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Intracranial volume

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https://www.readbyqxmd.com/read/28818998/lower-body-negative-pressure-reduces-optic-nerve-sheath-diameter-during-head-down-tilt
#1
Karina Marshall-Goebel, Robert Terlević, Darius A Gerlach, Simone Kuehn, Edwin Mulder, Jörn Rittweger
The microgravity ocular syndrome (MOS) results in significant structural and functional ophthalmic changes during 6-month spaceflight missions consistent with an increase in cerebrospinal fluid (CSF) pressure compared to the preflight upright position. A ground-based study was performed to assess two of the major hypothesized contributors to MOS, headward fluid shifting and increased ambient CO2, on intracranial and periorbital CSF. In addition, lower body negative pressure (LBNP) was assessed as a countermeasure to headward fluid shifting...
August 17, 2017: Journal of Applied Physiology
https://www.readbyqxmd.com/read/28816146/quality-assessment-of-stereotactic-radiosurgery-of-a-melanoma-brain-metastases-model-using-a-mouselike-phantom-and-the-small-animal-radiation-research-platform
#2
Cheng-Chia Wu, Kunal R Chaudhary, Yong Hum Na, David Welch, Paul J Black, Adam M Sonabend, Peter Canoll, Yvonne M Saenger, Tony J C Wang, Cheng-Shie Wuu, Tom K Hei, Simon K Cheng
PURPOSE: To establish a novel preclinical model for stereotactic radiosurgery (SRS) with combined mouselike phantom quality assurance in the setting of brain metastases. METHODS AND MATERIALS: C57B6 mice underwent intracranial injection of B16-F10 melanoma cells. T1-weighted postcontrast magnetic resonance imaging (MRI) was performed on day 11 after injection. The MRI images were fused with cone beam computed tomography (CBCT) images using the Small Animal Radiation Research Platform (SARRP)...
September 1, 2017: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/28814931/prediction-of-histological-grade-and-completeness-of-resection-of-intracranial-meningiomas-role-of-peritumoural-brain-edema
#3
Kamalanathan Palaniandy, Mohammad Saffari Mohammad Haspani, Norzaini Rose Mohd Zain
BACKGROUND: Meningioma is the commonest primary intracranial tumour in adults. Excision is curative for low grade meningioma, whereas high-grade meningioma requires adjuvant therapy following surgery. Several studies have examined the association between peritumoural brain Edema - a common feature in meningioma - and histological grading with mixed results. The present study attempted to elucidate this association and if peritumoural brain Edema affects the intra-operative judgement of surgeons on the completeness of resection...
May 2017: Malaysian Journal of Medical Sciences: MJMS
https://www.readbyqxmd.com/read/28809859/do-regional-brain-volumes-and-major-depressive-disorder-share-genetic-architecture-a-study-of-generation-scotland-n-19%C3%A2-762-uk-biobank-n-24%C3%A2-048-and-the-english-longitudinal-study-of-ageing-n-5766
#4
E M Wigmore, T-K Clarke, D M Howard, M J Adams, L S Hall, Y Zeng, J Gibson, G Davies, A M Fernandez-Pujals, P A Thomson, C Hayward, B H Smith, L J Hocking, S Padmanabhan, I J Deary, D J Porteous, K K Nicodemus, A M McIntosh
Major depressive disorder (MDD) is a heritable and highly debilitating condition. It is commonly associated with subcortical volumetric abnormalities, the most replicated of these being reduced hippocampal volume. Using the most recent published data from Enhancing Neuroimaging Genetics through Meta-analysis (ENIGMA) consortium's genome-wide association study of regional brain volume, we sought to test whether there is shared genetic architecture between seven subcortical brain volumes and intracranial volume (ICV) and MDD...
August 15, 2017: Translational Psychiatry
https://www.readbyqxmd.com/read/28800199/intracranial-elastance-is-increased-in-idiopathic-intracranial-hypertension
#5
Jason T Chisholm, Padmaja Sudhakar, Abdulnasser N Alhajeri, Jonathan H Smith
BACKGROUND: To date, no pathophysiologic model has sufficiently accounted for all the findings encountered in patients with idiopathic intracranial hypertension (IIH). Intracranial elastance is an index of volume-buffering capacity known to play a role in certain disorders of CSF dynamics, which has not been previously investigated in relation to IIH patients. METHODS: Single-center retrospective cohort study from July 1, 2011 to July 1, 2016. We collected values for opening pressure (PO ), closing pressure (PC ), volume (V) of CSF removed, as well as demographic and clinical covariates...
