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https://www.readbyqxmd.com/read/28337229/allergic-enteritis-in-children
#1
REVIEW
Mieczysława Czerwionka-Szaflarska, Ewa Łoś-Rycharska, Julia Gawryjołek
The gastrointestinal form of food allergy is very common in children. The most frequently observed types are allergic proctitis and proctocolitis. In most cases the symptoms subside within the first 2 months of life. The babies seem healthy, and the only abnormality is a small amount of blood in stool. Symptoms can also include small intestine inflammation and colitis. Patients may present with irritability, abdominal pain, flatulence, colic, postprandial vomiting, chronic diarrhoea, and hindered physical development...
2017: Przegla̜d Gastroenterologiczny
https://www.readbyqxmd.com/read/28286194/efficacy-of-rectal-tacrolimus-for-induction-therapy-in-patients-with-resistant-ulcerative-proctitis
#2
Ian C Lawrance, Angela Baird, Daniel Lightower, Graham Radford-Smith, Jane M Andrews, Susan Connor
BACKGROUND: Resistant ulcerative proctitis can be extremely difficult to manage. Topically administered tacrolimus, however, may be effective in difficult-to-treat proctitis. AIMS: This was randomized, double-blind, placebo-controlled induction trial of rectal tacrolimus in patients with active ulcerative colitis. METHODS: Eleven patients received rectal tacrolimus (0.5mg/ml), and 10 placebo, for 8 weeks. The primary endpoint was clinical response by using the Mayo clinic score...
March 7, 2017: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/28274568/differences-in-the-outcomes-and-complications-between-elderly-and-younger-uterine-cervical-cancer-patients-treated-by-definitive-radiotherapy-a-propensity-score-matched-study
#3
Yu-Ming Wang, Chong-Jong Wang, Fu-Min Fang, Hui-Chun Chen, Hsuan-Chih Hsu, Yu-Jie Huang, Chang-Yu Wang, Eng-Yen Huang
PURPOSE: To evaluate the differences in the treatment outcomes and complications between elderly patients and younger patients with uterine cervical cancer (CxCa). METHODS AND MATERIALS: From April 1993 to December 2007, 138 CxCa patients aged ≥75years (Elderly group) and 334 CxCa patients aged <60years (Young group) who underwent definitive radiotherapy/chemoradiotherapy at our institution were reviewed. Two propensity score-matched cohorts of patients were selected from both age groups to evaluate the differences in the outcomes and complications...
March 5, 2017: Gynecologic Oncology
https://www.readbyqxmd.com/read/28245859/californium-252-neutron-brachytherapy-combined-with-external-pelvic-radiotherapy-plus-concurrent-chemotherapy-for-cervical-cancer-a-retrospective-clinical-study
#4
Shen Qian, Ling Ye, Yun-Hong Tian, Li-Gen Wang, Zuo-Ping Huang, Feng Li, Bing Hou, Ni Song, Juan Chen, Ying Liu, Xiao Liu, Tao Zhou
BACKGROUND: Cervical cancer is the sixth most common cancer in Chinese women. A standard treatment modality for cervical cancer is the combination of surgery, chemotherapy, external-beam radiotherapy and intracavitary brachytherapy. The aim of this study was to retrospectively assess the long-term treatment outcomes of patients with cervical cancer who were treated with californium-252 neutron brachytherapy combined with external-beam radiotherapy plus concurrent chemotherapy. METHODS: We retrospectively analyzed the medical records of 150 patients with primary stages IB-IVB cervical cancer who received neutron brachytherapy combined with external-beam radiotherapy concurrently with cisplatin chemotherapy...
February 28, 2017: Chinese Journal of Cancer
https://www.readbyqxmd.com/read/28238954/histologic-normalization-occurs-in-ulcerative-colitis-and-is-associated-with-improved-clinical-outcomes
#5
Britt Christensen, Stephen B Hanauer, Jonathan Erlich, Olufemi Kassim, Peter R Gibson, Jerrold R Turner, John Hart, David T Rubin
BACKGROUND & AIMS: Mucosal healing, determined by histologic analysis, is a potential therapeutic target for patients with ulcerative colitis (UC). However, the histologic features of tissue normalization, as an outcome of treatment, have not been well described. We examined the prevalence and predictive values of normalization of the colonic mucosa, based on histologic analysis (histologic normalization) in patients with UC, and determined its association with risk of clinical relapse, compared to disease quiescence and mucosal healing...
