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Food microbiology advancements

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https://www.readbyqxmd.com/read/27822524/from-sample-to-multi-omics-conclusions-in-under-48-hours
#1
Robert A Quinn, Jose A Navas-Molina, Embriette R Hyde, Se Jin Song, Yoshiki Vázquez-Baeza, Greg Humphrey, James Gaffney, Jeremiah J Minich, Alexey V Melnik, Jakob Herschend, Jeff DeReus, Austin Durant, Rachel J Dutton, Mahdieh Khosroheidari, Clifford Green, Ricardo da Silva, Pieter C Dorrestein, Rob Knight
Multi-omics methods have greatly advanced our understanding of the biological organism and its microbial associates. However, they are not routinely used in clinical or industrial applications, due to the length of time required to generate and analyze omics data. Here, we applied a novel integrated omics pipeline for the analysis of human and environmental samples in under 48 h. Human subjects that ferment their own foods provided swab samples from skin, feces, oral cavity, fermented foods, and household surfaces to assess the impact of home food fermentation on their microbial and chemical ecology...
March 2016: MSystems
https://www.readbyqxmd.com/read/27766214/an-overview-on-novel-microbial-determination-methods-in-pharmaceutical-and-food-quality-control
#2
Mahboob Nemati, Aliasghar Hamidi, Solmaz Maleki Dizaj, Vahid Javaherzadeh, Farzaneh Lotfipour
Traditional microbiological methods tend to be labor-intensive and time-consuming. Rapid and novel methods in microbiological tests provide more sensitive, precise and reproducible results compared with conventional methods. In microbiology, the most rapid testing methods belong to the field of biotechnology such as PCR, ELISA, ATP bioluminescence and etc. Nevertheless impedance microbiology, biosensors and analytical procedures to determine microbial constituents are of significance. The present review article was conducted using internet databases and related scientific literatures and articles that provide information on developments in the rapid methods in microbiology...
September 2016: Advanced Pharmaceutical Bulletin
https://www.readbyqxmd.com/read/27741154/an-advanced-in-vitro-technology-platform-to-study-the-mechanism-of-action-of-prebiotics-and-probiotics-in-the-gastrointestinal-tract
#3
Massimo Marzorati, Tom Van de Wiele
The gastrointestinal tract (GIT) hosts the most complex microbial community in the human body. Given the extensive metabolic potential which is present in this community, this additional organ is of key importance to maintain a healthy status and several diseases are frequently correlated with an alteration of the composition/functionality of the gut microbiota. Consequently, there is a great interest in identifying potential approaches that could modulate the microbiota and its metabolism to bring about a positive health effect...
November 2016: Journal of Clinical Gastroenterology
https://www.readbyqxmd.com/read/27713962/dietary-supplement-based-on-stilbenes-a-focus-on-gut-microbial-metabolism-by-the-in-vitro-simulator-m-shime%C3%A2
#4
Camilla Giuliani, Massimo Marzorati, Marzia Innocenti, Ramiro Vilchez-Vargas, Marius Vital, Dietmar H Pieper, Tom Van de Wiele, Nadia Mulinacci
Polyphenols and intestinal microbiota can influence each other, modifying metabolism and gut wellness. Data on this mutual effect need to be improved. Several studies on the biological activities of resveratrol and derivatives have been carried out, but the effects of a continuous administration of stilbenes on gut microbiota have not yet been investigated. This study evaluated the effects of an extract from Vitis vinifera, containing a combination of t-resveratrol and ε-viniferin, on intestinal microbiota, using the advanced gastrointestinal simulator M-SHIME®...
October 7, 2016: Food & Function
https://www.readbyqxmd.com/read/27639140/recent-trends-in-the-determination-of-biogenic-amines-in-fermented-beverages-a-review
#5
REVIEW
José Luis Ordóñez, Ana Maria Troncoso, Maria Del Carmen García-Parrilla, Raquel Maria Callejón
Biogenic amines (BA) are generally considered as a food hazard, even though there is not a threshold for these biomolecules in the European legislation, except for histamine in fishery products. These compounds are formed during the storage and processing of certain foods through microbiological activity, and when present in high concentrations, could have toxicological effects, causing health problems in consumers, especially to sensitive persons. This fact, in addition to the economical concern involved, makes it necessary to control the amounts of biogenic amines in foods...
