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https://www.readbyqxmd.com/read/29053912/community-based-screening-of-hepatitis-c-with-a-one-step-rna-detection-algorithm-from-dried-blood-spots-analysis-of-key-populations-in-barcelona-spain
#1
V Saludes, C Folch, A Morales-Carmona, L Ferrer, L Fernández, R Muñoz, M Jiménez, E Loureiro, P Fernández-Dávila, E Bascuñana, J Casabona, E Martró
Alternative strategies are required to enhance the diagnosis of silent hepatitis C virus (HCV) infections in hard-to-reach key populations at risk. Among them, HCV prevalence and bio-behavioural data is scarce for HIV-negative men who have sex with men (MSM) and men and trans-women sex workers. We sought to describe and assess the potential benefits of a community-based one-step HCV screening and confirmatory strategy for these populations in Barcelona. The screening strategy based on a real-time RT-PCR assay for HCV-RNA detection in dried-blood spots (DBS) was validated and implemented in addition to an antibody point-of-care test in a community centre...
October 20, 2017: Journal of Viral Hepatitis
https://www.readbyqxmd.com/read/29053737/screening-for-hiv-hepatitis-b-and-syphilis-on-dried-blood-spots-a-promising-method-to-better-reach-hidden-high-risk-populations-with-self-collected-sampling
#2
Inge H M van Loo, Nicole H T M Dukers-Muijrers, Rosalie Heuts, Marianne A B van der Sande, Christian J P A Hoebe
INTRODUCTION: Many people at high risk for sexually transmitted infections (STIs), e.g., men who have sex with men (MSM), are not optimally reached by current sexual health care systems with testing. To facilitate testing by home-based sampling or sampling in outreach setting we evaluated dried blood spots (DBS), a method for self-collected blood sampling for serological screening of HIV, hepatitis B (HBV) and syphilis. The aims of this study were to assess the acceptability and feasibility of self-collected DBS and to compare the test results for screening of HIV, HBV and syphilis from DBS with blood drawn by venous puncture...
2017: PloS One
https://www.readbyqxmd.com/read/29053647/efficacy-of-different-methods-used-for-dry-socket-prevention-and-risk-factor-analysis-a-systematic-review
#3
M Taberner-Vallverdú, M-Á Sánchez-Garcés, C Gay-Escoda
BACKGROUND: Dry socket is one of the most common complications that develops after the extraction of a permanent tooth, and its prevention is more effective than its treatment. OBJECTIVES: Analyze the efficacy of different methods used in preventing dry socket in order to decrease its incidence after tooth extraction. MATERIAL AND METHODS: A Cochrane and PubMed-MEDLINE database search was conducted with the search terms "dry socket", "prevention", "risk factors", "alveolar osteitis" and "fibrynolitic alveolitis", both individually and using the Boolean operator "AND"...
October 20, 2017: Medicina Oral, Patología Oral y Cirugía Bucal
https://www.readbyqxmd.com/read/29053437/reaching-egyptian-gays-using-social-media-a-comprehensive-health-study-and-a-framework-for-future-research
#4
Ahmed Gamal Elmahy
Internet has revolutionized research on sexual minorities by providing direct and safe access to hidden, stigmatized and high risk populations. This study investigated the possibility of using Facebook to reach Egyptian gays. The questionnaire was manually distributed to an extensive list of Facebook pages and groups related to the topic that has been collected using a snowball-like technique. The recruitment lasted from August 2015 to May 2016. Among the 461 eligible participants, the mean age was 26.6 (SD = 7...
October 20, 2017: Journal of Homosexuality
https://www.readbyqxmd.com/read/29053409/amnestic-heterosexism-and-bystander-responses-to-anti-gay-bullying
#5
Jennifer Katz, Dillon Federici, Tess Ramos-Dries
Amnestic heterosexism (AH) reflects the belief that, in contemporary society, people who are lesbian, gay, or bisexual (LGB) no longer experience discrimination related to sexual orientation. We investigated potential associations between individuals' AH beliefs and their responses to anti-gay bullying. Heterosexual undergraduates (N = 238) completed a measure of AH before responding to a scenario in which a man accuses another man of being a "fag." As expected, those with greater AH beliefs perceived the situation as less severe/dangerous, felt less personally responsible to intervene, and were more blaming toward the target of bullying...
