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Xiaolei Shi, Yonghan Peng, Xiao Li, Qi Wang, Ling Li, Min Liu, Xiaofeng Gao, Yinghao Sun
PURPOSES: To evaluate the clinical efficacy, safety, and cost of retrograde intrarenal surgery (RIRS) and percutaneous nephrolithotomy (PCNL) in the treatment for large renal stones in patients with a solitary kidney. PATIENTS AND METHODS: In this study, 117 patients with a solitary kidney who had undergone PCNL or RIRS for renal stones larger than 2 cm between January 2010 and December 2016 were retrospectively evaluated. The patients' demographic data, clinical characteristics, and perioperative outcomes were collected through a review of their medical records...
December 6, 2017: Journal of Endourology
James Steele, Andreas Endres, James Fisher, Paulo Gentil, Jürgen Giessing
'Repetitions in Reserve' (RIR) scales in resistance training (RT) are used to control effort but assume people accurately predict performance a priori (i.e. the number of possible repetitions to momentary failure (MF)). This study examined the ability of trainees with different experience levels to predict number of repetitions to MF. One hundred and forty-one participants underwent a full body RT session involving single sets to MF and were asked to predict the number of repetitions they could complete before reaching MF on each exercise...
2017: PeerJ
Dirk R Rutgers, Fleur van Raamt, Anouk van der Gijp, Christian Mol, Olle Ten Cate
RATIONALE AND OBJECTIVES: The psychometric characteristics of image-based test items in radiological written examinations are not well known. In this study, we explored difficulty and discriminating power of these test items in postgraduate radiological digital examinations. MATERIALS AND METHODS: We reviewed test items of seven Dutch Radiology Progress Tests (DRPTs) that were taken from October 2013 to April 2017. The DRPT is a semiannual formative examination, required for all Dutch radiology residents...
November 29, 2017: Academic Radiology
Alfredo Berrettini, Luca Boeri, Emanuele Montanari, Mirella Mogiatti, Pietro Acquati, Elisa De Lorenzis, Andrea Gallioli, Erika Adalgisa De Marco, Dario Guido Minoli, Gianantonio Manzoni
INTRODUCTION: Surgical treatment of pediatric kidney stones has changed dramatically in recent years because of the miniaturization of surgical instruments and the availability of intracorporeal lithotripters. The retrograde intrarenal surgery (RIRS) technique is nowadays considered an effective and safe procedure but studies in very young children are lacking and use of a ureteral access sheath (UAS) has also been debated. OBJECTIVE: To assess safety and efficacy of RIRS using UAS in children weighing < 20 kg...
November 11, 2017: Journal of Pediatric Urology
Spencer C Behr, Brett J Mollard, Jaewon Yang, Robert R Flavell, Randall A Hawkins, Youngho Seo
Recent technical advances in positron emission tomography/magnetic resonance imaging (PET/MRI) technology allow much improved time-of-flight (TOF) and regularized iterative PET reconstruction regularized iterative reconstruction (RIR) algorithms. We evaluated the effect of TOF and RIR on standardized uptake values (maximum and peak SUV [SUVmax and SUVpeak]) and their metabolic tumor volume dependencies and visual image quality for (18)F-fluorocholine PET/MRI in patients with newly diagnosed prostate cancer...
January 2017: Molecular Imaging
Yinglong Xiao, Deng Li, Lei Chen, Yaoting Xu, Dingguo Zhang, Yi Shao, Jun Lu
BACKGROUND: To establish and internally validate an innovative R.I.R.S. scoring system that allows urologists to preoperatively estimate the stone-free rate (SFR) after retrograde intrarenal surgery (RIRS). METHODS: This study included 382 eligible samples from a total 573 patients who underwent RIRS from January 2014 to December 2016. Four reproducible factors in the R.I.R.S. scoring system, including renal stone density, inferior pole stone, renal infundibular length and stone burden, were measured based on preoperative computed tomography of urography to evaluate the possibility of stone clearance after RIRS...
November 21, 2017: BMC Urology
Juan Téllez, Albert Gallen, Joaquina Ferrer, Fernando J Lahoz, Pilar García-Orduña, Antoni Riera, Xavier Verdaguer, Daniel Carmona, Arnald Grabulosa
The reaction of the acetylacetonates [(η(5)-C5Me5)M(acac)Cl] with (SP)-[HMaxPhos][BF4] afforded cationic complexes with the formula (SM,RP)-[(η(5)-C5Me5)MCl(MaxPhos)][BF4] (M = Rh (1), Ir (2)). The reaction of (SP)-MaxPhos with [RuCl(μ-Cl)(η(6)-p-MeC6H4(i)Pr)]2 and NH4X afforded (SRu,RP)-[(η(6)-p-MeC6H4(i)Pr)RuCl(MaxPhos)][X] (X = BF4 (3), PF6 (3')). The complexes have been completely characterized by analytical and spectroscopic means, including the determination of the crystal structures of 1, 2 and 3'...
