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https://www.readbyqxmd.com/read/28426354/-it-goes-on-everywhere-injection-drug-use-in-canadian-federal-prisons
#1
Emily van der Meulen
BACKGROUND: International and Canadian research on in-prison injection drug use has documented the frequency of its occurrence as well as some of the resulting consequences such as increased prevalence of HIV and hepatitis C virus. Access to prison-based harm reduction programing is thus important. OBJECTIVES: The aim of this study was to learn from former prisoner experiences and insights on in-prison injection drug use in order to advance and improve access to harm reduction options, in particular prison-based needle and syringe programs (PNSPs)...
June 7, 2017: Substance Use & Misuse
https://www.readbyqxmd.com/read/28388352/health-related-quality-of-life-and-receipt-of-women-centred-hiv-care-among-women-living-with-hiv-in-canada
#2
Allison Carter, Mona Loutfy, Alexandra de Pokomandy, Guillaume Colley, Wendy Zhang, Paul Sereda, Nadia O'Brien, Karène Proulx-Boucher, Valerie Nicholson, Kerrigan Beaver, Angela Kaida, On Behalf Of The Chiwos Research Team
We measured health-related quality-of-life (HRQOL) using the SF-12 among women living with HIV (WLWH) in Canada between August 2013 and May 2015. We investigated differences by perceived receipt of women-centered HIV care (WCHC), assessed using an evidence-based definition with a 5-point Likert item: "Overall, I think that the care I have received from my HIV clinic in the last year has been women-centred" (dichotomized into Agree vs. Disagree/Neutral). Of 1308 participants, 26.3% were from British Columbia, 48...
April 7, 2017: Women & Health
https://www.readbyqxmd.com/read/28177965/gastrointestinal-symptom-distress-is-associated-with-worse-mental-and-physical-health-related-quality-of-life
#3
Tyler J OʼNeill, Janet M Raboud, Jill Tinmouth, Sean B Rourke, Sergio Rueda, Trevor A Hart, Curtis Cooper, Anita Rachlis, Ann N Burchell
BACKGROUND: The prevalence of self-reported gastrointestinal (GI) symptoms and distress is high, but few studies have quantified their impact on health-related quality of life (HRQoL). METHODS: We conducted a prospective cohort study of patients with HIV in care in Ontario, Canada (2007-2014). General linear mixed models were used to assess the impact of GI symptoms (diarrhea/soft stool, nausea/vomiting, bloating/painful abdomen, loss of appetite, weight loss/wasting) and distress (range: 0-4) on physical and mental HRQoL summary scores (range: 0-100) measured by the Medical Outcomes Survey SF-36...
May 1, 2017: Journal of Acquired Immune Deficiency Syndromes: JAIDS
https://www.readbyqxmd.com/read/28170303/trends-and-correlates-of-cigarette-smoking-and-its-impacts-on-health-related-quality-of-life-among-people-living-with-hiv-findings-from-the-ontario-hiv-treatment-network-cohort-study-2008-2014
#4
Tsegaye Bekele, Sergio Rueda, Sandra Gardner, Janet Raboud, Marek Smieja, Richard Kennedy, David Fletcher, Ann N Burchell, Jean Bacon, Sean B Rourke
We sought to examine the trends of cigarette smoking, identify correlates of smoking, and examine the impacts of smoking on health-related quality of life (HRQOL) among people living with HIV in Ontario, Canada. Study sample included 4473 individuals receiving care and enrolled in the Ontario HIV Treatment Network Cohort Study. Self-report data on cigarette smoking, HRQOL, and demographic and sociobehavioral variables were collected between 2008 and 2014 through annual face-to-face interviews. Clinical data were abstracted from participants' medical records and enhanced through linkage with a provincial public health laboratory database...
February 2017: AIDS Patient Care and STDs
https://www.readbyqxmd.com/read/28057074/how-acceptable-is-it-for-hiv-positive-african-caribbean-and-black-women-to-provide-breast-milk-fluid-samples-for-research-purposes
#5
MULTICENTER STUDY
L Kapiriri, W Tharao, M Muchenje, I M Khatundi, F Ongoiba
BACKGROUND: The African, Caribbean and Black communities have been found to be reluctant to participate in health research in North America. This is partly attributed to historical experiences as well as their cultural beliefs. Cultural beliefs about the uses of breast milk/fluids could further hinder the participation of African, Caribbean, and Black communities in research involving the collection of breast milk/fluids samples. METHODS: We conducted 17 in-depth interviews and three group interviews (n = 10) with HIV+ African, Caribbean and Black women living in Ontario, Canada to explore their cultural beliefs about breast milk/fluids and their acceptance of participating in research that involves the provision of breast fluid samples...
