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https://www.readbyqxmd.com/read/28526767/migraine-and-cerebrovascular-atherosclerosis-in-patients-with-ischemic-stroke
#1
Hendrikus J A van Os, Inge A Mulder, Alexander Broersen, Ale Algra, Irene C van der Schaaf, L Jaap Kappelle, Birgitta K Velthuis, Gisela M Terwindt, Wouter J Schonewille, Marieke C Visser, Michel D Ferrari, Marianne A A van Walderveen, Marieke J H Wermer
BACKGROUND AND PURPOSE: Migraine is a well-established risk factor for ischemic stroke, but migraine is also related to other vascular diseases. This study aims to investigate the association between migraine and cerebrovascular atherosclerosis in patients with acute ischemic stroke. METHODS: We retrieved data on patients with ischemic stroke from the DUST (Dutch Acute Stroke Study). Migraine history was assessed with a migraine screener and confirmed by telephone interview based on the ICHD criteria (International Classification of Headache Disorders)...
May 19, 2017: Stroke; a Journal of Cerebral Circulation
https://www.readbyqxmd.com/read/28521349/postoperative-hematoma-requiring-recraniotomy-in-1149-consecutive-patients-with-intracranial-tumors
#2
Teruyoshi Kageji, Shinji Nagahiro, Yoshifumi Mizobuchi, Kohei Nakajima
BACKGROUND: The reported 30-day mortality rate after brain tumor surgery is 2.2% to 2.9%, with a postoperative hematoma (POH) as the most frequent cause of death. OBJECTIVE: To investigate the risk factors for a POH requiring a recraniotomy after brain tumor surgery in a large, contemporary, single-institution consecutive series. METHODS: We included 1149 patients who underwent surgery for intracranial tumors at the Tokushima University Hospital from 1997 to 2014...
June 1, 2017: Operative Neurosurgery (Hagerstown, Md.)
https://www.readbyqxmd.com/read/28514899/clinical-positioning-accuracy-for-multisession-stereotactic-radiotherapy-with-the-gamma-knife-perfexion
#3
Wade P Smith, Lori A Young, Mark H Phillips, Michael Cheung, Lia M Halasz, Jason K Rockhill
Multisession stereotactic radiation therapy is increasingly being seen as a preferred option for intracranial diseases in close proximity to critical structures and for larger target volumes. The objective of this study is to investigate the reproducibility of the Extend system from Elekta. A retrospective review was conducted for all patients treated with multisession Gamma Knife between July 2010 and June 2015, including both malignant and benign lesions. Eighty-four patients were treated in this 5-year span...
January 1, 2017: Technology in Cancer Research & Treatment
https://www.readbyqxmd.com/read/28512057/normative-morphometric-data-for-cerebral-cortical-areas-over-the-lifetime-of-the-adult-human-brain
#4
Olivier Potvin, Louis Dieumegarde, Simon Duchesne
Proper normative data of anatomical measurements of cortical regions, allowing to quantify brain abnormalities, are lacking. We developed norms for regional cortical surface areas, thicknesses, and volumes based on cross-sectional MRI scans from 2713 healthy individuals aged 18 to 94 years using 23 samples provided by 21 independent research groups. The segmentation was conducted using FreeSurfer, a widely used and freely available automated segmentation software. Models predicting regional cortical estimates of each hemisphere were produced using age, sex, estimated total intracranial volume (eTIV), scanner manufacturer, magnetic field strength, and interactions as predictors...
May 13, 2017: NeuroImage
https://www.readbyqxmd.com/read/28509324/three-dimensional-neurosonography-a-novel-field-in-fetal-medicine
#5
Michał Lipa, Ritsuko Kimata Pooh, Mirosław Wielgoś
Neurosonography is a promising technique for prenatal diagnosis, combining features of ultrasound imaging with fetal neurology. The brain is a three-dimensional structure, therefore observing brain structure in the three basic planes (sagittal, coronal and axial) is mandatory. The anterior fontanelle and sagittal suture may serve as acoustic ultrasound windows in the transvaginal brain scan, allowing to obtain high-resolution neuroimages of the intracranial structures. Furthermore, three-dimensional (3D) ultrasound combined with the transvaginal brain approach provides detailed and sophisticated neuroimages...
