keyword
MENU ▼
Read by QxMD icon Read
search

colorectal peritoneal metastasis

keyword
https://www.readbyqxmd.com/read/29138597/characteristics-and-prognostic-factors-of-colorectal-mucinous-adenocarcinoma-with-signet-ring-cells
#1
Xiangquan Kong, Xueqing Zhang, Yunxia Huang, Lirui Tang, Qingqin Peng, Jinluan Li
Background: Colorectal signet ring cell (SRC) carcinoma occurs rarely with a poor prognosis. The present study assessed the prognostic factors and predictive value of SRC ratio in colorectal mucinous adenocarcinoma (MAC) with SRCs (MAC-SRC). Patients and methods: A total of 95 consecutive colorectal MAC-SRC patients, confirmed pathologically from February 1987 to December 2015, were analyzed retrospectively in our institute. Clinical characteristics, pathological grade, TNM staging, and SRC ratio were assessed to identify the prognostic factors related to progression-free survival (PFS) and overall survival (OS)...
2017: Cancer Management and Research
https://www.readbyqxmd.com/read/29063295/long-term-outcomes-after-r0-resection-of-synchronous-peritoneal-metastasis-from-colorectal-cancer-without-cytoreductive-surgery-or-hyperthermic-intraperitoneal-chemotherapy
#2
Dai Shida, Shunsuke Tsukamoto, Hiroki Ochiai, Yukihide Kanemitsu
BACKGROUND: The National Comprehensive Cancer Network (NCCN) guidelines for colon cancer recently added the following footnote regarding the therapeutic strategy for peritoneal metastases: "If R0 resection can be achieved, surgical resection of isolated peritoneal disease may be considered at experienced centers." This study investigated the efficacy of R0 resection of peritoneal metastasis from colorectal cancer without cytoreductive surgery or hyperthermic intraperitoneal chemotherapy (HIPEC)...
October 23, 2017: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/29046790/intraluminal-rectal-cancer-metastasis-to-the-small-bowel-an-extremely-rare-case-report
#3
Paraskevas Stamopoulos, Nikolaos Machairas, Stylianos Kykalos, Afrodite Nonni, Gregory Kouraklis, Georgios C Sotiropoulos
Prolonged survival in patients suffering from colorectal cancer (CRC) may lead to the emergence of rare metastatic sites that are not well-documented in the literature. We herein describe a very rare case of an intraluminal small intestinal metastasis in a patient with previously resected CRC. A 71-year-old Caucasian male patient with a history of rectosigmoid junction cancer was initially treated with anterior resection. The tumor was classified as pT3pN0 (0/26) M0, stage II. Eighteen months after the primary surgery, local recurrence was detected in the presacral region, and the patient received combined image-guided radiotherapy and chemotherapy...
October 2017: Molecular and Clinical Oncology
https://www.readbyqxmd.com/read/29037218/clinicopathologic-features-and-treatment-efficacy-of-chinese-patients-with-braf-mutated-metastatic-colorectal-cancer-a-retrospective-observational-study
#4
Xicheng Wang, Qing Wei, Jing Gao, Jian Li, Jie Li, Jifang Gong, Yanyan Li, Lin Shen
BACKGROUND: The prognostic role of the V600E mutation of v-raf murine sarcoma viral oncogene homolog B1 (BRAF) in metastatic colorectal cancer (mCRC) is well established, but the therapeutic regimen targeting this disease is lacking. This study aimed to analyze the clinicopathologic features of and treatment efficacy of commonly used regimens on BRAF-mutated mCRCs. METHODS: We collected and reviewed the medical records of mCRC patients treated at Peking University Cancer Hospital & Institute (Beijing, China) between July 2011 and July 2016...
