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Rose Mary Ferreira Lisboa da Silva, Carlos Eduardo de Souza Miranda, Maira Tonidandel Barbosa, Maria Aparecida Camargos Bicalho
BACKGROUND: The prevalence of orthostatic hypotension (OH) increases with age and is associated with changes in autonomic regulation of blood pressure (BP) and heart rate (HR). OBJECTIVE: to assess HR and HR variability (HRV) in elderly subjects with OH and determine OH predictors. METHODS: a total of 105 patients aged ≥ 60 years, 39 with OH (case group) and 66 without OH (control group) (age-matched) were studied. Patients underwent clinical assessment, electrocardiogram, biochemistry tests and Holter monitoring for spectral analysis of HRV (Fourier transform) in the supine and orthostatism positions to identify low frequency (LF) and high frequency (HF) components, as well as the LF/HF ratio...
March 19, 2018: Arquivos Brasileiros de Cardiologia
Natalia Lorenzo, Irene Mendez, Mikel Taibo, Gianfranco Martinis, Sara Badia, Guillermo Reyes, Rio Aguilar
BACKGROUND: Atrial fibrillation frequently affects patients with valvular heart disease. Ablation of atrial fibrillation during valvular surgery is an alternative for restoring sinus rhythm. OBJECTIVES: This study aimed to evaluate mid-term results of successful atrial fibrillation surgical ablation during valvular heart disease surgery, to explore left atrium post-ablation mechanics and to identify predictors of recurrence. METHODS: Fifty-three consecutive candidates were included...
March 19, 2018: Arquivos Brasileiros de Cardiologia
Jonathan Lichtenberger, Kathryn M Meurs, Etienne Côté
Cardiac arrhythmias often are transient and might not be detected using conventional electrocardiographic (ECG) techniques. The adhesive patch monitor (APM) is a single-lead, lightweight, up to 14-day continuous ambulatory ECG monitor. This study aimed to prospectively assess its usability in four boxer dogs considered either to be healthy or to have arrhythmogenic right ventricular cardiomyopathy. Optimal recording was obtained by placing the APM on the left side of the animal's thorax, at the fifth intercostal space, slightly dorsal to the costochondral junction, and oriented either vertically or parallel to the long axis of the heart...
March 20, 2018: Journal of the American Animal Hospital Association
Elizabeth Regina Carvalho, Roberto Andrés Navarrete Ampuero, Giovana Laís Ruviaro Tuleski, Aparecido Antonio Camacho, Marlos Gonçalves Sousa
Ventricular arrhythmias (VA) are a recognized concern in dogs with degenerative mitral valve disease (DMVD). The coupling interval (CI) and the prematurity index (PI) have been shown to accurately differentiate between benign and malignant VA in people, where ventricular arrhythmias are known to be associated with an increased risk of development of signs of heart failure or sudden death. In this study, we characterized ventricular arrhythmias in dogs with symptomatic and asymptomatic DMVD. Seventy dogs with naturally-occurring DMVD and ventricular arrhythmias were retrospectively studied...
March 13, 2018: Veterinary Research Communications
Yeonsik Noh, Hugo F Posada-Quintero, Yan Bai, Joseph White, John P Florian, Peter R Brink, Ki H Chon
Prolonged and high pressure diving may lead to various physiological changes including significant alterations of autonomic nervous system (ANS) activity that may be associated with altered physical performance, decompression sickness, or central nervous system oxygen toxicity. Ideally, researchers could elucidate ANS function before, during, and after dives that are most associated with altered function and adverse outcomes. However, we have a limited understanding of the activities of the ANS especially during deeper prolonged SCUBA diving because there has never been a convenient way to collect physiological data during deep dives...
2018: Frontiers in Physiology
Evan D Muse, Nathan E Wineinger, Emily G Spencer, Melissa Peters, Riley Henderson, Yunyue Zhang, Paddy M Barrett, Steven P Rivera, Jay G Wohlgemuth, James J Devlin, Dov Shiffman, Eric J Topol
BACKGROUND: Atrial fibrillation (AF) is the most commonly encountered arrhythmia and is associated with an elevated risk of stroke. Improving the identification of patients with the highest risk for AF to enable appropriate surveillance and treatment, if necessary, is critical to reducing AF-associated morbidity and mortality. Multiple common single nucleotide polymorphisms (SNPs) are unequivocally associated with the lifetime risk of AF. In the current study we aimed to prospectively validate an AF genetic risk score (GRS) in previously undiagnosed patients at risk for AF...
March 2018: PLoS Medicine
Eva A H Lanters, Christophe P Teuwen, Ameeta Yaksh, Charles Kik, Lisette J M E van der Does, Elisabeth M J P Mouws, Paul Knops, Nicole J van Groningen, Thijmen Hokken, Ad J J C Bogers, Natasja M S de Groot
BACKGROUND: Early postoperative atrial fibrillation (EPoAF) is associated with thromboembolic events, prolonged hospitalization, and development of late PoAF (LPoAF). It is, however, unknown if EPoAF can be predicted by intraoperative AF inducibility. The aims of this study are therefore to explore (1) the value of intraoperative inducibility of AF for development of both EPoAF and LPoAF and (2) the predictive value of de novo EPoAF for recurrence of LPoAF. METHODS AND RESULTS: Patients (N=496, 75% male) undergoing cardiothoracic surgery for coronary and/or valvular heart disease were included...
