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Pancreatic cystadenocarcinoma

Liljana Spasevska, Vesna Janevska, Vlado Janevski, Biljana Noveska, Julija Zhivadinovik
Pancreas is an extremely rare abdominal localization of the solitary fibrous tumor (SFT). It usually grows asymptomatically for a long time before a diagnosis can be made on the basis of symptoms and/or mechanical complications. Due to the rarity and nonspecific clinical presentation, this entity is diagnostically challenging. We present a 47-year-old man with a history of progressive epigastric pain for the last two weeks, and jaundice, who was admitted to hospital for further investigation. Cystadenocarcinoma was suspected based on the radiologic findings, and a pancreatoduodenectomy was performed...
November 1, 2016: Prilozi (Makedonska Akademija Na Naukite i Umetnostite. Oddelenie za Medicinski Nauki)
Ilias P Doulamis, Konstantinos S Mylonas, Christos E Kalfountzos, Danny Mou, Huzaifa Haj-Ibrahim, Dimitrios Nasioudis
BACKGROUND: Pancreatic mucinous cystadenocarcinoma is a rare malignancy. Our aim was to investigate the demographic, pathological characteristics, treatment modalities and survival of patients with mucinous cystadenocarcinoma via the National Cancer Institute's Surveillance Epidemiology and End Results (SEER) database analysis. MATERIALS AND METHODS: This was a retrospective study of SEER database's records on patients with mucinous cystadenocarcinoma diagnosed from 1988 to 2012...
November 2016: International Journal of Surgery
Masaya Munekage, Takuhiro Kohsaki, Sunao Uemura, Hiroyuki Kitagawa, Tsutomu Namikawa, Kazuhiro Hanazaki
Few reports of mucinous cystic neoplasm (MCN) in association with anaplastic carcinoma exist. The present study reported an unusual case of a 25-year-old female exhibiting large pancreatic MCN with anaplastic carcinoma. Notably, the patient was a Jehovah's Witness and therefore refused any blood transfusions. Preoperative diagnosis was invasive pancreatic MCN measuring 12.5 cm with ascites. Distal pancreatectomy was performed in combination with splenectomy and partial resection of the transverse colon. Intraoperative estimated blood loss was 400 ml, therefore a blood transfusion was not required...
April 2016: Molecular and Clinical Oncology
Zhaoxia Wen, Fengqing Yao, Yuxing Wang
The present study aimed to describe the characteristics of cystic pancreatic tumors using computed tomography (CT) and to evaluate the diagnostic accuracy (DA) of post-imaging three-dimensional (3D) reconstruction. Clinical and imaging data, including multi-slice spiral CT scans, enhanced scans and multi-faceted reconstruction, from 30 patients with pathologically confirmed cystic pancreatic tumors diagnosed at the Linyi People's Hospital between August 2008 and June 2014 were retrospectively analyzed. Following the injection of Ultravist® 300 contrast agent, arterial, portal venous and parenchymal phase scans were obtained at 28, 60 and 150 sec, respectively, and 3D reconstructions of the CT images were generated...
April 2016: Experimental and Therapeutic Medicine
Abhirup Banerjee, Sudeep R Shah, Abhiyutthan Singh, Anand Joshi, Devendra Desai
Cystic lesions of the liver are common and a major proportion is formed by parasitic cysts and simple cysts. Biliary cystic tumors (BCTs), namely biliary cystadenoma (BCA) and biliary cystadenocarcinoma (BCAC), are rare tumors which usually arise from the intrahepatic biliary tree. BCAs have malignant potential and are difficult to differentiate from BCAC pre-operatively on radiological imaging. Here we have presented 4 patients with BCTs and reviewed the literature pertaining to them.The data of four patients with BCA/BCAC diagnosed and treated at our institute were retrieved from our database and records were reviewed for age, sex, history, imaging, surgery, pathology and follow-up...
