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https://www.readbyqxmd.com/read/28107411/xenon-enhanced-dual-energy-ct-imaging-in-combined-pulmonary-fibrosis-and-emphysema
#1
Keishi Sugino, Masahiro Kobayashi, Yasuhiko Nakamura, Kyoko Gocho, Fumiaki Ishida, Kazutoshi Isobe, Nobuyuki Shiraga, Sakae Homma
BACKGROUND: Little has been reported on the feasibility of xenon-enhanced dual-energy computed tomography (Xe-DECT) in the visual and quantitative analysis of combined pulmonary fibrosis and emphysema (CPFE). OBJECTIVES: We compared CPFE with idiopathic pulmonary fibrosis (IPF) and chronic obstructive pulmonary disease (COPD), as well as correlation with parameters of pulmonary function tests (PFTs). METHODS: Studied in 3 groups were 25 patients with CPFE, 25 with IPF without emphysema (IPF alone), 30 with COPD...
2017: PloS One
https://www.readbyqxmd.com/read/28092407/study-of-potential-health-effects-of-electromagnetic-fields-of-telephony-and-wi-fi-using-chicken-embryo-development-as-animal-model
#2
Henri Woelders, Agnes de Wit, Alexander Lourens, Norbert Stockhofe, Bas Engel, Ina Hulsegge, Dirkjan Schokker, Paula van Heijningen, Stefan Vossen, Dave Bekers, Peter Zwamborn
The objective of this study is to investigate possible biological effects of radiofrequency electromagnetic fields (RF-EMF) as used in modern wireless telecommunication in a well-controlled experimental environment using chicken embryo development as animal model. Chicken eggs were incubated under continuous experimental exposure to GSM (1.8 GHz), DECT (1.88 GHz), UMTS (2.1 GHz), and WLAN (5.6 GHz) radiation, with the appropriate modulation protocol, using a homogeneous field distribution at a field strength of approximately 3 V/m, representing the maximum field level in a normal living environment...
January 16, 2017: Bioelectromagnetics
https://www.readbyqxmd.com/read/28075606/potential-application-of-dual-energy-ct-in-gynecologic-cancer-initial-experience
#3
Ana Paula Benveniste, Silvana de Castro Faria, Gregory Broering, Dhakshina Moorthy Ganeshan, Eric P Tamm, Revathy B Iyer, Priya Bhosale
OBJECTIVE: The purpose of this article is to review the use of dual-energy CT (DECT) in the assessment of gynecologic cancer. CONCLUSION: DECT has the potential to improve diagnostic performance, may improve the ability to differentiate between simple cystic lesions and primary ovarian cancer, and may also improve the detection of musculoskeletal and liver metastases. Additional studies will be needed to determine the direction of future developments and the degree to which DECT will affect the imaging and management of gynecologic cancer...
January 11, 2017: AJR. American Journal of Roentgenology
https://www.readbyqxmd.com/read/28070917/dual-energy-ct-quantitative-imaging-a-comparison-study-between-twin-beam-and-dual-source-ct-scanners
#4
Isabel P Almeida, Lotte E J R Schyns, Michel C Öllers, Wouter van Elmpt, Katia Parodi, Guillaume Landry, Frank Verhaegen
PURPOSE: To assess image quality and to quantify the accuracy of relative electron densities (ρe ) and effective atomic numbers (Zeff ) for three dual-energy computed tomography (DECT) scanners: a novel single-source split-filter (i.e., twin-beam) and two dual-source scanners. METHODS: Measurements were made with a second generation dual-source scanner at 80/140Sn kVp, a third-generation twin-beam single-source scanner at 120 kVp with gold (Au) and tin (Sn) filters, and a third-generation dual-source scanner at 90/150Sn kVp...
