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Venous incompetence

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https://www.readbyqxmd.com/read/28841090/risk-of-venous-thromboembolism-following-surgical-treatment-of-superficial-venous-incompetence
#1
Tom Barker, Felicity Evison, Ruth Benson, Alok Tiwari
BACKGROUND: The invasive management of varicose veins has a known risk of post-operative deep venous thrombosis and subsequent pulmonary embolism. The aim of this study was to evaluate absolute and relative risk of venous thromboembolism (VTE) following commonly used varicose vein procedures. PATIENTS AND METHODS: A retrospective analysis of secondary data using Hospital Episode Statistics database was performed for all varicose vein procedures performed between 2003 and 2013 and all readmissions for VTE in the same patients within 30 days, 90 days, and one year...
August 25, 2017: VASA. Zeitschrift Für Gefässkrankheiten
https://www.readbyqxmd.com/read/28818233/transcatheter-embolization-of-persistent-embryonic-veins-in%C3%A2-venous-malformation-syndromes
#2
Naiem Nassiri, Dustin Crystal, Lauren A Huntress, Susan Murphy
Persistent embryonic veins represent a major source of venous hypertension and morbidity in venous malformation syndromes, such as Klippel-Trénaunay syndrome and congenital lipomatous overgrowth, vascular malformations, epidermal nevus, and skeletal deformities syndrome. Surgical stripping and phlebectomy are the most commonly reported alternatives to compression therapy for refractory cases. These techniques, although effective in those patients who meet the necessary anatomic criteria, can be associated with bleeding, wound-related complications, and recurrence...
September 2017: Journal of Vascular Surgery. Venous and Lymphatic Disorders
https://www.readbyqxmd.com/read/28818217/thirty-sixth-month-follow-up-of-first-in-human-use-of-cyanoacrylate-adhesive-for-treatment-of-saphenous-vein-incompetence
#3
Jose I Almeida, Julian J Javier, Edward G Mackay, Claudia Bautista, Daniel J Cher, Thomas M Proebstle
OBJECTIVE: The objective of this study was to evaluate the long-term safety and effectiveness of endovenous cyanoacrylate (CA)-based closure of incompetent great saphenous veins. METHODS: This was a prospective, single-arm, single-center feasibility study conducted at the Canela Clinic (La Romana, Dominican Republic) to assess the effectiveness and safety of a CA-based adhesive for great saphenous vein closure at 36 months after treatment. Thirty-eight subjects were treated by injection of small boluses of CA under ultrasound guidance and without the use of perivenous tumescent anesthesia or postprocedure graduated compression stockings...
September 2017: Journal of Vascular Surgery. Venous and Lymphatic Disorders
https://www.readbyqxmd.com/read/28766692/truncal-varicose-vein-diameter-and-patient-reported-outcome-measures
#4
T R A Lane, L Varatharajan, F Fiorentino, A C Shepherd, L Zimmo, M S Gohel, I J Franklin, A H Davies
BACKGROUND: Varicose veins and chronic venous disease are common, and some funding bodies ration treatment based on a minimum diameter of the incompetent truncal vein. This study assessed the effect of maximum vein diameter on clinical status and patient symptoms. METHODS: A prospective observational cohort study of patients presenting with symptomatic varicose veins to a tertiary referral public hospital vascular clinic between January 2011 and July 2012. Patients underwent standardized assessment with venous duplex ultrasonography, and completed questionnaires assessing quality of life (QoL) and symptoms (Aberdeen Varicose Vein Questionnaire, EuroQol Five Domain QoL assessment and EuroQol visual analogue scale)...
August 2, 2017: British Journal of Surgery
https://www.readbyqxmd.com/read/28688874/the-role-of-endothelial-dysfunction-and-inflammation-in-chronic-venous-disease
#5
REVIEW
Ricardo Castro-Ferreira, Rita Cardoso, Adelino Leite-Moreira, Armando Mansilha
Chronic venous disease is a potentially prevalent and debilitating condition affecting millions of individuals, mostly in Western world. Predisposing genetic and environmental factors contribute to its development. However, the main etiology remains to be elucidated. An extensive literature search was conducted in Medline using the following key words algorithm: ("Chronic venous disease" OR "Chronic venous insufficiency" OR "varicose veins") AND ("endothelial dysfunction" OR "inflammation"). Besides being a multifactorial disease, it is now recognized that the hallmark of chronic venous disease pathophysiology likely remains in inflammation, possibly triggered by sustained venous hypertension and valvular incompetence...
