keyword
MENU ▼
Read by QxMD icon Read
search

Yolk sac

keyword
https://www.readbyqxmd.com/read/28102527/teratoma-of-the-sellar-region-a-case-report
#1
Wolfgang Saeger, Azadeh Ebrahimi, Rudi Beschorner, Hildegard Spital, Jürgen Honegger, Waldemar Wilczak
The case report describes a teratoma of the sellar region with a gland forming and an immature, relatively clear undifferentiated component without signs of anaplasia. Both components express TTF-1 indicating their presumable origin in the neurohypophysis as part of the circumventricular organs. The differential diagnosis includes pituitary adenoma and spindle cell oncocytoma with inclusion of Rathke's cleft cyst, pituitary blastoma, yolk sac tumor, and other germ cell tumors. The prognosis is the same as in the immature teratomas in the gonads, specifically unclear...
January 19, 2017: Endocrine Pathology
https://www.readbyqxmd.com/read/28088501/a-review-of-reproductive-and-developmental-toxicity-of-silver-nanoparticles-in-laboratory-animals
#2
REVIEW
Makoto Ema, Hirokazu Okuda, Masashi Gamo, Kazumasa Honda
We summarized significant effects reported in the literature on the reproductive and developmental toxicity of silver nanoparticles (AgNPs) in laboratory animals. AgNPs showed testicular/sperm toxicity in males and ovarian and embryonic toxicity in females. Maternal injection of AgNPs delayed physical development and impaired cognitive behavior in offspring. Ag was accumulated in the testes after administration of AgNPs. AgNPs were identified in the visceral yolk sac after administration during early gestation in mice...
January 11, 2017: Reproductive Toxicology
https://www.readbyqxmd.com/read/28074839/high-precision-non-invasive-anti-microvascular-approach-via-concurrent-ultrasound-and-laser-irradiation
#3
Zizhong Hu, Haonan Zhang, Aghapi Mordovanakis, Yannis M Paulus, Qinghuai Liu, Xueding Wang, Xinmai Yang
Antivascular therapy represents a proven strategy to treat angiogenesis. By applying synchronized ultrasound bursts and nanosecond laser irradiation, we developed a novel, selective, non-invasive, localized antivascular method, termed photo-mediated ultrasound therapy (PUT). PUT takes advantage of the high native optical contrast among biological tissues and can treat microvessels without causing collateral damage to the surrounding tissue. In a chicken yolk sac membrane model, under the same ultrasound parameters (1 MHz at 0...
January 11, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28070053/-a-case-report-for-primary-yolk-sac-tumor-of-endometrium
#4
Yuan Hu, Fei Zeng, Min Xue, Songshu Xiao
A case of primary yolk sac tumor of endometrium was retrospectively analyzed and relevant literature was systematically reviewed. We found that the primary yolk sac tumor of endometrium showed low incidence rate and was clinically characterized by abnormal vaginal bleeding, intrauterine lesions and significantly elevated alpha-fetoprotein (AFP) level. The final diagnosis should be confirmed by pathological examination. There is no guideline for the treatment of primary yolk sac tumor of endometrium due to its rareness...
December 28, 2016: Zhong Nan da Xue Xue Bao. Yi Xue Ban, Journal of Central South University. Medical Sciences
https://www.readbyqxmd.com/read/28065741/essential-roles-for-cdx-in-murine-primitive-hematopoiesis
#5
Travis Brooke-Bisschop, Joanne G A Savory, Tanya Foley, Randy Ringuette, David Lohnes
The Cdx transcription factors play essential roles in primitive hematopoiesis in the zebrafish where they exert their effects, in part, through regulation of hox genes. Defects in hematopoiesis have also been reported in Cdx mutant murine embryonic stem cell models, however, to date no mouse model reflecting the zebrafish Cdx mutant hematopoietic phenotype has been described. This is likely due, in part, to functional redundancy among Cdx members and the early lethality of Cdx2 null mutants. To circumvent these limitations, we used Cre-mediated conditional deletion to assess the impact of concomitant loss of Cdx1 and Cdx2 on murine primitive hematopoiesis...