January 3, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/28027668/social-determinants-of-health-and-retention-in-hiv-care-in-a-clinical-cohort-in-ontario-canada
#6
Beth Rachlis, Ann N Burchell, Sandra Gardner, Lucia Light, Janet Raboud, Tony Antoniou, Jean Bacon, Anita Benoit, Curtis Cooper, Claire Kendall, Mona Loutfy, Wendy Wobeser, Frank McGee, Anita Rachlis, Sean B Rourke
Continuous HIV care supports antiretroviral therapy initiation and adherence, and prolongs survival. We investigated the association of social determinants of health (SDH) and subsequent retention in HIV care in a clinical cohort in Ontario, Canada. The Ontario HIV Treatment Network Cohort Study is a multi-site cohort of patients at 10 HIV clinics. Data were collected from medical charts, interviews, and via record linkage with the provincial public health laboratory for viral load tests. For participants interviewed in 2009, we used three-category multinomial logistic regression to identify predictors of retention in 2010-2012, defined as (1) continuous care (≥2 viral loads ≥90 days in all years; reference category); (2) discontinuous care (only 1 viral load/year in ≥1 year); and (3) a gap in care (≥1 year in 2010-2012 with no viral load)...
December 27, 2016: AIDS Care
https://www.readbyqxmd.com/read/28027664/barriers-and-facilitators-to-hiv-and-sexually-transmitted-infections-testing-for-gay-bisexual-and-other-transgender-men-who-have-sex-with-men
#7
Ayden I Scheim, Robb Travers
Transgender men who have sex with men (trans MSM) may be at elevated risk for HIV and other sexually transmitted infections (STI), and therefore require access to HIV and STI testing services. However, trans people often face stigma, discrimination, and gaps in provider competence when attempting to access health care and may therefore postpone, avoid, or be refused care. In this context, quantitative data have indicated low access to, and uptake of, HIV testing among trans MSM. The present manuscript aimed to identify trans MSM's perspectives on barriers and facilitators to HIV and STI testing...
December 27, 2016: AIDS Care
https://www.readbyqxmd.com/read/27996376/sexual-orientation-disclosure-in-primary-care-settings-by-gay-bisexual-and-other-men-who-have-sex-with-men-in-a-canadian-city
#8
Todd A Coleman, Greta R Bauer, Daniel Pugh, Gloria Aykroyd, Leanne Powell, Rob Newman
PURPOSE: Sexual orientation affects individuals' health histories and is fundamental to providers' understanding of patients as a whole. Gay, bisexual, and other men who have sex with men (GB-MSM) are vulnerable to certain health conditions, including HIV. The aim of this exploratory analysis was to examine factors associated with sexual orientation disclosure and communication with providers about GB-MSM health issues and to discuss implications. METHODS: We conducted a cross-sectional internet survey of GB-MSM (n = 202) in London-Middlesex, Ontario, Canada; analyses were limited to those with a regular primary care provider (n = 173)...
February 2017: LGBT Health
https://www.readbyqxmd.com/read/27984556/a-population-based-study-of-care-at-the-end-of-life-among-people-with-hiv-in-ontario-from-2010-to-2013
#9
Claire E Kendall, Mathieu Chalifoux, Doug Manuel, Robert Reinhard, Gregory Robinson, Jean Bacon, Sean B Rourke, Ron Rosenes, Peter Tanuseputro
BACKGROUND: Aging and increasing comorbidity is changing the end-of-life experience of people living with HIV (PLHIV) in the developed world. We quantified, at a population level, the receipt of health care services and associated costs across a comprehensive set of sectors among decedents with and without HIV. METHODS: We conducted a retrospective population-level observational study of all decedents in Ontario and their receipt of health care services, captured through linked health administrative databases, between April 1, 2010 and March 31, 2013...
May 1, 2017: Journal of Acquired Immune Deficiency Syndromes: JAIDS
https://www.readbyqxmd.com/read/27965866/progesterone-supplementation-for-hiv-positive-pregnant-women-on-protease-inhibitor-based-antiretroviral-regimens-the-prospar-study-a-study-protocol-for-a-pilot-randomized-controlled-trial
#10
Kaitlin Siou, Sharon L Walmsley, Kellie E Murphy, Janet Raboud, Mona Loutfy, Mark H Yudin, Michael Silverman, Noor N Ladhani, Lena Serghides
BACKGROUND: In Canada, the majority of HIV-positive pregnant women receive combination antiretroviral therapy that includes a ritonavir-boosted protease inhibitor to prevent mother-to-child HIV transmission. However, protease inhibitor-based combination antiretroviral therapy has been associated with increased rates of preterm, low birth weight, and small for gestational age births. Our previous experimental findings demonstrate that protease inhibitor use during pregnancy is associated with decreased progesterone levels that correlate with fetal growth, and that progesterone supplementation can improve protease inhibitor-induced fetal growth restriction...
