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https://www.readbyqxmd.com/read/28445800/adjunctive-celecoxib-for-schizophrenia-a-meta-analysis-of-randomized-double-blind-placebo-controlled-trials
#1
Wei Zheng, Dong-Bin Cai, Xin-Hu Yang, Gabor S Ungvari, Chee H Ng, Norbert Müller, Yu-Ping Ning, Yu-Tao Xiang
Neuroinflammation has been implicated in the neurobiological pathways of schizophrenia. This meta-analysis evaluated the efficacy and tolerability of adjunctive celecoxib as a noncompetitive anti-inflammation drug in treating schizophrenia. Data were searched, extracted, checked and entered into the RevMan (version 5.3) software by two independent investigators. Standardized/weighted mean differences (SMDs/WMDs), risk ratio (RR) and their 95% confidence intervals (CIs) were calculated, as appropriate. Included were 8 randomized controlled trials (RCTs) with a total of 626 patients with schizophrenia including 316 (50...
April 14, 2017: Journal of Psychiatric Research
https://www.readbyqxmd.com/read/28445437/an-exploratory-study-on-the-influence-of-psychopathological-risk-and-impulsivity-on-bmi-and-perceived-quality-of-life-in-obese-patients
#2
Renata Tambelli, Luca Cerniglia, Silvia Cimino, Giulia Ballarotto, Marinella Paciello, Carla Lubrano, Serena Marchitelli, Lucio Gnessi, Andrea Lenzi
The present study aimed to assess the psychological profiles of adult male and female obese patients, as well as to verify the possible influence of their psychopathological risk and impulsivity on their body mass index (BMI) and perceived quality of life. A total of 64 obese subjects accessing a center for care of their obesity were assessed through anthropometric and psychometric measurements. All anthropometric measures in men were higher than in women, while in turn, women showed higher psychopathological symptoms...
April 26, 2017: Nutrients
https://www.readbyqxmd.com/read/28445399/advances-in-psychiatric-diagnosis-past-present-and-future
#3
EDITORIAL
Carol S North, Alina M Surís
This editorial examines controversies identified by the articles in this special issue, which explore psychopathology in the broad history of the classification of selected psychiatric disorders and syndromes over time through current American criteria. Psychiatric diagnosis has a long history of scientific investigation and application, with periods of rapid change, instability, and heated controversy associated with it. The articles in this issue examine the history of psychiatric nomenclature and explore current and future directions in psychiatric diagnosis through the various versions of accepted diagnostic criteria and accompanying research literature addressing the criteria...
April 26, 2017: Behavioral Sciences
https://www.readbyqxmd.com/read/28444659/new-psychoactive-substances-nps-a-challenge-for-the-addiction-treatment-services
#4
Norbert Scherbaum, F Schifano, Udo Bonnet
Over the last few years, hundreds of new psychoactive substances (NPS) have been identified in Europe. Apart from some herbal compounds, NPS mainly include synthetic cannabinoids and a range of new synthetic stimulants (e. g., cathinones). Synthetic NPS are often developed whilst modifying the basic chemical (e. g., phenethylamine or tryptamine) structure. Although the pharmacology and toxicology of most NPS are hardly known, they are being offered, especially online, as "bath salts," as "incense mixtures," or under other misleading labels...
April 25, 2017: Pharmacopsychiatry
https://www.readbyqxmd.com/read/28444578/experimental-psychosis-research-and-schizophrenia-similarities-and-dissimilarities-in-psychopathology
#5
Leo Hermle, Rainer Kraehenmann
The aim of experimental psychopathology is to delineate overlapping functional disorders of psychoneurobiologically-defined systems where a set of common symptoms may correspond to a variety of nosological entities. According to the vulnerability model of psychosis, experimental research needs to go beyond categories such as "schizophrenia". Prospective studies of the effects of psychoactive substances in normal control subjects offer several methodological advantages over routine clinical reviews of schizophrenic patients, especially in terms of standardization...
