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Colon diverticules

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https://www.readbyqxmd.com/read/28634524/a-rare-case-of-pylephlebitis-after-colonic-polypectomy
#1
Salik Nazir, Asad Jehangir, Anam Siddiqui, Niranjan Tachamo, Saroj Lohani, Eugene York
Pylephlebitis or infective suppurative thrombosis of the portal mesenteric venous system is an uncommon condition that can potentially be deadly if not recognized and treated early. Although most commonly associated with pancreatitis and diverticulitis, any intra-abdominal or pelvic infection occurring in the region drained by the portal venous system can cause this rare entity. We report a case of a 75-year-old woman who developed post polypectomy pylephlebitis following colonoscopy, a condition rarely reported in the literature...
January 2017: Journal of Community Hospital Internal Medicine Perspectives
https://www.readbyqxmd.com/read/28631827/one-year-results-of-the-scandiv-randomized-clinical-trial-of-laparoscopic-lavage-versus-primary-resection-for-acute-perforated-diverticulitis
#2
J K Schultz, C Wallon, L Blecic, H M Forsmo, J Folkesson, P Buchwald, H Kørner, F A Dahl, T Øresland, S Yaqub
BACKGROUND: Recent randomized trials demonstrated that laparoscopic lavage compared with resection for Hinchey III perforated diverticulitis was associated with similar mortality, less stoma formation but a higher rate of early reintervention. The aim of this study was to compare 1-year outcomes in patients who participated in the randomized Scandinavian Diverticulitis (SCANDIV) trial. METHODS: Between February 2010 and June 2014, patients from 21 hospitals in Norway and Sweden presenting with suspected perforated diverticulitis were enrolled in a multicentre RCT comparing laparoscopic lavage and sigmoid resection...
June 20, 2017: British Journal of Surgery
https://www.readbyqxmd.com/read/28627445/right-sided-acute-diverticulitis-a-single-western-center-experience
#3
Francesco Monari, Maurizio Cervellera, Basilio Pirrera, Umberto D'Errico, Samuele Vaccari, Laura Alberici, Valeria Tonini
INTRODUCTION: Right sided diverticular disease is a rare condition in Western countries whereas is common amongst Asian population. The aim of this study is to evaluate options and outcomes for the treatment of right colonic diverticulitis. METHOD: We included only patients undergoing surgery with right colon diverticulitis (RCD) proven at histological specimen examination from September 2011 to December 2016. RESULTS: We performed 18 operations for RCD...
June 13, 2017: International Journal of Surgery
https://www.readbyqxmd.com/read/28625560/small-bowel-ultrasound-beyond-inflammatory-bowel-disease-an-updated-review-of-the-recent-literature
#4
REVIEW
Federica Cavalcoli, Alessandra Zilli, Mirella Fraquelli, Dario Conte, Sara Massironi
The use of bowel ultrasonography (US) for the evaluation of gut diseases has increased in recent years and has been proven to provide a widely available, non-invasive and inexpensive method for the initial work-up and follow-up of different intestinal diseases, limited mostly by technical challenges posed by the patient's anatomy. The present review aims to provide an extensive overview of the main pathologic features at US examination of intestinal diseases other than inflammatory bowel disease, both acute (e...
June 15, 2017: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/28623877/5-aminosalicylic-acid-agents-for-prevention-of-recurrent-diverticulitis-a-systematic-review-and-meta-analysis
#5
Seigo Urushidani, Akira Kuriyama, Masami Matsumura
BACKGROUND AND AIM: Prevalence of colonic diverticulosis is increasing worldwide with age, and up to 25% of patients who have colonic diverticulosis might experience diverticulitis. However, a definitive approach of preventing recurrent diverticulitis remains unknown. 5-aminosalicylic acid (5-ASA) agents are anti-inflammatory agents and have been used to prevent recurrent diverticulitis, and there have been some randomized, clinical trials (RCTs). However, the efficacy results for secondary prevention in uncomplicated diverticulitis differed across studies...
