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Intracranial volume

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https://www.readbyqxmd.com/read/29454505/current-management-of-intracranial-germ-cell-tumours
#1
A Bowzyk Al-Naeeb, M Murray, G Horan, F Harris, R-D Kortmann, J Nicholson, T Ajithkumar
Intracranial germ cell tumours (icGCTs) are uncommon tumours occurring in children and young adults. They are usually segregated into germinomas and non-germinomatous tumours (NGGCTs) in most classifications. Germinomas are highly curable tumours with multimodality treatment, but NGGCTs are associated with poorer survival outcomes. There are some differences in the approach to the management of icGCTs globally. Current research generally focuses on reducing treatment intensity, particularly the dose and volume of radiotherapy, in order to minimise the risks of late sequelae while maintaining high cure rates in icGCTs...
February 14, 2018: Clinical Oncology: a Journal of the Royal College of Radiologists
https://www.readbyqxmd.com/read/29452862/protective-effect-of-human-leukocyte-antigen-hla-allele-drb1-13-02-on-age-related-brain-gray-matter-volume-reduction-in-healthy-women
#2
Lisa M James, Peka Christova, Scott M Lewis, Brian E Engdahl, Angeliki Georgopoulos, Apostolos P Georgopoulos
BACKGROUND: Reduction of brain volume (brain atrophy) during healthy brain aging is well documented and dependent on genetic, lifestyle and environmental factors. Here we investigated the possible dependence of brain gray matter volume reduction in the absence of the Human Leukocyte Antigen (HLA) allele DRB1*13:02 which prevents brain atrophy in Gulf War Illness (James et al., 2017). METHODS: Seventy-one cognitively healthy women (32-69years old) underwent a structural Magnetic Resonance Imaging (sMRI) scan to measure the volumes of total gray matter, cerebrocortical gray matter, and subcortical gray matter...
February 8, 2018: EBioMedicine
https://www.readbyqxmd.com/read/29445633/the-effect-of-intensive-statin-therapy-on-symptomatic-intracranial-arterial-stenosis
#3
Peiyang Zhou, Zhihua Cao, Pu Wang, Guangzhi Liu, Xuan Yao, Puqing Wang, Guang Li, Guibin Zhang, Ping Gao
Background: The aim of this study was to observe the effect of intensive statin therapy on symptomatic intracranial arterial stenosis. Methods: overall, 120 patients with symptomatic intracranial arterial stenosis were admitted to the Xiangyang No.1 People's Hospital, Hubei University of Medicine, Xiangyang, China from January 2010 to May 2013. They were randomly divided into three groups and were given different doses of atorvastatin orally for 1 year or more, and followed up for 12 months...
February 2018: Iranian Journal of Public Health
https://www.readbyqxmd.com/read/29445328/hippocampal-atrophy-following-subarachnoid-hemorrhage-correlates-with-disruption-of-astrocyte-morphology-and-capillary-coverage-by-aqp4
#4
Maryam Anzabi, Maryam Ardalan, Nina K Iversen, Ali H Rafati, Brian Hansen, Leif Østergaard
Despite successful management of ruptured intracranial aneurysm following subarachnoid hemorrhage (SAH), delayed cerebral ischemia (DCI) remains the main cause of high mortality and morbidity in patients who survive the initial bleeding. Astrocytes play a key role in neurovascular coupling. Therefore, changes in the neurovascular unit including astrocytes following SAH may contribute to the development of DCI and long-term complications. In this study, we characterized morphological changes in hippocampal astrocytes following experimental SAH, with special emphasis on glia-vascular cross-talk and hippocampal volume changes...
2018: Frontiers in Cellular Neuroscience
https://www.readbyqxmd.com/read/29439328/impact-of-total-knee-arthroplasty-with-general-anesthesia-on-brain-networks-cognitive-efficiency-and-ventricular-volume-predict-functional-connectivity-decline-in-older-adults
#5
Haiqing Huang, Jared Tanner, Hari Parvataneni, Mark Rice, Ann Horgas, Mingzhou Ding, Catherine Price
 Using resting state functional magnetic resonance imaging (RS-fMRI), we explored: 1) pre- to post-operative changes in functional connectivity in default mode, salience, and central executive networks after total knee arthroplasty (TKA) with general anesthesia, and 2) the contribution of cognitive/brain reserve metrics these resting state functional declines. Individuals age 60 and older electing unilateral total knee arthroplasty (TKA; n = 48) and non-surgery peers with osteoarthritis (n = 45) completed baseline cognitive testing and baseline and post-surgery (post-baseline, 48-h post-surgery) brain MRI...