February 23, 2017: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/28221124/two-cases-of-neisseria-meningitidis-proctitis-in-hiv-positive-men-who-have-sex-with-men
#6
José Gutierrez-Fernandez, Verónica Medina, Carmen Hidalgo-Tenorio, Raquel Abad
We report 2 cases from Spain of infectious proctitis caused by Neisseria meningitidis in HIV-positive men who have sex with men. Genetic characterization of the isolates showed that they are unusual strains not found in other more frequent meningococcal locations. This finding suggests an association between specific strains and anogenital tract colonization.
March 2017: Emerging Infectious Diseases
https://www.readbyqxmd.com/read/28196678/co-infection-by-lymphogranuloma-venereum-and-haemophilus-parainfluenzae-during-an-episode-of-proctitis
#7
Antonio Maria Caballero-Mateos, Mercedes López de Hierro-Ruiz, Mario Rodríguez-Domínguez, Juan Carlos Galán-Montemayor, José Gutiérrez-Fernández
No abstract text is available yet for this article.
February 10, 2017: Gastroenterología y Hepatología
https://www.readbyqxmd.com/read/28183394/emergence-of-the-lymphogranuloma-venereum-l2c-genovariant-hungary-2012-to-2016
#8
Fruzsina Petrovay, Eszter Balla, Tímea Erdősi
In eastern Europe, few countries have so far reported laboratory-confirmed cases of lymphogranuloma venereum (LGV). Here we describe 22 LGV cases in men who have sex with men (MSM) detected in Hungary from November 2012 to July 2016. Sequence analyses show that 16 of these 22 cases were affected by the L2c genovariant, with from 2012 to 2014, one LGV L2c case detected per year, followed by seven cases in 2015 and six up to July 2016. Of the 16 total L2c LGV cases, 10 had severe haemorrhagic proctitis. These findings are concerning as cases with this new genovariant among MSM have not been frequently reported in Europe to date...
February 2, 2017: Euro Surveillance: Bulletin Européen sur les Maladies Transmissibles, European Communicable Disease Bulletin
https://www.readbyqxmd.com/read/28174920/op007-a-multi-centre-double-blind-randomised-placebo-controlled-study-of-the-use-of-rectal-tacrolimus-in-the-treatment-of-resistant-ulcerative-proctitis
#9
I C Lawrance, A Baird, D Lightowler, G Radford-Smith, J M Andrews, S Connor
No abstract text is available yet for this article.
February 1, 2017: Journal of Crohn's & Colitis
https://www.readbyqxmd.com/read/28172987/p656-is-there-a-role-for-additional-oral-mesalamine-therapy-in-the-treatment-of-ulcerative-proctitis-with-skip-inflammation
#10
Y S Choi, W J Kim, J K Kim, K-H Song, H-J Jung
No abstract text is available yet for this article.
February 1, 2017: Journal of Crohn's & Colitis
https://www.readbyqxmd.com/read/28151584/can-a-peri-rectal-hydrogel-spaceoar-programme-for-prostate-cancer-intensity-modulated-radiotherapy-be-successfully-implemented-in-a-regional-setting
#11
Bridget L Te Velde, Justin Westhuyzen, Nader Awad, Maree Wood, Thomas P Shakespeare
INTRODUCTION: The aim of this study was to investigate whether the implementation of a hydrogel spacer (SpaceOAR) programme for patients treated with 81 Gy prostate intensity-modulated radiotherapy (IMRT) in a regional setting can reduce rectal doses and toxicity. METHODS: In this retrospective study, 125 patients with localised prostate cancer treated between April 2014 (programme commencement) and June 2015 were compared: 65 with SpaceOAR (inserted by five different urologists) and 60 patients treated over the same time period without SpaceOAR...
