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https://www.readbyqxmd.com/read/28700406/the-use-of-multistate-models-to-examine-associations-of-stress-and-adherence-with-transitions-among-hiv-care-states-observed-in-a-clinical-hiv-cohort
#1
Sandra Blitz, Tony Antoniou, Ann Burchell, Sharon Walmsley, Lucia Light, Sandra Gardner, Sean Rourke, Curtis Cooper, Claire Kendall, Mona Loutfy, Anita Rachlis, Wendy Wobeser, Anita Benoit, Janet Raboud
BACKGROUND: The "cascade of care" is a framework for quantifying the trajectory of people with HIV along the continuum of HIV care. We extended this framework to recognize that individuals may transition back and forth between states of care and to identify factors associated with movement among states of care over time, with particular focus on stress, depression and adherence. METHODS: The Ontario HIV Treatment Network Cohort Study is a multisite HIV clinical cohort...
July 3, 2017: Journal of Acquired Immune Deficiency Syndromes: JAIDS
https://www.readbyqxmd.com/read/28678619/high-retention-in-hiv-care-at-a-tertiary-care-centre-in-toronto-canada
#2
Leah Szadkowski, Sharon Walmsley, Ann N Burchell, Evan Collins, Sean B Rourke, Janet Raboud
Poor retention in HIV care is associated with poor clinical outcomes and mortality. Previous studies of predictors of poor retention have been conducted with a wide variety of populations, using different measures of retention, and occasionally have conflicting results. We studied demographic and psychosocial factors associated with inter-visit interval length in a setting of universal health care and modern cART. Patients attending ≥2 appointments with an HIV specialist at the Toronto General Hospital Immunodeficiency Clinic from 2004 to 2013 were studied...
July 5, 2017: AIDS Care
https://www.readbyqxmd.com/read/28625119/sociodemographic-and-health-profile-of-heterosexual-men-living-with-hiv-in-ontario-canada
#3
Kristen M Wheeler, Tony Antoniou, Sandra Gardner, Lucia Light, Ramandip Grewal, Jason Globerman, Winston Husbands, Ann N Burchell
In Ontario, Canada, the number of heterosexual men living with HIV has increased over time, yet they remain an understudied population. The study objective was to describe the sociodemographic and clinical characteristics of this population, using data from a multisite clinical cohort of patients receiving HIV care. Sociodemographic and clinical characteristics of men interviewed between 2010 and 2012 were compared according to their self-identified sexual orientation, followed by multivariable linear and logistic regression to assess the association of sexual orientation with CD4 cell count, viral load, hepatitis C co-infection, self-rated health, and mental health concerns after adjustment for covariates...
July 2017: American Journal of Men's Health
https://www.readbyqxmd.com/read/28621653/increased-mortality-among-indigenous-persons-in-a-multisite-cohort-of-people-living-with-hiv-in-canada
#4
Anita C Benoit, Jaime Younger, Kerrigan Beaver, Randy Jackson, Mona Loutfy, Renée Masching, Tony Nobis, Earl Nowgesic, Doe O'Brien-Teengs, Wanda Whitebird, Art Zoccole, Mark Hull, Denise Jaworsky, Elizabeth Benson, Anita Rachlis, Sean B Rourke, Ann N Burchell, Curtis Cooper, Robert S Hogg, Marina B Klein, Nima Machouf, Julio S G Montaner, Chris Tsoukas, Janet Raboud
OBJECTIVE: Compare all-cause mortality between Indigenous participants and participants of other ethnicities living with HIV initiating combination antiretroviral therapy (cART) in an interprovincial multi-site cohort. METHODS: The Canadian Observational Cohort is a collaboration of 8 cohorts of treatment-naïve persons with HIV initiating cART after January 1, 2000. Participants were followed from the cART initiation date until death or last viral load (VL) test date on or before December 31, 2012...
June 16, 2017: Canadian Journal of Public Health. Revue Canadienne de Santé Publique
https://www.readbyqxmd.com/read/28612475/how-hiv-affects-health-and-service-use-for-adults-with-intellectual-and-developmental-disabilities
#5
A Durbin, H K Brown, S Bansal, T Antoniou, J K H Jung, Y Lunsky
OBJECTIVE(S): Although rates of human immunodeficiency virus (HIV) are similar for individuals with and without intellectual and developmental disabilities (IDD), very little is known about the health needs and service use of those with IDD and HIV. Among a population with IDD, we compared the physical and mental health profiles, as well as general and mental health service use for those with and without HIV. DESIGN: Retrospective cohort study in Ontario, Canada using linked administrative health and social service databases...