October 20, 2017: Journal of Homosexuality
https://www.readbyqxmd.com/read/29053225/histological-outcomes-of-anal-high-grade-cytopredictions
#6
Jennifer Margaret Roberts, Fengyi Jin, Isobel Mary Poynten, Carmella Law, David James Templeton, Julia Kathleen Thurloe, Suzanne Marie Garland, Andrew Edwin Grulich, Annabelle Farnsworth, Richard John Hillman
BACKGROUND: Longitudinal studies of histological outcomes after anal cytological screening in men who have sex with men (MSM) are rare. This study measured the positive predictive values (PPVs) of each level of baseline cytological abnormality in MSM in Sydney, Australia, over a 12-month period. METHODS: The Study of the Prevention of Anal Cancer is a 3-year prospective study of the natural history of anal human papillomavirus infection in MSM at least 35 years old...
October 20, 2017: Cancer
https://www.readbyqxmd.com/read/29049540/feasibility-process-and-outcomes-of-cardiovascular-clinical-trial-data-sharing-a-reproduction-analysis-of-the-smart-af-trial
#7
Hawkins C Gay, Abigail S Baldridge, Mark D Huffman
Importance: Data sharing is as an expanding initiative for enhancing trust in the clinical research enterprise. Objective: To evaluate the feasibility, process, and outcomes of a reproduction analysis of the THERMOCOOL SMARTTOUCH Catheter for the Treatment of Symptomatic Paroxysmal Atrial Fibrillation (SMART-AF) trial using shared clinical trial data. Design, Setting, and Participants: A reproduction analysis of the SMART-AF trial was performed using the data sets, data dictionary, case report file, and statistical analysis plan from the original trial accessed through the Yale Open Data Access Project using the SAS Clinical Trials Data Transparency platform...
October 18, 2017: JAMA Cardiology
https://www.readbyqxmd.com/read/29049497/optimizing-the-clinical-care-of-lesbian-gay-bisexual-and-transgender-older-adults
#8
Alexia M Torke, Jennifer L Carnahan
No abstract text is available yet for this article.
October 16, 2017: JAMA Internal Medicine
https://www.readbyqxmd.com/read/29048306/subtle-and-blatant-perceived-discrimination-and-well-being-in-lesbians-and-gay-men-in-spain-the-role-of-social-support
#9
Fernando Molero, Prado Silván-Ferrero, María J Fuster-Ruiz de Apodaca, Encarnación Nouvilas-Pallejá, Daniel Pérez-Garín
BACKGROUND: The situation of lesbians and gay men (LGs) in Spain has improved significantly in recent decades. However, Spanish society still exhibits prejudice and discrimination. The current study pursues three main goals: 1) to analyse the extent to which LGs perceive blatant and subtle discrimination, 2) to explore the relationship between perceived discrimination and LGs’ psychological and subjective well-being, and 3) to analyse the possible mediational role of social support in reducing the negative influence of perceived discrimination on well-being...
November 2017: Psicothema
https://www.readbyqxmd.com/read/29048252/stigma-communication-surrounding-prep-the-experiences-of-a-sample-of-men-who-have-sex-with-men
#10
Joseph Schwartz, Josh Grimm
HIV is a serious problem in the USA, particularly for men who have sex with men (MSM). A new means of HIV prevention, called pre-exposure prophylaxis (PrEP), has been shown to be highly effective. However, in spite of earning FDA approval, adoption of PrEP by MSM has been limited. The purpose of this study was to examine the experiences of a sample of 38 MSM who have adopted PrEP, focusing on communication with healthcare providers and social networks. In-depth interviews were used to collect data. Findings revealed that stigmatization by healthcare providers as well as stigmatization by other MSM was a relatively common experience for participants...