January 2017: Medical Physics
https://www.readbyqxmd.com/read/28068248/clinical-implementation-of-dual-energy-ct-for-proton-treatment-planning-on-pseudo-monoenergetic-ct-scans
#5
Patrick Wohlfahrt, Christian Möhler, Volker Hietschold, Stefan Menkel, Steffen Greilich, Mechthild Krause, Michael Baumann, Wolfgang Enghardt, Christian Richter
PURPOSE: To determine whether a standardized clinical application of dual-energy computed tomography (DECT) for proton treatment planning based on pseudomonoenergetic CT scans (MonoCTs) is feasible and increases the precision of proton therapy in comparison with single-energy CT (SECT). METHODS AND MATERIALS: To define an optimized DECT protocol, CT scan settings were analyzed experimentally concerning beam hardening, image quality, and influence on the heuristic conversion of CT numbers into stopping-power ratios (SPRs) and were compared with SECT scans with identical CT dose...
February 1, 2017: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/28065376/dual-energy-ct-virtual-non-calcium-technique-for-detection-of-bone-marrow-edema-in-patients-with-vertebral-fractures-a-prospective-feasibility-study-on-a-single-source-volume-ct-scanner
#6
T Diekhoff, K G Hermann, M Pumberger, B Hamm, M Putzier, M Fuchs
OBJECTIVES: Dual-energy computed tomography (DECT) is a recent development for detecting bone marrow edema (BME) in patients with vertebral compression fractures. The aim of this pilot study was to determine the reliability of single-source DECT in detecting vertebral BME using magnetic resonance imaging (MRI) as standard of reference. MATERIALS AND METHODS: Nine patients with radiographic thoracic or lumbar vertebral compression fractures underwent both, DECT on a 320-row single-source scanner and 1...
February 2017: European Journal of Radiology
https://www.readbyqxmd.com/read/28065375/accessory-spleen-versus-lymph-node-value-of-iodine-quantification-with-dual-energy-computed-tomography
#7
Sebastian Winklhofer, Wei-Ching Lin, Jack W Lambert, Benjamin M Yeh
OBJECTIVES: To evaluate whether iodine quantification with Dual-Energy Computed Tomography (DECT) improves the differentiation of accessory spleens (AS) from lymph nodes (LN) compared to CT number measurements. METHODS: Abdominal DECT images of 75 patients with either AS (n=35) or LN (n=48) (benign entity) were retrospectively evaluated. Hounsfield Units (HU) and iodine concentrations of AS, LN and the main spleen were measured. Receiver operating characteristics (ROC) were performed to calculate an optimal threshold for distinguishing AS from LN...
February 2017: European Journal of Radiology
https://www.readbyqxmd.com/read/28060999/statistical-image-domain-multi-material-decomposition-for-dual-energy-ct
#8
Yi Xue, Ruoshui Ruan, Xiuhua Hu, Yu Kuang, Jing Wang, Yong Long, Tianye Niu
PURPOSE: Dual-energy CT (DECT) enhances tissue characterization because of its basis material decomposition capability. In addition to conventional two-material decomposition from DECT measurements, multi-material decomposition (MMD) is required in many clinical applications. To solve the ill-posed problem of reconstructing multiple-material images from dual-energy measurements, additional constraints are incorporated into the formulation, including volume and mass conservation and the assumptions that at most three materials in each pixel and various material types among pixels...
January 6, 2017: Medical Physics
https://www.readbyqxmd.com/read/28058498/diagnostic-accuracy-of-dual-energy-ct-and-ultrasound-in-gouty-arthritis-a%C3%A2-systematic-review
#9
J Chen, M Liao, H Zhang, D Zhu
OBJECTIVE: The aim of our study was to compare the overall accuracy of ultrasonography (US), with at least one sign positive (double contour, tophus, aggregates), and dual-energy CT in the diagnosis of gouty arthritis. METHODS: PubMed, Web of Science, EI, Elsevier, Wiley Online Library and Cochrane library were systematically searched for studies on the diagnostic performance of dual-energy CT (DECT) and ultrasound (US) from 2005 to February 2016. After study selection, data and quality assessment, the sensitivity (SEN), specificity (SPE), diagnostic odds rate (DOR), positive likelihood ratio (PLR), negative likelihood ratio (NLR) and summary receiver operating contraction racteristic (SROC) curves were calculated...