July 2017: Journal of Intellectual Disability Research: JIDR
https://www.readbyqxmd.com/read/28559226/physician-s-perceptions-of-telemedicine-in-hiv-care-provision-a-cross-sectional-web-based-survey
#6
Kelly Anderson, Troy Francis, Francisco Ibanez-Carrasco, Jason Globerman
BACKGROUND: Telemedicine, or electronic interactive health care consultation, offers a variety of benefits to both patients and primary care clinicians. However, little is known about the opinions of physicians using these modalities. OBJECTIVE: The aim of this study was to examine physician perceptions, including challenges, risks, and benefits of the use of telemedicine in human immunodeficiency virus (HIV) patient care. METHODS: A Web-based, self-administered, anonymous, cross-sectional survey was sent to physicians known to be providing medical care to patients living with HIV in Ontario, Canada...
May 30, 2017: JMIR Public Health and Surveillance
https://www.readbyqxmd.com/read/28426354/-it-goes-on-everywhere-injection-drug-use-in-canadian-federal-prisons
#7
Emily van der Meulen
BACKGROUND: International and Canadian research on in-prison injection drug use has documented the frequency of its occurrence as well as some of the resulting consequences such as increased prevalence of HIV and hepatitis C virus. Access to prison-based harm reduction programing is thus important. OBJECTIVES: The aim of this study was to learn from former prisoner experiences and insights on in-prison injection drug use in order to advance and improve access to harm reduction options, in particular prison-based needle and syringe programs (PNSPs)...
June 7, 2017: Substance Use & Misuse
https://www.readbyqxmd.com/read/28388352/health-related-quality-of-life-and-receipt-of-women-centered-hiv-care-among-women-living-with-hiv-in-canada
#8
Allison Carter, Mona Loutfy, Alexandra de Pokomandy, Guillaume Colley, Wendy Zhang, Paul Sereda, Nadia O'Brien, Karène Proulx-Boucher, Valerie Nicholson, Kerrigan Beaver, Angela Kaida
We measured health-related quality of life (HRQOL) using the SF-12 among women living with HIV (WLWH) in Canada between August 2013 and May 2015. We investigated differences by perceived receipt of women-centered HIV care (WCHC), assessed using an evidence-based definition with a 5-point Likert item: "Overall, I think that the care I have received from my HIV clinic in the last year has been women-centered" (dichotomized into agree vs. disagree/neutral). Of 1308 participants, 26.3 percent were from British Columbia, 48...
April 7, 2017: Women & Health
https://www.readbyqxmd.com/read/28177965/gastrointestinal-symptom-distress-is-associated-with-worse-mental-and-physical-health-related-quality-of-life
#9
Tyler J OʼNeill, Janet M Raboud, Jill Tinmouth, Sean B Rourke, Sergio Rueda, Trevor A Hart, Curtis Cooper, Anita Rachlis, Ann N Burchell
BACKGROUND: The prevalence of self-reported gastrointestinal (GI) symptoms and distress is high, but few studies have quantified their impact on health-related quality of life (HRQoL). METHODS: We conducted a prospective cohort study of patients with HIV in care in Ontario, Canada (2007-2014). General linear mixed models were used to assess the impact of GI symptoms (diarrhea/soft stool, nausea/vomiting, bloating/painful abdomen, loss of appetite, weight loss/wasting) and distress (range: 0-4) on physical and mental HRQoL summary scores (range: 0-100) measured by the Medical Outcomes Survey SF-36...
May 1, 2017: Journal of Acquired Immune Deficiency Syndromes: JAIDS
https://www.readbyqxmd.com/read/28170303/trends-and-correlates-of-cigarette-smoking-and-its-impacts-on-health-related-quality-of-life-among-people-living-with-hiv-findings-from-the-ontario-hiv-treatment-network-cohort-study-2008-2014
#10
Tsegaye Bekele, Sergio Rueda, Sandra Gardner, Janet Raboud, Marek Smieja, Richard Kennedy, David Fletcher, Ann N Burchell, Jean Bacon, Sean B Rourke
We sought to examine the trends of cigarette smoking, identify correlates of smoking, and examine the impacts of smoking on health-related quality of life (HRQOL) among people living with HIV in Ontario, Canada. Study sample included 4473 individuals receiving care and enrolled in the Ontario HIV Treatment Network Cohort Study. Self-report data on cigarette smoking, HRQOL, and demographic and sociobehavioral variables were collected between 2008 and 2014 through annual face-to-face interviews. Clinical data were abstracted from participants' medical records and enhanced through linkage with a provincial public health laboratory database...