January 5, 2017: Developmental Biology
https://www.readbyqxmd.com/read/28062667/smn-deficiency-negatively-impacts-red-pulp-macrophages-and-spleen-development-in-mouse-models-of-spinal-muscular-atrophy
#6
Marie-Therese Khairallah, Jacob Astroski, Sarah K Custer, Elliot J Androphy, Craig L Franklin, Christian L Lorson
Spinal muscular atrophy (SMA) is a progressive neurodegenerative disease that is the leading genetic cause of infantile death. It is caused by severe deficiency of the ubiquitously expressed Survival Motor Neuron (SMN) protein. SMA is characterized by α-lower motor neuron loss and muscle atrophy, however, there is a growing list of tissues impacted by SMN deficiency beyond motor neurons. The non-neuronal defects are observed in the most severe Type I SMA patients and most of the widely used SMA mouse models, however, as effective therapeutics are developed, it is unclear whether additional symptoms will be uncovered in longer lived patients...
January 5, 2017: Human Molecular Genetics
https://www.readbyqxmd.com/read/28058004/testicular-cancer-in-down-syndrome-with-spinal-cord-metastases
#7
Turky Almouhissen, Hattan Badr, Bassam AlMatrafi, Noor Alessa, Anmar Nassir
A 22-year-old male patient with Down syndrome was referred to our hospital with a vast left testicular mass. He underwent a left radical inguinal orchiectomy, and a histopathological examination of the mass showed a yolk sac tumor invading the epididymis. The patient was discharged in a satisfactory condition. Sixteen days later, the patient presented again complaining of lower limb weakness. Magnetic resonance imaging of the spine showed metastatic lesions compressing the dorsal spine, and he underwent emergency surgical decompression...
October 2016: Urology Annals
https://www.readbyqxmd.com/read/28039901/living-donor-liver-transplantation-in-a-pediatric-patient-with-preexisting-yolk-sac-tumor
#8
Taiichi Wakiya, Yoshikazu Toyoki, Keinosuke Ishido, Daisuke Kudo, Norihisa Kimura, Shinji Tsutsumi, Tadashi Odagiri, Akiko Suto, Chiaki Uchida, Kenichi Hakamada
There is ongoing discussion regarding the indications and timing of LT for patients with a preexisting extrahepatic malignancy. We herein report a pediatric case that underwent LDLT after therapy for YST. The patient, a 13-year-old female with biliary atresia, had undergone portoenterostomy at 2 months of age. She developed a left ovarian tumor with a high serum alpha-fetoprotein concentration at 10 years of age. She underwent left oophorectomy and was diagnosed with ovarian YST (Stage I). After surgery, hepatopulmonary syndrome progressed gradually...
December 30, 2016: Pediatric Transplantation
https://www.readbyqxmd.com/read/28024118/maternal-fetal-cholesterol-transport-in-the-second-half-of-mouse-pregnancy-does-not-involve-lrp2
#9
Mathijs V Zwier, Maria E Baardman, Theo H van Dijk, Angelika Jurdzinski, Lambertus J Wisse, Vincent W Bloks, Rolf M F Berger, Marco C DeRuiter, Albert K Groen, Torsten Plösch
AIM: Lipoprotein related receptor protein type 2 (LRP2) is highly expressed on both yolk sac and placenta. Mutations in the corresponding gene are associated with severe birth defects in humans, known as Donnai-Barrow syndrome. We here characterized the contribution of LRP2 and maternal plasma cholesterol availability to maternal-fetal cholesterol transport and fetal cholesterol levels in utero in mice. METHODS: Lrp2(+/-) mice were mated heterozygously to yield fetuses of all 3 genotypes...
December 26, 2016: Acta Physiologica
https://www.readbyqxmd.com/read/28013088/risk-of-malignant-childhood-germ-cell-tumors-in-relation-to-demographic-gestational-and-perinatal-characteristics
#10
Clinton Hall, Beate Ritz, Myles Cockburn, Tom B Davidson, Julia E Heck
BACKGROUND: Childhood germ cell tumors (GCTs) are a rare assortment of neoplasms, with mostly unknown etiology, that are believed to originate very early in life. Few studies have examined risk factors by histologic subtype, despite evidence of different risk profiles. MATERIALS AND METHODS: In this population-based case-control study, 451 childhood malignant GCT cases ages 0-5 years were identified from the California Cancer Registry. Differentiating between common histologic subtypes, we identified 181 yolk sac tumors, 216 teratomas, and 54 rarer subtypes...
