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https://www.readbyqxmd.com/read/29197435/gap-analysis-of-older-adults-with-type-2-diabetes-receiving-nonsurgical-periodontal-therapy
#1
REVIEW
Enihomo Obadan-Udoh, Samantha Jordan, Olubukola Mudah, Wenche Borgnakke, Mary Tavares
OBJECTIVE: Twenty percent of the elderly US population is diagnosed with diabetes. The elderly are at a higher risk of developing serious complications from diabetes. Regular professional dental care may help control blood glucose levels and thereby diabetes complications. Since such potential benefits could play a clinically significant role in diabetes management, our aim was to identify and review relevant evidence among the older population. MATERIALS AND METHODS: Electronic databases were searched for periodontal intervention studies using modified search terms from previous systematic reviews...
December 2017: Journal of Evidence-based Dental Practice
https://www.readbyqxmd.com/read/29190775/transcriptome-profiling-analysis-of-senescent-gingival-fibroblasts-in-response-to-fusobacterium-nucleatum-infection
#2
Sun-Hee Ahn, Sung-Min Chun, Chungoo Park, Jong-Hee Lee, Seok-Woo Lee, Tae-Hoon Lee
Periodontal disease is caused by dental plaque biofilms. Fusobacterium nucleatum is an important periodontal pathogen involved in the development of bacterial complexity in dental plaque biofilms. Human gingival fibroblasts (GFs) act as the first line of defense against oral microorganisms and locally orchestrate immune responses by triggering the production of reactive oxygen species and pro-inflammatory cytokines (IL-6 and IL-8). The frequency and severity of periodontal diseases is known to increase in elderly subjects...
2017: PloS One
https://www.readbyqxmd.com/read/29183308/frequency-of-visits-and-examinations-in-the-public-dental-service-in-finland-a-retrospective-analysis-2001-2013
#3
Jari Linden, Kim Josefsson, Eeva Widström
BACKGROUND: This study aimed to investigate longitudinally examination and visiting patterns in the Finnish Public Dental Service (PDS) and to relate these to patients' treatment needs and international recommendations on examination intervals. METHODS: Data on patients and their dental visits in the period 2001-2013 were collected from five municipal PDS-units serving a total population of 320,000 inhabitants and using the same database system. Ethical approval was given by the National Institute for Health and Welfare (THL) and permissions to use local data by the directors of health services in each unit...
November 28, 2017: BMC Oral Health
https://www.readbyqxmd.com/read/29065395/life-threatening-atypical-case-of-acute-generalized-exanthematous-pustulosis
#4
Azadeh Tajmir-Riahi, Petra Wörl, Thomas Harrer, Stefan Schliep, Gerold Schuler, Miklos Simon
Antibiotics are known to cause severe cutaneous adverse reactions, such as the rare acute generalized exanthematous pustulosis (AGEP). Unlike Stevens-Johnson syndrome or toxic epidermal necrolysis, AGEP is rarely life-threatening. Systemic involvement is not typical, and if present usually coincides with a mild elevation of the hepatic enzymes and a decrease in renal function. Hence, AGEP is known to have a good prognosis and to be life-threatening only in elderly patients or patients with chronic diseases...
2017: International Archives of Allergy and Immunology
https://www.readbyqxmd.com/read/29047351/lifestyle-factors-are-significantly-associated-with-the-locomotive-syndrome-a-cross-sectional-study
#5
Manabu Akahane, Shingo Yoshihara, Akie Maeyashiki, Yasuhito Tanaka, Tomoaki Imamura
BACKGROUND: The Japanese Orthopedic Association first proposed the concept of "locomotive syndrome" in 2007. It refers to circumstances in which elderly people need nursing care services or are at high risk of requiring such services within a short time. Recently, the public health burden of providing nursing care for elderly individuals has increased. Therefore, locomotive syndrome, and the means of preventing it, are a major public health focus in Japan. The purpose of this study was to investigate the relationships of lifestyle factors, such as smoking, alcohol consumption, sleep duration, and dental health, with locomotive syndrome...