January 5, 2017: Zeitschrift Für Rheumatologie
https://www.readbyqxmd.com/read/28048802/tu-ab-brc-03-accurate-tissue-characterization-for-monte-carlo-dose-calculation-using-dual-and-multi-energy-ct-data
#10
A Lalonde, H Bouchard
PURPOSE: To develop a general method for human tissue characterization with dual-and multi-energy CT and evaluate its performance in determining elemental compositions and the associated proton stopping power relative to water (SPR) and photon mass absorption coefficients (EAC). METHODS: Principal component analysis is used to extract an optimal basis of virtual materials from a reference dataset of tissues. These principal components (PC) are used to perform two-material decomposition using simulated DECT data...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28048416/su-g-tep2-11-initial-evaluation-of-a-novel-split-filter-dual-energy-ct-for-use-in-radiation-oncology
#11
J Miller, J Huang, T Szczykutowicz, J Bayouth
PURPOSE: To perform an initial evaluation of a novel split-filter dual-energy CT (DECT) system with the goal of understanding the clinical utility and limitations of the system for radiation therapy. METHODS: Several phantoms were imaged using the split-filter DECT technique on the Siemens Edge CT scanner using a range of clinically-relevant doses. The optimum-contrast reconstruction, the mixed reconstruction, and the monoenergetic reconstructions (ranging from 40 keV to 190 keV) were evaluated...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28048043/su-f-j-212-enabling-conventional-cone-beam-ct-with-the-capability-of-dual-energy-imaging-using-a-simple-add-on-beam-modifier
#12
R Vinke, S Takao, K Umegaki, H Shirato, H Peng, L Xing
PURPOSE: In searching for a robust, efficient and cost-effective dual energy cone beam CT (DECBCT) solution for various radiation oncology applications, in particularly for improved proton dose planning/replanning accuracy and DE-CBCT guided radiation therapy, we investigate a novel energy modulation scheme using a beam modifier placed between the source and patient and optimize its geometric configuration for routine clinical use. METHODS: The study was performed using a Hitachi CBCT scanner and the tube voltage was set at 125 kVp...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047924/tu-fg-brb-01-dual-energy-ct-proton-stopping-power-ratio-calibration-and-validation-with-animal-tissues
#13
Y Xie, L Yin, C Ainsley, J McDonough, T Solberg, A Lin, B Teo
PURPOSE: The conversion of Hounsfield Unit (HU) to proton stopping power ratio (SPR) is a main source of uncertainty in proton therapy. In this study, the SPRs of animal tissues were measured and compared with prediction from dual energy CT (DECT) and single energy CT (SECT) calibrations. METHODS: A stoichiometric calibration method for DECT was applied to predict the SPR using CT images acquired at 80 kVp and 140 kVp. The dual energy index was derived based on the HUs of the paired spectral images and used to calculate the SPRs of the materials...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047894/su-f-t-270-a-technique-for-modeling-a-diode-array-into-the-tps-for-lung-sbrt-patient-specific-qa
#14
C Curley, Z Ouhib, T Leventouri
PURPOSE: To accurately match the treatment planning system (TPS) with the measurement environment, where quality assurance (QA) devices are used to collect data, for lung Stereotactic Body Radiation Therapy (SBRT) patient specific QA. Incorporation of heterogeneities is also studied. METHODS: Dual energy computerized tomography (DECT) and single energy computerized tomography (SECT) were used to model phantoms incorporating a 2-D diode array into the TPS. A water-equivalent and a heterogeneous phantom (simulating the thoracic region of a patient) were studied...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047678/su-g-iep3-04-effective-dose-measurements-in-fast-kvp-switch-dual-energy-computed-tomography
#15
J Raudabaugh, G Nguyen, B Moore, C Lowry, R Nelson, T Yoshizumi
PURPOSE: The objective of this study was two-fold: (a) to test a new approach to approximating organ dose by using the effective energy of the combined 80kV/140kV beam in dual-energy (DE) computed tomography (CT), and (b) to derive the effective dose (ED) in the abdomen-pelvis protocol in DECT. METHODS: A commercial dual energy CT scanner was employed using a fast-kV switch abdomen/pelvis protocol alternating between 80 kV and 140 kV. MOSFET detectors were used for organ dose measurements...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047418/su-f-j-195-on-the-performance-of-four-dual-energy-ct-formalisms-for-extracting-proton-stopping-powers