May 2016: Annals of Hepatology
Nicolas Brandone, Flora Poizat, Jeanne Thomassin-Piana, Olivier Turrini, Cornel Popovici, Benoît Terris
Cystic pancreatic neoplasms concern 1 to 2% of the pancreatic tumours. The serous ones are considered benign tumours but since 1989, several pancreatic serous cystadenocarcinomas (SCAC) cases have been reported. We report the case of a SCAC with a particular pattern. An 80-year-old female patient presented a 4-cm tumour in the neck of the pancreas associated with liver lesions evoking, on imagery exams, focal nodular hyperplasia nests. A cephalic duodenopancreatectomy and a resection of the liver lesions were carried out...
April 2016: Annales de Pathologie
Michelle D Reid, Hye-Jeong Choi, Bahar Memis, Alyssa M Krasinskas, Kee-Taek Jang, Gizem Akkas, Shishir K Maithel, Juan M Sarmiento, David A Kooby, Olca Basturk, Volkan Adsay
The literature on "variants" and "malignant" counterparts of pancreatic serous cystic neoplasms (SCNs) is highly conflicted. Clinicopathologic characteristics of 193 SCNs were investigated, along with a critical literature review. For the macrocystic (oligocystic) variant, in this largest series, a demographic profile in contrast to current literature was elucidated, with 21% frequency, predominance in female individuals (4:1), body/tail location (1.7×), younger age of patients (mean age, 50 y), and frequent radiologic misdiagnosis as other megacystic neoplasms...
December 2015: American Journal of Surgical Pathology
Marcel Cerqueira Cesar Machado, Gilton Marques Fonseca, Luciana Rodrigues de Meirelles, Luiz Tenorio de Brito Siqueira, Betina Katz, José Jukemura
Cystic neoplasms account for approximately 10-20% of all pancreatic cysts and 1% of pancreatic cancers. Serous cystadenomas are considered benign tumors with almost no malignant potential, and thus the management is typically only observation with serial imaging. According to the current World Health Organization classification, cases with distant metastases are defined as serous cystadenocarcinomas. To date, only 17 such cases with concomitant synchronous or metachronous liver metastasis have been described in the literature, and eight of these reports described treatment of secondary liver lesions...
November 2015: Pancreatology: Official Journal of the International Association of Pancreatology (IAP) ... [et Al.]
Xu Che, Zhihui Zhang, Yantao Tian, Jianwei Zhang, Yingtai Chen, Chengfeng Wang
OBJECTIVE: To evaluate the value of intraoperative fine needle aspiration cytology (IFNAC) examination in the diagnosis of pancreatic lesions. METHODS: The clinicopathological data of 491 patients with pancreatic lesions treated in our hospital from May 1998 to June 2013 were retrospectively analyzed. Their clinical features, IFNAC findings, pathological results after IFNAC examination and related complications were summarized. The factors affecting the aspiration biopsy accuracy were analyzed using logistic regression and multi factor analysis...
May 2015: Zhonghua Zhong Liu za Zhi [Chinese Journal of Oncology]
Hong Min Kim, Ji Min Chu, Won Hee Kim, Sung Pyo Hong, Ki Baik Hahm, Kwang Hyun Ko
Secondary achalasia or pseudoachalasia is a rare esophageal motor abnormality, which mimics primary achalasia; it is not easily distinguishable from idiopathic achalasia by manometry, radiological examination, or endoscopy. Although the majority of reported pseudoachalasia cases are associated with neoplasms at or near the esophagogastric (EG) junction, other neoplastic processes or even chronic illnesses such as rheumatoid arthritis can lead to the development of pseudoachalasia, for example, mediastinal masses, gastrointestinal (GI) tumors of the liver and biliary tract, and non-GI malignancies...