March 10, 2018: Journal of the American Heart Association
Irene A Hurst, Gregory Webster, Kerri Z Machut, Nina Gotteiner, Ahmad Sami Chaouki, Elizabeth N Groothuis, Karna Murthy
OBJECTIVE(S): In well-appearing newborns with suspected cardiac ectopy, we sought to evaluate our practice and test whether initial electrocardiogram (ECG) findings were associated with neonatal arrhythmias (NA). STUDY DESIGN: We identified well-appearing, non-anomalous infants >34 weeks' gestation with suspected ectopy over 3.5 years. NA was defined as ≥10% premature atrial contractions (PAC), ≥5 beats of atrial tachycardia, ≥2% premature ventricular contractions (PVCs), or ≥3 beats of ventricular tachycardia...
March 7, 2018: Journal of Perinatology: Official Journal of the California Perinatal Association
Salma I Patel, Michael J Ackerman, Fadi E Shamoun, Jeffrey B Geske, Steve R Ommen, William T Love, Stephen S Cha, Johan M Bos, Steven J Lester
INTRODUCTION: Risk assessment for sudden cardiac death (SCD) in hypertrophic cardiomyopathy (HCM) remains complex. The goal of this study was to assess electrocardiogram (ECG)-derived risk factors on SCD in a large HCM population Methods: Retrospective review of adults with HCM evaluated at Mayo Clinic, Rochester, MN from 1 December 2002 to 31 December 2012 was performed. Data inclusive of ECG and 24-hour ambulatory Holter monitor were assessed. SCD events were documented by ventricular fibrillation (VF) noted on implantable cardioverter defibrillator (ICD), or appropriate VT or VF-terminating ICD shock...
March 7, 2018: Acta Cardiologica
Emi Yuda, Yoshifumi Moriyama, Toshihiko Mori, Yutaka Yoshida, Makoto Kawahara, Junichiro Hayano
Nocturnal heart rate variability (HRV) is thought to reflect healthy recovery function of the autonomic nervous system. Although exercise is recommended for health promotion, exercise itself decreases HRV. We studied acute effect of daytime exercise on nocturnal HRV in 5 healthy adults (age, 22-40 years; 2 female subjects) without regular exercise habit. Using a treadmill, they performed 30-min walking at 4 km/hr and 30-min running at 9 km/hr from 11 a.m. on different days at an interval of 2 weeks. On these days and a day without exercise (control), Holter electrocardiograms were recorded from 9 a...
February 2018: Journal of Exercise Rehabilitation
Metin Celiker, Yuksel Cicek, Suat Tezi, Abdulkadir Ozgur, Hatice Beyazal Polat, Engin Dursun
BACKGROUND: Nasal septum deformities (NSD) are one of the most common causes of upper airway obstruction. Heart rate variability (HRV) is a physiologic parameter that is affected by the balance between the sympathetic and parasympathetic tonus. OBJECTIVE: The aim of this study was to evaluate the effects of a septoplasty operation on HRV parameters as assessed by 24 hours ambulatory Holter recordings in patients with NSD. METHODS: The prospective study involved 54 consecutive patients (16 women and 38 men) who underwent septoplasty due to a marked C- or S-shaped NSD...
March 2018: Journal of Craniofacial Surgery
Günther Neumayr, Peter Lechleitner
OBJECTIVE: A vacation is considered essential to achieve recovery from the stress of work. Knowledge about the potential health effects of holidays is scarce. The East Tyrolean Health Tourism Study is an open comparative study to investigate the cardiovascular effects of a one- week vacation with different activities on healthy vacationers. METHODS: Fifty-two healthy vacationers spending one week in East Tyrol participated in two types of vacation activities (golf vs...
March 1, 2018: Journal of Sports Medicine and Physical Fitness
Cristina Soguero-Ruiz, Inmaculada Mora-Jiménez, Javier Ramos-López, Teresa Quintanilla Fernández, Antonio García-García, Daniel Díez-Mazuela, Arcadi García-Alberola, José Luis Rojo-Álvarez
Many indices have been proposed for cardiovascular risk stratification from electrocardiogram signal processing, still with limited use in clinical practice. We created a system integrating the clinical definition of cardiac risk subdomains from ECGs and the use of diverse signal processing techniques. Three subdomains were defined from the joint analysis of the technical and clinical viewpoints. One subdomain was devoted to demographic and clinical data. The other two subdomains were intended to obtain widely defined risk indices from ECG monitoring: a simple-domain (heart rate turbulence (HRT)), and a complex-domain (heart rate variability (HRV))...