February 2017: AIDS Patient Care and STDs
https://www.readbyqxmd.com/read/28057074/how-acceptable-is-it-for-hiv-positive-african-caribbean-and-black-women-to-provide-breast-milk-fluid-samples-for-research-purposes
#11
MULTICENTER STUDY
L Kapiriri, W Tharao, M Muchenje, I M Khatundi, F Ongoiba
BACKGROUND: The African, Caribbean and Black communities have been found to be reluctant to participate in health research in North America. This is partly attributed to historical experiences as well as their cultural beliefs. Cultural beliefs about the uses of breast milk/fluids could further hinder the participation of African, Caribbean, and Black communities in research involving the collection of breast milk/fluids samples. METHODS: We conducted 17 in-depth interviews and three group interviews (n = 10) with HIV+ African, Caribbean and Black women living in Ontario, Canada to explore their cultural beliefs about breast milk/fluids and their acceptance of participating in research that involves the provision of breast fluid samples...
January 3, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/28027668/social-determinants-of-health-and-retention-in-hiv-care-in-a-clinical-cohort-in-ontario-canada
#12
Beth Rachlis, Ann N Burchell, Sandra Gardner, Lucia Light, Janet Raboud, Tony Antoniou, Jean Bacon, Anita Benoit, Curtis Cooper, Claire Kendall, Mona Loutfy, Wendy Wobeser, Frank McGee, Anita Rachlis, Sean B Rourke
Continuous HIV care supports antiretroviral therapy initiation and adherence, and prolongs survival. We investigated the association of social determinants of health (SDH) and subsequent retention in HIV care in a clinical cohort in Ontario, Canada. The Ontario HIV Treatment Network Cohort Study is a multi-site cohort of patients at 10 HIV clinics. Data were collected from medical charts, interviews, and via record linkage with the provincial public health laboratory for viral load tests. For participants interviewed in 2009, we used three-category multinomial logistic regression to identify predictors of retention in 2010-2012, defined as (1) continuous care (≥2 viral loads ≥90 days in all years; reference category); (2) discontinuous care (only 1 viral load/year in ≥1 year); and (3) a gap in care (≥1 year in 2010-2012 with no viral load)...
December 27, 2016: AIDS Care
https://www.readbyqxmd.com/read/28027664/barriers-and-facilitators-to-hiv-and-sexually-transmitted-infections-testing-for-gay-bisexual-and-other-transgender-men-who-have-sex-with-men
#13
Ayden I Scheim, Robb Travers
Transgender men who have sex with men (trans MSM) may be at elevated risk for HIV and other sexually transmitted infections (STI), and therefore require access to HIV and STI testing services. However, trans people often face stigma, discrimination, and gaps in provider competence when attempting to access health care and may therefore postpone, avoid, or be refused care. In this context, quantitative data have indicated low access to, and uptake of, HIV testing among trans MSM. The present manuscript aimed to identify trans MSM's perspectives on barriers and facilitators to HIV and STI testing...
December 27, 2016: AIDS Care
https://www.readbyqxmd.com/read/27996376/sexual-orientation-disclosure-in-primary-care-settings-by-gay-bisexual-and-other-men-who-have-sex-with-men-in-a-canadian-city
#14
Todd A Coleman, Greta R Bauer, Daniel Pugh, Gloria Aykroyd, Leanne Powell, Rob Newman
PURPOSE: Sexual orientation affects individuals' health histories and is fundamental to providers' understanding of patients as a whole. Gay, bisexual, and other men who have sex with men (GB-MSM) are vulnerable to certain health conditions, including HIV. The aim of this exploratory analysis was to examine factors associated with sexual orientation disclosure and communication with providers about GB-MSM health issues and to discuss implications. METHODS: We conducted a cross-sectional internet survey of GB-MSM (n = 202) in London-Middlesex, Ontario, Canada; analyses were limited to those with a regular primary care provider (n = 173)...
February 2017: LGBT Health
https://www.readbyqxmd.com/read/27984556/a-population-based-study-of-care-at-the-end-of-life-among-people-with-hiv-in-ontario-from-2010-to-2013
#15
Claire E Kendall, Mathieu Chalifoux, Doug Manuel, Robert Reinhard, Gregory Robinson, Jean Bacon, Sean B Rourke, Ron Rosenes, Peter Tanuseputro
BACKGROUND: Aging and increasing comorbidity is changing the end-of-life experience of people living with HIV (PLHIV) in the developed world. We quantified, at a population level, the receipt of health care services and associated costs across a comprehensive set of sectors among decedents with and without HIV. METHODS: We conducted a retrospective population-level observational study of all decedents in Ontario and their receipt of health care services, captured through linked health administrative databases, between April 1, 2010 and March 31, 2013...