December 22, 2016: Cancer Epidemiology
https://www.readbyqxmd.com/read/28012457/identification-of-novel-genetic-markers-for-mouse-yolk-sac-cells-by-using-microarray-analyses
#11
Shinomi Yagi, Nobuyoshi Shiojiri
The mouse embryonic yolk sac consists of a visceral yolk sac (VYS) and parietal yolk sac (PYS), and may function as a materno-fetal exchange system for nutrients and wastes, and physical protector for the embryo/fetus. The present study was undertaken to characterize gene expression of the VYS and PYS endodermal cells, and to identify their novel genetic markers from microarray data. Apoa4, Lrp2, Fxyd2, Slc34a3 and Entpd2 were predominantly expressed in VYS epithelial cells. Gkn2 and Pga5 were selected as markers for PYS cells...
January 2017: Placenta
https://www.readbyqxmd.com/read/28003760/comparison-of-the-clinical-features-and-hematopoietic-stem-cell-transplantation-outcomes-of-mediastinal-malignant-germ-cell-tumors-with-nonmediastinal-extragonadal-placements
#12
Nesrin Ocal, Birol Yildiz, Nuri Karadurmus, Deniz Dogan, Sukru Ozaydin, Ramazan Ocal, Mustafa Ozturk, Fikret Arpaci, Hayati Bilgic
OBJECTIVE: Even though the primary mediastinal extragonadal germ cell tumors (EGCTs) are rare, they are noteworthy in the differential diagnosis of mediastinal masses. In this study, we aimed to identify the clinical features of mediastinal malignant GCTs and compare the results of hematopoietic stem cell transplantation between mediastinal and nonmediastinal malignant EGCTs. METHOD: Data of the patients with EGCT who were treated and underwent hematopoietic stem cell transplantation at our hospital between 1988 and 2015 were retrieved retrospectively...
2016: OncoTargets and Therapy
https://www.readbyqxmd.com/read/28003520/higher-temperature-exacerbates-the-impact-of-sediments-on-embryo-performances-in-a-salmonid
#13
Lisandrina Mari, Laura Garaud, Guillaume Evanno, Emilien Lasne
In a warming climate, higher temperatures are likely to modulate positively or negatively the effect of other environmental factors on biota, although such interactions are poorly documented. Here, we explore under controlled conditions the combined effects of two common stressors in freshwater ecosystems, higher temperature and sediment load, on the embryonic development of arctic charr (Salvelinus alpinus L.). In the warm treatment, embryos had a lower survival, a longer incubation period and a smaller body size with a bigger yolk sac volume...
December 2016: Biology Letters
https://www.readbyqxmd.com/read/28000905/teratomas-produced-from-human-pluripotent-stem-cells-xenografted-into-immunodeficient-mice-a-histopathology-atlas
#14
Ivan Damjanov, Peter W Andrews
This atlas illustrates the microscopic features of tumors produced from human pluripotent stem cells (hPSCs) xenografted into immunosuppressed mice, according to the generally accepted protocols for performing this teratoma assay of stem cell pluripotency. Microphotographs depict various hematoxylin and eosin (H&E) stained tissues derived from all three embryonic germ layers (ectoderm, mesoderm and endoderm). The appearance of persistent hPSC in teratomas is also described with special emphasis on the morphogenesis of embryoid bodies and yolk sac components surrounding them...
2016: International Journal of Developmental Biology
https://www.readbyqxmd.com/read/27995468/alpha-fetoprotein-producing-esophageal-adenocarcinoma-a-mimicker-of-hepatocellular-carcinoma
#15
Jeremy Wang, Wendy Liu, Keyur Parikh, Anthony Benjamin Post
Alpha-fetoprotein (AFP)-producing esophageal adenocarcinoma (EAC) is a rare occurrence. Elevation of serum AFP is commonly associated with hepatocellular carcinoma and yolk sac tumors, but rarely with esophageal carcinoma. Here, we report a rare case of AFP-producing EAC. A 51-year-old man presented with two weeks of acid reflux and a 35-lb weight loss. Laboratory data were notable for transaminitis and AFP was 2524 ng/mL. Computed tomography of the abdomen revealed abnormal thickening of the esophagus and multiple metastatic masses throughout the liver...