June 17, 2017: Journal of Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/28619727/rna-seq-implicates-deregulation-of-the-immune-system-in-the-pathogenesis-of-diverticulitis
#6
Kathleen M Schieffer, Christine S Choi, Scott Emrich, Leonard Harris, Sue Deiling, Dipti M Karamchandani, Anna Salzberg, Yuka I Kawasawa, Gregory S Yochum, Walter A Koltun
Individuals with diverticula or outpouchings of the colonic mucosa and submucosa through the colonic wall have diverticulosis, which is usually asymptomatic. In 10-25% of individuals, the diverticula become inflamed, resulting in diverticulitis. Very little is known about the pathophysiology or gene regulatory pathways involved in the development of diverticulitis. To identify these pathways, we deep sequenced RNAs isolated from full-thickness sections of sigmoid colon from diverticulitis patients and control individuals...
June 15, 2017: American Journal of Physiology. Gastrointestinal and Liver Physiology
https://www.readbyqxmd.com/read/28611980/there-is-no-role-for-colonoscopy-after-diverticulitis-among-asian-patients-less-than-50-years-of-age
#7
Dedrick Kok Hong Chan, Ker-Kan Tan
BACKGROUND: Colonoscopy is advocated following acute diverticulitis to ensure that malignancy is not missed. In an Asian population, diverticulitis is more common in the right colon and in younger patients. The purpose of this study is to examine the utility of colonoscopy amongst Asian patients <50 years of age who have had colonic diverticulitis. METHODS: A retrospective review of all patients aged 50 years and under who were treated for colonic diverticulitis between 2012 and 2014 was performed...
March 2017: Gastrointestinal Tumors
https://www.readbyqxmd.com/read/28608041/laparoscopic-lavage-in-the-management-of-perforated-diverticulitis-a-contemporary-meta-analysis
#8
Norman Galbraith, Jane V Carter, Uri Netz, Dongyan Yang, Donald E Fry, Michael McCafferty, Susan Galandiuk
IMPORTANCE: Perforated diverticulitis carries the risk of significant comorbidity and mortality. Although colon resection provides adequate source control, the procedure itself carries morbidity, as well as later stoma reversal procedures. The effectiveness of laparoscopic lavage to treat perforated diverticulitis remains unclear. OBJECTIVE: We aimed to conduct a meta-analysis to evaluate current studies comparing laparoscopic lavage with colon resection in cases of perforated diverticulitis for the effectiveness in source control, without the need for subsequent interventions, stoma formation, and death...
June 12, 2017: Journal of Gastrointestinal Surgery: Official Journal of the Society for Surgery of the Alimentary Tract
https://www.readbyqxmd.com/read/28595269/identification-of-a-rare-lamb4-variant-associated-with-familial-diverticulitis-through-exome-sequencing
#9
Joel L Coble, Kathryn Sheldon, Feng Yue, Tarik Salameh, Leonard Harris, Sue Deiling, Francesca Ruggiero, Melanie Eshelman, Gregory S Yochum, Walter A Koltun, Glenn S Gerhard, James R Broach
Diverticulitis is a chronic disease of the colon in which diverticuli, or outpouching through the colonic wall, become inflamed. Although recent observations suggests that genetic factors may play a significant role in diverticulitis, few genes have yet been implicated in disease pathogenesis and familial cases are uncommon. Here, we report results of whole exome sequencing performed on members from a single multi-generational family with early onset diverticulitis in order to identify a genetic component of the disease...
June 8, 2017: Human Molecular Genetics
https://www.readbyqxmd.com/read/28590294/colonic-parasitic-infection-mimicking-peritoneal-seeding-on-18f-fdg-pet-ct
#10
Beong Woo Kim, Hae Won Kim, Kyoung Sook Won, Yu-Na Kang, Byung-Wook Choi
A 77-year-old man with anorexia and weight loss for 6 months received a diagnosis of gastric cancer by endoscopy and referred for F-FDG PET/CT for initial staging. F-FDG PET/CT showed multiple foci of increased FDG uptake with diffuse wall thickening and multiple diverticula. The differential diagnoses were peritoneal seeding and multiple diverticulitis. The patient underwent curative total gastrectomy, and the lesion was diagnosed as poorly differentiated adenocarcinoma by histological examination. He underwent anterior resection of the sigmoid colon for exploration...