2017: Ginekologia Polska
https://www.readbyqxmd.com/read/28505996/depression-one-year-after-hemorrhagic-stroke-is-associated-with-late-worsening-of%C3%A2-outcomes
#6
Sara Stern-Nezer, Irina Eyngorn, Michael Mlynash, Ryan W Snider, Chitra Venkatsubramanian, Christine A C Wijman, Marion S Buckwalter
BACKGROUND: Poststroke depression is the most common psychiatric sequelae of stroke, and it's independently associated with increased morbidity and mortality. Few studies have examined depression after intracranial hemorrhage (ICH). OBJECTIVE: To investigate the relationship between depression, ICH and outcomes. METHODS: A substudy of the prospective Diagnostic Accuracy of MRI in Spontaneous Intracerebral Hemorrhage (DASH) study, we included 89 subjects assessed for depression 1 year after hemorrhage...
May 11, 2017: NeuroRehabilitation
https://www.readbyqxmd.com/read/28505972/alzheimer-s-disease-associated-cerebrospinal-fluid-csf-biomarkers-do-not-correlate-with-csf-volumes-or-csf-production-rate
#7
Mikael Edsbagge, Ulf Andreasson, Khalid Ambarki, Carsten Wikkelsø, Anders Eklund, Kaj Blennow, Henrik Zetterberg, Mats Tullberg
BACKGROUND: Neuropathologically, Alzheimer's disease (AD) is characterized by accumulation of a 42 amino acid peptide called amyloid-β (Aβ42) in extracellular senile plaques together with intraneuronal inclusions of hyperphosphorylated tau protein in neurofibrillary tangles and neuronal degeneration. These changes are reflected in the cerebrospinal fluid (CSF), the volumes and production rates of which vary considerably between individuals, by reduced concentration of Aβ42, increased concentration of phosphorylated tau (P-tau) protein, and increased concentration of total tau (T-tau) protein, respectively...
May 8, 2017: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/28500560/radiation-necrosis-with-stereotactic-radiosurgery-combined-with-ctla-4-blockade-and-pd-1-inhibition-for-treatment-of-intracranial-disease-in-metastatic-melanoma
#8
Penny Fang, Wen Jiang, Pamela Allen, Isabella Glitza, Nandita Guha, Patrick Hwu, Amol Ghia, Jack Phan, Anita Mahajan, Hussein Tawbi, Jing Li
Immune checkpoint inhibitors have demonstrated remarkable benefits in cancer patients. However, concern regarding toxicity in the setting of stereotactic radiosurgery (SRS) is often raised. In this study, we characterize radiation necrosis (RN) following immunotherapy and SRS. Melanoma patients treated with SRS and anti-CTLA-4 and/or anti-PD-1 at our institution from January 2006 to December 2015 were retrospectively reviewed. Overall survival (OS) and time to RN were assessed using Kaplan-Meier analysis. Logistic regression and Cox proportional hazards analyses were performed to identify predictors of radiation necrosis-free survival (RNFS) and RN risk...
May 12, 2017: Journal of Neuro-oncology
https://www.readbyqxmd.com/read/28499454/risk-for-intracranial-pressure-increase-related-to-enclosed-air-in-post-craniotomy-patients-during-air-ambulance-transport-a-retrospective-cohort-study-with-simulation
#9
Helge Brändström, Anna Sundelin, Daniela Hoseason, Nina Sundström, Richard Birgander, Göran Johansson, Ola Winsö, Lars-Owe Koskinen, Michael Haney
BACKGROUND: Post-craniotomy intracranial air can be present in patients scheduled for air ambulance transport to their home hospital. We aimed to assess risk for in-flight intracranial pressure (ICP) increases related to observed intracranial air volumes, hypothetical sea level pre-transport ICP, and different potential flight levels and cabin pressures. METHODS: A cohort of consecutive subdural hematoma evacuation patients from one University Medical Centre was assessed with post-operative intracranial air volume measurements by computed tomography...
May 12, 2017: Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine
https://www.readbyqxmd.com/read/28498930/risk-factors-for-intracranial-aneurysm-rupture-a-systematic-review
#10
Rachel Kleinloog, Nikki de Mul, Bon H Verweij, Jan Andries Post, Gabriel J E Rinkel, Ynte M Ruigrok
BACKGROUND: Intracranial aneurysm rupture prediction is poor, with only a few risk factors for rupture identified and used in clinical practice. OBJECTIVE: To provide an overview of all the risk factors (including genetic, molecular, morphological, and hemodynamic factors) that have potential for use in clinical practice. METHODS: We systematically searched PubMed and EMBASE and focused on factors that can be easily assessed in clinical practice, might be used for rupture prediction in clinical practice, and/or are potential targets for further research...
