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https://www.readbyqxmd.com/read/28108788/outpatient-application-of-formalin-for-chronic-rectal-bleeding-after-prostate-irradiation-a-quasi-experimental-study
#1
Gustavo Arruda Viani, Aline Sakamoto
PURPOSE: The aim of this quasi-experimental study is to evaluate a novel technique for an outpatient application of formalin for chronic rectal bleeding after prostate irradiation. METHODS: This is a quasi- experimental clinical trial developed between January 2010 and July 2015, including 35 patients with chronic radiation rectitis (CRP) due to a previous prostate radiation course. The study's eligibility was (1) completed external beam radiation therapy for prostate carcinoma >6 months previously, (2) rectal bleeding, defined as a frequency of >1× per week and/or needing of blood transfusions, and (3) diagnosis of chronic proctitis at colonoscopy...
January 20, 2017: International Journal of Colorectal Disease
https://www.readbyqxmd.com/read/28089625/azathioprine-for-refractory-ulcerative-proctitis-a-retrospective-multicenter-study
#2
Anne-Laure Mallet, Guillaume Bouguen, Guillaume Conroy, Xavier Roblin, Jean-Bernard Delobel, Jean-François Bretagne, Laurent Siproudhis, Laurent Peyrin-Biroulet
BACKGROUND: Efficacy of azathioprine (AZA) in refractory ulcerative proctitis (UP) is unknown. METHODS: All patients treated with AZA for refractory UP in three referral centers between 2002 and 2012 were included. "Treatment success" in the long-term was defined as the absence of colectomy during follow-up, no need for anti-TNF during follow-up, no ongoing systemic steroids use, no adverse event leading to AZA withdrawal, and clinically quiescent disease at last follow-up...
December 13, 2016: Digestive and Liver Disease
https://www.readbyqxmd.com/read/28067753/long-term-extent-change-of-pediatric-onset-ulcerative-colitis
#3
Firas Rinawi, Amit Assa, Corina Hartman, Yael Mozer Glassberg, Vered Nachmias Friedler, Yoram Rosenbach, Ari Silbermintz, Noam Zevit, Raanan Shamir
BACKGROUND: Data describing extent change (progression or regression) in pediatric-onset ulcerative colitis (UC) are scarce. GOAL: We aimed to describe extent change in pediatric-onset UC during long-term follow-up and to assess predictors of extent change. STUDY: Medical charts of pediatric-onset UC patients with at least 5-year follow-up were analyzed retrospectively. Disease extent was determined using the Paris classification. It was examined at diagnosis and during follow-up at different time points...
January 6, 2017: Journal of Clinical Gastroenterology
https://www.readbyqxmd.com/read/28034833/hyperbaric-oxygen-treatment-reverses-radiation-induced-pro-fibrotic-and-oxidative-stress-responses-in-a-rat-model
#4
N Oscarsson, L Ny, J Mölne, F Lind, S-E Ricksten, H Seeman-Lodding, D Giglio
PURPOSE: Radiotherapy is effective in the treatment of tumors in the pelvic area but is associated with side effects such as cystitis and proctitis. Hyperbaric Oxygen Therapy (HBOT) has emerged as a treatment modality for radiation-induced side effects. In a rat model for radiation cystitis, we studied the effects of HBOT on oxidative stress and pro-fibrotic factors. MATERIALS AND METHODS: Sedated Sprague-Dawley rats underwent bladder irradiation of 20Gy with and without 20 sessions of HBOT during a fortnight...
December 27, 2016: Free Radical Biology & Medicine
https://www.readbyqxmd.com/read/28025783/idelalisib-induced-colitis-and-skin-eruption-mimicking-graft-versus-host-disease
#5
Muhammad Bader Hammami, Ahmad Al-Taee, Marshall Meeks, Mark Fesler, M Yadira Hurley, Dengfeng Cao, Jin-Ping Lai
INTRODUCTION: Idelalisib is a selective inhibitor of the delta isoform of phosphatidylinositol 3-kinase which was approved by the United States Federal Drug Administration in 2014 for the treatment of relapsed chronic lymphocytic leukemia and indolent non-Hodgkin lymphoma. Drug-induced injury of the gastrointestinal tract is a relatively frequent but usually under-recognized disease entity. CASE PRESENTATION: We report the case of a 56-year-old male with a history of relapsed follicular lymphoma status post allogenic bone marrow transplant who developed severe diarrhea with a skin eruption mimicking graft-versus-host disease (GVHD) 6 months after starting idelalisib...