June 5, 2017: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/28586045/low-htra1-expression-in-patients-with-long%C3%A2-standing-ulcerative-colitis-and-colorectal-cancer
#11
Emma Altobelli, Giovanni Latella, Manrico Morroni, Caterina Licini, Giovanni Tossetta, Roberta Mazzucchelli, Valerio F Profeta, Gino Coletti, Pietro Leocata, Mario Castellucci, Mario Guerrieri, Reimondo Petrocelli, Berardo De Berardis, Marina De Padova, Gabriella Di Leonardo, Antonella Paladini, Filippo Mignosi, Gina Quaglione, Roberto Fagnano, Daniela Marzioni
The association between inflammatory bowel disease (IBD) and colorectal cancer (CRC) is being increasingly investigated. HtrA1 overexpression inhibits cell growth and proliferation by influencing apoptosis, invasiveness and migration of tumour cells. In the present study, HtrA1 expression was analysed in 228 colon tissue samples from patients with CRC, adenoma with high-grade dysplasia (AHD), adenoma with low-grade dysplasia (ALD), ulcerative colitis of >10 year duration (UCL), ulcerative colitis of <5 year duration (UCS) and colonic diverticulitis (D), and was compared with its expression in normal colon tissues (NCTs) collected 5 cm from the CRC lesion and in healthy colon mucosa (HC), to establish whether HtrA1 can serve as a biomarker for these conditions...
June 6, 2017: Oncology Reports
https://www.readbyqxmd.com/read/28565789/abdominal-ultrasonography-for-patients-with-abdominal-pain-as-a-first-line-diagnostic-imaging-modality
#12
Minoru Tomizawa, Fuminobu Shinozaki, Rumiko Hasegawa, Yoshinori Shirai, Yasufumi Motoyoshi, Takao Sugiyama, Shigenori Yamamoto, Naoki Ishige
The utility and limitations of abdominal ultrasonography (US) were retrospectively evaluated as a first-line diagnostic imaging modality in patients with abdominal pain. Hospital records from patients subjected to abdominal US as a first-line diagnostic imaging examination at the National Hospital Organization Shimoshizu Hospital (Yotsukaido, Japan) from April 2010 to April 2015 were analyzed. Only those patients who underwent abdominal US to diagnose abdominal symptoms were included in the present study. All patients with prior diagnostic imaging examination findings were excluded from the study in order to reduce bias of results...
May 2017: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/28557372/laparoscopic-sigmoidectomy-combined-with-uterus-excision-for-colouterine-fistula-caused-by-sigmoid-colon-diverticulitis-a-case-report
#13
Satoshi Arakawa, Zenichi Morise, Masashi Isetani, Hirokazu Tomishige, Norihiko Kawabe, Hidetoshi Nagata, Yukio Asano, Jin Kawase, Kenshiro Kamio, Yoshihiro Imaeda, Shunji Umemoto, Masahiro Ikeda, Akihiko Horiguchi
A case of colouterine fistula caused by colonic diverticulitis that was successfully treated laparoscopically is presented. A 74-year-old woman visited us with lower abdominal discomfort and vaginal excretion with minor fecal contamination. Mild tenderness was observed in her lower abdomen. Blood examinations revealed elevated white blood cell count and C-reactive protein. Sigmoid colon diverticulitis was revealed on CT, and her condition was diagnosed as colouterine fistula. Hinchey classification was stage I...
May 29, 2017: Asian Journal of Endoscopic Surgery
https://www.readbyqxmd.com/read/28555444/diverticulitis-recurrence-after-percutaneous-abscess-drainage
#14
REVIEW
Tarek Jalouta, Nezar Jrebi, Martin Luchtefeld, James W Ogilvie
PURPOSE: Recurrent diverticulitis has been reported in 30-50% of patients who recover from an episode of diverticular-associated abscess. Our aim was to review the outcomes of patients who underwent non-operative management after percutaneous drainage (PD) of colonic diverticular abscess. METHODS: All patients with a diverticular-associated abscess were identified between 2001 and 2012. Individual charts were queried for peri-procedural data and follow-up. The most recent follow-up data were acquired via the electronic medical record or telephone call...
May 30, 2017: International Journal of Colorectal Disease
https://www.readbyqxmd.com/read/28525195/-acute-colonic-diverticulitis-outcome-according-to-general-practice-management-prior-to-referral-and-criteria-predictive-of-complications-a-10-year-experience-in-a-university-hospital
#15
P Youatou, W Ngatchou, G Yondou, F Nde, P Mols, A S Ramadan, M Ngassa
INTRODUCTION: Ambulatory treatment of acute uncomplicated diverticulitis has been shown to be safe and effective by several recent studies. The aim of our study was to analyze the outcome of general practice management concerning the complications, the treatment modalities and the hospitalization duration during the first episode of acute diverticulitis. MATERIEL AND METHODS: A total of 176 medical files of patient presenting between January 2000 and December 2010 at the emergency department with a first episode of acute diverticulitis confirmed by an abdominal CT scan were analyzed...
