Kaiwen Xu, Mirza S Khan, Thomas Li, Riqiang Gao, Sanja L Antic, Yuankai Huo, Kim L Sandler, Fabien Maldonado, Bennett A Landman
In lung cancer screening, estimation of future lung cancer risk is usually guided by demographics and smoking status. The role of constitutional profiles of human body, a.k.a. body habitus, is increasingly understood to be important, but has not been integrated into risk models. Chest low dose computed tomography (LDCT) is the standard imaging study in lung cancer screening, with the capability to discriminate differences in body composition and organ arrangement in the thorax. We hypothesize that the primary phenotypes identified using lung screening chest LDCT can form a representation of body habitus and add predictive power for lung cancer risk stratification...
February 2023: Proceedings of SPIE