April 26, 2017: Current Topics in Behavioral Neurosciences
https://www.readbyqxmd.com/read/28444574/a-randomized-controlled-trial-of-the-effectiveness-of-a-psychoeducational-intervention-on-family-caregivers-of-patients-with-mental-disorders
#6
Viviane Tabeleão, Elaine Tomasi, Luciana de Avila Quevedo
The present study aimed to investigate the effectiveness of a psychoeducational intervention on caregivers of patients assisted by the Center for Psychosocial Health Care (CPHC) focusing on the patient's psychopathology. This was a randomized clinical trial with 130 caregivers with higher mean burden scores assessed using the Zarit Burden Interview Scale (ZBI) (66 caregivers in the intervention group and 64 in the control group). The intervention included six home visits of psychoeducational interventions according to each mental disorder identified in the CPHC records...
April 25, 2017: Community Mental Health Journal
https://www.readbyqxmd.com/read/28444481/peer-victimization-and-suicidal-thoughts-and-behaviors-in-depressed-adolescents
#7
Jeremy G Stewart, Linda Valeri, Erika C Esposito, Randy P Auerbach
Suicide is a leading cause of death among youth worldwide, and depressed adolescents are at a significantly elevated risk to report suicidal ideation, planning, and attempts. Peer victimization is a robust predictor of adolescent suicidal thoughts and behaviors (STBs), but little research has focused on why bullying leads to suicidal thoughts and behaviors. To address this empirical gap, we recruited 340 (246 female) depressed adolescents ages 13-19 (M = 15.59, SD = 1.41) within 48 h of admission for acute psychiatric treatment...
April 25, 2017: Journal of Abnormal Child Psychology
https://www.readbyqxmd.com/read/28444137/effects-of-serotonin-transporter-gene-variation-on-impulsivity-mediated-by-default-mode-network-a-family-study-of-depression
#8
Jiook Cha, Guia Guffanti, Jay Gingrich, Ardesheer Talati, Priya Wickramaratne, Myrna Weissman, Jonathan Posner
Serotonergic neurotransmission, potentially through effects on the brain's default mode network (DMN), may regulate aspects of attention including impulse control. Indeed, genetic variants of the serotonin transporter (5-HTT) have been implicated in impulsivity and related psychopathology. Yet it remains unclear the mechanism by which the 5-HTT genetic variants contribute to individual variability in impulse control. Here, we tested whether DMN connectivity mediates an association between the 5-HTT genetic variants and impulsivity...
April 21, 2017: Cerebral Cortex
https://www.readbyqxmd.com/read/28443534/developing-an-international-scoring-system-for-a-consensus-based-social-cognition-measure-msceit-managing-emotions
#9
G S Hellemann, M F Green, R S Kern, G Sitarenios, K H Nuechterlein
BACKGROUND: Measures of social cognition are increasingly being applied to psychopathology, including studies of schizophrenia and other psychotic disorders. Tests of social cognition present unique challenges for international adaptations. The Mayer-Salovey-Caruso Emotional Intelligence Test, Managing Emotions Branch (MSCEIT-ME) is a commonly-used social cognition test that involves the evaluation of social scenarios presented in vignettes. METHOD: This paper presents evaluations of translations of this test in six different languages based on representative samples from the relevant countries...
