Read by QxMD icon Read


Harald Kramer, Perry J Pickhardt, Mark A Kliewer, Diego Hernando, Guang-Hong Chen, James A Zagzebski, Scott B Reeder
OBJECTIVE: The purpose of this study was to prospectively evaluate the accuracy of proton-density fat-fraction, single- and dual-energy CT (SECT and DECT), gray-scale ultrasound (US), and US shear-wave elastography (US-SWE) in the quantification of hepatic steatosis with MR spectroscopy (MRS) as the reference standard. SUBJECTS AND METHODS: Fifty adults who did not have symptoms (23 men, 27 women; mean age, 57 ± 5 years; body mass index, 27 ± 5) underwent liver imaging with un-enhanced SECT, DECT, gray-scale US, US-SWE, proton-density fat-fraction MRI, and MRS for this prospective trial...
October 11, 2016: AJR. American Journal of Roentgenology
Lotte E J R Schyns, Isabel P Almeida, Stefan J van Hoof, Benedicte Descamps, Christian Vanhove, Guillaume Landry, Patrick V Granton, Frank Verhaegen
OBJECTIVES: The aim of this work was to investigate if quantitative dual energy CT (DECT) imaging is feasible for small animal irradiators with an integrated cone beam CT (CBCT) system. METHODS: The optimal imaging protocols were determined by analyzing different energy combinations and dose levels. The influence of beam hardening effects and the performance of a beam hardening correction were investigated. In addition, two systems from different manufacturers were compared in terms of errors in the extracted effective atomic numbers ([Formula: see text]) and relative electron densities ([Formula: see text]) for phantom inserts with known elemental compositions and relative electron densities...
September 28, 2016: British Journal of Radiology
Taiki Magome, Jerry Froelich, Yutaka Takahashi, Luke Arentsen, Shernan Holtan, Michael R Verneris, Keenan Brown, Akihiro Haga, Keiichi Nakagawa, Jennifer L Holter Chakrabarty, Sebastian Giebel, Jeffrey Wong, Kathryn Dusenbery, Guy Storme, Susanta K Hui
PURPOSE: To develop an imaging method to characterize and map marrow composition in the entire skeletal system, and to simulate differential targeted marrow irradiation based on marrow composition. METHODS AND MATERIALS: Whole-body dual energy computed tomography (DECT) images of cadavers and leukemia patients were acquired, segmented to separate bone marrow components, namely, bone, red marrow (RM), and yellow marrow (YM). DECT-derived marrow fat fraction was validated using histology of lumbar vertebrae obtained from cadavers...
November 1, 2016: International Journal of Radiation Oncology, Biology, Physics
Vidhya Kumar, James K Min, Xin He, Subha V Raman
Dual-energy computed tomography (DECT) improves material and tissue characterization compared with single-energy CT; we sought to validate coronary calcium quantification in advancing cardiovascular DECT. In an anthropomorphic phantom, agreement between measurements was excellent, and Bland-Altman analysis demonstrated minimal bias. Compared with the known calcium mass for each phantom, calcium mass by DECT was highly accurate. Noncontrast DECT yields accurate calcium measures and warrants consideration in cardiac protocols for additional tissue characterizations...
September 27, 2016: Journal of Computer Assisted Tomography
K Hellbach, A Sterzik, W Sommer, M Karpitschka, N Hummel, J Casuscelli, M Ingrisch, M Schlemmer, A Graser, Michael Staehler
OBJECTIVES: To evaluate the potential role of dual energy CT (DECT) to visualize antiangiogenic treatment effects in patients with metastatic renal cell cancer (mRCC) while treated with tyrosine-kinase inhibitors (TKI). METHODS: 26 patients with mRCC underwent baseline and follow-up single-phase abdominal contrast enhanced DECT scans. Scans were performed immediately before and 10 weeks after start of treatment with TKI. Virtual non-enhanced (VNE) and colour coded iodine images were generated...
September 27, 2016: European Radiology
H Bahig, M P Campeau, D Roberge, A Lapointe, S Bedwani, T Vu, L Lambert, J de Guise, C Chartrand-Lefebvre, D Blais, M Lord, P Del Vecchio, E Filion
No abstract text is available yet for this article.
October 1, 2016: International Journal of Radiation Oncology, Biology, Physics
Xingju Zheng, Yuanyuan Liu, Mou Li, Qiyan Wang, Bin Song
OBJECTIVE: A meta-analysis was conducted to determine the accuracy of dual-energy computed tomography (DECT) for differentiating urinary uric acid and calcified calculi. METHODS: The databases PubMed, EMBASE, Web of Science, and the Cochrane Library were searched up to May 2016 for relevant original studies. Data were extracted to calculate the pooled sensitivity, specificity, diagnostic odds ratio (OR), positive and negative likelihood ratios (PLR and NLR), and areas under summary receiver operating characteristic (AUROC) curves for analysis...