December 26, 2016: Clinical Journal of Gastroenterology
https://www.readbyqxmd.com/read/28012103/determinants-of-healthcare-utilization-among-veterans-with-inflammatory-bowel-disease
#6
Mimi C Tan, Hashem B El-Serag, Jason K Hou
BACKGROUND: Identifying patient-level and disease-specific predictors of healthcare utilization in inflammatory bowel disease (IBD) may allow targeted interventions to reduce costs and improve outcomes. AIM: To identify demographic and clinical predictors of healthcare utilization among veterans with IBD. METHODS: We conducted a single-center cross-sectional study of veterans with IBD from 1998 to 2010. Demographics and disease characteristics were abstracted by manual chart review...
December 23, 2016: Digestive Diseases and Sciences
https://www.readbyqxmd.com/read/28008411/purulent-proctitis-caused-by-prevotella-bivia-in-a-homosexual-male
#7
Maen Masadeh, Sarah Hossain, Jeffrey Dunkelberg, Henning Gerke
A 32-year-old homosexual male presented with suprapubic pain. Computed tomography showed rectal wall thickening. Flexible sigmoidoscopy showed small pockets of pus that were opened with mucosal biopsies, and additional pus was diffusely expressed from the rectal wall by applying blunt pressure with the biopsy forceps. Cultures from the pus grew Prevotella bivia. Symptoms resolved after treatment with doxycycline and metronidazole. Proctitis due to P. bivia was not previously reported.
August 2016: ACG Case Reports Journal
https://www.readbyqxmd.com/read/27984552/increased-detection-of-pharyngeal-and-rectal-gonorrhea-in-men-who-have-sex-with-men-after-transition-from-culture-to-nucleic-acid-amplification-testing
#8
Vincent J Cornelisse, Eric P F Chow, Sarah Huffam, Christopher K Fairley, Melanie Bissessor, Vesna De Petra, Benjamin P Howden, Ian Denham, Catriona S Bradshaw, Deborah Williamson, Marcus Y Chen
BACKGROUND: This before-and-after study measured the impact of a change in testing methods from culture to nucleic acid amplification testing (NAAT) on the detection of pharyngeal and rectal gonorrhea in men who have sex with men (MSM) on a sexual health service level, including the effect on subgroups anticipated to have higher rates of gonorrhea. METHODS: In March 2015, Melbourne Sexual Health Centre changed its laboratory method for gonococcal testing from culture to NAAT using the Aptima Combo 2 and Aptima GC tests...
December 14, 2016: Sexually Transmitted Diseases
https://www.readbyqxmd.com/read/27920612/long-term-clinical-toxicity-of-radiation-therapy-in-prostate-cancer-patients-with-inflammatory-bowel-disease
#9
Matthew M Gestaut, Gregory P Swanson
AIM: The study's aim was to examine the clinical impact of radiation therapy (RT) on GI toxicity in Inflammatory Bowel Disease (IBD) patients. BACKGROUND: IBD has long been considered a risk factor for increased bowel toxicity from RT; however, minimal evidence exists on patients with prostate cancer (PC) and IBD. MATERIALS AND METHODS: The tumor registry was queried for patients with IBD and PC from the years 1990-2013. A retrospective review was conducted for patients who received RT...
January 2017: Reports of Practical Oncology and Radiotherapy
https://www.readbyqxmd.com/read/27862349/lymphogranuloma-venereum-with-only-proximal-rectal-involvement-mimicking-inflammatory-bowel-disease-a-potential-diagnostic-pitfall
#10
LETTER
F Rob, J Kašpírková, K Jůzlová, M Pešta, J Hercogová
No abstract text is available yet for this article.