March 1, 2018: International Journal of Environmental Research and Public Health
Kivanc Yalin, Amr Abdin, Evgeny Lyan, Noureddin Sawan, Spyridon Liosis, Christian Elsner, Alexander Jobs, Ben Brüggemann, Jelena Koester, Ingo Eitel, Charlotte Eitel, Roland Richard Tilz
BACKGROUND: The second-generation cryoballoon (CB) is increasingly used for treatment of persistent atrial fibrillation (AF). Data regarding the clinical outcome and mechanism of arrhythmia recurrence following persistent AF ablation using CB is sparse. In this study, we aimed to assess the efficacy of CB and mechanisms of atrial tachyarrhythmia (ATA) recurrence in patients with persistent AF. METHODS AND RESULTS: A total of 133 patients (66 ± 10 years, 60% male) with symptomatic persistent AF, who were scheduled for PVI using the second-generation CB were enrolled...
February 28, 2018: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
Kang An, Jiaquan Zhu, Nan Ma, Min Tang, Ju Mei
BACKGROUND: Our previous study reported a modified endoscopic procedure for nonvalvular atrial fibrillation (AF) that requires only 3 ports in the left chest wall. HYPOTHESIS: Certain preoperative variables might be predictive risk factors for AF recurrence among patients who underwent this procedure. METHODS: From October 2010 to April 2014, 114 patients with either paroxysmal AF (PAF) or nonparoxysmal AF (non-PAF) underwent the procedure and completed postoperative cardiac-rhythm measurement via electrocardiography and Holter monitoring...
February 26, 2018: Clinical Cardiology
Kenneth Bruun Pedersen, Charlotte Madsen, Niels C F Sandgaard, Axel C P Diederichsen, Søren Bak, Axel Brandes
BACKGROUND: Atrial fibrillation (AF) is a major risk factor of stroke, but the association between AF and transient ischemic attack (TIA) is less clear. Despite this, patients with TIA are included in stroke trials. AIMS: To determine the one-year incidence of AF in TIA patients using an insertable cardiac monitor (ICM); second, to determine factors associated with incident AF in these patients. METHODS: Prospective cohort study of patients with TIA with normal standard ECG and 72h Holter monitoring (HM)...
February 25, 2018: Journal of Cardiovascular Electrophysiology
Taner Kasar, Pelin Ayyildiz, Gulhan Tunca Sahin, Erkut Ozturk, Selman Gokalp, Sertac Haydin, Alper Guzeltas, Yakup Ergul
BACKGROUND: We aimed to evaluate rhythm abnormalities in cases of congenitally corrected transposition of the great arteries (ccTGA) and associated treatment strategies. PATIENTS AND METHODS: This retrospective cohort study included 65 pediatric patients with ccTGA who were admitted to the clinic between 2009 and 2017. The patients were divided into two groups, and surgical data, Holter electrocardiographic (ECG) recordings, ECG recordings, electrophysiological data, and device implantation data on the two groups were compared...
February 24, 2018: Congenital Heart Disease
A V Kuskaeva, S Y Niculina, A A Chernova, N V Aksutina, A P Kuskaev, I I Cherkashina
OBJECTIVE: To study associations of I / D polymorphism of the ACE gene with risk of atrial fibrillation (AF) with the aim of detecting groups of patients prone to development of this disease. MATERIALS AND METHODS: We examined 90 probands with confirmed diagnosis of AF and 144 their I, II, III degrees relatives. These families constituted a core group of our study. The control group comprised 100 relatively healthy people without history of cardiovascular diseases...
February 2018: Kardiologiia
Akinori Sairaku, Yukiko Nakano, Nobuo Shiode, Kazuyoshi Suenari, Nozomu Oda, Koichi Ono, Yasuki Kihara
AIM: The bisoprolol transdermal patch is a newly developed β-blocker designed to deliver its pharmaceutical ingredient through the skin surface. We aimed to compare the bisoprolol transdermal patch and bisoprolol fumarate tablet using the heart rate variability (HRV). METHOD: Eligible hypertensive patients received a 2-week administration with a 2.5 mg bisoprolol fumarate tablet, followed by 24-hour Holter monitoring. The tablet was then switched to a 4 mg bisoprolol transdermal patch, and after 2-weeks of its administration, the Holter monitoring was repeated...
February 21, 2018: Cardiovascular Therapeutics
S R Shunmugam, Conn Sugihara, Nick Freemantle, Patrick Round, Steve Furniss, Neil Sulke
PURPOSE: The ultrarapid delayed rectifier current (IKur ) carried by Kv1.5 channels, which are solely expressed in the atrium, is a potential target for safer treatment of paroxysmal atrial fibrillation (PAF). XEN-D0103 is a nanomolar ion channel blocker that selectively inhibits potassium ion flux through the Kv1.5 ion channel. The efficacy of XEN-D0103 in reducing AF burden was assessed in patients with DDDRp permanent pacemakers (PPMs) and PAF. METHODS: A double-blind, placebo-controlled, cross-over study was performed in patients with PAF and DDDRp PPMs with advanced atrial and ventricular Holters allowing beat-to-beat arrhythmia follow-up...
February 19, 2018: Journal of Interventional Cardiac Electrophysiology: An International Journal of Arrhythmias and Pacing
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