November 21, 2017: Dalton Transactions: An International Journal of Inorganic Chemistry
Jianzhong Fan, Lei Cai, Lili Lin, Chuan-Kui Wang
Highly efficient organic light-emitting diodes (OLEDs) based on fluorescent emitters with a hybridized local and charge transfer (HLCT) state have attracted significant attention. Recently, a near-infrared fluorescent compound, 2,3-bis(4'-(diphenylamino)-[1,1'-biphenyl]-4-yl)fumaronitrile (TPATCN), with an HLCT state has been synthetized, and the features of OLEDs based on this compound have been explored. In this study, excited state dynamics of TPATCN in the solid phase has been theoretically studied through a combined quantum mechanics and molecular mechanics (QM/MM) method...
November 7, 2017: Physical Chemistry Chemical Physics: PCCP
Jianzhong Fan, Lili Lin, Chuan-Kui Wang
The photoluminescence quantum yield (PLQY) and charge transfer property of the high mobility emissive organic semiconductors, 2,6-diphenylanthracene (DPA) and 2,6-diphenyl-9,10-bis(phenylethynyl)anthracene (DP-BPEA), are theoretically investigated. A quantum mechanics/molecular mechanics (QM/MM) method is adopted to investigate the photophysical properties, the Marcus equation is used to describe hole and electron transfer rates, and kinetic Monte Carlo simulation is performed to obtain charge mobility. In both solution and solid phase, the PLQY and the charge mobility of DPA and DP-BPEA are calculated, and the molecular stacking effect is analyzed...
November 6, 2017: Physical Chemistry Chemical Physics: PCCP
Kai Li, Yuanyuan Liu, Yuanyuan Li, Qi Feng, Hongwei Hou, Ben Zhong Tang
Aggregation-induced emission luminogens (AIEgens) have attracted extensive interest for their outstanding luminescence properties in the aggregated state and even in the solid state. In this work, we developed a series of novel AIEgens based on 2,5-bis(4-alkoxycarbonylphenyl)-1,4-diaryl-1,4-dihydropyrrolo[3,2-b]pyrrole (AAPP). The AIEgens can be facilely synthesized through a single-step reaction under mild conditions with satisfactory yields. Interestingly, AAPP was found to have multiple luminous mechanisms that result in variable fluorescence properties...
October 1, 2017: Chemical Science
Pei Lu, Rijin Song, Yuzhou Yu, Jie Yang, Kai Qi, Rongzhen Tao, Keliang Chen, Wei Zhang, Min Gu
BACKGROUND: Percutaneous nephrolithotomy (PCNL) and retrograde intrarenal surgery (RIRS) are widely used for pediatric upper tract stones; however, comparisons of their clinical efficacies are needed. METHODS: Literature searches for relevant articles were performed using PubMed, the Cochrane Central Register of Controlled Trials, Embase and the China CNKI database. Study quality was assessed by Jadad and Newcastle-Ottawa Scales. Standard mean differences (SMDs) or odds ratios (OR), and 95% confidential intervals (95% CIs) were pooled for meta-analysis...
October 2017: Medicine (Baltimore)
Massimo Fabiani, Gianluigi Ferrante, Valentina Minardi, Cristina Giambi, Flavia Riccardo, Silvia Declich, Maria Masocco
BACKGROUND: International migration rapidly increased in the last decade, raising a renewed attention to its impact on public health. We evaluated differences in rubella immunization rate (RIR) between immigrant and Italian women of childbearing age and tried to identify the driving factors causing them. METHODS: We analyzed data from the Italian behavioral surveillance system PASSI collected in 2011-2015 in a nationally representative sample of residents in Italy...
2017: PloS One
Xiao-Shuai Gao, Bang-Hua Liao, Yun-Tian Chen, Shi-Jian Feng, Rang Gao, De-Yi Luo, Jia-Ming Liu, Kun-Jie Wang
PURPOSE: Miniaturized percutaneous nephrolithotomy (MPCNL), including minipercutaneous nephrolithotomy (PCNL), ultramini-PCNL, and micro-PCNL, have been developed recently. The aim of this meta-analysis was to compare the safety and efficacy of different tract sizes of MPCNL with retrograde intrarenal surgery (RIRS) in the management of kidney stones. MATERIALS AND METHODS: We searched PubMed, Embase, and Web of Science to identify case-control trials and randomized controlled trials, which evaluated MPCNL vs RIRS before February 2017...