2017: Revue Médicale de Bruxelles
https://www.readbyqxmd.com/read/28523327/complicated-diverticulitis-in-a-de-novo-kidney-transplanted-patient
#16
Liliana Ana TuŢă, Mădălina Boşoteanu, Eugen Dumitru, Mariana Deacu
Diverticular disease is frequent amongst the elderly and immunosuppressed patients. It mainly presents as sigmoid diverticulitis, but severe complications, like bleedings, infections and colon perforation may occur, frequently due to immunosuppressive therapy. Moreover, antibiotherapy and hemostatics may not efficiently control evolution in such cases. Early diagnose and adequate treatment of colonic diverticulosis complicated with lower gastrointestinal bleeding and diverticulitis in immunocompromised patients...
2017: Romanian Journal of Morphology and Embryology, Revue Roumaine de Morphologie et Embryologie
https://www.readbyqxmd.com/read/28493071/nontraumatic-large-bowel-perforation-spectrum-of-etiologies-and-ct-findings
#17
REVIEW
Kunal Kothari, Barak Friedman, Gregory M Grimaldi, John J Hines
Large bowel perforation is an abdominal emergency that results from a wide range of etiologies. Computed tomography is the most reliable modality in detecting the site of large bowel perforation. The diagnosis is made by identifying direct CT findings such as extraluminal gas or contrast and discontinuity along the bowel wall. Indirect CT findings can help support the diagnosis, and include bowel wall thickening, pericolic fat stranding, abnormal bowel wall enhancement, abscess, and a feculent collection adjacent to the bowel...
May 10, 2017: Abdominal Radiology
https://www.readbyqxmd.com/read/28489013/-incidence-cause-and-treatment-of-colonic-perforations-in-iceland-1998-2007-a-nationwide-study
#18
MULTICENTER STUDY
Kristin Jonsdottir, Elsa B Valsdottir, Shreekrishna Datye, Fritz Berndsen, Pall Helgi Moller
INTRODUCTION: Colon perforation is a serious illness with mortality reported from 0-39%. Surgery used to be the gold standard but treatment has changed as studies have indicated comparable results with less invasive treatment. The aim of this study was to evaluate the incidence of acute colon perforations in Iceland, causes and treatment. MATERIAL AND METHODS: A retrospective, nationwide, multicenter analysis was performed based on ICD-10 codes from databases of the main hospitals in Iceland...
February 2017: Læknablađiđ
https://www.readbyqxmd.com/read/28488205/the-value-of-initial-sonography-compared-to-supplementary-ct-for-diagnosing-right-sided-colonic-diverticulitis
#19
Ju Hwa Min, Hyun Cheol Kim, Sang Won Kim, Dal Mo Yang, Sun Jung Rhee, Jiyoung Oh, Sung Eun Ahn
PURPOSE: The purpose of the study was to assess the value of initial sonography in the diagnosis of right-sided colonic diverticulitis in comparison with supplementary CT. MATERIALS AND METHODS: A total of 183 consecutive adult patients with right lower quadrant pain (73 diverticulitis, and 110 non-diverticulitis) who underwent both initial sonography and subsequent CT within 24 h were enrolled in this study. Two reviewers retrospectively assessed imaging findings of diverticula, colonic wall thickening, inflammatory pericolic fat, and pericolic abscess for each sonography and CT and then classified each case as non-diverticulitis, simple diverticulitis or complicated diverticulitis...
May 9, 2017: Japanese Journal of Radiology
https://www.readbyqxmd.com/read/28466633/the-current-management-of-diverticulosis
#20
Walter Elisei, Giovanni Brandimarte, Antonio Tursi
The incidence of diverticulosis and diverticular disease of the colon, including acute diverticulitis, is increasing worldwide, and becoming a significant burden on national health systems in terms of direct and indirect costs. Thus, significant efforts are now being focused to identify the correct therapeutic approach to treat symptomatic patients and to prevent diverticulitis. Fibre, non- absorbable antibiotics, 5-aminosalicylic acid and probioticsare currently being investigated in this way. Unfortunately, current evidences on the effectiveness of some medical treatment in preventing acute diverticulitis recurrence are still lacking...
May 2, 2017: Minerva Medica
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