October 18, 2017: BMC Geriatrics
https://www.readbyqxmd.com/read/29023744/the-relationship-of-oral-health-with-general-health-and-ncds-a-brief-review
#6
Christof Dörfer, Christoph Benz, Jun Aida, Guillaume Campard
Oral health is closely related to systemic health. Periodontitis, a chronic inflammatory disease which is highly prevalent worldwide, interacts with a variety of noncommunicable diseases (NCDs). It is a risk factor in the complex pathogenesis of diabetes mellitus and cardiovascular disease and plays a role in the development of endocarditis and recurrent pneumonia in elderly people. However, the available data may be interpreted in different ways, and more and better-designed studies are still needed to answer relevant questions about the causal role of periodontitis in NCDs...
September 2017: International Dental Journal
https://www.readbyqxmd.com/read/29023740/surveillance-and-monitoring-of-oral-health-in-elderly-people
#7
Hideo Miyazaki, Judith A Jones, Eugenio D Beltrán-Aguilar
Continued ageing of the global population is expected to pose significant challenges to maintaining optimum lifelong health in individuals and populations. Oral health is an essential element of general health and quality of life throughout an individual's life course, yet it is often neglected in integrated approaches to general health promotion. Surveillance and monitoring systems are essential for developing oral health policy and strategy at both national and community levels. As major oral diseases, dental caries and periodontal diseases are core indicators for surveillance at every stage of life...
September 2017: International Dental Journal
https://www.readbyqxmd.com/read/28993578/characterizations-of-oral-microbiota-in-elderly-nursing-home-residents-with-diabetes
#8
Taiji Ogawa, Mariko Honda-Ogawa, Kazunori Ikebe, Yumiko Notomi, Yoshiko Iwamoto, Itsuki Shirobayashi, Seiko Hata, Masahito Kibi, Shizuko Masayasu, Satoshi Sasaki, Shigetada Kawabata, Yoshinobu Maeda
Over 700 bacterial species have been detected in the oral cavity. Several studies have suggested that periodontitis is associated with systemic disorders such as diabetes mellitus, indicating a key role for oral microbiota in human health. However, the relationship between oral microbiota and diabetes has not been well clarified. Therefore, we conducted microbiome analysis of saliva samples obtained from 15 elderly residents (3 with type 2 diabetes mellitus [DM] and 12 without diabetes [non-DM]) at three different nursing homes, as well as 9 young healthy controls (HC)...
October 6, 2017: Journal of Oral Science
https://www.readbyqxmd.com/read/28947687/-gustation-and-dysgeusia
#9
Takashi Sasano
The enjoyment of tastes should be one of the greatest pleasures in life. Without the sense of taste, one cannot enjoy one's food. The result would then be poor appetite, eating less and weight loss. As the elderly population in Japan increases, the number of patients suffering from taste disorder has also increased. While changes in the ability to distinguish tastes are partly associated with advancing age, they occur moreover in response to secondary influences, such as the side effects of drugs, or the effects of some diseases including periodontal disease/oral infections, nervous disorders, nutritional impairment, and endocrine disorders...
2017: Clinical Calcium
https://www.readbyqxmd.com/read/28889220/rapamycin-treatment-attenuates-age-associated-periodontitis-in-mice
#10
Jonathan Y An, Ellen K Quarles, Surapat Mekvanich, Alex Kang, Anthony Liu, Danielle Santos, Richard A Miller, Peter S Rabinovitch, Timothy C Cox, Matt Kaeberlein
Interventions that target biological mechanisms of aging have great potential to enhance quality of life by delaying morbidity and mortality. The FDA-approved drug rapamycin is a compelling candidate for such an intervention. In a previous study, it was reported that 3 months of rapamycin treatment is sufficient to increase life expectancy and remodel the gut microbiome in aged mice. Transient treatment with rapamycin or a rapamycin derivative has also been shown to delay immune stem cell senescence and rejuvenate immune function in aged mice and elderly people...