2016: Pilot and Feasibility Studies
https://www.readbyqxmd.com/read/27956646/engagement-in-and-continuity-of-hiv-care-among-african-and-caribbean-black-women-living-with-hiv-in-ontario-canada
#11
Carmen H Logie, Victoria L Kennedy, Wangari Tharao, Uzma Ahmed, Mona R Loutfy
Engagement in care is a key component of the HIV care cascade, yet there are knowledge gaps regarding how to assess HIV care engagement. This study aimed to develop a tool to assess HIV care engagement and to assess associations between HIV care engagement and quality of life (QOL) among African, Caribbean and Black (ACB) women living with HIV (WLWH). We conducted a cross-sectional survey with ACB WLWH across Ontario, Canada. We developed the 'HIV Engagement in and Continuity of Care Scale' (HECCS). We conducted exploratory factor analysis (EFA) and confirmatory factor analysis (CFA) to test the scale's factor structure...
December 12, 2016: International Journal of STD & AIDS
https://www.readbyqxmd.com/read/27922856/health-profiles-and-associated-service-use-among-adults-with-hiv-and-intellectual-and-developmental-disabilities
#12
Yona Lunsky, Anna Durbin, Hilary K Brown, Symron Bansal, Marina Heifetz, Tony Antoniou
OBJECTIVE (S): Due to the commonly held notion that individuals with intellectual and developmental disabilities (IDD) have low risk of HIV acquisition, we compared the prevalence of HIV infection among people with and without IDD. We also examined health status and health service use among the HIV-infected group. DESIGN: Population-based cohort study using linked administrative health and social services databases. METHODS: We compared HIV prevalence between Ontario adults with IDD (n=64,008) and a 20% random sample of Ontario adults without IDD...
December 5, 2016: AIDS
https://www.readbyqxmd.com/read/27802346/prevalence-recurrence-and-incidence-of-current-depressive-symptoms-among-people-living-with-hiv-in-ontario-canada-results-from-the-ontario-hiv-treatment-network-cohort-study
#13
Stephanie K Y Choi, Eleanor Boyle, John Cairney, Evan J Collins, Sandra Gardner, Jean Bacon, Sean B Rourke
INTRODUCTION: Current studies of depression among people living with HIV focus on describing its point prevalence. Given the fluctuating nature of depression and its profound impacts on clinical and quality-of-life outcomes, this study aimed to examine the prevalence, recurrence and incidence of current depressive symptoms and its underlying catalysts longitudinally and systematically among these individuals. METHODS: We conducted a prospective cohort study between October 1, 2007 and December 31, 2012 using longitudinal linked data sources...
2016: PloS One
https://www.readbyqxmd.com/read/27798432/hiv-related-sexual-risk-among-transgender-men-who-are-gay-bisexual-or-have-sex-with-men
#14
Ayden I Scheim, Greta R Bauer, Robb Travers
BACKGROUND: This study is among the first to examine factors associated with HIV-related sexual risk among transgender men and other transmasculine persons who are gay, bisexual, or who have sex with men (T-GBMSM). METHODS: In 2009-2010, 433 transgender people in Ontario, Canada participated in a multi-mode respondent-driven sampling survey, including 158 T-GBMSM. Analyses were weighted using RDS II methods to adjust for differential recruitment probabilities; confidence intervals were adjusted for clustering by shared recruiter...
October 27, 2016: Journal of Acquired Immune Deficiency Syndromes: JAIDS
https://www.readbyqxmd.com/read/27750027/a-structural-equation-model-of-factors-contributing-to-quality-of-life-among-african-and-caribbean-women-living-with-hiv-in-ontario-canada
#15
Carmen H Logie, Uzma Ahmed, Wangari Tharao, Mona R Loutfy
African and Caribbean Black (ACB) women in Canada are disproportionately impacted by new HIV infections. ACB women's HIV vulnerability is shaped by contexts of stigma and discrimination. HIV-related stigma compromises quality of life (QOL) among women living with HIV (WLWH), yet scant research has examined concomitant effects of racial discrimination and HIV-related stigma on QOL. We used data from a cross-sectional survey with ACB WLWH in Ontario (n = 173) to test a conceptual model of pathways between HIV-related stigma, racial discrimination, depression, social support, and QOL...