October 2016: European Journal of Radiology
Víctor González-Pérez, Estanislao Arana, María Barrios, Albert Bartrés, Julia Cruz, Rafael Montero, Manuel González, Carlos Deltoro, Encarnación Martínez-Pérez, Karol De Aguiar-Quevedo, Miguel Arrarás
PURPOSE: To determine whether parameters generated by Dual-Energy Computed Tomography (DECT) can distinguish malignant from benign lung lesions. METHODS: A prospective review of 125 patients with 126 lung lesions (23 benign and 103 malignant) who underwent lung DECT during arterial phase. All lesions were confirmed by tissue sampling. A radiologist semi-automatically contoured lesions and placed regions of interest (ROIs) in paravertebral muscle (PVM) for normalization...
October 2016: European Journal of Radiology
Kyo Noguchi, Toshihide Itoh, Norihito Naruto, Shutaro Takashima, Kortaro Tanaka, Satoshi Kuroda
BACKGROUND: We evaluated whether X-map, a novel imaging technique, can visualize ischemic lesions within 20 hours after the onset in patients with acute ischemic stroke, using noncontrast dual-energy computed tomography (DECT). MATERIALS AND METHODS: Six patients with acute ischemic stroke were included in this study. Noncontrast head DECT scans were acquired with 2 X-ray tubes operated at 80 kV and Sn150 kV between 32 minutes and 20 hours after the onset. Using these DECT scans, the X-map was reconstructed based on 3-material decomposition and compared with a simulated standard (120 kV) computed tomography (CT) and diffusion-weighted imaging (DWI)...
September 14, 2016: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
Patapong Towiwat, Anthony J Doyle, Gregory D Gamble, Paul Tan, Opetaia Aati, Anne Horne, Lisa K Stamp, Nicola Dalbeth
BACKGROUND: It is currently unknown whether bone erosion in gout occurs through an 'inside-out' mechanism due to direct intra-osseous crystal deposition or through an 'outside-in' mechanism from the surface of bone. The aim of this study was to examine the mechanism ('outside-in' vs. 'inside-out') of monosodium urate (MSU) crystal deposition in bone erosion in gout. Specifically, we used three-dimensional dual-energy computed tomography (DECT) to analyse the positional relationship between bone and MSU crystal deposition in tophaceous gout, and to determine whether intra-osseous crystal deposition occurs in the absence of erosion...
2016: Arthritis Research & Therapy
Jens Altenbernd, Axel Wetter, Michael Forsting, Lale Umutlu
PURPOSE: The aim of this prospective study was to examine the diagnostic value of dual-energy CT (DECT) in the assessment of response of HCC after radioembolisation (RE). MATERIAL AND METHODS: 40 HCC patients with 82 measurable target lesions were included in this study. At baseline and follow-up examination target lesions were evaluated with (IU), AASLD and Choi measurement criteria. Disease control was defined as the sum of complete response (CR), partial response (PR), progression disease (PD) and stable disease (SD)...
2016: European Journal of Radiology Open
Carlos Leiva-Salinas, Lucia Flors, Christopher R Durst, Qinghua Hou, James T Patrie, Max Wintermark, Sugoto Mukherjee
INTRODUCTION: The aims of the study were to compare the diagnostic performance of a combination of virtual non-contrast (VNC) images and arterial images obtained from a single-phase dual-energy CT (DECT) acquisition and standard non-contrast and arterial images from a biphasic protocol and to study the potential radiation dose reduction of the former approach. METHODS: All DECT examinations performed for evaluation of parathyroid adenomas during a 13-month period were retrospectively reviewed...
September 2, 2016: Neuroradiology
E-Ryung Choi, Ho Yun Lee, Ji Yun Jeong, Yoon-La Choi, Jhingook Kim, Jungmin Bae, Kyung Soo Lee, Young Mog Shim
We aimed to compare quantitative radiomic parameters from dual-energy computed tomography (DECT) of lung adenocarcinoma and pathologic complexity. A total 89 tumors with clinical stage I/II lung adenocarcinoma were prospectively included. Fifty one radiomic features were assessed both from iodine images and non-contrast images of DECT datasets. Comprehensive histologic subtyping was evaluated with all surgically resected tumors. The degree of pathologic heterogeneity was assessed using pathologic index and the number of mixture histologic subtypes in a tumor...
August 30, 2016: Oncotarget
Richard J Chaytor, Krishnamoorthy Rajbabu, Paul A Jones, Liam McKnight
OBJECTIVES: This study will evaluate the accuracy of Dual-energy CT (DECT) to characterise urinary tract stone composition on patients presenting to a UK hospital with renal colic. The study will also assess the additional radiation dose burden of DECT over standard protocol. METHODS: Data from 106 DECTs between October 2011 and October 2015 were retrospectively analysed. Patients were imaged using a Toshiba Aquilion ONE™ CT scanner. All patients received a low-dose non-contrast CT of the abdomen and pelvis prior to a stone-targeted DECT at 80 and 135 peak kilovoltages and 40mm field of view...