July 6, 2017: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/28669458/mid-term-results-of-catheter-directed-foam-sclerotherapy-combined-with-tumescent-local-anaesthesia-for-treatment-of-great-saphenous-vein-incompetence
#6
H Ali, A Elbadawy, M Saleh, O Mahmoud
OBJECTIVES: The purpose of this prospective study was to evaluate the occlusion rate, clinical severity, disease specific health related quality of life (HRQoL), and safety in patients with great saphenous vein (GSV) reflux 3 years after a single treatment session of catheter directed foam sclerotherapy (CDFS) combined with peri-saphenous infiltration of tumescent local anaesthesia (TLA). METHODS: A total of 249 patients with symptomatic unilateral GSV incompetence underwent CDFS combined with TLA and were followed up for 3 years...
June 29, 2017: European Journal of Vascular and Endovascular Surgery
https://www.readbyqxmd.com/read/28669248/m%C3%A4-d-term-results-%C3%A4-n-the-treatment-of-var%C3%A4-cose-ve%C3%A4-ns-w%C3%A4-th-n-butyl-cyanoacr%C3%A4-late
#7
Erdinc Eroglu, Alptekin Yasım, Murat Arı, Hasan Ekerbıcer, Aydemir Kocarslan, Mehmet Kabalcı, Mehmet Acıpayam
Aim To present mid-term results of patients with varicose veins treated with N-butyl cyanoacrylate (VariClose®), a nontumescent endovenous ablation technique. Patients and method Endovenous ablation was performed on 180 patients with saphenous vein incompetence between May and October 2014. One hundred sixty-eight subjects capable of being followed-up for 30 months were included. Patients' pre- and postoperative data were recorded. Results Procedures were performed on the great saphenous vein in 159 patients and on the small saphenous vein in nine patients...
January 1, 2017: Phlebology
https://www.readbyqxmd.com/read/28631699/-lower-extremity-venous-diseases-in-primary-knee-osteoarthritis
#8
O M Lesnyak, E V Zubareva, M G Goncharova, D M Maksimov
AIM: To establish a possible association between knee osteoarthritis (OA) and lower extremity venous diseases ((LEVDs) on the basis of thorough clinical and instrumental studies. SUBJECTS AND METHODS: A case-control study recruiting 40-60-year-old women was conducted. A study group included 85 women with knee OA; a control group consisted of 50 women without this condition. The patients of both groups underwent assessment of complaints and goal-directed objective examination to identify joint diseases and chronic LEVDs, knee X-ray study, and duplex scanning of the lower extremity veins...
2017: Terapevticheskiĭ Arkhiv
https://www.readbyqxmd.com/read/28631145/biaxial-mechanical-properties-of-bovine-jugular-venous-valve-leaflet-tissues
#9
Hsiao-Ying Shadow Huang, Jiaqi Lu
Venous valve incompetence has been implicated in diseases ranging from chronic venous insufficiency (CVI) to intracranial venous hypertension. However, while the mechanical properties of venous valve leaflet tissues are central to CVI biomechanics and mechanobiology, neither stress-strain curves nor tangent moduli have been reported. Here, equibiaxial tensile mechanical tests were conducted to assess the tangent modulus, strength and anisotropy of venous valve leaflet tissues from bovine jugular veins. Valvular tissues were stretched to 60% strain in both the circumferential and radial directions, and leaflet tissue stress-strain curves were generated for proximal and distal valves (i...
June 19, 2017: Biomechanics and Modeling in Mechanobiology
https://www.readbyqxmd.com/read/28623986/double-prepuncture-as-a-valuable-adjunctive-technique-for-complex-endovenous-ablation
#10
Scarlett Hao, Samantha Cox, Thomas S Monahan, Rajabrata Sarkar
OBJECTIVE: The objective of this study was to characterize the technique and to report the results of double prepuncture used during complex radiofrequency ablation (RFA) in cases of treating multiple incompetent veins or encountering focal obstruction to catheter advancement. METHODS: A double prepuncture technique was applied in patients requiring endovascular ablation of multiple veins and patients with great saphenous vein cannulation failure. We treated 13 limbs in 12 patients during a 24-month period with RFA in which the double prepuncture technique was used...