October 5, 2016: Analytica Chimica Acta
https://www.readbyqxmd.com/read/27596399/use-of-spent-coffee-grounds-as-food-ingredient-in-bakery-products
#6
Nuria Martinez-Saez, Alba Tamargo García, Inés Domínguez Pérez, Miguel Rebollo-Hernanz, Marta Mesías, Francisco J Morales, María A Martín-Cabrejas, Maria Dolores Del Castillo
The present research aimed to evaluate the use of spent coffee grounds (SCG) from instant coffee as a food ingredient and its application in bakery products. Data on physicochemical characterization, thermal stability and food safety of SCG were acquired. Evaluation of feasibility as dietary fibre was also determined. Results showed SCG are natural source of antioxidant insoluble fibre, essential amino acids, low glycaemic sugars, resistant to thermal food processing and digestion process, and totally safe...
February 1, 2017: Food Chemistry
https://www.readbyqxmd.com/read/27551279/recent-advances-on-multi-parameter-flow-cytometry-to-characterize-antimicrobial-treatments
#7
REVIEW
Lucie Léonard, Lynda Bouarab Chibane, Balkis Ouled Bouhedda, Pascal Degraeve, Nadia Oulahal
The investigation on antimicrobial mechanisms is a challenging and crucial issue in the fields of food or clinical microbiology, as it constitutes a prerequisite to the development of new antimicrobial processes or compounds, as well as to anticipate phenomenon of microbial resistance. Nowadays it is accepted that a cells population exposed to a stress can cause the appearance of different cell populations and in particular sub-lethally compromised cells which could be defined as viable but non-culturable (VBNC)...
2016: Frontiers in Microbiology
https://www.readbyqxmd.com/read/27412586/individual-cell-heterogeneity-in-predictive-food-microbiology-challenges-in-predicting-a-noisy-world
#8
Konstantinos P Koutsoumanis, Zafiro Aspridou
Gene expression is a fundamentally noisy process giving rise to a significant cell to cell variability at the phenotype level. The phenotypic noise is manifested in a wide range of microbial traits. Heterogeneous behavior of individual cells is observed at the growth, survival and inactivation responses and should be taken into account in the context of Predictive Food Microbiology (PMF). Recent methodological advances can be employed for the study and modeling of single cell dynamics leading to a new generation of mechanistic models which can provide insight into the link between phenotype, gene-expression, protein and metabolic functional units at the single cell level...
January 2, 2017: International Journal of Food Microbiology
https://www.readbyqxmd.com/read/27357041/food-safety-practices-in-the-egg-products-industry
#9
Catherine L Viator, Sheryl C Cates, Shawn A Karns, Mary K Muth, Gary Noyes
We conducted a national census survey of egg product plants (n = 57) to obtain information on the technological and food safety practices of the egg products industry and to assess changes in these practices from 2004 to 2014. The questionnaire asked about operational and sanitation practices, microbiological testing practices, food safety training for employees, other food safety issues, and plant characteristics. The findings suggest that improvements were made in the industry's use of food safety technologies and practices between 2004 and 2014...
July 2016: Journal of Food Protection
https://www.readbyqxmd.com/read/27321680/genetically-modified-bacteriophages-in-applied-microbiology
#10
REVIEW
P Bárdy, R Pantůček, M Benešík, J Doškař
Bacteriophages represent a simple viral model of basic research with many possibilities for practical application. Due to their ability to infect and kill bacteria, their potential in the treatment of bacterial infection has been examined since their discovery. With advances in molecular biology and gene engineering, the phage application spectrum has been expanded to various medical and biotechnological fields. The construction of bacteriophages with an extended host range or longer viability in the mammalian bloodstream enhances their potential as an alternative to conventional antibiotic treatment...