July 2015: Clinical Endoscopy
B Jais, V Rebours, G Malleo, R Salvia, M Fontana, L Maggino, C Bassi, R Manfredi, R Moran, A M Lennon, A Zaheer, C Wolfgang, R Hruban, G Marchegiani, C Fernández Del Castillo, W Brugge, Y Ha, M H Kim, D Oh, I Hirai, W Kimura, J Y Jang, S W Kim, W Jung, H Kang, S Y Song, C M Kang, W J Lee, S Crippa, M Falconi, I Gomatos, J Neoptolemos, A C Milanetto, C Sperti, C Ricci, R Casadei, M Bissolati, G Balzano, I Frigerio, R Girelli, M Delhaye, B Bernier, H Wang, K T Jang, D H Song, M T Huggett, K W Oppong, L Pererva, K V Kopchak, M Del Chiaro, R Segersvard, L S Lee, D Conwell, A Osvaldt, V Campos, G Aguero Garcete, B Napoleon, I Matsumoto, M Shinzeki, F Bolado, J M Urman Fernandez, M G Keane, S P Pereira, I Araujo Acuna, E C Vaquero, M R Angiolini, A Zerbi, J Tang, R W Leong, A Faccinetto, G Morana, M C Petrone, P G Arcidiacono, J H Moon, H J Choi, R S Gill, D Pavey, M Ouaïssi, B Sastre, M Spandre, C G De Angelis, M A Rios-Vives, M Concepcion-Martin, T Ikeura, K Okazaki, L Frulloni, O Messina, P Lévy
OBJECTIVES: Serous cystic neoplasm (SCN) is a cystic neoplasm of the pancreas whose natural history is poorly known. The purpose of the study was to attempt to describe the natural history of SCN, including the specific mortality. DESIGN: Retrospective multinational study including SCN diagnosed between 1990 and 2014. RESULTS: 2622 patients were included. Seventy-four per cent were women, and median age at diagnosis was 58 years (16-99)...
February 2016: Gut
Sunu Philip, Armin Kamyab, Michael Jacobs
Hemobilia is an uncommon presentation of biliary tract or pancreatic disease. The investigation and management of this clinical problem is challenging. We report on a case of biliary tract hemorrhage from an otherwise asymptomatic right lobe biliary cystadenocarcinoma and review the literature on this unusual presentation. Hemobilia from primary or secondary liver tumors is not frequently reported in the literature. Hemobilia in this setting is usually observed in association with an obvious liver mass or abnormal liver function tests...
April 2015: International Surgery
Osamu Kainuma, Hiroshi Yamamoto, Akihiro Cho, Hidehito Arimitsu, Hiroo Yanagibashi, Nobuhiro Takiguchi, Yoshihiro Nabeya, Hidetada Kawana
Serous cystic neoplasms (SCN) of the pancreas are typically honeycombed microcystic masses, which are believed to be benign entity. This report describes a case of a 69-year-old man with a rare solid type of serous cystadenocarcinoma of the pancreas with liver metastases. A 6-cm well enhanced pancreatic tumor and multiple liver nodules were depicted with contrast medium on computed tomography scan. Distal pancreatectomy was performed at first operation. The cut surface of the tumor was solid and glossy appearance...
March 2015: Pancreatology: Official Journal of the International Association of Pancreatology (IAP) ... [et Al.]
Zhao Liu, Mu-Chuan Yu, Rui Zhao, Yan-Feng Liu, Jian-Ping Zeng, Xian-Qiang Wang, Jing-Wang Tan
AIM: To evaluate the feasibility, safety, and efficacy of laparoscopic pancreaticoduodenectomy (LPD) using a reverse-"V" approach with four ports. METHODS: This is a retrospective study of selected patients who underwent LPD at our center between April 2011 and April 2012. The following data were collected and reviewed: patient characteristics, tumor histology, surgical outcome, resection margins, morbidity, and mortality. All patients were thoroughly evaluated preoperatively by complete hematologic investigations, triple-phase helical computed tomography, upper gastrointestinal endoscopy, and biopsy of ampullary lesions (when present)...
February 7, 2015: World Journal of Gastroenterology: WJG
Mrinal S Garg, Theresa Schuerle, Yulin Liu, Shyam J Thakkar
CONTEXT: Cystic neoplasms, which are less common forms of exocrine pancreatic neoplasms, consist of mainly intraductal papillary mucinous neoplasms (IPMN) and mucinous cystic neoplasms. Mucinous cystic neoplasms, unlike IPMN, are not associated with ductal growth, are usually multilocular in nature, and have ovarian type stroma. Mucinous cystadenocarcinoma is a type of mucinous cystic neoplasm more commonly found in women. Intraductal oncocytic papillary neoplasms of the pancreas are the least common variant of IPMN...