April 26, 2017: Psychological Medicine
https://www.readbyqxmd.com/read/28443039/primary-emotional-systems-and-personality-an-evolutionary-perspective
#10
Christian Montag, Jaak Panksepp
The present article highlights important concepts of personality including stability issues from the perspective of situational demands and stability over the life-course. Following this more introductory section, we argue why individual differences in primary emotional systems may represent the phylogenetically oldest parts of human personality. Our argumentation leads to the need to increasingly consider individual differences in the raw affects/emotions of people to understand human personality in a bottom-up fashion, which can be coordinated with top-down perspectives...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28441976/diversity-or-disarray-a-systematic-review-of-decision-making-capacity-for-treatment-and-research-in-schizophrenia-and-other-non-affective-psychoses
#11
B W J Spencer, G Shields, T Gergel, M Hotopf, G S Owen
BACKGROUND: Valid consent for treatment or research participation requires that an individual has decision-making capacity (DMC), which is the ability to make a specific decision. There is evidence that the psychopathology of schizophrenia can compromise DMC. The objective of this review was to examine the presence or absence of DMC in schizophrenia and the socio-demographic/psychopathological factors associated. METHODS: We searched three databases Embase, Ovid MEDLINE(R), and PsycINFO for studies reporting data on the proportion of DMC for treatment and research (DMC-T and DMC-R), and/or socio-demographic/psychopathological associations with ability to make such decisions, in people with schizophrenia and related illnesses...
April 26, 2017: Psychological Medicine
https://www.readbyqxmd.com/read/28441622/social-anxiety-and-disordered-eating-the-influence-of-stress-reactivity-and-self-esteem
#12
Jessica Lyn Ciarma, Jaya Miriam Mathew
While previous research indicates a strong link between social anxiety and disordered eating, more research is needed in order to understand the mechanisms that underlie this relationship. Given that stress is often implicated in disordered eating, it was hypothesised that ones reaction to stress (i.e. stress reactivity) would mediate the relationship between social anxiety and disordered eating. Similarly, given that low self-esteem is commonly reported in both those with social anxiety and eating disorders, it was hypothesised that self-esteem would also mediate the relationship between social anxiety and disordered eating...
April 8, 2017: Eating Behaviors
https://www.readbyqxmd.com/read/28441171/prevalence-of-psychopathology-in-children-of-parents-with-mental-illness-and-or-addiction-an-up-to-date-narrative-review
#13
Sophie Leijdesdorff, Karin van Doesum, Arne Popma, Rianne Klaassen, Therese van Amelsvoort
PURPOSE OF REVIEW: Children of parents with a mental illness and/or addiction are at high risk for developing a mental illness themselves. Parental mental illness is highly prevalent leading to a serious number of children at high risk. The aim of this review is to give an up-to-date overview of psychopathology in children of parents with various mental illnesses and/or addiction, based on recent literature. RECENT FINDINGS: Worldwide, 15-23% of children live with a parent with a mental illness...
April 22, 2017: Current Opinion in Psychiatry
https://www.readbyqxmd.com/read/28439899/parents-as-partners-a-u-k-trial-of-a-u-s-couples-based-parenting-intervention-for-at-risk-low-income-families
#14
Polly Casey, Philip A Cowan, Carolyn P Cowan, Lucy Draper, Naomi Mwamba, David Hewison
Despite the well-established links between couple relationship quality and healthy family functioning, and burgeoning evidence from the international intervention field, there is little or no evidence of the efficacy of couples-based interventions from the United Kingdom (U.K.). This study explored whether the Parents as Partners (PasP) program, a group-based intervention developed in the United States, brought about the same benefits in the U.K. The evaluation is based on 97 couples with children from communities with high levels of need, recruited to PasP because they are at high risk for parent and child psychopathology...
April 24, 2017: Family Process
https://www.readbyqxmd.com/read/28439771/neurobiological-programming-of-early-life-stress-functional-development-of-amygdala-prefrontal-circuitry-and-vulnerability-for-stress-related-psychopathology
#15
Michelle R VanTieghem, Nim Tottenham
Early adverse experiences are associated with heighted vulnerability for stress-related psychopathology across the lifespan. While extensive work has investigated the effects of early adversity on neurobiology in adulthood, developmental approaches can provide further insight on the neurobiological mechanisms that link early experiences and long-term mental health outcomes. In the current review, we discuss the role of emotion regulation circuitry implicated in stress-related psychopathology from a developmental and transdiagnostic perspective...