September 2016: Journal of Applied Microbiology
https://www.readbyqxmd.com/read/27155661/structure-function-relationships-of-family-gh70-glucansucrase-and-4-6-%C3%AE-glucanotransferase-enzymes-and-their-evolutionary-relationships-with-family-gh13-enzymes
#11
REVIEW
Xiangfeng Meng, Joana Gangoiti, Yuxiang Bai, Tjaard Pijning, Sander S Van Leeuwen, Lubbert Dijkhuizen
Lactic acid bacteria (LAB) are known to produce large amounts of α-glucan exopolysaccharides. Family GH70 glucansucrase (GS) enzymes catalyze the synthesis of these α-glucans from sucrose. The elucidation of the crystal structures of representative GS enzymes has advanced our understanding of their reaction mechanism, especially structural features determining their linkage specificity. In addition, with the increase of genome sequencing, more and more GS enzymes are identified and characterized. Together, such knowledge may promote the synthesis of α-glucans with desired structures and properties from sucrose...
July 2016: Cellular and Molecular Life Sciences: CMLS
https://www.readbyqxmd.com/read/27060534/high-pressure-effects-on-the-structural-functionality-of-condensed-globular-protein-matrices
#12
Sobhan Savadkoohi, Stefan Kasapis
High pressure technology is the outcome of consumer demand for better quality control of processed foods. There is great potential to apply HPP to condensed systems of globular proteins for the generation of industry-relevant biomaterials with advanced techno- and biofunctionality. To this end, research demonstrates that application of high hydrostatic pressure generates a coherent structure and preserves the native conformation in condensed globular proteins, which is an entirely unexpected but interesting outcome on both scientific and technological grounds...
July 2016: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/27041363/recent-and-emerging-innovations-in-salmonella-detection-a-food-and-environmental-perspective
#13
REVIEW
Rebecca L Bell, Karen G Jarvis, Andrea R Ottesen, Melinda A McFarland, Eric W Brown
Salmonella is a diverse genus of Gram-negative bacilli and a major foodborne pathogen responsible for more than a million illnesses annually in the United States alone. Rapid, reliable detection and identification of this pathogen in food and environmental sources is key to safeguarding the food supply. Traditional microbiological culture techniques have been the 'gold standard' for State and Federal regulators. Unfortunately, the time to result is too long to effectively monitor foodstuffs, especially those with very short shelf lives...
May 2016: Microbial Biotechnology
https://www.readbyqxmd.com/read/26818996/combating-antimicrobial-resistance-in-foodborne-microorganisms
#14
Edward P C Lai, Zafar Iqbal, Tyler J Avis
This review addresses an important public health hazard affecting food safety. Antimicrobial agents are used in foods to reduce or eliminate microorganisms that cause disease. Many traditional organic compounds, novel synthetic organic agents, natural products, peptides, and proteins have been extensively studied for their effectiveness as antimicrobial agents against foodborne Campylobacter spp., Escherichia coli, Listeria spp. and Salmonella. However, antimicrobial resistance can develop in microorganisms, enhancing their ability to withstand the inhibiting or killing action of antimicrobial agents...
February 2016: Journal of Food Protection
https://www.readbyqxmd.com/read/26735573/the-effects-of-mandatory-haccp-implementation-on-microbiological-indicators-of-process-hygiene-in-meat-processing-and-retail-establishments-in-serbia
#15
Igor Tomasevic, Jelena Kuzmanović, Aleksandra Anđelković, Miroslava Saračević, Marija M Stojanović, Ilija Djekic
A total of 48,246 microbiological test results were collected from 130 meat processing plants and 220 meat retail facilities over a seven year period: 41 months before and 43 months after HACCP implementation. Our results confirm a strong positive effect of mandatory HACCP implementation on process hygiene indicators in meat establishments. Significant reductions were observed in the number of hygiene indicator organisms on all types of surfaces examined and types of meat establishments investigated. The improvement of process hygiene was articulated as aerobic colony count reduction of at least 1...