January 2015: JOP: Journal of the Pancreas
Eleonora Gargaglia, Valentina Totti, Guido Ligabue, Roberta Gelmini
INTRODUCTION: Pancreatic masses causing acute obstructive jaundice still pose diagnostic difficulties and their characterization can often be complex as there is significant overlap in their imaging features. CASE REPORT: We describe a case of Intraductal Papillary Mucinous Tumor (IPMT) presenting with acute obstructive jaundice in a patient with history of recurrent mild pancreatitis. Clinical evaluation, abdominal ultrasonography (US) and CT-scan posed suspicion of adenocarcinoma with cystic degeneration of the pancreatic head or mucinous cystadenocarcinoma; magnetic resonance (MR) with magnetic resonance cholangiopancreatography (MRCP) demonstrated the communication of the mass with the main pancreatic duct, posing differential diagnosis between main-duct-IPMT and mucinous cystadenocarcinoma...
July 2014: Annali Italiani di Chirurgia
Faten Limaiem, Tahar Khalfallah, Leila Ben Farhat, Saâdia Bouraoui, Ahlem Lahmar, Sabeh Mzabi
BACKGROUND: Cystic neoplasms of the pancreas are rare and constitute approximately 0.5% of all pancreatic neoplasms. AIMS: The study was to describe clinicopathological features of pancreatic cystic tumors. PATIENTS AND METHODS: In our retrospective study, we reviewed 10 cases of pancreatic cystic neoplasms that were diagnosed at the pathology department of Mongi Slim hospital over a 14-year period (2000-2013). We adopted the latest World Health Organization (WHO) classification (2010) in grouping all tumors...
August 2014: North American Journal of Medical Sciences
Peng-Fei Qiao, Guang-Ming Niu, Yang Gao
The morbidity of papillary cystadenocarcinoma of the pancreas is extremely low and the condition is rarely first found as spinal metastases, thus it is often misdiagnosed prior to surgery. The present study reports a case of papillary cystadenocarcinoma with thoracolumbar metastases in a 56-year-old male. The first symptom to occur was backache, however, computed tomography revealed no positive findings. The pain became exacerbated and the patient underwent lumbar and thoracic vertebrae magnetic resonance imaging, which identified abnormal signals...
September 2014: Oncology Letters
Safak Ozturk, Mutlu Unver, Burcin Kibar Ozturk, Osman Bozbıyık, Varlık Erol, Eyup Kebabcı, Mustafa Olmez, Nihat Zalluhoglu, Umit Bayol
INTRODUCTION: Metastatic tumors of the pancreas are uncommon and rarely detectable clinically. Metastases to the pancreas are rare. We present a patient with pancreatic metastases from a leiomyosarcoma of the uterus and review the literature about the clinical features of pancreatic metastasis and its surgical management. PRESENTATION OF CASE: A 40-year-old woman, who underwent hysterectomy, left oophorectomy, omentectomy and lymp node dissection for leiomyosarcoma of the uterus...
2014: International Journal of Surgery Case Reports
Baohua Hou, Peng Cui, Zhixiang Jian, Shaojie Li, Wei Chen, Yingliang Ou, Jinrui Ou
OBJECTIVE: To study the application of three-dimensional visualization technology for laparoscopic resection of cystic carcinoma in the pancreatic body and tail. METHODS: Six cases of cystic carcinoma in the pancreatic body and tail treated between Nov, 2009 and Mar, 2011 were retrospectively analyzed. The original image data of 64-slice spiral CT were collected and using adaptive region growing algorithm, the serial CT images were segmented and automatically extracted to obtain the 3-dimensional reconstruction images with customized image manipulation software...
November 2013: Nan Fang Yi Ke da Xue Xue Bao, Journal of Southern Medical University
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