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https://www.readbyqxmd.com/read/27921426/-gestational-diabetes-mellitus
#1
Hana Krejčí
The present generation of women of childbearing age more frequently suffer from overweight, obesity, initial as well as fully established metabolic syndrome, which together with postponing motherhood until the third decade in life plays an important role in the increasing incidence of gestational diabetes (GDM) that currently affects about 1/5 of pregnant women. However the causal link between diabetes during pregnancy and metabolic diseases in the whole population is mutual. By way of epigenetic changes, maternal diabetes unfavourably programmes metabolism of the offspring, who tend to transfer the disorder to the next generations...
2016: Vnitr̆ní Lékar̆ství
https://www.readbyqxmd.com/read/27921380/induction-of-labour-for-suspected-macrosomia-at-term-in-non-diabetic-women-a-systematic-review-and-meta-analysis-of-randomized-controlled-trials
#2
REVIEW
E R Magro-Malosso, G Saccone, M Chen, R Navathe, M Di Tommaso, V Berghella
BACKGROUND: Several randomized controlled trials (RCTs) compared induction of labour with expectant management in non-diabetic women with suspected fetal macrosomia. OBJECTIVE: To evaluate the effects of labour induction for suspected fetal macrosomia. SEARCH STRATEGY: Literature search in electronic databases. SELECTION CRITERIA: We included all RCTs of suspected fetal macrosomia comparing labour induction with expectant management in term pregnancy...
December 5, 2016: BJOG: An International Journal of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/27921038/the-clinical-manifestation-and-management-of-autosomal-dominant-polycystic-kidney-disease-in-china
#3
REVIEW
Cheng Xue, Chen-Chen Zhou, Ming Wu, Chang-Lin Mei
BACKGROUND: Autosomal dominant polycystic kidney disease (ADPKD) is the most common monogenic hereditary kidney disease characterized by progressive enlargement of renal cysts. The incidence is 1-2‰ worldwide. Mutations in two genes (PKD1 and PKD2) cause ADPKD. Currently, there is no pharmaceutical treatment available for ADPKD patients in China. Summary: This review focused on advances in clinical manifestation, gene diagnosis, risk factors, and management of ADPKD in China. There is an age-dependent increase in total kidney volume (TKV) and decrease in renal function in Chinese ADPKD patients...
October 2016: Kidney Diseases
https://www.readbyqxmd.com/read/27921037/acute-kidney-injury-in-western-countries
#4
REVIEW
Josée Bouchard, Ravindra L Mehta
BACKGROUND: Acute kidney injury (AKI) is frequent and is associated with poor outcomes, including increased mortality, higher risk of chronic kidney disease, and prolonged hospital lengths of stay. The epidemiology of AKI mainly derives from studies performed in Western high-income countries. More limited data are available from Western low-income and middle-income countries (LMICs) located in Central and South America. SUMMARY: In this review, we summarize the most recent data on the epidemiology of AKI in Western countries, aiming to contrast results from industrialized high-income countries with LMICs...
October 2016: Kidney Diseases
https://www.readbyqxmd.com/read/27921036/acute-kidney-injury-in-asia
#5
REVIEW
Li Yang
BACKGROUND: Acute kidney injury (AKI) is a common disorder and is associated with a high morbidity and mortality worldwide. The diversity of the climate and of the socioeconomic and developmental status in Asia has a great influence on the etiology and presentation of AKI in different regions. In view of the International Society of Nephrology's 0by25 initiative, more and more attention has been paid to AKI in Asian countries. SUMMARY: In this review, we summarize the recent achievements with regard to the prevalence and clinical patterns of AKI in Asian countries...
October 2016: Kidney Diseases
https://www.readbyqxmd.com/read/27920867/glenoid-hypoplasia
#6
Mauricio J Baca, Ryan W King, Laura W Bancroft
Glenoid hypoplasia, also known as glenoid dysplasia and dysplasia of the scapular neck, is a failure of ossification of the posteroinferior two-thirds of the glenoid. Once thought to be a rare condition, more recent studies have shown that the incidence of glenoid hypoplasia ranges from 18% to 35%. This case report and literature review highlights the typical clinical presentation, the radiologic findings, and the management options for patients with glenoid hypoplasia.