#16
E Baer, A Lalonde, G Royle, H Bouchard
PURPOSE: Dual energy CT can predict stopping power ratios (SPR) for ion therapy treatment planning. Several approaches have been proposed recently, however accuracy and practicability in a clinical workflow are unaddressed. The aim of this work is to provide a fair comparison of available approaches in a human-like phantom to find the optimal method for tissue characterization in a clinical situation. METHODS: The SPR determination accuracy is investigated using simulated DECT images...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047256/tu-fg-brb-02-the-impact-of-using-dual-energy-ct-for-determining-proton-stopping-powers-comparison-between-theory-and-experiments
#17
E Baer, K Jee, R Zhang, A Lalonde, K Yang, G Sharp, G Royle, B Liu, H Bouchard, H Lu
PURPOSE: To evaluate the clinical performance of dual-energy CT (DECT) in determining proton stopping power ratios (SPR) and demonstrate advantages over conventional single-energy CT (SECT). METHODS: SECT and DECT scans of tissue-equivalent plastics as well as animal meat samples are performed with a Siemens SOMATOM Definition Flash. The methods of Schneider et al. (1996) and Bourque et al. (2014) are used to determine proton SPR on SECT and DECT images, respectively...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047208/su-f-t-398-improving-radiotherapy-treatment-planning-using-dual-energy-computed-tomography-based-tissue-characterization
#18
N Tomic, H Bekerat, J Seuntjens, R Forghani, F DeBlois, S Devic
PURPOSE: Both kVp settings and geometric distribution of various materials lead to significant change of the HU values, showing the largest discrepancy for high-Z materials and for the lowest CT scanning kVp setting. On the other hand, the dose distributions around low-energy brachytherapy sources are highly dependent on the architecture and composition of tissue heterogeneities in and around the implant. Both measurements and Monte Carlo calculations show that improper tissue characterization may lead to calculated dose errors of 90% for low energy and around 10% for higher energy photons...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28046904/th-cd-202-05-dect-based-tissue-segmentation-as-input-to-monte-carlo-simulations-for-proton-treatment-verification-using-pet-imaging
#19
B Berndt, T Tessonnier, F Schwarz, J Bauer, M Wuerl, F Kamp, C Thieke, C Belka, F Verhaegen, M Reiser, W Sommer, G Dedes, G Landry, K Parodi
PURPOSE: To improve agreement of predicted and measured positron emitter yields in patients, after proton irradiation for PET-based treatment verification, using a novel dual energy CT (DECT) tissue segmentation approach, overcoming known deficiencies from single energy CT (SECT). METHODS: DECT head scans of 5 trauma patients were segmented and compared to existing decomposition methods with a first focus on the brain. For validation purposes, three brain equivalent solutions [water, white matter (WM) and grey matter (GM) - equivalent with respect to their reference carbon and oxygen contents and CT numbers at 90kVp and 150kVp] were prepared from water, ethanol, sucrose and salt...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28046834/su-f-j-91-sparing-lung-function-in-treatment-planning-using-dual-energy-tomography
#20
A Lapointe, H Bahig, K Zerouali, D Blais, J De Guise, J Carrier, E Filion, D Roberge, S Bedwani
PURPOSE: To propose an alternate treatment plan that minimizes the dose to the functional lung tissues. In clinical situation, the evaluation of the lung functionality is typically derived from perfusion scintigraphy. However, such technique has spatial and temporal resolutions generally inferior to those of a CT scan. Alternatively, it is possible to evaluate pulmonary function by analysing the iodine concentration determined via contrast-enhanced dual energy CT (DECT) scan. METHODS: Five lung cancer patients underwent a scintigraphy and a contrast-enhanced DECT scan (SOMATOM Definition Flash, Siemens)...
June 2016: Medical Physics
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