October 16, 2017: Chinese Journal of Cancer
https://www.readbyqxmd.com/read/28956065/the-peritoneal-soil-for-a-cancerous-seed-a-comprehensive-review-of-the-pathogenesis-of-intraperitoneal-cancer-metastases
#5
REVIEW
Justyna Mikuła-Pietrasik, Paweł Uruski, Andrzej Tykarski, Krzysztof Książek
Various types of tumors, particularly those originating from the ovary and gastrointestinal tract, display a strong predilection for the peritoneal cavity as the site of metastasis. The intraperitoneal spread of a malignancy is orchestrated by a reciprocal interplay between invading cancer cells and resident normal peritoneal cells. In this review, we address the current state-of-art regarding colonization of the peritoneal cavity by ovarian, colorectal, pancreatic, and gastric tumors. Particular attention is paid to the pro-tumoral role of various kinds of peritoneal cells, including mesothelial cells, fibroblasts, adipocytes, macrophages, the vascular endothelium, and hospicells...
September 27, 2017: Cellular and Molecular Life Sciences: CMLS
https://www.readbyqxmd.com/read/28954998/solitary-distant-peritoneal-metastasis-of-cecal-cancer-after-laparoscopic-colectomy-a-case-report
#6
Akira Ouchi, Koji Komori, Kenya Kimura, Takashi Kinoshita, Seiji Ito, Tetsuya Abe, Yoshiki Senda, Kazunari Misawa, Yuichi Ito, Norihisa Uemura, Seiji Natsume, Jiro Kawakami, Yasuhiro Shimizu
A 77-year-old Japanese female underwent laparoscopic ileocecal resection and lymph node dissection for cecal cancer by a previous doctor. Two years and 9 months after previous operation, contrast-enhanced computed tomography and magnetic resonance imaging with gadolinium ethoxybenzyl-L-diethylenetriamine pentaacetic acid revealed an intraperitoneal tumor at the right subphrenic fossa. 18F-fluorodeoxyglucose position emission tomography showed fluorodeoxyglucose accumulation in the tumor, and we suspected the tumor to be solitary distant peritoneal metastasis of the previous cecal cancer to the right diaphragm...
2017: Journal of Medical Investigation: JMI
https://www.readbyqxmd.com/read/28891847/prognostic-significance-of-peritoneal-metastasis-in-stage-iv-colorectal-cancer-patients-with-r0-resection-a-multicenter-retrospective-study
#7
MULTICENTER STUDY
Keiichi Arakawa, Kazushige Kawai, Soichiro Ishihara, Keisuke Hata, Hiroaki Nozawa, Koji Oba, Kenichi Sugihara, Toshiaki Watanabe
BACKGROUND: Stage IV colorectal cancer encompasses various clinical conditions. The differences in prognosis after surgery between different metastatic organs have not been fully investigated. OBJECTIVE: This study aimed to assess prognostic significance in peritoneal metastasis in R0 resected stage IV colorectal cancer. DESIGN: We conducted a multicenter retrospective study of patients with R0 resected stage IV colorectal cancer; they were categorized into 3 groups according to the number and location of metastatic organs, including single-organ metastasis in the peritoneum, single-organ metastasis at sites except the peritoneum, and multiple-organ metastases...
October 2017: Diseases of the Colon and Rectum
https://www.readbyqxmd.com/read/28874886/in-search-for-optimal-targets-for-intraoperative-fluorescence-imaging-of-peritoneal-metastasis-from-colorectal-cancer
#8
Charlotte Es Hoogstins, Benjamin Weixler, Leonora Sf Boogerd, Diederik J Hoppener, Hendrica Ajm Prevoo, Cornelis Fm Sier, Jacobus Wa Burger, Cornelis Verhoef, Shadvhi Bhairosingh, Arantza Farina Sarasqueta, Jacobus Burggraaf, Alexander L Vahrmeijer
Peritoneal metastasis (PM) occurs in about 10% of patients with colorectal cancer (CRC). Fluorescence imaging can enhance contrast between cancerous and benign tissue, enabling the surgeon to clearly visualize PM during cytoreductive surgery. This study assessed the suitability of different biomarkers as potential targets for tumor-targeted imaging of PM of CRC. Tissue samples from primary tumor and PM from patients with CRC were obtained from the pathology archives and immunohistochemical stainings were performed...
