a relationship between skeletal muscle phenotype and motor unit (MU) firing parameters during submaximal contractions. The purpose of the current investigation, however, was to examine the relationships between motor unit firing behavior during a maximal voluntary contraction, Myosin Heavy Chain (MHC) isoform content, and various molecular neuromuscular targets of the vastus lateralis (VL) muscle in resistance-trained men. Ten resistance-trained males completed a trapezoidal ramp contraction up to 100% of their maximal voluntary isometric strength (MVIC)...
March 2018: Physiological Reports
Steven M Barlow, Mohsen Hozan, Jaehoon Lee, Jake Greenwood, Rebecca Custead, Brianna Wardyn, Kaytlin Tippin
The relation among several parameters of the ramp-and-hold isometric force contraction (peak force and dF/dtmax during the initial phase of force recruitment, and the proportion of hold-phase at target) was quantified for the right and left thumb-index finger pinch, and lower lip midline compression in 40 neurotypical right-handed young adults (20 female/20 males) using wireless force sensors and data acquisition technology developed in our laboratory. In this visuomotor control task, participants produced ramp-and-hold isometric forces as 'rapidly and accurately' as possible to end-point target levels at 0...
March 6, 2018: Journal of Biomechanics
Shotaro Kawakami, Tetsuhiko Yasuno, Takuro Matsuda, Kanta Fujimi, Ai Ito, Saki Yoshimura, Yoshinari Uehara, Hiroaki Tanaka, Takao Saito, Yasuki Higaki
BACKGROUND: High-intensity exercise reduces renal blood flow (RBF) and may transiently exacerbate renal dysfunction. RBF has previously been measured invasively by administration of an indicator material; however, non-invasive measurement is now possible with technological innovations. This study examined variations in RBF at different exercise intensities using ultrasound echo. METHODS: Eight healthy men with normal renal function (eGFRcys 114 ± 19 mL/min/1...
March 10, 2018: Clinical and Experimental Nephrology
Dalton T Snyder, Lucas J Szalwinski, Robert L Schrader, Valentina Pirro, Ryan Hilger, R Graham Cooks
Methodology for performing precursor and neutral loss scans in an RF scanning linear quadrupole ion trap is described and compared to the unconventional ac frequency scan technique. In the RF scanning variant, precursor ions are mass selectively excited by a fixed frequency resonance excitation signal at low Mathieu q while the RF amplitude is ramped linearly to pass ions through the point of excitation such that the excited ion's m/z varies linearly with time. Ironically, a nonlinear ac frequency scan is still required for ejection of the product ions since their frequencies vary nonlinearly with the linearly varying RF amplitude...
March 9, 2018: Journal of the American Society for Mass Spectrometry
T D London, J A Licholai, I Szczot, M A Ali, K H LeBlanc, W C Fobbs, A V Kravitz
The striatum controls food-related actions and consumption and is linked to feeding disorders including obesity and anorexia nervosa. Two populations of neurons project from the striatum: direct pathway medium spiny neurons (dMSNs) and indirect pathway medium spiny neurons (iMSNs). The selective contribution of dMSNs and iMSNs to food-related actions and consumption remains unknown. Here, we used in vivo electrophysiology and fiber photometry in mice (of both sexes) to record both spiking activity and pathway-specific calcium activity of dorsal striatal neurons during approach to and consumption of food pellets...
March 9, 2018: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
Andrew G Baker, Cho-Ying Chuang, Miles Whitmore, Matthew J Comstock
Acousto-optic (AO) devices have been used extensively in optical tweezers because of their flexibility and speed; however, these devices have trap positioning inaccuracies that limit their usefulness, especially for high-resolution applications. We show that these inaccuracies are due to interference patterns within the AO device sound fields. We have devised a method that removes these inaccuracies by reducing the coherence of the sound fields by directly controlling and randomizing the phase of the radio frequency voltage input signal...
March 10, 2018: Applied Optics
Minu R Pilvankar, Michele A Higgins, Ashlee N Ford Versypt
Diabetic kidney disease (DKD) is the primary cause of kidney failure. Diabetic hyperglycemia primarily damages podocyte cells. Podocytes express a local renin-angiotensin system (RAS) that produces angiotensin II (ANG II). ANG II levels are elevated by hyperglycemia, triggering podocyte injury. Quantitative descriptions of glucose dose dependency of ANG II are scarce in the literature. For better understanding of the mechanism of glycemic injury in DKD, a mathematical model is developed to describe the glucose-stimulated local RAS in podocytes...
March 8, 2018: Bulletin of Mathematical Biology
Lorenz Hruby, Nishant Dogra, Manuele Landini, Tobias Donner, Tilman Esslinger
We experimentally study the stability of a bosonic Mott insulator against the formation of a density wave induced by long-range interactions and characterize the intrinsic dynamics between these two states. The Mott insulator is created in a quantum degenerate gas of 87-Rubidium atoms, trapped in a 3D optical lattice. The gas is located inside and globally coupled to an optical cavity. This causes interactions of global range, mediated by photons dispersively scattered between a transverse lattice and the cavity...
March 8, 2018: Proceedings of the National Academy of Sciences of the United States of America
C E Andriakopoulou, A A Zadpoor, M H Grant, P E Riches
Collagen gels are considered a promising biomaterial for the manufacturing of tissue engineering scaffolds, however, their mechanical properties often need to be improved to enable them to provide enough mechanical support during the course of tissue regeneration process. In this paper, we present a simple self-compression technique for the improvement of the mechanical properties of collagen gels, identified by the fitting of bespoke biphasic finite element models. Radially-confined highly hydrated gels were allowed to self-compress for 18h, expelling fluid, and which were subsequently subjected to unconfined ramp-hold compression...
March 1, 2018: Materials Science & Engineering. C, Materials for Biological Applications
Anteneh Amsalu, Getachew Ferede, Demissie Assegu
BACKGROUND: Despite availability of effective treatment and the implementation of focused antenatal care (ANC), still the prevalence of syphilis persists in Ethiopia. Yet, data is not found in southern Ethiopia. Therefore, this study was conducted to determine the seroprevalence and associated factors of syphilis among pregnant women in Yiregalem Hospital, Southern Ethiopia. METHODS: A cross-sectional study was conducted among pregnant women from October 2015 to August 2016...
March 6, 2018: BMC Infectious Diseases
Maria Cristina Mascolo, Terry Arthur Ring
Recyclable aggregates of mesoporous titania with different anatase-rutile ratios have been prepared by thermal treatments of either amorphous or peptized precursors. These last two have been obtained by hydrolysis of either Ti(OC₂H₅)₄ or of Ti(OC₂H₅)₄ in mixture with 5 mol % Zr(OC₃H₇)₄ at room temperature in the presence of NH₄OH as a catalyzing agent. The anatase-rutile ratio, the recyclable aggregates of the nano-sized particles, the mesoporosity, the surface area and the crystallinity of the resulting crystallized products of titania can be controlled by the synthesis parameters including: concentration of ammonia catalyst, stirring time and concentration of the peptizing HNO₃, drying method of peptized precursors, calcination temperature, and finally the ramp rate up to the titania crystallization temperature...
March 5, 2018: Materials
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