2018: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/29437511/computer-simulation-and-optimization-of-cranial-vault-distraction
#6
Michael J Foley, Patrick S Cottler, Silvia S Blemker, Arlen D Denny, Jonathan S Black
OBJECTIVE: The objective of this study was to validate the proof of concept of a computer-simulated cranial distraction, demonstrating accurate shape and end volume. DESIGN: Detailed modeling was performed on pre- and postoperative computed tomographic (CT) scans to generate accurate measurements of intracranial volume. Additionally, digital distraction simulations were performed on the preoperative scan and the resultant intracranial volume and shape were evaluated...
March 2018: Cleft Palate-craniofacial Journal
https://www.readbyqxmd.com/read/29427378/dural-recurrence-among-esthesioneuroblastoma-patients-presenting-with-intracranial-extension
#7
Yao Yu, Ivan H El-Sayed, Michael W McDermott, Philip V Theodosopoulos, Annemieke van Zante, Norbert Kased, Christine M Glastonbury, Adam A Garsa, Sue S Yom
OBJECTIVE: To quantify the rate of late intracranial recurrences among esthesioneuroblastoma patients treated with surgical resection and postoperative radiation. STUDY DESIGN: Retrospective review. METHODS: All patients receiving definitive-intent therapy for esthesioneuroblastoma between March 1995 and September 2015 were reviewed. Presenting disease extent was categorized based on radiologic, operative, and pathologic findings. Between-group survival differences were assessed using Kaplan-Meier method and log-rank test...
February 10, 2018: Laryngoscope
https://www.readbyqxmd.com/read/29426053/-renal-replacement-therapy-in-acute-kidney-injury-indication-and-implementation
#8
Mira Küllmar, Alexander Zarbock
Acute kidney injury (AKI) is a common complication in critically ill patients and is associated with a worse short- and long-term outcome. The KDIGO (Kidney Disease: Improving Global Outcomes) guidelines suggest to implement preventive strategies in high-risk patients. Definition and classification of acute kidney injury according to the KDIGO criteria are based on an increase in serum creatinine and/or a decrease in urinary output. Renal replacement therapy (RRT) is the only supportive measure in patients with severe AKI...
February 2018: Anästhesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie: AINS
https://www.readbyqxmd.com/read/29422396/cognitive-impairment-in-early-onset-epilepsy-is-associated-with-reduced-left-thalamic-volume
#9
Michael Yoong, Matthew Hunter, Jacqueline Stephen, Alan Quigley, Jeremy Jones, Jay Shetty, Ailsa McLellan, Mark E Bastin, Richard F M Chin
OBJECTIVE: The objective of this study was to investigate whether reduction of thalamic volumes in children with early onset epilepsy (CWEOE) is associated with cognitive impairment. METHODS: This is a nested case-control study including a prospectively recruited cohort of 76 children with newly-diagnosed early onset epilepsy (onset <5years age) and 14 healthy controls presenting to hospitals within NHS Lothian and Fife. Quantitative volumetric analysis of subcortical structures was performed using volumetric T1-weighted magnetic resonance imaging (MRI) and correlated with the results of formal neurocognitive and clinical assessment...
February 5, 2018: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/29420761/chinese-military-evaluation-of-a-portable-near-infrared-detector-of-traumatic-intracranial-hematomas
#10
Chun-Yang Liang, Yang Yang, Chun-Sen Shen, Hai-Jiang Wang, Nai-Ming Liu, Zhi-Wen Wang, Feng-Lei Zhu, Ru-Xiang Xu
Introduction: Secondary brain injury is the main cause of mortality from traumatic brain injury (TBI). One hallmark of TBI is intracranial hemorrhage, which occurs in 40-50% of severe TBI cases. Early identification of intracranial hematomas in TBI patients allows early surgical evacuation and can reduce the case fatality rate of TBI. As pre-hospital care is the weakest part of Chinese emergency care, there is an urgent need for a capability to detect brain hematomas early. In China, in addition to preventing injuries and diseases in military staff and in enhancing the military armed forces during war, military medicine participates in actions such as emergency public health crises, natural disasters, emerging conflicts, and anti-terrorist campaigns during peacetime...