2017: Biomarkers in Cancer
https://www.readbyqxmd.com/read/28828897/preoperative-nutritional-risk-assessment-in-patients-undergoing-cytoreductive-surgery-plus-hyperthermic-intraperitoneal-chemotherapy-for-colorectal-carcinomatosis
#9
Nathan Banaste, Pascal Rousset, Frederic Mercier, Clémentine Rieussec, Pierre-Jean Valette, Olivier Glehen, Guillaume Passot
BACKGROUND: Malnutrition is associated with increased postoperative morbidity in colorectal surgery. This study aimed to determine if preoperative nutritional markers could predict postoperative outcomes for patients undergoing cytoreductive surgery with hyperthermic intraperitoneal chemotherapy (CRS-HIPEC) for peritoneal metastasis (PM) of colorectal origin. METHODS: All patients who underwent a complete CRS-HIPEC for colorectal PM between January 2009 and December 2014 were evaluated...
September 3, 2017: International Journal of Hyperthermia
https://www.readbyqxmd.com/read/28789931/clinical-analysis-of-primary-colorectal-signet-ring-cell-carcinoma
#10
REVIEW
ZhengZi Liang, DengGuo Yan, GuoSheng Li, HaiYu Cheng
The objective of the study was to investigate the clinicopathological features of primary colorectal signet-ring cell carcinoma. We retrospectively analyzed the clinical and survival data of 37 patients with primary colorectal signet-ring cell carcinoma. The mean survival time of patients in stage II, III, and IV were estimated using Student t test and the cumulative survival rates were estimated according to the method of Kaplan-Meier. The significance of the differences in survival rates were calculated using the log rank test...
July 8, 2017: Clinical Colorectal Cancer
https://www.readbyqxmd.com/read/28772202/the-role-of-surgical-excision-for-the-krukenberg-tumour-a-case-report
#11
David Lam, Eugene Ong
INTRODUCTION: Krukenberg tumour (KT), which represents carcinoma in the ovary, is an uncommon manifestation of metastatic colorectal cancer. It is associated with poor prognosis and a high incidence of peritoneal metastatic disease. PRESENTATION OF CASE: The authors present a case of a 51-year-old female who had a symptomatic, metachronous right ovarian KT diagnosed 12 months after her initial resection. Surgery was performed to excise the 23cm tumour as well as the contralateral ovary and isolated peritoneal disease, with an R0 resection achieved...
2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/28764712/sclerosing-mesenteritis-mimicking-metachronous-peritoneal-metastases-from-descending-colon-adenocarcinoma
#12
Toshifumi Watanabe, Shiro Terai, Tomoya Tsukada, Masaki Takeshita, Koshi Matsui, Koji Amaya, Masahide Kaji, Kiichi Maeda, Koichi Shimizu, Junko Saito, Kentaro Mochizuki, Akio Uchiyama
BACKGROUND: Sclerosing mesenteritis is a non-neoplastic inflammatory disease that occurs in the bowel mesentery. Distinguishing sclerosing mesenteritis from neoplasms may be difficult because of the clinical and radiographic similarities between the two disease entities. CASE PRESENTATION: We report a case of sclerosing mesenteritis mimicking peritoneal metastases of colorectal carcinoma. A 73-year-old man with stage II descending colon adenocarcinoma with poor prognostic features was found to have developed left lower abdominal quadrant masses on computed tomography (CT) 9 months after undergoing radical surgery...