September 2, 2016: British Journal of Radiology
Suyon Chang, Jin Hur, Dong Jin Im, Young Joo Suh, Yoo Jin Hong, Hye-Jeong Lee, Young Jin Kim, Kyunghwa Han, Dae Joon Kim, Chang Young Lee, Ha Young Shin, Byoung Wook Choi
OBJECTIVES: To investigate the diagnostic value of dual-energy computed tomography (DECT) in differentiating between low- and high-risk thymomas and thymic carcinomas. MATERIALS: Our institutional review board approved this study, and patients provided informed consent. We prospectively enrolled 37 patients (20 males, mean age: 55.6 years) with thymic epithelial tumour. All patients underwent DECT. For quantitative analysis, two reviewers measured the following tumour parameters: CT attenuation value in contrast Hounsfield units (CHU), iodine-related HU and iodine concentration (mg/ml)...
August 23, 2016: European Radiology
Tonghe Wang, Lei Zhu
Conventional dual-energy CT (DECT) reconstruction requires two full-size projection datasets with two different energy spectra. In this study, we propose an iterative algorithm to enable a new data acquisition scheme which requires one full scan and a second sparse-view scan for potential reduction in imaging dose and engineering cost of DECT. A bilateral filter is calculated as a similarity matrix from the first full-scan CT image to quantify the similarity between any two pixels, which is assumed unchanged on a second CT image since DECT scans are performed on the same object...
September 21, 2016: Physics in Medicine and Biology
M Stasinopoulou, A F Fragopoulou, A Stamatakis, G Mantziaras, K Skouroliakou, I S Papassideri, F Stylianopoulou, H Lai, N Kostomitsopoulos, L H Margaritis
In the present study, to evaluate the effects of wireless 1880-1900MHz Digital Enhanced Communication Telephony (DECT) base radiation on fetal and postnatal development, Wistar rats were exposed at an average electric field intensity of 3.7V/m, 12h/day, during pregnancy. After parturition, a group of dams and offspring were similarly exposed for another 22days. Controls were sham-exposed. The data showed that DECT base radiation exposure caused heart rate increase in the embryos on the 17th day of pregnancy...
October 2016: Reproductive Toxicology
M Biondi, E Vanzi, G De Otto, F Banci Buonamici, G M Belmonte, L N Mazzoni, A Guasti, S F Carbone, M A Mazzei, A La Penna, E Foderà, D Guerreri, A Maiolino, L Volterrani
INTRODUCTION: Many studies aimed at validating the application of Dual Energy Computed Tomography (DECT) in clinical practice where conventional CT is not exhaustive. An example is given by bone marrow oedema detection, in which DECT based on water/calcium (W/Ca) decomposition was applied. In this paper a new DECT approach, based on water/cortical bone (W/CB) decomposition, was investigated. MATERIALS AND METHODS: Eight patients suffering from marrow oedema were scanned with MRI and DECT...
August 11, 2016: Physica Medica: PM
Xiaowei Zhu, William P McCullough, Patricia Mecca, Sabah Servaes, Kassa Darge
BACKGROUND: Dual-energy CT technology is available on scanners from several vendors and offers significant advantages over classic single-energy CT technology in multiple clinical applications. Many studies have detailed dual-energy CT applications in adults and several have evaluated the relative radiation dose performance of dual-energy CT in adult imaging. However, little has been published on dual-energy CT imaging in the pediatric population, and the relative dose performance of dual-energy CT imaging in the pediatric population is not well described...
August 12, 2016: Pediatric Radiology
Charlie Chia-Tsong Hsu, Gigi Nga Chi Kwan, Dalveer Singh, Jit Pratap, Trevor William Watkins
Dual-energy computed tomography (DECT) simultaneously acquires images at two X-ray energy levels, at both high- and low-peak voltages (kVp). The material attenuation difference obtained from the two X-ray energies can be processed by software to analyze material decomposition and to create additional image datasets, namely, virtual noncontrast, virtual contrast also known as iodine overlay, and bone/calcium subtraction images. DECT has a vast array of clinical applications in imaging cerebrovascular diseases, which includes: (1) Identification of active extravasation of iodinated contrast in various types of intracranial hemorrhage; (2) differentiation between hemorrhagic transformation and iodine staining in acute ischemic stroke following diagnostic and/or therapeutic catheter angiography; (3) identification of culprit lesions in intra-axial hemorrhage; (4) calcium subtraction from atheromatous plaque for the assessment of plaque morphology and improved quantification of luminal stenosis; (5) bone subtraction to improve the depiction of vascular anatomy with more clarity, especially at the skull base; (6) metal artifact reduction utilizing virtual monoenergetic reconstructions for improved luminal assessment postaneurysm coiling or clipping...
2016: Journal of Clinical Imaging Science
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"