December 19, 2016: Clinical Journal of Gastroenterology
https://www.readbyqxmd.com/read/27991852/epithelial-magnesium-transport-by-trpm6-is-essential-for-prenatal-development-and-adult-survival
#16
Vladimir Chubanov, Silvia Ferioli, Annika Wisnowsky, David G Simmons, Christin Leitzinger, Claudia Einer, Wenke Jonas, Yuriy Shymkiv, Harald Bartsch, Attila Braun, Banu Akdogan, Lorenz Mittermeier, Ludmila Sytik, Friedrich Torben, Vindi Jurinovic, Emiel Pc van der Vorst, Christian Weber, Önder A Yildirim, Karl Sotlar, Annette Schürmann, Susanna Zierler, Hans Zischka, Alexey G Ryazanov, Thomas Gudermann
Mg(2+) regulates many physiological processes and signalling pathways. However, little is known about the mechanisms underlying the organismal balance of Mg(2+). Capitalizing on a set of newly generated mouse models, we provide an integrated mechanistic model of the regulation of organismal Mg(2+) balance during prenatal development and in adult mice by the ion channel TRPM6. We show that TRPM6 activity in the placenta and yolk sac is essential for embryonic development. In adult mice, TRPM6 is required in the intestine to maintain organismal Mg(2+) balance, but is dispensable in the kidney...
December 19, 2016: ELife
https://www.readbyqxmd.com/read/27965271/different-mechanisms-of-na-uptake-and-ammonia-excretion-by-the-gill-and-yolk-sac-epithelium-of-early-life-stage-rainbow-trout
#17
Alex M Zimmer, Jonathan M Wilson, Patricia A Wright, Junya Hiroi, Chris M Wood
In rainbow trout, the dominant site of Na(+) uptake (J(Na)in) and ammonia excretion (Jamm) shifts from the skin to the gills over development. Post-hatch (PH; 7 days post-hatch) larvae utilize the yolk sac skin for physiological exchange, whereas by complete yolk sac absorption (CYA; 30 days post-hatch), the gill is the dominant site. At the gills, J(Na)in and Jamm occur via loose Na(+)/NH4(+) exchange, but this exchange has not been examined in the skin of larval trout. Based on previous work, we hypothesized that, contrary to the gill model, J(Na)in by the yolk sac skin of PH trout occurs independently of Jamm Following a 12-h exposure to high environmental ammonia (HEA; 0...
December 13, 2016: Journal of Experimental Biology
https://www.readbyqxmd.com/read/27959583/unusual-presentations-of-gynecologic-tumors-extragonadal-yolk-sac-tumor-of-the-vulva
#18
Elizabeth D Euscher
Extragonadal germ cell tumors are uncommon, and although they morphologically resemble their gonadal counterparts, unexpected gonadal presentation increases the potential for erroneous diagnoses. Yolk sac tumor is a malignant germ cell tumor characterized by an extraembryonic yolk sac line of differentiation, and relative to other germ cell tumors, is characterized by varied and diverse histologic patterns. When occurring outside of typical age parameters or in extragonadal locations, the histologic variability of yolk sac tumor and its tendency to mimic somatic tumors pose diagnostic challenges...
December 13, 2016: Archives of Pathology & Laboratory Medicine
https://www.readbyqxmd.com/read/27957372/nephroblastoma-arising-from-primary-testicular-germ-cell-tumor-a-case-report-and-literature-review
#19
Houda Alatassi, Brittany E O'Bryan, Jamie C Messer, Zhenglong Wang
Adult extrarenal nephroblastoma is a very rare tumor. Nephroblastoma arising from primary testicular germ cell tumor is exceedingly rare. To our knowledge, only three cases have been reported in the English literature. We report a case of a 19-year-old man who presented with a large right testicle. Image studies showed a large retroperitoneal mass along with liver and lung metastases. Orchiectomy demonstrated a mixed germ cell tumor composed of yolk sac tumor, embryonal carcinoma, and mature and immature teratoma with a significant portion of nephroblastoma...
2016: Case Reports in Pathology
https://www.readbyqxmd.com/read/27940477/distinct-regulatory-networks-control-the-development-of-macrophages-of-different-origins-in-zebrafish
#20
Tao Yu, Weilin Guo, Ye Tian, Jin Xu, Jiahao Chen, Li Li, Zilong Wen
Macrophages are key components of the innate immune system and play pivotal roles in immune response, organ development and tissue homeostasis. Studies in mice and zebrafish have shown that tissue-resident macrophages derived from different hematopoietic origins manifest distinct developmental kinetics and colonization potential. Yet, the genetic programs controlling the development of macrophages of different origins remain incompletely defined. In this study, we utilize zebrafish, where tissue-resident macrophages arise from the rostral blood island (RBI) and ventral wall of dorsal aorta (VDA), the zebrafish hematopoietic tissue equivalents to the mouse yolk sac (YS) and aorta-gonad-mesonephros (AGM) for myelopoiesis, to address this issue...
December 9, 2016: Blood
keyword
keyword
53492
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"