February 2, 2017: Journal of Medical Imaging and Radiation Oncology
https://www.readbyqxmd.com/read/28143418/reactivated-cytomegalovirus-proctitis-in-an-immunocompetent-patient-presenting-as-nosocomial-diarrhea-a-case-report-and-literature-review
#12
Chun-Yuan Lee, Yen-Hsu Chen, Po-Liang Lu
BACKGROUND: Reactivated cytomegalovirus (CMV) infection has been known to cause significant morbidity and mortality in immunocompromised patients. However, CMV disease rarely develops in immunocompetent patients, and reported cases often present with a mild, self-limiting course, without severe life-threatening sequelae. While the colon is the most common gastrointestinal site affected by CMV disease in immunocompetent patients, rectal involvement is rarely reported. CMV proctitis can present in two distinct forms, primary and reactivated...
February 1, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/28129973/acute-toxicity-and-its-dosimetric-correlates-for-high-risk-prostate-cancer-treated-with-moderately-hypofractionated-radiotherapy
#13
Moses Arunsingh, Indranil Mallick, Sriram Prasath, B Arun, Sandip Sarkar, Raj Kumar Shrimali, Sanjoy Chatterjee, Rimpa Achari
AIMS: To report the acute toxicity and the dosimetric correlates after moderately hypofractionated radiotherapy for localized prostate cancer. METHODS: A total of 101 patients with localized prostate cancer were treated with image-guided intensity-modulated radiation therapy. Patients were treated to 65Gy/25Fr/5 weeks (n = 18), or 60Gy/20Fr/4 weeks (n = 83). Most (82.2%) had high-risk or pelvic node-positive disease. Acute toxicity was assessed using Radiation Therapy Oncology Group (RTOG) acute morbidity scoring criteria...
April 2017: Medical Dosimetry: Official Journal of the American Association of Medical Dosimetrists
https://www.readbyqxmd.com/read/28115952/salvage-high-dose-rate-brachytherapy-for-histologically-confirmed-macroscopic-local-relapsed-prostate-cancer-after-radical-prostatectomy
#14
David Buchser, Alfonso Gomez-Iturriaga, J Ignacio Rodriguez Melcon, Francisco Casquero, Roberto Llarena, Jon Cacicedo, Pedro Bilbao
PURPOSE: To evaluate the feasibility of the use of real-time magnetic resonance imaging (MRI)-transrectal ultrasound (TRUS) fusion guided high-dose-rate brachytherapy (HDR-BT) +/- external beam radiation therapy (EBRT) in patients with histologically-proven local relapse after radical prostatectomy. MATERIAL AND METHODS: We retrospectively reviewed 13 patients treated with real-time MRI-TRUS fusion HDR-BT for a local relapse of prostate cancer after radical surgery...
December 2016: Journal of Contemporary Brachytherapy
https://www.readbyqxmd.com/read/28108788/outpatient-application-of-formalin-for-chronic-rectal-bleeding-after-prostate-irradiation-a-quasi-experimental-study
#15
Gustavo Arruda Viani, Aline Sakamoto
PURPOSE: The aim of this quasi-experimental study is to evaluate a novel technique for an outpatient application of formalin for chronic rectal bleeding after prostate irradiation. METHODS: This is a quasi- experimental clinical trial developed between January 2010 and July 2015, including 35 patients with chronic radiation rectitis (CRP) due to a previous prostate radiation course. The study's eligibility was (1) completed external beam radiation therapy for prostate carcinoma >6 months previously, (2) rectal bleeding, defined as a frequency of >1× per week and/or needing of blood transfusions, and (3) diagnosis of chronic proctitis at colonoscopy...