February 6, 2018: Military Medicine
https://www.readbyqxmd.com/read/29417491/meditation-and-yoga-practice-are-associated-with-smaller-right-amygdala-volume-the-rotterdam-study
#11
Rinske A Gotink, Meike W Vernooij, M Arfan Ikram, Wiro J Niessen, Gabriel P Krestin, Albert Hofman, Henning Tiemeier, M G Myriam Hunink
To determine the association between meditation and yoga practice, experienced stress, and amygdala and hippocampal volume in a large population-based study. This study was embedded within the population-based Rotterdam Study and included 3742 participants for cross-sectional association. Participants filled out a questionnaire assessing meditation practice, yoga practice, and experienced stress, and underwent a magnetic resonance scan of the brain. 2397 participants underwent multiple brain scans, and were assessed for structural change over time...
February 7, 2018: Brain Imaging and Behavior
https://www.readbyqxmd.com/read/29413283/effects-of-proton-center-closure-on-pediatric-case-volume-and-resident-education-at-an-academic-cancer-center
#12
James O Galle, David E Long, Tim Lautenschlaeger, Richard C Zellars, Gordon A Watson, Susannah G Ellsworth
PURPOSE: To analyze effects of closure of an academic proton treatment center (PTC) on pediatric case volume, distribution, and resident education. METHODS AND MATERIALS: This was a review of 412 consecutive pediatric (age ≤18 years) cases treated at a single institution from 2012 to 2016. Residents' Accreditation Council for Graduate Medical Education case logs for the same years were also analyzed. Characteristics of the patient population and resident case volumes before and after closure of the PTC are reported...
March 1, 2018: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/29410079/the-marburg-m%C3%A3-nster-affective-disorders-cohort-study-macs-a-quality-assurance-protocol-for-mr-neuroimaging-data
#13
Christoph Vogelbacher, Thomas W D Möbius, Jens Sommer, Verena Schuster, Udo Dannlowski, Tilo Kircher, Astrid Dempfle, Andreas Jansen, Miriam H A Bopp
Large, longitudinal, multi-center MR neuroimaging studies require comprehensive quality assurance (QA) protocols for assessing the general quality of the compiled data, indicating potential malfunctions in the scanning equipment, and evaluating inter-site differences that need to be accounted for in subsequent analyses. We describe the implementation of a QA protocol for functional magnet resonance imaging (fMRI) data based on the regular measurement of an MRI phantom and an extensive variety of currently published QA statistics...
January 31, 2018: NeuroImage
https://www.readbyqxmd.com/read/29394907/the-effect-of-an-intraoperative-lung-protective-ventilation-strategy-in-neurosurgical-patients-undergoing-craniotomy-study-protocol-for-a-randomized-controlled-trial
#14
Liyong Zhang, Wei Xiong, Yuming Peng, Wei Zhang, Ruquan Han
BACKGROUND: Ventilator-induced lung injury is a major cause of postoperative pulmonary complications (PPCs) in patients undergoing neurosurgery after general anesthesia. However, there is no study on the effect of a lung-protective ventilation strategy in patients undergoing neurosurgery. METHODS: This is a single-center, randomized, parallel-group controlled trial which will be carried out at Beijing Tiantan Hospital, Capital Medical University. Three hundred and thirty-four patients undergoing intracranial tumor surgery will be randomly allocated to the control group and the protective-ventilation strategy group...
February 2, 2018: Trials
https://www.readbyqxmd.com/read/29393179/irradiation-of-intracranial-gliomas-in-children
#15
Rolf-Dieter Kortmann, Clemens Seidel, Klaus Müller, Franz Wolfgang Hirsch
Attainment of local control is a cornerstone in the management of brain tumors in children. Treatment of progressive low-grade and all high-grade gliomas traditionally includes resection followed by fractionated radiotherapy (FRT) or FRT alone in neoplasms not amenable to surgical removal. While in younger children chemotherapy is typically used as a first-line non-surgical management option, FRT in such patients remains the standard of salvage therapy. Recent improvements in techniques for radiation treatment planning and delivery allow conformal and selective coverage of the target volume with a prescribed dose, sparing adjacent normal tissues to assure maximal tumor control and minimal toxicity...