October 19, 2017: Health Communication
https://www.readbyqxmd.com/read/29047422/mycoplasma-genitalium-infection-in-adults-reporting-sexual-contact-with-infected-partners-australia-2008-2016
#11
Josephine B Slifirski, Lenka A Vodstrcil, Christopher K Fairley, Jason J Ong, Eric P F Chow, Marcus Y Chen, Timothy R H Read, Catriona S Bradshaw
Data on the likelihood of Mycoplasma genitalium infection in sexual contacts, particularly for men who have sex with men (MSM), are needed to form an evidence base for guidelines. We conducted a cross-sectional analysis of patients attending a sexual health clinic in Melbourne, Victoria, Australia, during 2008-2016. We calculated the proportion of contacts with M. genitalium infection and determined factors associated with infection. Among those patients reporting sexual contact with an M. genitalium-infected person, 48...
November 2017: Emerging Infectious Diseases
https://www.readbyqxmd.com/read/29047021/the-influence-of-constructed-family-membership-on-hiv-risk-behaviors-among-gay-bisexual-and-other-men-who-have-sex-with-men-in-new-orleans
#12
Meagan C Zarwell, William T Robinson
Gay, bisexual, and other men who have sex with men (MSM) represent more new HIV infections than all other at-risk populations. Many young black MSM belong to constructed families (i.e., the house ball community, gay families, and pageant families) which are often organized in a family structure with members referred to as parents and children. Many constructed families are associated with a family surname which is informally adopted by members. In some cases, however, constructed families do not identify with a collective family name...
October 18, 2017: Journal of Urban Health: Bulletin of the New York Academy of Medicine
https://www.readbyqxmd.com/read/29046951/time-trends-in-colorectal-cancer-early-postoperative-mortality-a-french-25-year-population-based-study
#13
Sylvain Manfredi, Valérie Jooste, Caroline Gay, Jean Faivre, Antoine Drouillard, Anne-Marie Bouvier
BACKGROUND: Postoperative mortality after resection of colorectal cancer is an important issue. The aim of this study was to assess early postoperative mortality in a well-defined French population. METHODS: Data on 30- and 90-day postoperative mortality after resection for colorectal cancer were extracted from the digestive cancer registry of Burgundy. Time trends of postoperative mortality between 1989 and 2013 were described for the large population. Case-control studies (death within 30 or 90 days = cases, alive at 90 days = controls) focused on the association between postoperative mortality and surgical approach, obesity and other comorbidities over the last [2010-2013] period, using conditional logistic regressions...
October 19, 2017: International Journal of Colorectal Disease
https://www.readbyqxmd.com/read/29045707/the-social-determinants-of-lesbian-gay-bisexual-and-transgender-youth-suicidality-in-england-a-mixed-methods-study
#14
Elizabeth McDermott, Elizabeth Hughes, Victoria Rawlings
Background: Lesbian, gay, bisexual and transgender (LGBT) youth have a higher risk of suicidality and self-harm than heterosexual youth populations but little is known about the underlying mechanisms. We aimed to investigate the social determinants of this mental health inequality. Methods: A two-stage sequential mixed method study was conducted. Firstly, 29 semi-structured interviews with LGBT youth (aged 13-25 years old) were completed. Data was analysed thematically...
October 17, 2017: Journal of Public Health
https://www.readbyqxmd.com/read/29045604/increases-in-neisseria-gonorrhoeae-with-reduced-susceptibility-to-azithromycin-among-men-who-have-sex-with-men-msm-in-seattle-king-county-washington-2012-2016
#15
Lindley A Barbee, Olusegun O Soge, David A Katz, Julia C Dombrowski, King K Holmes, Matthew R Golden
Background: Antimicrobial-resistant Neisseria gonorrhea is a major public health threat. The CDC recommends that clinicians treat gonorrhea with ceftriaxone 250mg plus azithromycin 1g. Resistance to azithromycin could affect gonorrhea control efforts. Methods: We evaluated antimicrobial susceptibility profiles and clinical data of gonococcal isolates collected at the Public Health-Seattle & King County (PHSKC) STD Clinic from 2012-2016, focusing on 2014-2016. We compared cases with CDC azithromycin (AZM) alert value MIC (MIC ≥2 µg/mL) to those with AZM MIC ≤1 µg/mL, and evaluated clinical outcomes...