November 15, 2016: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/27851416/1781-clostridium-difficile-enteritis-and-proctitis-novel-multimodality-treatment-regimen-post-colectomy
#11
Omar Rahman, Hina Farooq, Salman Bin Mahmood, Muhammad Bilal Khalid, Rajat Kapoor, Matthew Wack
No abstract text is available yet for this article.
December 2016: Critical Care Medicine
https://www.readbyqxmd.com/read/27843448/could-total-colectomy-with-ileorectal-anastomosis-be-an-alternative-to-total-proctocolectomy-with-ileal-pouch-anal-anastomosis-in-selected-ulcerative-colitis-patients
#12
Francesco Tonelli, Carmela Di Martino, Francesco Giudici
Purpose. To evaluate ileorectal anastomosis (IRA) in selected ulcerative colitis patients. Methods. Early and late complications after IRA and IPAA were investigated. Bowel function and quality of life were assessed. Functional and QoL studies were performed as a matched pair analysis, comparing 98 patients who underwent IRA versus 98 patients who underwent IPAA. Results. In IRA group, 2 patients (1.6%) developed anastomotic l dysplasia (HGD) developed in 3 patients dysplasia (HGD) developed in 3 patients eakage, 1 patient (0...
2016: Gastroenterology Research and Practice
https://www.readbyqxmd.com/read/27816539/feasibility-study-of-toxicity-outcomes-using-gec-estro-contouring-guidelines-on-ct-based-instead-of-mri-based-planning-in-locally-advanced-cervical-cancer-patients
#13
Vicky Koh, Bok Ai Choo, Khai Mun Lee, Teng Hwee Tan, Jen Hui Jeffrey Low, Soon Yau Joseph Ng, Arunachalam Ilancheran, Liang Shen, Johann Tang
PURPOSE: To report late rectal and bladder toxicity outcomes of a CT-based image-guided brachytherapy (IGBT) technique for treatment of cervical cancer. METHODS AND MATERIALS: Between 2008 and 2014, 95 women with International Federation of Gynecology and Obstetrics stage IB to IVA cervical carcinoma treated with definitive concurrent cisplatin-based chemotherapy and external beam radiation therapy 50.4 Gy in 28 fractions followed by planned prescription dose of 7 Gy × 4 fractions of high-dose-rate IGBT was retrospectively reviewed...
November 2, 2016: Brachytherapy
https://www.readbyqxmd.com/read/27807581/pouchitis-associated-with-pelvic-radiation-for-prostate-cancer
#14
Geeta Kulkarni, Xiuli Liu, Bo Shen
Radiation therapy is a viable option in managing potentially life-threatening malignancies including prostate cancer. It is known that pelvic radiation can result in injury of the distal large bowel with the development of radiation proctitis. Despite reports from retrospective studies, there is a lack of direct endoscopic and histologic evidence of external pelvic radiation injury to the ileal pouch-anal anastomosis. We present a case of a 68-year-old male with pouchitis resulting from pelvic radiation for prostate cancer...
August 2016: ACG Case Reports Journal
https://www.readbyqxmd.com/read/27803429/severe-proctitis-caused-by-chlamydia-trachomatis-serovars-d
#15
Kazuaki Fukushima, Naoki Yanagisawa
No abstract text is available yet for this article.
2016: Internal Medicine
https://www.readbyqxmd.com/read/27799048/prostate-external-beam-radiotherapy-combined-with-high-dose-rate-brachytherapy-dose-volume-parameters-from-deformably-registered-plans-correlate-with-late-gastrointestinal-complications
#16
Calyn R Moulton, Michael J House, Victoria Lye, Colin I Tang, Michele Krawiec, David J Joseph, James W Denham, Martin A Ebert
BACKGROUND: Derivation of dose-volume correlated with toxicity for multi-modal treatments can be difficult due to the perceived need for voxel-by-voxel dose accumulation. With data available for a single-institution cohort with long follow-up, an investigation was undertaken into rectal dose-volume effects for gastrointestinal toxicities after deformably-registering each phase of a combined external beam radiotherapy (EBRT)/high-dose-rate (HDR) brachytherapy prostate treatment. METHODS: One hundred and eighteen patients received EBRT in 23 fractions of 2 Gy and HDR (TG43 algorithm) in 3 fractions of 6...