April 25, 2017: Current Topics in Behavioral Neurosciences
https://www.readbyqxmd.com/read/28439242/comprehensive-psychopathological-assessment-based-on-the-association-for-methodology-and-documentation-in-psychiatry-amdp-system-development-methodological-foundation-application-in-clinical-routine-and-research
#16
REVIEW
Rolf-Dieter Stieglitz, Achim Haug, Erdmann Fähndrich, Michael Rösler, Wolfgang Trabert
The documentation of psychopathology is core to the clinical practice of the psychiatrist and clinical psychologist. However, both in initial as well as further training and specialization in their fields, this particular aspect of their work receives scanty attention only. Yet, for the past 50 years, the Association for Methodology and Documentation in Psychiatry (AMDP) System has been in existence and available as a tool to serve precisely the purpose of offering a systematic introduction to the terminology and documentation of psychopathology...
2017: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/28439210/violence-in-context-embracing-an-ecological-approach-to-violent-media-exposure
#17
Erin Glackin, Sarah A O Gray
This commentary expands on Anderson, Bushman, Donnerstein, Hummer, and Warburton's agenda for minimizing the impacts of violent media exposure (VME) on youth aggression. We argue that in order to effectively intervene in the development of aggression and other maladaptive traits, researchers and policymakers should take an ecological, developmental psychopathology approach to understanding children's exposure to VME within developmental, relational, environmental, and cultural contexts. Such a framework holds the most promise for identifying at-risk groups, establishing targets of intervention, and testing mechanisms of change...
December 2016: Analyses of Social Issues and Public Policy: ASAP
https://www.readbyqxmd.com/read/28438245/bullying-and-the-detrimental-role-of-un-forgiveness-in-adolescents-wellbeing
#18
Barbara Barcaccia, Barry Howard Schneider, Susanna Pallini, Roberto Baiocco
BACKGROUND: Many studies have shown that victimisation by bullies is linked with psychopathology. Research has also demonstrated that forgiveness is associated with the mental health of victims of bullying. METHOD: Our objective was to explore the multiple components of forgiveness (i.e., benevolence, decreased avoidance of the perpetrator and diminished desire for revenge) as mediators of the negative mental health effects of bullying in Italian adolescents. Our hypothesis was that those who forgive their bullies would show lower levels of depression, state anger, and behaviour problems than those who did not forgive...
May 2017: Psicothema
https://www.readbyqxmd.com/read/28438241/alcohol-and-psychotropic-substance-use-in-female-spanish-victims-of-intimate-partner-violence
#19
María Crespo, Carmen Soberón, Violeta Fernández-Lansac, M M Gómez-Gutiérrez
BACKGROUND: Studies show high use of alcohol among American women who are victims of intimate partner violence (IPV), but not in Spanish victims. This study examines hazardous drinking, use of psychotropic substances, and the relationship with psychopathological symptoms in Spanish women who are victims of IPV. METHOD: 50 battered women and 50 control women from general population were assessed. RESULTS: Hazardous drinking in women victims of IPV (18...
May 2017: Psicothema
https://www.readbyqxmd.com/read/28438236/personal-and-macro-systemic-factors-as-predictors-of-quality-of-life-in-chronic-schizophrenia
#20
Yolanda Fontanil-Gómez, María A Alcedo Rodríguez, María I Gutiérrez López
BACKGROUND: The goal of this research was to establish possible predictive factors for both subjective and externally assessed quality of life in people with chronic schizophrenia. METHODS: Sixty-eight people with schizophrenia took part in the study and were assessed using the World Health Organisation Quality of Life Assessment - Brief Version (WHOQOL-BREF), the Quality of Life Scale (QLS), the Positive and Negative Syndrome Scale for Schizophrenia (PANSS), the Global Assessment of Functioning (GAF), the Social Functioning Scale (SFS) tests...
May 2017: Psicothema
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