January 20, 2017: International Journal of Colorectal Disease
https://www.readbyqxmd.com/read/28089625/azathioprine-for-refractory-ulcerative-proctitis-a-retrospective-multicenter-study
#16
Anne-Laure Mallet, Guillaume Bouguen, Guillaume Conroy, Xavier Roblin, Jean-Bernard Delobel, Jean-François Bretagne, Laurent Siproudhis, Laurent Peyrin-Biroulet
BACKGROUND: Efficacy of azathioprine (AZA) in refractory ulcerative proctitis (UP) is unknown. METHODS: All patients treated with AZA for refractory UP in three referral centers between 2002 and 2012 were included. "Treatment success" in the long-term was defined as the absence of colectomy during follow-up, no need for anti-TNF during follow-up, no ongoing systemic steroids use, no adverse event leading to AZA withdrawal, and clinically quiescent disease at last follow-up...
December 13, 2016: Digestive and Liver Disease
https://www.readbyqxmd.com/read/28067753/long-term-extent-change-of-pediatric-onset-ulcerative-colitis
#17
Firas Rinawi, Amit Assa, Corina Hartman, Yael Mozer Glassberg, Vered Nachmias Friedler, Yoram Rosenbach, Ari Silbermintz, Noam Zevit, Raanan Shamir
BACKGROUND: Data describing extent change (progression or regression) in pediatric-onset ulcerative colitis (UC) are scarce. GOAL: We aimed to describe extent change in pediatric-onset UC during long-term follow-up and to assess predictors of extent change. STUDY: Medical charts of pediatric-onset UC patients with at least 5-year follow-up were analyzed retrospectively. Disease extent was determined using the Paris classification. It was examined at diagnosis and during follow-up at different time points...
January 6, 2017: Journal of Clinical Gastroenterology
https://www.readbyqxmd.com/read/28034833/hyperbaric-oxygen-treatment-reverses-radiation-induced-pro-fibrotic-and-oxidative-stress-responses-in-a-rat-model
#18
N Oscarsson, L Ny, J Mölne, F Lind, S-E Ricksten, H Seeman-Lodding, D Giglio
PURPOSE: Radiotherapy is effective in the treatment of tumors in the pelvic area but is associated with side effects such as cystitis and proctitis. Hyperbaric Oxygen Therapy (HBOT) has emerged as a treatment modality for radiation-induced side effects. In a rat model for radiation cystitis, we studied the effects of HBOT on oxidative stress and pro-fibrotic factors. MATERIALS AND METHODS: Sedated Sprague-Dawley rats underwent bladder irradiation of 20Gy with and without 20 sessions of HBOT during a fortnight...
December 27, 2016: Free Radical Biology & Medicine
https://www.readbyqxmd.com/read/28025783/idelalisib-induced-colitis-and-skin-eruption-mimicking-graft-versus-host-disease
#19
Muhammad Bader Hammami, Ahmad Al-Taee, Marshall Meeks, Mark Fesler, M Yadira Hurley, Dengfeng Cao, Jin-Ping Lai
INTRODUCTION: Idelalisib is a selective inhibitor of the delta isoform of phosphatidylinositol 3-kinase which was approved by the United States Federal Drug Administration in 2014 for the treatment of relapsed chronic lymphocytic leukemia and indolent non-Hodgkin lymphoma. Drug-induced injury of the gastrointestinal tract is a relatively frequent but usually under-recognized disease entity. CASE PRESENTATION: We report the case of a 56-year-old male with a history of relapsed follicular lymphoma status post allogenic bone marrow transplant who developed severe diarrhea with a skin eruption mimicking graft-versus-host disease (GVHD) 6 months after starting idelalisib...
April 2017: Clinical Journal of Gastroenterology
https://www.readbyqxmd.com/read/28012103/determinants-of-healthcare-utilization-among-veterans-with-inflammatory-bowel-disease
#20
Mimi C Tan, Hashem B El-Serag, Jason K Hou
BACKGROUND: Identifying patient-level and disease-specific predictors of healthcare utilization in inflammatory bowel disease (IBD) may allow targeted interventions to reduce costs and improve outcomes. AIM: To identify demographic and clinical predictors of healthcare utilization among veterans with IBD. METHODS: We conducted a single-center cross-sectional study of veterans with IBD from 1998 to 2010. Demographics and disease characteristics were abstracted by manual chart review...
December 23, 2016: Digestive Diseases and Sciences
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