August 11, 2017: European Journal of Neurology: the Official Journal of the European Federation of Neurological Societies
https://www.readbyqxmd.com/read/28797752/efficacy-of-continuous-positive-airway-pressure-and-incentive-spirometry-on-respiratory-functions-during-the-postoperative-period-following-supratentorial-craniotomy-a-prospective-randomized-controlled-study
#6
Hulya Kahraman Sah, Eren Fatma Akcil, Yusuf Tunali, Hayriye Vehid, Ozlem Korkmaz Dilmen
STUDY OBJECTIVE: Volume controlled ventilation with low PEEP is used in neuro-anesthesia to provide constant PaCO2 levels and prevent raised intracranial pressure. Therefore, neurosurgery patients prone to atelectasis formation, however, we could not find any study that evaluates prevention of postoperative pulmonary complications in neurosurgery. DESIGN: A prospective, randomized controlled study. SETTING: Intensive care unit in a university hospital in Istanbul...
August 7, 2017: Journal of Clinical Anesthesia
https://www.readbyqxmd.com/read/28794252/white-matter-hyperintensity-reduction-and-outcomes-after-minor-stroke
#7
Joanna M Wardlaw, Francesca M Chappell, Maria Del Carmen Valdés Hernández, Stephen D J Makin, Julie Staals, Kirsten Shuler, Michael J Thrippleton, Paul A Armitage, Susana Muñoz-Maniega, Anna K Heye, Eleni Sakka, Martin S Dennis
OBJECTIVE: To assess factors associated with white matter hyperintensity (WMH) change in a large cohort after observing obvious WMH shrinkage 1 year after minor stroke in several participants in a longitudinal study. METHODS: We recruited participants with minor ischemic stroke and performed clinical assessments and brain MRI. At 1 year, we assessed recurrent cerebrovascular events and dependency and repeated the MRI. We assessed change in WMH volume from baseline to 1 year (normalized to percent intracranial volume [ICV]) and associations with baseline variables, clinical outcomes, and imaging parameters using multivariable analysis of covariance, model of changes, and multinomial logistic regression...
August 9, 2017: Neurology
https://www.readbyqxmd.com/read/28791520/external-ventricular-drain-causes-brain-tissue-damage-an-imaging-study
#8
Fabrizio Ortolano, Marco Carbonara, Antonella Stanco, Vittorio Civelli, Giorgio Carrabba, Tommaso Zoerle, Nino Stocchetti
BACKGROUND: An external ventricular drain (EVD) is used to measure intracranial pressure (ICP) and to drain cerebrospinal fluid (CSF). The procedure is generally safe, but parenchymal sequelae are reported as a possible side effect, with variable incidence. We investigated the mechanical sequelae of EVD insertion and their clinical significance in acute brain-injured patients, with a special focus on hemorrhagic lesions. METHODS: Mechanical sequelae of EVD insertion were detected in patients by computed tomography (CT) and magnetic resonance imaging (MRI), performed for clinical purposes...
August 8, 2017: Acta Neurochirurgica
https://www.readbyqxmd.com/read/28791500/correlation-of-volumetric-growth-and-histological-grade-in-50-meningiomas
#9
Wai Cheong Soon, Daniel M Fountain, Kacper Koczyk, Mutwakil Abdulla, Sachin Giri, Kieren Allinson, Tomasz Matys, Mathew R Guilfoyle, Ramez W Kirollos, Thomas Santarius
INTRODUCTION: Advances in radiological imaging techniques have enabled volumetric measurements of meningiomas to be easily monitored using serial imaging scans. There is limited literature on the relationship between tumour growth rates and the WHO classification of meningiomas despite tumour growth being a major determinant of type and timing of intervention. Volumetric growth has been successfully used to assess growth of low-grade glioma; however, there is limited information on the volumetric growth rate (VGR) of meningiomas...
August 9, 2017: Acta Neurochirurgica
https://www.readbyqxmd.com/read/28780516/diagnosis-of-endocrine-disease-primary-empty-sella-a-comprehensive-review
#10
Sabrina Chiloiro, Antonella Giampietro, Antonio Bianchi, Tommaso Tartaglione, Antonio Capobianco, Carmelo Anile, Laura De Marinis
Primary empty sella (PES) is characterized by the herniation of the subarachnoid space within the sella, which is often associated with variable degree of flattening of the pituitary gland in patients without previous pituitary pathologies. PES pathogenetic mechanism are not well known but seem due to a sellar diaphragm incompetence, associated to the occurrence of upper sellar or pituitary factors, as intracranial hypertension and change of pituitary volume. As PES represents in majority of cases a neuroradiological findings, without any clinical implication, the occurrence of endocrine, neurological and opthalmological symptoms, due to the above describes anatomical alteration, delineates the so called PES syndrome...