August 1, 2017: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28664645/treatment-of-peritoneal-carcinomatosis-with-hyperthermic-intraperitoneal-chemotherapy-in-colorectal-cancer
#13
REVIEW
Corina Behrenbruch, Frédéric Hollande, Benjamin Thomson, Michael Michael, Satish K Warrier, Craig Lynch, Alexander Heriot
The peritoneum is the second most common site of metastasis after the liver and the only site of metastatic disease in approximately 25% of patients with colorectal cancer (CRC). In the past, peritoneal carcinomatosis in CRC was thought to be equivalent to distant metastasis; however, the transcoelomic spread of malignant cells is an acknowledged alternative pathway. Metastasectomy with curative intent is well accepted in patients with liver metastasis in CRC despite the paucity of randomized trials. Therefore, there is rationale for local treatment with peritonectomy to eliminate macroscopic disease, followed by hyperthermic intraperitoneal chemotherapy to destroy any residual free tumour cells within the peritoneal cavity...
September 2017: ANZ Journal of Surgery
https://www.readbyqxmd.com/read/28628012/curative-treatment-of-colorectal-cancer-solitary-metastasis-to-liver-subcapsule-by-percutaneous-us-guided-radiofrequency-ablation-using-hydrodissection-case-report
#14
N Paksashvili, T Ninikashvili, T Azrumelashvili, M Mizandari
Case report presents the successful treatment of solitary liver metastasis in a patient with resected colon cancer. A 39-year-old male underwent left hemicolectomy with colostomy formation followed by chemotherapy for a moderately differentiated adenocarcinoma of the colon. Two years later, a liver metastatic lesion was detected. Patient received chemotherapy; the mass remained stable in size, measuring up to 3 cm in diameter. Low-invasive percutaneous curative treatment by Radiofrequency ablation was conducted using hydrodissection by dielectric fluid intraperitoneal introduction for hydrodissection...
May 2017: Georgian Medical News
https://www.readbyqxmd.com/read/28626261/a-case-of-metachronous-left-ovarian-metastasis-8-years-after-surgery-for-cecal-cancer-and-right-ovarian-metastasis-report-of-a-case
#15
Itaru Shigeyoshi, Koji Komori, Takashi Kinoshita, Taihei Oshiro, Seiji Ito, Tetsuya Abe, Yoshiki Senda, Kazunari Misawa, Yuichi Ito, Norihisa Uemura, Seiji Natsume, Jiro Kawakami, Akira Ouchi, Masayuki Tsutsuyama, Takahiro Hosoi, Tomoyuki Akazawa, Daisuke Hayashi, Hideharu Tanaka, Yasushi Yatabe, Yasuhiro Shimizu
Metachronous ovarian metastasis of colorectal adenocarcinoma is mostly identified within 3 years. Here we present a case of a 64-year-old woman with cecal cancer who underwent right oophorectomy for ovarian metastasis. Imaging was performed because of abdominal bloating; it detected a swollen right ovary with ascites. On laparotomy, a right ovarian tumor and cecal cancer were identified. After right oophorectomy, a diagnosis of unilateral ovarian metastasis from colon cancer was made. One month later, right hemicolectomy was performed...
February 2017: Nagoya Journal of Medical Science
https://www.readbyqxmd.com/read/28594718/risk-of-ovarian-involvement-in-advanced-colorectal-or-appendiceal-tumors-involving-the-peritoneum
#16
Akash M Mehta, Mark B Bignell, Sue Alves, Sanjeev P Dayal, Faheez Mohamed, Tom D Cecil, Brendan J Moran
BACKGROUND: Ovarian metastases of GI tumors grow rapidly and are relatively resistant to systemic chemotherapy. They may be unilateral or bilateral and macroscopic or occult. The risk of macroscopic ovarian involvement or occult involvement of macroscopically normal ovaries is unquantified. OBJECTIVE: This study aims to quantify the risks of ovarian involvement in patients with peritoneal malignancy undergoing cytoreductive surgery with hyperthermic intraperitoneal chemotherapy...