2018: Progress in Neurological Surgery
https://www.readbyqxmd.com/read/29393178/brachytherapy-of-intracranial-gliomas
#16
Silke Birgit Nachbichler, Friedrich-Wilhelm Kreth
Interstitial implantation of radioactive materials (brachytherapy [BT]) has been designed to protractedly deliver a high radiation dose to a well-defined target volume, while minimizing irradiation of the adjacent normal tissues. Even though promising results have been reported over time, the role of this treatment modality in the management of brain tumors is still poorly defined, and only a few centers worldwide apply it in clinical practice. Nevertheless, temporary or permanent interstitial implantation of low activity (<20 mCi) and low dose rate (≤10 cGy/h) iodine-125 (125I) seeds as possible therapy of intracranial gliomas is currently undergoing a definite revival, and several indications for its use have been identified...
2018: Progress in Neurological Surgery
https://www.readbyqxmd.com/read/29385018/quantitative-volumetric-imaging-and-clinical-outcome-characterization-of-symptomatic-concussion-in-10-to-14-year-old-adolescent-athletes
#17
Christine L Mac Donald, Jason Barber, Jason Wright, David Coppel, Nina De Lacy, Steve Ottinger, Suzanne Peck, Chris Panks, Kody Zalewski, Samantha Sun, Nancy Temkin
OBJECTIVE: Prior work suggests that younger athletes may be more vulnerable to postconcussive syndrome. We investigated measures of clinical outcome and quantitative volumetric imaging in 10- to 14-year-old adolescent athletes to better understand the impact of concussion on this younger population. SETTING: Outpatient clinics. PARTICIPANTS: Ten- to 14-year-old symptomatic pediatric sports concussion patients and typically developing active controls...
January 30, 2018: Journal of Head Trauma Rehabilitation
https://www.readbyqxmd.com/read/29385016/fatigue-is-associated-with-global-and-regional-thalamic-morphometry-in-veterans-with-a-history-of-mild-traumatic-brain-injury
#18
Alexandra L Clark, Scott F Sorg, Kelsey Holiday, Erin D Bigler, Katherine J Bangen, Nicole D Evangelista, Mark W Bondi, Dawn M Schiehser, Lisa Delano-Wood
OBJECTIVE: Fatigue is a complex, multidimensional phenomenon that commonly occurs following traumatic brain injury (TBI). The thalamus-a structure vulnerable to both primary and secondary injuries in TBI-is thought to play a pivotal role in the manifestation of fatigue. We explored how neuroimaging markers of local and global thalamic morphometry relate to the subjective experience of fatigue post-TBI. METHODS: Sixty-three Veterans with a history of mild TBI underwent structural magnetic resonance imaging and completed questionnaires related to fatigue and psychiatric symptoms...
January 30, 2018: Journal of Head Trauma Rehabilitation
https://www.readbyqxmd.com/read/29383966/antero-posterior-elongation-of-midbrain-in-traumatic-brain-injury-significant-sign-yet-a-mistaken-entity
#19
Raghunath Avanali, Biju Bhadran, Sunil Panchal, Krishna Kumar P, Abhishek V, Kshitij Gulhane, Harison G
BACKGROUND: Antero posterior elongation of the midbrain is observed occasionally in severe traumatic brain injury and generally implies a bad outcome. The objective of the study was to document midbrain elongation and identify the implications of this finding. METHODS: This prospective study included 100 patients with traumatic intracranial haematoma of more than 20 cc in volume. Key measurements were taken in the midbrain and pontine regions and the status of perimesencephalic basal cisterns was noted...
January 31, 2018: British Journal of Neurosurgery
https://www.readbyqxmd.com/read/29381390/associations-between-subclinical-depressive-symptoms-and-reduced-brain-volume-in-middle-aged-to-older-adults
#20
Sarah M Szymkowicz, Adam J Woods, Vonetta M Dotson, Eric C Porges, Nicole R Nissim, Andrew O'Shea, Ronald A Cohen, Natalie C Ebner
OBJECTIVES: The associations between subclinical depressive symptoms, as well specific symptom subscales, on brain structure in aging are not completely elucidated. This study investigated the extent to which depressive symptoms were related to brain volumes in fronto-limbic structures in a sample of middle-aged to older adults. METHOD: Eighty participants underwent structural neuroimaging and completed the Beck Depression Inventory, 2nd Edition (BDI-II), which comprises separate affective, cognitive, and somatic subscales...
January 30, 2018: Aging & Mental Health
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