November 2017: Journal of Endourology
Jingqi Han, Xin Zhang, Hao Li, Yue Hou, Jingdan Hou, Zhongfeng Li, Feng Yang, Yang Liu, Tianyu Han
In this work, we synthesize a series of compounds with electron donor (D) and acceptor (A) units. They show general solvent effect in aprotic solvents, suggesting a charge transfer (CT) process. While in protic solvents including water, ethanol and methanol, the spectra exert no polarity-dependence but a remarkable hypochromatic shift together with the fading of CT band. Dynamic analysis implies that intermolecular hydrogen bond will be formed between carboxylic acid and protic solvent, boosting another deactivation pathway that jumps off a bigger energy gap, in other words, favoring the locally excited (LE) state emission...
September 20, 2017: Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy
Joseph McGinn, Fangming Zhang, Monowar Aziz, Weng-Lang Yang, Jeffrey Nicastro, Gene F Coppa, Ping Wang
Extracellular cold-inducible RNA-binding protein (CIRP) functions as damage-associated molecular pattern (DAMP) and has been demonstrated to be responsible in part for the damage occurring after renal ischemia-reperfusion (I/R). A short peptide derived from CIRP, named C23, binds to myeloid differentiation factor 2 (MD2), a Toll-like receptor 4 (TLR4) co-receptor. We hypothesize that C23 reduces renal ischemia-reperfusion (RIR) injury by blocking CIRP. We observed that pre-treatment with C23 significantly decreased the levels of recombinant mouse CIRP-induced TNF-α in a dose-dependent fashion in cultured macrophages...
September 19, 2017: Shock
Zhaohui Liu, Junjie Zhang, Shitong Li, Jihong Jiang
Artesunate (AS), a semi-synthetic derivative of Artemisia, has been shown to exert a wide range of pharmacological effects, such as anti-inflammatory and antioxidant functions. However, the protective functions of AS on renal ischemia reperfusion injury (RIR)-stimulated lung inflammation remain unclear. In this research, acute lung injury (ALI) was stimulated by renal ischemia reperfusion injury (RIR). AS (15 mg/kg) was intraperitoneal administrated to rat 1 h before RIR stimulation. Serum and pulmonary NO, MDA, IL-6, MIP-2, and PGE2 levels, arterial blood gas and biochemistry, lung wet/dry weight ratio and MPO activity, total cell number and protein concentration in BALF, tissue histology, and NF-κB expression were determined...
September 18, 2017: Inflammation
Mehmet Hamza Gültekin, Fethi Ahmet Türegün, Burak Ozkan, Beril Tülü, Gamze Gül Güleç, Nejat Tansu, Çetin Demirdağ, Pınar Kendigelen, Ahmet Erözenci, Bülent Önal
PURPOSE: To evaluate the effects of previous ipsilateral open renal stone surgery (ORSS) on outcomes of extracorporeal shockwave lithotripsy (SWL) in adults with renal stones. MATERIALS AND METHODS: A total of 2097 renal units with renal stones underwent SWL treatment at our institution between March 1997 and February 2013. One thousand eight hundred thirty-nine (87.7%) of these had no history of ORSS and were categorized as group 1, and 258 (12.3%) patients having history of ipsilateral ORSS were categorized as group 2...
October 10, 2017: Journal of Endourology
G Bozzini, P Verze, D Arcaniolo, O Dal Piaz, N M Buffi, G Guazzoni, M Provenzano, B Osmolorskij, F Sanguedolce, E Montanari, N Macchione, K Pummer, V Mirone, M De Sio, G Taverna
PURPOSE: To prospectively evaluate the efficacy and safety of RIRS, SWL and PCNL for lower calyceal stones sized 1-2 cm. MATERIALS AND METHODS: Patients with a single lower calyceal stone with an evidence of a CT diameter between 1 and 2 cm were enrolled in this multicenter, randomized, unblinded, clinical trial study. Patients were randomized into three groups: group A: SWL (194 pts); group B: RIRS (207 pts); group C: PCNL (181 pts). Patients were evaluated with KUB radiography (US for uric acid stones) at day 10 and a CT scan after 3 months...
December 2017: World Journal of Urology
Hacı İbrahim Çimen, Fikret Halis, Hasan Salih Sağlam, Ahmet Gökçe
OBJECTIVE: The aim of this study was to present outcomes of our patients who had undergone retrograde intrarenal surgery (RIRS) with fluoroscopy-free technique and evaluate the efficacy and safety of the technique. MATERIAL AND METHODS: Between January 2013 and June 2015 the outcomes of 93 patients who had undergone RIRS with fluoroscopy-free technique were retrospectively evaluated. Our RIRS technique involved preoperative assessment of ureter by semi-rigid ureteroscope, inserting guidewire through semi-rigid ureteroscope, inserting ureteral access sheath over the guidewire with the visiual guidance of semi-rigid ureteroscope, passing flexible ureteroscope through the sheath, dusting the stone with holmium laser, rechecking the ureter with semi-rigid ureteroscope and inserting double J stent through semi-rigid ureteroscope...
September 2017: Turkish Journal of Urology
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