July 2017: Diseases of the Colon and Rectum
https://www.readbyqxmd.com/read/28567071/associating-liver-partition-and-portal-vein-ligation-for-staged-hepatectomy-a-surgical-technique-for-liver-resections
#17
Behnam Sanei, Saba Sheikhbahaei, Mohammad Hossein Sanei, Amin Bahreini, Hamid Reza Jafari
BACKGROUND: Associating liver partition and portal vein ligation for staged hepatectomy (ALPPS) is a novel surgical technique liver resection in traditionally nonresectable primary intrahepatic tumors or colorectal liver metastases. MATERIALS AND METHODS: From June 2013 to March 2014, patients with primary tumor of liver or colorectal tumors with liver metastasis were selected to evaluate whether they met the initial criteria for ALPPS procedure. RESULTS: Nine patients enrolled in the study with primary diagnoses of colon and rectosigmoid cancer, carcinoid tumor, gastrointestinal stromal tumor of small intestine, hepatocellular carcinoma, and pancreatic neuroendocrine tumor (PNET)...
2017: Journal of Research in Medical Sciences: the Official Journal of Isfahan University of Medical Sciences
https://www.readbyqxmd.com/read/28538365/cytoreductive-surgery-with-hyperthermic-intraperitoneal-chemotherapy-for-appendiceal-and-colorectal-cancer-with-peritoneal-carcinomatosis-clinical-outcomes-at-2-tertiary-referral-centers-in-korea
#18
MULTICENTER STUDY
Eun Jung Park, Seung Hyuk Baik, Hyuk Hur, Byung Soh Min, Jeonghyun Kang, Yun Dae Han, Min Soo Cho, Kang Young Lee, Nam Kyu Kim
Cytoreductive surgery (CRS) with hyperthermic intraperitoneal chemotherapy (HIPEC) is regarded as effective surgical treatments in patients with peritoneal metastasis. This study aimed to evaluate the clinical outcomes of CRS and HIPEC in patients with appendiceal or colorectal cancer with peritoneal carcinomatosis.A total of 66 patients who underwent CRS with HIPEC for appendiceal or colorectal cancer with peritoneal metastasis at 2 tertiary referral centers in Korea were evaluated between July 2014 and March 2016...
May 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28535418/a-study-of-peritoneal-metastatic-xenograft-model-of-colorectal-cancer-in-the-treatment-of-hyperthermic-intraperitoneal-chemotherapy-with-raltitrexed
#19
Cen Qiu, Yueqi Li, Xin Liang, Yingxue Qi, Yiyang Chen, Xianke Meng, Hongtu Zheng, Ye Xu, Sanjun Cai, Guoxiang Cai, Jianwen Liu
Peritoneal metastasis of colorectal cancer is one of the most incident and fateful diseases among relapse cases. It shows a certain resistance to systemic chemotherapy. The perfusion system in clinic is complex and hard to be used in fundamental researches. This study aims at evaluating the effect of an improved hyperthermic intraperitoneal chemotherapy with Raltitrexed used in tumor-bearing mice with peritoneal metastatic colorectal carcinoma. The results showed that no severe adverse effect was observed. All control animals developed extensive peritoneal and mesenteric metastatic nodes...
August 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/28516306/peritoneal-metastasis-from-pancreatic-cancer-treated-with-pressurized-intraperitoneal-aerosol-chemotherapy-pipac
#20
Martin Graversen, Sönke Detlefsen, Jon Kroll Bjerregaard, Per Pfeiffer, Michael Bau Mortensen
Patients with peritoneal metastasis (PM) from pancreatic cancer have a short life expectancy. Systemic combination chemotherapy leads to a median overall survival of 7-8 months. Pressurized IntraPeritoneal Aerosol Chemotherapy (PIPAC) is a treatment alternative, where studies in patients with PM from ovarian, gastric and colorectal cancer show a high safety profile and interesting results. This case study report data on the PIPAC treatment in patients with PM from pancreatic cancer. In a standard laparoscopy, chemotherapeutics (cisplatin and doxorubicin) are nebulized within the peritoneal cavity...
May 17, 2017: Clinical & Experimental Metastasis
keyword
keyword
53496
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"