May 11, 2017: Neurosurgery
https://www.readbyqxmd.com/read/28495842/the-impact-of-ocular-hemodynamics-and-intracranial-pressure-on-intraocular-pressure-during-acute-gravitational-changes
#11
Emily S Nelson, Lealem Mulugeta, Andrew Feola, Julia Raykin, Jerry G Myers, Brian C Samuels, C Ross Ethier
Exposure to microgravity causes a bulk fluid shift toward the head, with concomitant changes in blood volume/pressure, intraocular pressure (IOP), and intracranial pressure (ICP). These and other factors are thought to contribute to Visual Impairment and Intracranial Pressure syndrome, a significant health concern for astronauts, characterized by degradation of visual function and ocular anatomical changes. Here we describe a lumped-parameter numerical model to simulate volume/pressure alterations in the eye during gravitational changes...
May 11, 2017: Journal of Applied Physiology
https://www.readbyqxmd.com/read/28495425/volume-staged-stereotactic-radiosurgery-for-large-intracranial-arteriovenous-malformations
#12
Adeel Ilyas, Dale Ding, H Robert Hixson, Zhiyuan Xu, Robert M Starke, Jason P Sheehan
Stereotactic radiosurgery (SRS) is an effective treatment option for intracranial arteriovenous malformations (AVM). However, the treatment of large AVMs (nidus volume ≥12cm(3)) with single-session SRS alone yields generally poor outcomes. Volume-staged SRS (VS-SRS) is a therapeutic strategy for large AVMs which seeks to avoid the disadvantages of single-session SRS, but reports regarding its efficacy remain limited. The aim of this retrospective cohort study is to assess the outcomes of VS-SRS for large AVMs...
May 8, 2017: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/28492874/peripapillary-retinal-pigment-epithelium-layer-shape-changes-from-acetazolamide-treatment-in-the-idiopathic-intracranial-hypertension-treatment-trial
#13
Jui-Kai Wang, Randy H Kardon, Johannes Ledolter, Patrick A Sibony, Mark J Kupersmith, Mona K Garvin
Purpose: Recent studies indicate that the amount of deformation of the peripapillary retinal pigment epithelium and Bruch's membrane (pRPE/BM) toward or away from the vitreous may reflect acute changes in cerebrospinal fluid pressure. The study purpose is to determine if changes in optic-nerve-head (ONH) shape reflect a treatment effect (acetazolamide/placebo + weight management) using the optical coherence tomography (OCT) substudy of the Idiopathic Intracranial Hypertension Treatment Trial (IIHTT) at baseline, 3, and 6 months...
May 1, 2017: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/28491494/the-relationship-between-morphological-lesion-magnetic-source-imaging-and-intracranial-stereo-electroencephalography-in-focal-cortical-dysplasia
#14
Romain Bouet, François Mauguière, Sébastien Daligault, Jean Isnard, Marc Guenot, Olivier Bertrand, Julien Jung
Magnetoencephalography (MEG) is a useful non-invasive technique for presurgical evaluation of focal cortical dysplasia patients. We aimed at clarifying the precise spatial relationship between the spiking volume determined with MEG, the seizure onset zone and the lesional volume in patients with focal cortical dysplasia. We studied the spatial relationships between the MEG spiking volume determined with a recent analysis pipeline, the seizure-onset zone location determined with a quantitative index calculated from intracranial EEG signals ('Epileptogenicity Index') and the lesional volume delineated on brain MRI in 11 patients with Focal Cortical Dysplasia explored with Stereo-electroencephalography (SEEG)...
2017: NeuroImage: Clinical
https://www.readbyqxmd.com/read/28490201/a-comparison-of-haemodynamics-between-subcranial-intracranial-bypass-and-the-traditional-extracranial-intracranial-bypass
#15
Zaitao Yu, Yang Yang, Xiang'en Shi, Hai Qian, Fangjun Liu
BACKGROUND: Ischemic cerebrovascular diseases are traditionally treated using an extracranial-intracranial (EC-IC) bypass. The use of the internal maxillary artery (IMA) in the subcranial-intracranial (SC-IC) bypass was recently described as an alternative treatment. However, the haemodynamics of this new approach have not been defined. METHODS: The haemodynamic parameters (flow volume [FV], internal diameter [ID], time-averaged mean velocity [TAM], pulsatility index [PI] and resistance index [RI]) of the IMA-radial artery graft (RAG)-middle cerebral artery (MCA) (n = 12) bypass and superficial temporal artery (STA)-MCA bypass (n = 18) were measured using intraoperative duplex ultrasonography and compared...
