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Ali Kermanizadeh, Kim Jantzen, David M Brown, Peter Møller, Steffen Loft
To date, the use and translation of nanomedicine from the laboratory to the clinic has been relatively slow. Among other issues, one of the reasons for this tardiness is the lack of the availability of quick and reliable toxicity tools for the screening of nanomaterials (NMs). In this investigation, we apply a flow cytometry-based method for the detection of nanomaterial-induced oxidative stress by measurement of reactive oxygen species production in specific leukocyte subpopulations in human whole blood. The screening of a panel of relevant nanomedical-associated materials (liposomes, silica, iron oxide and functionalized single-walled carbon nanotubes) demonstrated that only the carbon nanotubes induced oxidative stress in human circulating leukocytes...
January 2018: Basic & Clinical Pharmacology & Toxicology
V P Bingman, S Benvenuti
The importance of atmospheric odors for homing pigeon navigation was tested using birds from a loft located in Savannah, GA, in the southeastern United States. When released from a familiar training site, control pigeons and pigeons given intranasal injections of zinc sulfate to produce anosmia both displayed good homeward orientation and homed quickly. When released from three unfamiliar release sites, in contrast, control birds tended to orient southeast, while zinc sulfate-treated birds were more likely to fly northwest...
October 15, 1996: Journal of Experimental Zoology
C U Nwokolo, J J Payne-James, D B Silk, J J Misiewicz, D E Loft
Thirty two patients (74 (43-93) years; median, (range)) with dysphagia because of inoperable, unresectable or recurrent oesophagogastric carcinoma were treated by ethanol induced tumour necrosis (ETN). Endoscopic injection of absolute alcohol was performed using a variceal injector needle, with 0.5-1 ml aliquots injected retrogradely from distal to proximal tumour margin. Dilatation to 12 mm was used only if the endoscope would not traverse the stricture. In patients with total occlusion, injection into the proximal tumour was followed by a repeat endoscopy 3-7 days later...
March 1994: Gut
K Samsinák, J Chmela, E Vobrázková
The authors describe new cases of human dermatitis caused by Pyemotes herfsi occurring in the food mixing shed for the farrowing house in the piggery at a farm in the destrict of Olomouc, where seven persons handling feedstuff were infected. The disease became manifest as a papular rash, appearing particularly on the back, and all over the body except on the hands and face. When the afflicted person discontinued work in the feed mixing shed, the rash disappeared quickly. The mites were found in the granular dust accumulated in the loft above the food mixing shed...
1979: Folia Parasitologica
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