August 5, 2017: European Journal of Endocrinology
https://www.readbyqxmd.com/read/28777075/numerical-evaluation-of-the-skull-for-human-neuromodulation-with-transcranial-focused-ultrasound
#11
Jerel K Mueller, Leo Ai, Priya Bansal, Wynn Legon
OBJECTIVE: Transcranial focused ultrasound is an emerging field for human non-invasive neuromodulation, but its dosing in humans is difficult to know due to the skull. The objective of the present study was to establish modeling methods based on medical images to assess skull differences between individuals on the wave propagation of ultrasound. APPROACH: Computational models of transcranial focused ultrasound were constructed using CT and MR scans to solve for intracranial pressure...
August 4, 2017: Journal of Neural Engineering
https://www.readbyqxmd.com/read/28777023/impact-of-neurosurgeon-specialization-on-patient-outcomes-for-intracranial-and-spinal-surgery-a-retrospective-analysis-of-the-nationwide-inpatient-sample-1998-2009
#12
Brandon A McCutcheon, Brian R Hirshman, Brandon C Gabel, Michael W Heffner, Logan P Marcus, Tyler S Cole, Clark C Chen, David C Chang, Bob S Carter
OBJECTIVE The subspecialization of neurosurgical practice is an ongoing trend in modern neurosurgery. However, it remains unclear whether the degree of surgeon specialization is associated with improved patient outcomes. The authors hypothesized that a trend toward increased neurosurgeon specialization was associated with improved patient morbidity and mortality rates. METHODS The Nationwide Inpatient Sample (NIS) was used (1998-2009). Patients were included in a spinal analysis cohort for instrumented spine surgery involving the cervical spine ( International Classification of Diseases, Ninth Revision, Clinical Modification [ICD-9-CM] codes 81...
August 4, 2017: Journal of Neurosurgery
https://www.readbyqxmd.com/read/28776680/genistein-exerts-potent-antitumour-effects-alongside-anaesthetic-propofol-by-suppressing-cell-proliferation-and-nuclear-factor-%C3%AE%C2%BAb-mediated-signalling-and-through-upregulating-microrna-218-expression-in-an-intracranial-rat-brain-tumour-model
#13
Yuzhen Zheng, Haigen Liu, Yu Liang
OBJECTIVE: This study was implemented to evaluate the effect of genistein and propofol on intracranial tumour model. METHODS: Male Fischer 344 rats were subjected to intracranial implantation of 9L gliosarcoma cells. Genistein (100 or 200 mg/kg b.wt) was administered orally regularly from 3rd day after implantation to 25th day. Propofol (20 mg/kg; i.p.) was administered once every 5 days till 25th day and was administered 2 h after genistein. KEY FINDINGS: Human gliosarcoma cells (U251) exposed to genistein (12...
August 4, 2017: Journal of Pharmacy and Pharmacology
https://www.readbyqxmd.com/read/28771634/regional-gray-matter-correlates-of-memory-for-emotion-laden-words-in-middle-aged-and-older-adults-a-voxel-based-morphometry-study
#14
Carina Saarela, Juho Joutsa, Matti Laine, Riitta Parkkola, Juha O Rinne, Mira Karrasch
Emotional content is known to enhance memory in a content-dependent manner in healthy populations. In middle-aged and older adults, a reduced preference for negative material, or even an enhanced preference for positive material has been observed. This preference seems to be modulated by the emotional arousal that the material evokes. The neuroanatomical basis for emotional memory processes is, however, not well understood in middle-aged and older healthy people. Previous research on local gray matter correlates of emotional memory in older populations has mainly been conducted with patients suffering from various neurodegenerative diseases...
2017: PloS One
https://www.readbyqxmd.com/read/28769863/application-of-texture-analysis-to-study-small-vessel-disease-and-blood-brain-barrier-integrity
#15
Maria Del C Valdés Hernández, Victor González-Castro, Francesca M Chappell, Eleni Sakka, Stephen Makin, Paul A Armitage, William H Nailon, Joanna M Wardlaw
OBJECTIVES: We evaluate the alternative use of texture analysis for evaluating the role of blood-brain barrier (BBB) in small vessel disease (SVD). METHODS: We used brain magnetic resonance imaging from 204 stroke patients, acquired before and 20 min after intravenous gadolinium administration. We segmented tissues, white matter hyperintensities (WMH) and applied validated visual scores. We measured textural features in all tissues pre- and post-contrast and used ANCOVA to evaluate the effect of SVD indicators on the pre-/post-contrast change, Kruskal-Wallis for significance between patient groups and linear mixed models for pre-/post-contrast variations in cerebrospinal fluid (CSF) with Fazekas scores...