April 2016: Meat Science
https://www.readbyqxmd.com/read/26682454/hybrid-carbon-based-nanostructured-platforms-for-the-advanced-bioreactors
#16
I Levchenko, A Mai-Prochnow, S Yick, M M M Bilek, A Kondyurin, Z J Han, J Fang, U Cvelbar, D Mariotti, K Ostrikov
Mankind faces several global challenges such as chronic and acute hunger, global poverty, energy deficiency and environment conservation. Common biotechnologies based on batch, fluidbed and other similar processes are now extensively used for the production of a wide range of products such as antibiotics, biofuels, cultured and fermented food products. Unfortunately, these processes suffer from low efficiency, high energy demand, low controllability and rapid biocatalyst degradation by microbiological attack, and thus still are not capable of seriously addressing the global hunger and energy deficiency challenges...
December 2015: Journal of Nanoscience and Nanotechnology
https://www.readbyqxmd.com/read/26386062/application-of-metagenomic-sequencing-to-food-safety-detection-of-shiga-toxin-producing-escherichia-coli-on-fresh-bagged-spinach
#17
Susan R Leonard, Mark K Mammel, David W Lacher, Christopher A Elkins
Culture-independent diagnostics reduce the reliance on traditional (and slower) culture-based methodologies. Here we capitalize on advances in next-generation sequencing (NGS) to apply this approach to food pathogen detection utilizing NGS as an analytical tool. In this study, spiking spinach with Shiga toxin-producing Escherichia coli (STEC) following an established FDA culture-based protocol was used in conjunction with shotgun metagenomic sequencing to determine the limits of detection, sensitivity, and specificity levels and to obtain information on the microbiology of the protocol...
December 2015: Applied and Environmental Microbiology
https://www.readbyqxmd.com/read/26342014/the-stomach-in-health-and-disease
#18
REVIEW
R H Hunt, M Camilleri, S E Crowe, E M El-Omar, J G Fox, E J Kuipers, P Malfertheiner, K E L McColl, D M Pritchard, M Rugge, A Sonnenberg, K Sugano, J Tack
The stomach is traditionally regarded as a hollow muscular sac that initiates the second phase of digestion. Yet this simple view ignores the fact that it is the most sophisticated endocrine organ with unique physiology, biochemistry, immunology and microbiology. All ingested materials, including our nutrition, have to negotiate this organ first, and as such, the stomach is arguably the most important segment within the GI tract. The unique biological function of gastric acid secretion not only initiates the digestive process but also acts as a first line of defence against food-borne microbes...
October 2015: Gut
https://www.readbyqxmd.com/read/26224771/strategic-regulatory-evaluation-and-endorsement-of-the-hollow-fiber-tuberculosis-system-as-a-novel-drug-development-tool
#19
Klaus Romero, Robert Clay, Debra Hanna
The first nonclinical drug development tool (DDT) advanced by the Critical Path to TB Drug Regimens (CPTR) Initiative through a regulatory review process has been endorsed by leading global regulatory authorities. DDTs with demonstrated predictive accuracy for clinical and microbiological outcomes are needed to support decision making. Regulatory endorsement of these DDTs is critical for drug developers, as it promotes confidence in their use in Investigational New Drug and New Drug Application filings. The in vitro hollow fiber system model of tuberculosis (HFS-TB) is able to recapitulate concentration-time profiles (exposure) observed in patients for single drugs and combinations, by evaluating exposure measures for the ability to kill tuberculosis in different physiologic conditions...
August 15, 2015: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/26173190/tedizolid-a-new-oxazolidinone-antibiotic-for-skin-and-soft-tissue-infections
#20
REVIEW
Elias B Chahine, Allana J Sucher, Shannon D Knutsen
OBJECTIVE: To review the chemistry, pharmacology, microbiology, pharmacodynamics, pharmacokinetics, clinical efficacy, tolerability, drug interactions, dosing, and administration of tedizolid phosphate (TDZ). DATA SOURCES: A search of PubMed using the terms "tedizolid," "torezolid," "TR-701," "TR-700," "DA-7157," and "DA-7218" was performed. The manufacturer's Web site was also reviewed to further identify relevant information. STUDY SELECTION: All English-language articles from 2006 to November 2014 appearing in these searches were reviewed for relevance to this paper...
July 2015: Consultant Pharmacist: the Journal of the American Society of Consultant Pharmacists
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