December 2016: Radiology case reports
https://www.readbyqxmd.com/read/27920572/home-peripheral-nerve-catheters-the-first-24-months-of-experience-at-a-children-s-hospital
#7
Andrew Gable, Candice Burrier, Jenna Stevens, Sharon Wrona, Kevin Klingele, Tarun Bhalla, David P Martin, Giorgio Veneziano, Joseph D Tobias
CONTEXT: Home peripheral nerve catheters (PNCs) have become common practice for adult patients after major orthopedic surgery. However, use in pediatric patients is a recent application. OBJECTIVES: The purpose of this study was to review the demographics and outcomes of pediatric patients receiving a PNC at our institution. METHODS: This retrospective study included patients from October 2012 through October 2014 undergoing orthopedic procedures with a PNC placed for postoperative pain management...
2016: Journal of Pain Research
https://www.readbyqxmd.com/read/27920492/flap-double-twist-technique-for-prevention-of-lasik-flap-striae
#8
Karim Mahmoud Nabil
A novel flap double twist technique was applied to reduce the incidence of post-laser-assisted in situ keratomileusis (LASIK) flap striae. The flap is floated and stroked in the same way as is done for management of first postoperative day striae, where the method is to float and irrigate the flap into position, followed by applying gentle pressure on the flap with a wet Merocel microsponge and moving the flap away from the hinge position. The sponge is then manually squeezed to become drier, and the flap is continuously stroked in a direction opposite to the hinge...
2016: Clinical Ophthalmology
https://www.readbyqxmd.com/read/27920066/new-concepts-for-an-old-problem-the-diagnosis-of-endometrial-hyperplasia
#9
REVIEW
Peter A Sanderson, Hilary O D Critchley, Alistair R W Williams, Mark J Arends, Philippa T K Saunders
BACKGROUND: Endometrial hyperplasia (EH) is a uterine pathology representing a spectrum of morphological endometrial alterations. It is predominantly characterized by an increase in the endometrial gland-to-stroma ratio when compared to normal proliferative endometrium. The clinical significance of EH lies in the associated risk of progression to endometrioid endometrial cancer (EC) and 'atypical' forms of EH are regarded as premalignant lesions. Traditional histopathological classification systems for EH exhibit wide and varying degrees of diagnostic reproducibility and, as a consequence, standardized patient management can be challenging...
December 4, 2016: Human Reproduction Update
https://www.readbyqxmd.com/read/27919996/prognostic-influence-of-internal-mammary-node-drainage-in-patients-with-early-stage-breast-cancer
#10
Lucie Lukesova, David Vrana, Ivan Svach, Nora Zlamalova, Jiri Gatek, Zuzana Vlachová, Marcel Matzenauer, Pavel Koranda, Klara Hruzova, Tomas Tichy, Bohuslav Melichar
BACKGROUND: The management of internal mammary nodes (IMNs) during multidisciplinary treatment of breast cancer has been debated for the last four decades without unequivocal conclusion. PATIENTS AND METHODS: We retrospectively reviewed patients with breast cancer who underwent sentinel lymph node biopsy at our center from 2008 until 2012. IMN drainage was assessed as a potential risk factor for local and distant disease recurrence. RESULTS: We identified 712 patients, with incidence of drainage to IMNs of 18...
December 2016: Anticancer Research
https://www.readbyqxmd.com/read/27919478/attitudes-to-cannabis-and-patterns-of-use-among-canadians-with-multiple-sclerosis
#11
Emma Banwell, Bennis Pavisian, Liesly Lee, Anthony Feinstein
BACKGROUND: Canada has the highest incidence of MS worldwide. Anecdotal evidence reveals that people with MS smoke, ingest or vaporize cannabis for a multiplicity of reasons. With the legal situation in relation to use currently in flux, we undertook a study investigating patterns of use amongst people with MS and their attitudes towards the drug. METHODS: A consecutive sample of people with MS (n=246) attending a neurology (n=118) and a neuropsychiatry (n=107) clinic was enrolled and asked to complete a questionnaire containing demographic, disease and cannabis related variables...