September 9, 2017: GeroScience
https://www.readbyqxmd.com/read/28881387/effects-of-lactoferrin-and-lactoperoxidase-containing-food-on-the-oral-microbiota-of-older-individuals
#11
Manabu Nakano, Hiroyuki Wakabayashi, Hirosuke Sugahara, Toshitaka Odamaki, Koji Yamauchi, Fumiaki Abe, Jin-Zhong Xiao, Kohji Murakami, Kentaro Ishikawa, Shouji Hironaka
The oral microbiota influences health and disease states. Some gram-negative anaerobic bacteria play important roles in tissue destruction associated with periodontal disease. Lactoferrin (LF) and lactoperoxidase (LPO) are antimicrobial proteins found in saliva; however, their influence on the whole oral microbiota currently remains unknown. In this randomized, double-blinded, placebo-controlled study, the effects of long-term ingestion of LF and LPO-containing tablets on the microbiota of supragingival plaque and tongue coating were assessed...
October 2017: Microbiology and Immunology
https://www.readbyqxmd.com/read/28836290/association-between-dental-visits-for-periodontal-treatment-and-type-2-diabetes-mellitus-in-an-elderly-japanese-cohort
#12
Mizuki Saito, Yoshihiro Shimazaki, Toshiya Nonoyama, Yasushi Tadokoro
AIM: There is an association between type 2 diabetes mellitus (T2DM) and periodontitis. We examined the association between the dental visit status and diabetes status in the Japanese elderly population. MATERIALS AND METHODS: In total, 14,551 participants, aged 75 or 80 years, who underwent systemic health examinations were analysed. Three independent variables of dental visit status were investigated according to dental claims data, including whether dental treatment was received, type of dental treatment (no visit, periodontal treatment, or other dental treatment), and number of days of periodontal treatment (0, 1-4, or ≥5 days)...
August 23, 2017: Journal of Clinical Periodontology
https://www.readbyqxmd.com/read/28803419/specific-periodontopathic-bacterial-infection-affects-hypertension-in-male-cardiovascular-disease-patients
#13
Norio Aoyama, Jun-Ichi Suzuki, Hidetoshi Kumagai, Yuichi Ikeda, Hiroshi Akazawa, Issei Komuro, Masato Minabe, Yuichi Izumi, Mitsuaki Isobe
Hypertension (HT) is a systemic disorder that results in the decline of quality of life and death. While patients with periodontitis are at a high risk of HT, little causal information has been provided to date. To clarify the relationship, periodontopathic bacterial infection in cardiovascular patients with or without HT was evaluated. The subjects were patients with (n = 412) or without (n = 199) HT who attended Tokyo Medical and Dental University hospital. Blood examinations and periodontal measurements were performed...
August 12, 2017: Heart and Vessels
https://www.readbyqxmd.com/read/28728082/oral-infections-comorbidities-and-sensory-evidences-in-elderly-cross-sectional-study
#14
Nathalia Santos Viana Silva, Luciana Alvarenga da Silva, Omar Jaluul, Wilson Jacob-Filho, Silvia Regina Dowgan Tesseroli de Siqueira
BACKGROUND: Oral infections affect the general health and overlap with chronic diseases due to infectious-immune mechanisms. On the other side, sensory abnormalities may be symptoms of this association. OBJECTIVE: To evaluate the prevalence of oral infections, comorbidities, health parameters and sensory abnormalities in elderly patients. METHODS: Thirty (30) elderly with mean age 70.4 yo, distributed according to ages were evaluated with a protocol that included demographics, comorbidities, medications, laboratory tests, blood pressure, heart rate, mini-mental state examination, clinical oral evaluation and systematized sensory testing (gustative, olfactory, thermal, mechanical and pain thresholds)...
July 1, 2017: Archives of Gerontology and Geriatrics
https://www.readbyqxmd.com/read/28598287/association-between-periodontitis-and-amyloid-%C3%AE-peptide-in-elderly-people-with-and-without-cognitive-impairment
#15
José Antonio Gil-Montoya, Rocío Barrios, Soraya Santana, Inés Sanchez-Lara, Cristobal Carnero Pardo, Francisco Fornieles-Rubio, Juan Montes, Carlos Ramírez, Miguel Angel González-Moles, Javier S Burgos
BACKGROUND: Evidence that periodontal disease is a possible risk factor for cognitive impairment may be explained by the inflammatory hypothesis. The aim of this study is to determine whether periodontitis is related to the amyloid β (Aβ) load in blood and the role of any such relationship in the association between Aβ and cognitive impairment. METHODS: A case-control study was performed in elderly people diagnosed with cognitive impairment with or without dementia (cases group) and cognitively healthy elderly people (control group); data were collected on the medical and dental history of participants, and blood samples were drawn to determine Aβ levels using enzyme-linked immunosorbent assay...