May 11, 2017: British Journal of Neurosurgery
https://www.readbyqxmd.com/read/28488070/cerebral-aneurysm-neck-diameter-is-an-independent-predictor-of-progressive-occlusion-after-stent-assisted-coiling
#16
Masahito Nakazaki, Tadashi Nonaka, Tatsufumi Nomura, Toshiyuki Onda, Yasuyuki Yonemasu, Akira Takahashi, Yuji Hashimoto, Osamu Honda, Shinichi Oka, Masanori Sasaki, Masahiko Daibo, Osamu Honmou
BACKGROUND: Some intracranial aneurysms treated by stent-assisted coiling (SAC) with incomplete occlusion undergo progressive occlusion (PO) during follow-up period. We analyzed the predictors for the occurrence of PO. METHODS: Among 74 cerebral aneurysms treated by SAC using the Enterprise or Neuroform stents from 2010 to 2015, we included 43 aneurysms with occlusion grade of neck remnant (NR, n = 36) or residual aneurysm (RA, n = 7) at the post-procedure. We defined PO as improvement in occlusion grade from RA to NR, or from NR or RA to complete occlusion on angiographic follow-up imaging at 6 months after the procedure...
May 9, 2017: Acta Neurochirurgica
https://www.readbyqxmd.com/read/28486629/effect-of-caudal-block-using-different-volumes-of-local-anaesthetic-on-optic-nerve-sheath-diameter-in-children-a-prospective-randomized-trial
#17
B Lee, B-N Koo, Y S Choi, H K Kil, M-S Kim, J H Lee
Background: Caudal block is commonly administered for postoperative analgesia in children. Although caudal block with 1.5 ml kg -1 local anaesthetic has been reported to reduce cerebral oxygenation in infants, the effect of caudal block on intracranial pressure (ICP) in children has not been well investigated. Optic nerve sheath diameter (ONSD) correlates with degree of ICP. This study aimed to estimate the effects of caudal block on ICP according to volume of local anaesthetic using ultrasonographic measurement of ONSD in children...
May 1, 2017: British Journal of Anaesthesia
https://www.readbyqxmd.com/read/28484524/vertex-epidural-hematoma-an-analysis-of-a-large-series
#18
Vengalathur Ganesan Ramesh, Marappan Kodeeswaran, Kunjithapatham Deiveegan, Venkataraman Sundar, Kuchalambal Sriram
CONTEXT: Vertex epidural hematoma (VEDH) is uncommon. A high index of suspicion is required to suspect and diagnose this condition, and the surgical management is a challenge to neurosurgeons. There are only isolated case reports or small series of VEDH in the literature. AIMS: We have tried to analyze a large series of VEDH seen in our institute. SETTINGS AND DESIGN: Retrospective observational study. SUBJECTS AND METHODS: This is an analysis of case records of patients with VEDH during 17 years period from 1995 to 2012...
April 2017: Asian Journal of Neurosurgery
https://www.readbyqxmd.com/read/28482185/effect-of-exposure-to-polycyclic-aromatic-hydrocarbons-on-basal-ganglia-and-attention-deficit-hyperactivity-disorder-symptoms-in-primary-school-children
#19
Marion Mortamais, Jesus Pujol, Barend L van Drooge, Didac Macià, Gerard Martínez-Vilavella, Christelle Reynes, Robert Sabatier, Ioar Rivas, Joan Grimalt, Joan Forns, Mar Alvarez-Pedrerol, Xavier Querol, Jordi Sunyer
BACKGROUND: Polycyclic aromatic hydrocarbons (PAHs) have been proposed as environmental risk factors for attention deficit hyperactivity disorder (ADHD). The effects of these pollutants on brain structures potentially involved in the pathophysiology of ADHD are unknown. OBJECTIVE: The aim of this study was to investigate the effects of PAHs on basal ganglia volumes and ADHD symptoms in school children. METHODS: We conducted an imaging study in 242 children aged 8-12years, recruited through a set of representative schools of the city of Barcelona, Spain...
May 5, 2017: Environment International
https://www.readbyqxmd.com/read/28479524/efficacy-of-arachnoid-plasty-on-chronic-subdural-hematoma-following-surgical-clipping-of-unruptured-intracranial-aneurysms
#20
Jae-Hyun Kim, Chang-Young Lee, Chang-Hyun Kim
BACKGROUND: We aimed to elucidate the effects of arachnoid plasty (ARP) on chronic subdural hematoma (CSDH) occurrence following clipping surgery. METHODS: In total 217 patients (ARP, n = 97; non-ARP, n = 120) who had undergone unruptured intracranial aneurysm (UIA) surgical clipping via the pterional approach were retrospectively assessed. Predisposing factors for CSDH development following the surgery were investigated. Thickness and volume of the subdural fluid collection (SDFC) were measured to determine whether ARP affects postoperative SDFC...
May 4, 2017: World Neurosurgery
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