November 2016: Multiple Sclerosis and related Disorders
https://www.readbyqxmd.com/read/27918744/efficacy-of-naproxen-with-or-without-esomeprazole-for-pain-and-inflammation-in-patients-after-bilateral-third-molar-extractions-a-double-blinded-crossover-study
#12
G-M Weckwerth, L-F Simoneti, P Zupelari-Gonçalves, A-M Calvo, D-T Brozoski, T-J Dionísio, E-A Torres, J-R Lauris, F-A Faria, C-F Santos
BACKGROUND: Using a double-blinded randomized crossover design, this study aimed to evaluate acute postoperative pain management, swelling and trismus in 46 volunteers undergoing extractions of the two lower third molars, in similar positions, at two different appointments who consumed a tablet of either NE (naproxen 500 mg + esomepraz ole 20 mg) or only naproxen (500 mg) every 12 hours for 4 days. MATERIAL AND METHODS: Parameters were analyzed: self-reported pain intensity using a visual analog scale (VAS) pre- and postoperative mouth opening; incidence, type and severity of adverse reactions; total quantity consumed of rescue medication; and pre- and postoperative swelling...
December 6, 2016: Medicina Oral, Patología Oral y Cirugía Bucal
https://www.readbyqxmd.com/read/27918375/treatments-and-other-prognostic-factors-in-the-management-of-the-open-abdomen-a-systematic-review
#13
Adam T Cristaudo, Scott B Jennings, Kerry Hitos, Ronny Gunnarsson, Alan DeCosta
BACKGROUND: The open abdomen (OA) is an important approach for managing intra-abdominal catastrophes and continues to be the standard of care. Despite this, challenges remain with it associated with a high incidence of complications and poor outcomes. The objective of this article is to perform a systematic review in accordance with PRISMA guidelines to identify prognostic factors in OA patients in regards to definitive fascial closure (DFC), mortality and intra-abdominal complications...
November 30, 2016: Journal of Trauma and Acute Care Surgery
https://www.readbyqxmd.com/read/27918333/effectiveness-of-epidural-analgesia-continuous-surgical-site-analgesia-and-patient-controlled-analgesic-morphine-for-postoperative-pain-management-and-hyperalgesia-rehabilitation-and-health-related-quality-of-life-after-open-nephrectomy-a-prospective-randomized
#14
Xavier Capdevila, Sebastien Moulard, Christian Plasse, Jean-Luc Peshaud, Nicolas Molinari, Christophe Dadure, Sophie Bringuier
BACKGROUND: There is no widely recognized effective technique to optimally reduce pain scores and prevent persistent postoperative pain after nephrectomy. We compared continuous surgical site analgesia (CSSA), epidural analgesia (EA), and a control group (patient-controlled analgesic morphine) in patients undergoing open nephrectomy. METHODS: Sixty consecutive patients were randomized to be part of EA, CSSA, or control groups postoperatively for 72 hours. All patients received patient-controlled analgesic morphine, if needed...
December 1, 2016: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/27918156/-cesarean-section-incidence-and-vaginal-birth-success-rate-at-term-pregnancy-after-myomectomy
#15
L Mekiňová, P Janků, E Filipinská, J Kadlecová, P Ventruba
OBJECTIVE: To compare the incidence of primary and acute cesarean section (CS) and to compare success rate of vaginal delivery. To determine the frequency of maternal complications and evaluation of post-partum condition of the newborn. STUDY DESIGN: Prospective, pilot, cohort study. SETTING: Department of Gynecology and Obstetrics Masaryk University and University Hospital Brno. METHODS: Analysis of patients with physiologically ongoing singleton pregnancy and term delivery, vertex presentation...