March 2017: AIDS Research and Human Retroviruses
https://www.readbyqxmd.com/read/27746042/rituximab-in-lymphoma-and-chronic-lymphocytic-leukaemia-a-practice-guideline
#16
A Prica, F Baldassarre, L K Hicks, K Imrie, T Kouroukis, M Cheung
Rituximab is the first monoclonal antibody to be approved for use by the US Food and Drug Administration in cancer. Its role in the treatment of non-Hodgkin lymphoma, including chronic lymphocytic leukaemia (CLL), has evolved significantly. We aimed to systematically review and update the literature on rituximab in lymphoma and CLL, and provide evidence-based consensus guidelines for its rational use. Validated methodology from the Cancer Care Ontario Program in Evidence-based Care was used. A comprehensive literature search was completed by a methodologist from the Hematology Disease Site Group of Cancer Care Ontario...
January 2017: Clinical Oncology: a Journal of the Royal College of Radiologists
https://www.readbyqxmd.com/read/27669510/a-structural-equation-model-of-hiv-related-stigma-racial-discrimination-housing-insecurity-and-wellbeing-among-african-and-caribbean-black-women-living-with-hiv-in-ontario-canada
#17
Carmen H Logie, Jesse I R Jenkinson, Valerie Earnshaw, Wangari Tharao, Mona R Loutfy
African and Caribbean Black women in Canada have new HIV infection rates 7 times higher than their white counterparts. This overrepresentation is situated in structural contexts of inequities that result in social, economic and health disparities among African and Caribbean Black populations. Economic insecurity is a distal driver of HIV vulnerability, reducing access to HIV testing, prevention and care. Less is known about how economic insecurity indicators, such as housing security, continue to influence the lives of women living with HIV following HIV-positive diagnoses...
2016: PloS One
https://www.readbyqxmd.com/read/27607586/sexual-behaviors-among-women-living-with-hiv-in-ontario-canada
#18
Samantha Robinson, Sandra Gardner, Mona Loutfy, Lucia Light, Wangari Tharao, Sean B Rourke, Ann N Burchell
Understanding the sexual activities and partnerships of women living with human immunodeficiency virus (HIV) remains important to promote healthy sexuality and to reduce the transmission of HIV and other sexually transmitted infections. We described sexual behaviors of women living with HIV enrolled in an ongoing study in Ontario, Canada. Data were available from 582 women who self-completed a sexual behavior questionnaire between 2010 and 2012. Nearly half (46.1%) of women reported a sexual partner in the preceding three months; women less likely to be sexually active were older, Black/African, separated, divorced, widowed, single, and unemployed...
May 2017: AIDS Care
https://www.readbyqxmd.com/read/27506468/needs-among-persons-with-human-immunodeficiency-virus-and-intellectual-and-developmental-disabilities-in-community-mental-health-care-a-cross-sectional-study
#19
A Durbin, F Sirotich, Y Lunsky, K Roesslein, J Durbin
BACKGROUND: The experience of having human immunodeficiency virus (HIV) is often associated with co-occurring mental health issues. Community mental health services are an important source of support for persons with HIV living in the community. Persons with intellectual disability (ID) are vulnerable to HIV and may have unique support needs beyond those without ID receiving community care. This study compared support needs of men with HIV in community mental health programmes, with and without ID...
August 10, 2016: Journal of Intellectual Disability Research: JIDR
https://www.readbyqxmd.com/read/27454239/burden-and-risk-factors-for-gastrointestinal-symptom-distress-in-hiv-patients-in-the-modern-antiretroviral-era
#20
Tyler J O'Neill, Janet M Raboud, Jill Tinmouth, Sean B Rourke, Sandra Gardner, Curtis Cooper, Sergio Rueda, Trevor A Hart, Anita Rachlis, Ann N Burchell
In the modern antiretroviral (ARV) era, there is limited knowledge about the prevalence and risk factors for HIV patient-reported gastrointestinal (GI) symptoms (diarrhoea/soft stool, nausea/vomiting, bloating/painful abdomen, loss of appetite, and weight loss/wasting) and distress. We prospectively analysed data (2007-2014) on distressing GI symptoms from the Ontario HIV Treatment Network Cohort Study, which follows people attending HIV clinics. Using generalized estimating equations with a logit link, we estimated the associations of psychosocial, demographic, behavioural, and clinical factors with each GI symptoms compared to asymptomatic and non-bothersome symptoms...
February 2017: AIDS Care
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