October 31, 2016: Radiation Oncology
https://www.readbyqxmd.com/read/27782893/diagnostic-evaluation-of-appendiceal-orifice-inflammation-in-ulcerative-colitis
#17
Da Qin Zhan, Xing Chen, Rong Wang, Jing Zhang, Dan Yu Zhao, Shu Jing Zhang, Zhi Feng Wang, Rui Jun Ma, Bo Hou
BACKGROUND/AIMS: To evaluate the diagnostic significance of appendiceal orifice inflammation (AOI) in ulcerative colitis (UC) patients. MATERIALS AND METHODS: We retrospectively examined data from patients with colitis from May 2010 to January 2014 and assigned them to two groups: UC cases and specific colitis cases. First, we clarified the difference in the AOI+ rate between the two groups. Thereafter, imaging findings of all the patients with colitis were re-examined...
September 2016: Turkish Journal of Gastroenterology: the Official Journal of Turkish Society of Gastroenterology
https://www.readbyqxmd.com/read/27780947/-a-case-of-rectal-syphilis-incidentally-found-at-regular-medical-check-up
#18
Ji Hong You, Ki Won Cho, Yoon Jin Cha, Hyo Jin Park
Syphilis is a rare disease in the rectum. It is difficult to diagnose because the characteristics of the rectal syphilis rectal lesion are highly varied. The endoscopic findings of rectal syphilis are proctitis, ulcers, and masses. If rectal syphilis is suspected to be the cause for rectal lesions, it is important for physicians to consider the sexual history and sexual orientation of the patient. We report a case of incidental rectal syphilis in a 41-year-old man diagnosed during a regular medical check-up...
October 25, 2016: Korean Journal of Gastroenterology, Taehan Sohwagi Hakhoe Chi
https://www.readbyqxmd.com/read/27751605/acute-toxicity-with-intensity-modulated-radiotherapy-versus-3-dimensional-conformal-radiotherapy-during-preoperative-chemoradiation-for-locally-advanced-rectal-cancer
#19
Shu Y Ng, Kathryn L Colborn, Lajhem Cambridge, Carla Hajj, T Jonathan Yang, Abraham J Wu, Karyn A Goodman
BACKGROUND AND PURPOSE: We examined acute toxicity profiles and outcomes among rectal cancer patients treated with pre-operative chemoradiation using intensity modulated radiotherapy (IMRT) or 3-dimensional conformal radiotherapy (3DCRT) to identify predictive clinical factors associated with increased acute toxicity. MATERIAL AND METHODS: We retrospectively reviewed records of 301 consecutive rectal cancer patients treated with pre-operative chemotherapy and radiotherapy (median dose 5000cGy) at our institution between 2007 and 2014...
November 2016: Radiotherapy and Oncology: Journal of the European Society for Therapeutic Radiology and Oncology
https://www.readbyqxmd.com/read/27712891/usefulness-of-posterior-sagittal-anorectoplasty-for-redo-pull-through-in-complicated-and-recurrent-hirschsprung-disease-experience-with-a-single-surgical-group
#20
Song Sun, Gong Chen, Shan Zheng, Kuiran Dong, Xianmin Xiao
AIM: To retrospectively examine 12 patients with Hirschsprung disease (HD) who underwent posterior sagittal anorectoplasty (PSARP) for various complications. METHODS: This study included patients with HD who underwent redo pull-through (PT) via PSARP at our institute between 2005 and 2014. The type of initial procedure, clinical presentations, indications, and functional results were analyzed. Postoperative excretory function was assessed using the Krickenbeck classification...
August 31, 2016: Journal of Pediatric Surgery
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