2016: Ceská Gynekologie
https://www.readbyqxmd.com/read/27918068/temporal-trends-and-outcomes-associated-with-atrial-fibrillation-observed-during-acute-coronary-syndrome-real-world-data-from-the-acute-coronary-syndrome-israeli-survey-acsis-2000-2013
#16
Aharon Erez, Ilan Goldenberg, Avi Sabbag, Eyal Nof, Doron Zahger, Shaul Atar, Arthur Pollak, Idit Dobrecky-Merye, Roy Beigel, Shlomi Matetzky, Michael Glikson, Roy Beinart
BACKGROUND: The past decade has brought major advances in therapy of patients presenting with acute coronary syndromes (ACS). HYPOTHESIS: The outcomes of ACS patients with atrial fibrillation (AF) has improved over the years. METHODS: We evaluated time-dependent changes in clinical characteristics, management strategies, and outcomes associated with AF observed during ACS hospitalization in patients enrolled in the biannual ACS Israeli Surveys (ACSIS) between 2000 and 2013...
December 5, 2016: Clinical Cardiology
https://www.readbyqxmd.com/read/27917732/olfactory-neuroblastoma-14-year-experience-at-an-australian-tertiary-centre-and-the-role-for-longer-term-surveillance
#17
C Schmidt, N Potter, S Porceddu, B Panizza
BACKGROUND: Olfactory neuroblastoma is a rare sinonasal malignancy, with poorly defined treatment protocols. Management at a tertiary centre was retrospectively evaluated to inform future treatment and follow up. METHODS: Cases treated with curative intent (2000-2014) were included. Data were collected, and overall and disease-free survival rates were calculated. RESULTS: Eleven cases were identified, with a median follow up of 87 months. One patient was Kadish stage A, one was stage B, eight were stage C and one was stage D...
December 5, 2016: Journal of Laryngology and Otology
https://www.readbyqxmd.com/read/27917377/incident-management-systems-are-essential-for-effective-coordination-of-large-disease-outbreaks-perspectives-from-the-coordination-of-the-ebola-outbreak-response-in-sierra-leone
#18
Olushayo Oluseun Olu, Margaret Lamunu, Alexander Chimbaru, Ayotunde Adegboyega, Ishata Conteh, Ngoy Nsenga, Noah Sempiira, Kande-Bure Kamara, Foday Mohamed Dafae
BACKGROUND: Response to the 2014-2015 Ebola virus disease (EVD) outbreak in Sierra Leone overwhelmed the national capacity to contain it and necessitated a massive international response and strong coordination platform. Consequently, the Sierra Leone Government, with support of the international humanitarian community, established and implemented various models for national coordination of the outbreak. In this article, we review the strengths and limitations of the EVD outbreak response coordination systems in Sierra Leone and propose recommendations for improving coordination of similar outbreaks in the future...
2016: Frontiers in Public Health
https://www.readbyqxmd.com/read/27917075/management-of-clostridium-difficile-infection
#19
Layth S Al-Jashaami, Herbert L DuPont
Since the discovery of Clostridium difficile infection (CDI) in the 1970s, there has been an increase in the incidence, severity, and recurrence rate of the disease. We reviewed the recent CDI literature in PubMed published before February 28, 2016 that focused on advances in therapy. Despite a large number of studies describing methods for diagnosing the disease, there is currently no definitive test that identifies this infection with certainty, which complicates therapy. Recommended therapy for CDI includes oral metronidazole for mild cases and oral vancomycin or fidaxomicin for moderate to severe cases, each given for 10 to 14 days...
October 2016: Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/27916581/use-of-a-tick-borne-disease-manual-increases-accuracy-of-tick-identification-among-primary-care-providers-in-lyme-disease-endemic-areas
#20
Amber D Butler, Meredith L Carlson, Christina A Nelson
Given the high incidence of tick bites and tick-borne diseases in the United States, it is important for primary care providers to recognize common ticks and the pathogens they may transmit. If a patient has removed and saved an attached tick, identifying the tick helps guide clinical management and determine whether antibiotic prophylaxis for Lyme disease is appropriate. To investigate providers' ability to recognize common ticks and the pathogens they may transmit, we asked 76 primary care providers from Lyme disease endemic areas to identify the common name or genus of preserved ticks found in their area...
November 23, 2016: Ticks and Tick-borne Diseases
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