October 16, 2017: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/29044601/let-s-not-talk-about-sex
#16
Melanie Love, Barry A Farber
This article uses both a case illustration and data from a large-scale survey of outpatient clients (N = 798) to understand the client's perspective about avoiding or being dishonest with his or her therapist about sexual topics. The case study, of a gay young man working with a heterosexual female therapist, explores this client's experience of what happens when it feels impossible to be forthcoming about sex and sexuality. Based on the findings of our study, we note clients' motives for avoiding these intimate yet important areas (e...
November 2017: Journal of Clinical Psychology
https://www.readbyqxmd.com/read/29044294/serum-levels-of-anti-pon1-and-anti-hdl-antibodies-as-potential-biomarkers-of-premature-atherosclerosis-in-systemic-lupus-erythematosus
#17
Patricia López, Javier Rodríguez-Carrio, Aleida Martínez-Zapico, Ángel I Pérez-Álvarez, Raquel López-Mejías, Lorena Benavente, Lourdes Mozo Mozo, Luis Caminal-Montero, Miguel A González-Gay, Ana Suárez
The present study aimed to evaluate the possible role of immunoglobulin G (IgG) antibodies against high-density lipoproteins (HDL) and paraoxonase 1 (PON1) as possible biomarkers of cardiovascular disease (CVD) in systemic lupus erythematosus (SLE). To this end, levels of these autoantibodies, PON1 activity and total antioxidant capacity were quantified in serum samples from 198 SLE patients, 100 healthy controls (HC) and 42 non-autoimmune individuals with traditional cardiovascular risk factors. PON1 rs662 polymorphism was analysed in a subgroup of patients and controls...
October 10, 2017: Thrombosis and Haemostasis
https://www.readbyqxmd.com/read/29043852/beliefs-about-others-perceptions-gender-typicality-scale-development-and-relationships-to-gender-nonconformity-sexual-orientation-and-well-being
#18
Laura Green, Katharine A Rimes, Qazi Rahman
The purpose of this study was to develop a measure of "other-perceived" gender typicality and test its relationship with gender nonconformity, sexual orientation, and psychological distress. Data on these variables were collected from 632 participants (142 heterosexual men, 77 gay men, 50 bisexual men, 174 heterosexual women, 85 lesbian women, and 104 bisexual women). We designed a Beliefs About Others' Perceptions-Gender Typicality (BOP-GT) scale on which participants reported how masculine or feminine they thought other people perceived their gendered behavior, interests, appearance, and activities...
October 18, 2017: Journal of Sex Research
https://www.readbyqxmd.com/read/29043846/-gay-equals-white-racial-ethnic-and-sexual-identities-and-attitudes-toward-lgbt-individuals-among-college-students-at-a-bible-belt-university
#19
Meredith G F Worthen
While past research has certainly explored a variety of correlates of attitudes toward lesbian, gay, bisexual, and transgender (LGBT) individuals, the current study is among the first in an emerging line of inquiry that examines attitudes toward each of these groups separately utilizing an intersectional framework with special attention to racial, ethnic, and sexual identities. Using a college sample of students from the Bible Belt of the United States (N = 1,940), I investigated the roles of racial and ethnic identities (Caucasian/White, African American/Black, Asian/Pacific Islander, Native American/Alaskan Native, other race, and Hispanic/Latinx), religiosity, patriarchal gender norms, parental perspectives, and the intersections among these identities and experiences as they relate to attitudes toward LGBT individuals among heterosexual (n = 1,551) and LGB respondents (n = 389)...
October 18, 2017: Journal of Sex Research
https://www.readbyqxmd.com/read/29043824/ferrofluid-based-droplet-interface-bilayer-networks
#20
Michelle Makhoul-Mansour, Wujun Zhao, Nicole Gay, Colleen O'Connor, Joseph Najem, Leidong Mao, Eric C Freeman
Droplet interface bilayer (DIB) networks allow for the construction of stimuli-responsive, membrane-based materials. Traditionally used for studying cellular transport phenomena, the DIB technique has proven its practicality when creating structured droplet networks. These structures consist of aqueous compartments capable of exchanging their contents across membranous barriers in a regulated fashion via embedded biomolecules, thus approximating the activity of natural cellular systems. However, lipid bilayer networks are often static and incapable of any reconfiguration in their architecture...
October 18, 2017: Langmuir: the ACS Journal of Surfaces and Colloids
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