October 2017: Journal of Periodontology
https://www.readbyqxmd.com/read/28557399/-the-role-of-free-radical-o%C3%B1-idation-for-patogenesis-of-chronic-generalization-periodontitis-in-elderly-age-patients
#16
Y I Pinelis, M S Malezhik, L P Malezhik
In old aged patients with chronic generalized periodontitis and cardiovascular diseases the level lipoperoxidation increased and antioхidation protection decreased in saliva and blood. After the course of treatment myocardial ischemia and diseases chronic periodontal inflammation the level of lipoperoхidation was changed insignificant accompanied with decreased of TBK-active substance in saliva and blood. Change of nitric oхide after by treatment was depended it initial level before treatment and often had an opposite orientation...
2017: Advances in Gerontology, Uspekhi Gerontologii
https://www.readbyqxmd.com/read/28550864/awareness-of-oral-care-reduces-periodontal-inflammation-in-the-elderly-population-but-using-a-powered-toothbrush-showed-no-added-benefit
#17
Romina Brignardello-Petersen
No abstract text is available yet for this article.
June 2017: Journal of the American Dental Association
https://www.readbyqxmd.com/read/28538512/necrotizing-ulcer-after-bcg-vaccination-in-a-girl-with-leukocyte-adhesion-deficiency-type-1
#18
Hidemitsu Kurosawa, Tomoyuki Mizukami, Hiroyuki Nunoi, Masaya Kato, Yuya Sato, Mayuko Okuya, Keitaro Fukushima, Yoshihiko Katsuyama, Osamu Arisaka
Leukocyte-adhesion deficiency-1 is a recessively inherited disorder associated with recurrent bacterial infections, severe periodontitis, peripheral leukocytosis, and impaired wound healing. We diagnosed moderate-type leukocyte-adhesion deficiency-1 in a 7-year-old girl who developed a necrotizing ulcer after Bacillus Calmette-Guerin vaccination. The patient showed moderate expression of CD18 in neutrophils with a homozygous splice mutation with c.41_c.58+2dup20 of ITGB2 and experienced recurrent severe infections complicated with systemic lupus erythematosus...
May 22, 2017: Journal of Pediatric Hematology/oncology
https://www.readbyqxmd.com/read/28462181/estimation-of-serum-triglycerides-serum-cholesterol-total-protein-igg-levels-in-chronic-periodontitis-affected-elderly-patients-a-cross-sectional-study
#19
A V Saravanan, P L Ravishankar, Pradeep Kumar, K Rajapandian, V Kalaivani, M Prem Blaisie Rajula
AIM: The present study was conducted to evaluate the serum triglycerides, serum cholesterol, total protein, and IgG levels in elderly patients who were affected by periodontal disease. MATERIALS AND METHODS: This study was conducted at the Rajah Muthiah Dental College and Hospital in the periodontics division. The study was conducted for a period of 3 months. This study is a prospective analytical study. Sixty individuals who were systemically healthy in the age group of 50 and above were included in this study...
March 2017: Journal of International Society of Preventive & Community Dentistry
https://www.readbyqxmd.com/read/28433071/association-between-the-eruption-of-the-third-molar-and-caries-and-periodontitis-distal-to-the-second-molars-in-elderly-patients
#20
Yu-Hsiang Chou, Pei-Shan Ho, Kun-Yen Ho, Wen-Chen Wang, Kai-Fang Hu
The objective of this study was to verify whether caries and periodontal diseases, when present on the distal surface of the second molars (M2s), are associated with the eruption of the third molars (M3s). In this split-mouth study, we evaluated 70 elderly patients with unilateral maxillary or mandibular M3s who presented to the outpatient clinics of two hospitals. Patients underwent comprehensive oral examinations and radiographical measurements, and we assessed the outcomes of periodontal disease and caries...
May 2017: Kaohsiung Journal of Medical Sciences
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