May 1, 2017: Journal of Acquired Immune Deficiency Syndromes: JAIDS
https://www.readbyqxmd.com/read/27965866/progesterone-supplementation-for-hiv-positive-pregnant-women-on-protease-inhibitor-based-antiretroviral-regimens-the-prospar-study-a-study-protocol-for-a-pilot-randomized-controlled-trial
#16
Kaitlin Siou, Sharon L Walmsley, Kellie E Murphy, Janet Raboud, Mona Loutfy, Mark H Yudin, Michael Silverman, Noor N Ladhani, Lena Serghides
BACKGROUND: In Canada, the majority of HIV-positive pregnant women receive combination antiretroviral therapy that includes a ritonavir-boosted protease inhibitor to prevent mother-to-child HIV transmission. However, protease inhibitor-based combination antiretroviral therapy has been associated with increased rates of preterm, low birth weight, and small for gestational age births. Our previous experimental findings demonstrate that protease inhibitor use during pregnancy is associated with decreased progesterone levels that correlate with fetal growth, and that progesterone supplementation can improve protease inhibitor-induced fetal growth restriction...
2016: Pilot and Feasibility Studies
https://www.readbyqxmd.com/read/27956646/engagement-in-and-continuity-of-hiv-care-among-african-and-caribbean-black-women-living-with-hiv-in-ontario-canada
#17
Carmen H Logie, Victoria L Kennedy, Wangari Tharao, Uzma Ahmed, Mona R Loutfy
Engagement in care is a key component of the HIV care cascade, yet there are knowledge gaps regarding how to assess HIV care engagement. This study aimed to develop a tool to assess HIV care engagement and to assess associations between HIV care engagement and quality of life (QOL) among African, Caribbean and Black (ACB) women living with HIV (WLWH). We conducted a cross-sectional survey with ACB WLWH across Ontario, Canada. We developed the 'HIV Engagement in and Continuity of Care Scale' (HECCS). We conducted exploratory factor analysis (EFA) and confirmatory factor analysis (CFA) to test the scale's factor structure...
December 12, 2016: International Journal of STD & AIDS
https://www.readbyqxmd.com/read/27922856/health-profiles-and-associated-service-use-among-adults-with-hiv-and-intellectual-and-developmental-disabilities
#18
Yona Lunsky, Anna Durbin, Hilary K Brown, Symron Bansal, Marina Heifetz, Tony Antoniou
OBJECTIVE (S): Due to the commonly held notion that individuals with intellectual and developmental disabilities (IDD) have low risk of HIV acquisition, we compared the prevalence of HIV infection among people with and without IDD. We also examined health status and health service use among the HIV-infected group. DESIGN: Population-based cohort study using linked administrative health and social services databases. METHODS: We compared HIV prevalence between Ontario adults with IDD (n=64,008) and a 20% random sample of Ontario adults without IDD...
December 5, 2016: AIDS
https://www.readbyqxmd.com/read/27802346/prevalence-recurrence-and-incidence-of-current-depressive-symptoms-among-people-living-with-hiv-in-ontario-canada-results-from-the-ontario-hiv-treatment-network-cohort-study
#19
Stephanie K Y Choi, Eleanor Boyle, John Cairney, Evan J Collins, Sandra Gardner, Jean Bacon, Sean B Rourke
INTRODUCTION: Current studies of depression among people living with HIV focus on describing its point prevalence. Given the fluctuating nature of depression and its profound impacts on clinical and quality-of-life outcomes, this study aimed to examine the prevalence, recurrence and incidence of current depressive symptoms and its underlying catalysts longitudinally and systematically among these individuals. METHODS: We conducted a prospective cohort study between October 1, 2007 and December 31, 2012 using longitudinal linked data sources...
2016: PloS One
https://www.readbyqxmd.com/read/27798432/hiv-related-sexual-risk-among-transgender-men-who-are-gay-bisexual-or-have-sex-with-men
#20
Ayden I Scheim, Greta R Bauer, Robb Travers
BACKGROUND: This study is among the first to examine factors associated with HIV-related sexual risk among transgender men and other transmasculine persons who are gay, bisexual, or have sex with men (T-GBMSM). METHODS: In 2009-2010, 433 transgender people in Ontario, Canada, participated in a multimode respondent-driven sampling survey, including 158 T-GBMSM. Analyses were weighted using respondent-driven sampling II methods to adjust for differential recruitment probabilities; confidence intervals (CI) were adjusted for clustering by shared recruiter...
April 1, 2017: Journal of Acquired Immune Deficiency Syndromes: JAIDS
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