2017: Frontiers in Neurology
https://www.readbyqxmd.com/read/28769857/hyperventilation-therapy-for-control-of-posttraumatic-intracranial-hypertension
#16
REVIEW
Daniel Agustín Godoy, Ali Seifi, David Garza, Santiago Lubillo-Montenegro, Francisco Murillo-Cabezas
During traumatic brain injury, intracranial hypertension (ICH) can become a life-threatening condition if it is not managed quickly and adequately. Physicians use therapeutic hyperventilation to reduce elevated intracranial pressure (ICP) by manipulating autoregulatory functions connected to cerebrovascular CO2 reactivity. Inducing hypocapnia via hyperventilation reduces the partial pressure of arterial carbon dioxide (PaCO2), which incites vasoconstriction in the cerebral resistance arterioles. This constriction decrease cerebral blood flow, which reduces cerebral blood volume and, ultimately, decreases the patient's ICP...
2017: Frontiers in Neurology
https://www.readbyqxmd.com/read/28766174/discriminant-analysis-of-intracranial-volumetric-variables-in-patients-with-normal-pressure-hydrocephalus-and-brain-atrophy
#17
Leszek Czerwosz, Ewa Szczepek, Krzysztof Nowiński, Beata Sokołowska, Jerzy Jurkiewicz, Zbigniew Czernicki, Waldemar Koszewski
A method was developed for the computerized volumetric assessment of the intracranial cerebrospinal fluid (CSF) distribution. The study involved 62 patients differentiated into two groups: with CSF resorption disorders (normal pressure hydrocephalus - 30 patients) and without CSF resorption disorders (various types of brain atrophy - 32 patients). The goal of the study was to ascertain whether the assessment, depending on the linear discriminant analysis of volumetric brain features, could be an effective tool differentiating the two groups...
August 2, 2017: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/28765995/quantification-of-myelin-in-children-using-multiparametric-quantitative-mri-a-pilot-study
#18
Hyun Gi Kim, Won-Jin Moon, JinJoo Han, Jin Wook Choi
PURPOSE: The purpose of this study was to evaluate the usefulness of multiparametric quantitative MRI for myelination quantification in children. METHODS: We examined 22 children (age 0-14 years) with multiparametric quantitative MRI. The total volume of myelin partial volume (Msum), the percentage of Msum within the whole brain parenchyma (Mbpv), and the percentage of Msum within the intracranial volume (Micv) were obtained. Four developmental models of myelin maturation (the logarithmic, logistic, Gompertz, and modified Gompertz models) were examined to find the most representative model of the three parameters...
August 1, 2017: Neuroradiology
https://www.readbyqxmd.com/read/28762185/consideration-of-the-intracranial-pressure-threshold-value-for-the-initiation-of-traumatic-brain-injury-treatment-a-xenon-ct-and-perfusion-ct-study
#19
Mitsuru Honda, Ryo Ichibayashi, Ginga Suzuki, Hiroki Yokomuro, Yoshikatsu Seiki, Shigeru Sase, Taichi Kishi
BACKGROUND: Monitoring of intracranial pressure (ICP) is considered to be fundamental for the care of patients with severe traumatic brain injury (TBI) and is routinely used to direct medical and surgical therapy. Accordingly, some guidelines for the management of severe TBI recommend that treatment be initiated for ICP values >20 mmHg. However, it remained to be accounted whether there is a scientific basis to this instruction. The purpose of the present study was to clarify whether the basis of ICP values >20 mmHg is appropriate...
July 31, 2017: Neurocritical Care
https://www.readbyqxmd.com/read/28762040/case-update-on-cranial-osteopetrosis-which-is-the-role-of-the-neurosurgeon
#20
Irene Stella, Matthieu Vinchon, Pierre Guerreschi, Eva De Berranger, Ikram Bouacha
PURPOSE: Osteopetrosis (OP) is a rare skeletal disease, which can affect the skull base and calvaria. A multidisciplinary approach is mandatory and patient may need neurosurgical care. Few observations have been published, and optimal management of OP is not established yet. METHOD: We report a case of an infant with OP diagnosed at 5 months, who presented signs of intracranial hypertension associated with unilateral blindness. Bone marrow allograft was performed at 6 months of age...
July 31, 2017: Child's Nervous System: ChNS: Official Journal of the International Society for Pediatric Neurosurgery
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