July 2017: Journal of Vascular Surgery. Venous and Lymphatic Disorders
https://www.readbyqxmd.com/read/28623983/clinical-presentation-of-women-with-pelvic-source-varicose-veins-in-the-perineum-as-a-first-step-in-the-development-of-a-disease-specific-patient-assessment-tool
#11
Kathleen Gibson, Renee Minjarez, Brian Ferris, Moni Neradilek, Matthew Wise, Julianne Stoughton, Mark Meissner
OBJECTIVE: Pelvic venous incompetence can cause symptomatic varicose veins in the perineum, buttock, and thigh. Presentation, symptom severity, and response to treatment of pelvic source varicose veins are not well defined. Currently available tools to measure the severity of lower extremity venous disease and its effects on quality of life may be inadequate to assess disease severity in these patients. The purpose of this study was to evaluate the histories, demographics, and clinical presentations of women with pelvic source varicose veins and to compare these data to a population of women with nonpelvic source varicose veins...
July 2017: Journal of Vascular Surgery. Venous and Lymphatic Disorders
https://www.readbyqxmd.com/read/28459144/evaluation-of-the-causes-of-erectile-dysfunction-in-patients-undergoing-penile-doppler-ultrasonography-in-pakistan
#12
Usman Khanzada, Sohail Ahmed Khan, Munawar Hussain, Hatem Adel, Kamran Masood, Syed Omair Adil, Murli Manohar
PURPOSE: In patients with erectile dysfunction, it is important to differentiate psychogenic from organic causes. Penile Doppler ultrasonography is a relatively inexpensive and minimally invasive tool for this purpose. This study was conducted to evaluate the causes of erectile dysfunction in an adult male population, using penile Doppler ultrasonography. MATERIALS AND METHODS: A retrospective study was conducted in a single center. All patients who presented with complaints of erectile dysfunction and underwent penile Doppler ultrasonography between July 2014 and June 2016 were included in this study...
April 2017: World Journal of Men's Health
https://www.readbyqxmd.com/read/28440727/foam-sclerotherapy-of-the-great-saphenous-vein-in-association-with-pre-terminal-saphenous-junction-ligation-division-as-an-office-based-procedure-12-month-results
#13
Moro Leo, Ricci Stefano, Antonelli Incalzi Raffaele
Objective Ultrasound-guided foam sclerotherapy (UGFS) - one of the most frequently recommended methods for treating great saphenous vein incompetence - is easy and inexpensive. However, it achieves a lower occlusion rate compared to endovenous thermal ablation. The application of UGFS to pre-terminal great saphenous vein interruption, eliminating the saphenous stem wash out effect, enhances the short-term occlusion rate. This study explores the results of this technique at 12 months. Method Thirty great saphenous veins (28 patients) with junction incompetence, with calibres >6 mm and >30 cm reflux stem length were submitted to echo-guided pre-terminal great saphenous vein interruption and foam great saphenous vein occlusion...
January 1, 2017: Phlebology
https://www.readbyqxmd.com/read/28413031/matrix-metalloproteinases-in-remodeling-of-lower-extremity-veins-and-chronic-venous-disease
#14
REVIEW
Yunfei Chen, Wei Peng, Joseph D Raffetto, Raouf A Khalil
The veins of the lower extremity are equipped with efficient wall, contractile vascular smooth muscle (VSM), and competent valves in order to withstand the high venous hydrostatic pressure in the lower limb and allow unidirectional movement of deoxygenated blood toward the heart. The vein wall structure and function are in part regulated by matrix metalloproteinases (MMPs). MMPs are zinc-dependent endopeptidases that are secreted as inactive pro-MMPs by different cells in the venous wall including fibroblasts, VSM, and leukocytes...
2017: Progress in Molecular Biology and Translational Science
https://www.readbyqxmd.com/read/28411716/pathophysiology-of-varicose-veins
#15
Benjamin N Jacobs, Elizabeth A Andraska, Andrea T Obi, Thomas W Wakefield
BACKGROUND: Varicose veins, a common problem with effects on quality of life, account for a significant cost burden on the health care system. Despite their prevalence, the pathophysiologic mechanism of varicose veins remains incompletely understood. The fundamental issue is whether venous hypertension and valvular incompetence precede and influence the development of vein wall changes or whether the reverse is true. METHODS: We have reviewed the English-language literature to provide the most current understanding of the hemodynamic and cellular and molecular processes that underlie the development of varicose veins...
May 2017: Journal of Vascular Surgery. Venous and Lymphatic Disorders
https://www.readbyqxmd.com/read/28411711/an-update-on-the-currently-available-nonthermal-ablative-options-in-the-management-of-superficial-venous-disease
#16
REVIEW
Nathan W Kugler, Kellie R Brown
BACKGROUND: Chronic venous insufficiency affects millions of Americans with symptoms spanning a broad range. Saphenous incompetence resulting in chronic reflux is at the root of most disease and is amenable to surgical correction. METHODS: We conducted a systematic review of the literature on nonthermal ablative techniques using a MEDLINE (Ovid) search from January 2000 to August 2016. Only prospective studies and literature review articles in the English language were included for final analysis...
May 2017: Journal of Vascular Surgery. Venous and Lymphatic Disorders
https://www.readbyqxmd.com/read/28411697/veclose-trial-12-month-outcomes-of-cyanoacrylate-closure-versus-radiofrequency-ablation-for-incompetent-great-saphenous-veins
#17
Nick Morrison, Kathleen Gibson, Michael Vasquez, Robert Weiss, Daniel Cher, Monte Madsen, Andrew Jones
OBJECTIVE: Endovenous cyanoacrylate closure (CAC) is a new U.S. Food and Drug Administration-approved therapy for treatment of clinically symptomatic venous reflux in saphenous veins. The device is indicated for the permanent closure of lower extremity superficial truncal veins, such as the great saphenous vein (GSV). Early results from a randomized trial of CAC have been reported previously. Herein we report 1-year outcomes. METHODS: There were 222 subjects with symptomatic GSV incompetence randomly assigned to receive either CAC (n = 108) or radiofrequency ablation (RFA; n = 114)...
May 2017: Journal of Vascular Surgery. Venous and Lymphatic Disorders
https://www.readbyqxmd.com/read/28408089/editor-s-choice-mid-term-outcomes-of-endovenous-laser-ablation-in-patients-with-active-and-healed-venous-ulcers-a-follow-up-study
#18
H Sinabulya, R Östmyren, L Blomgren
OBJECTIVES: The aim of this study was to assess the mid-term ulcer recurrence rate in patients with healed or active venous ulcers treated with endovenous laser ablation (EVLA) for incompetent superficial axial veins and to search for possible risk factors for non-healing and recurrence. METHODS: Consecutive patients treated with EVLA because of a healed or active venous ulcer between 2006 and 2013 were identified in the medical records and quality registry and invited to follow-up, including clinical history, study examination, Duplex ultrasound scanning, ankle brachial pressure, photoplethysmography, venous clinical severity score (VCSS), and health related quality of life (HRQoL) measured with EQ5D...
May 2017: European Journal of Vascular and Endovascular Surgery
https://www.readbyqxmd.com/read/28284885/predictors-of-recanalization-for-incompetent-great-saphenous-veins-treated-with-cyanoacrylate-glue
#19
Yiu Che Chan, Yuk Law, Grace C Cheung, Stephen W Cheng
PURPOSE: To determine predictors of recanalization in patients treated with endovenous cyanoacrylate. METHODS: Follow-up by serial clinical and duplex examinations was performed at 1 week, 1 month, 6 months, 12 months, and 24 months of 108 legs in 55 patients (21 men, median age 65 y) with primary varicose veins treated with endovenous cyanoacrylate. Cox regression analysis was used to examine venous characteristics before the procedure: diameter of great saphenous vein (GSV), treatment length of GSV, presence of incompetent perforators, clinical severity of varicose vein, and experience of operator as predictors of recanalization...
May 2017: Journal of Vascular and Interventional Radiology: JVIR
https://www.readbyqxmd.com/read/28255210/postpartum-varicose-veins-supplementation-with-pycnogenol-or-elastic-compression-a-12-month-follow-up
#20
Gianni Belcaro, Mark Dugall, Roberta Luzzi, Edmondo Ippolito, M Rosaria Cesarone
This open registry aimed to evaluate the clinical evolution of postpartum varicose veins (VVs), in healthy women after the second pregnancy, how these veins regain shape and competence, and possible treatments. The registry included two groups of women: (1) those who used elastic compression stockings, and (2) who used an oral venotonic agent (Pycnogenol, 100 mg/d). A total of 12 evaluation targets were established. Minor symptoms were scored in an analogue scale line. A visual analogue scale line evaluated the overall satisfaction relative to elastic compression or Pycnogenol...
March 2017: International Journal of Angiology: Official Publication of the International College of Angiology, Inc
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