keyword
MENU ▼
Read by QxMD icon Read
search

Artificial

keyword
https://www.readbyqxmd.com/read/27933367/antipsychotic-inductors-of-brain-hypothermia-and-torpor-like-states-perspectives-of-application
#1
REVIEW
Yury S Tarahovsky, Irina S Fadeeva, Natalia P Komelina, Maxim O Khrenov, Nadezhda M Zakharova
Hypothermia and hypometabolism (hypometabothermia) normally observed during natural hibernation and torpor, allow animals to protect their body and brain against the damaging effects of adverse environment. A similar state of hypothermia can be achieved under artificial conditions through physical cooling or pharmacological effects directed at suppression of metabolism and the processes of thermoregulation. In these conditions called torpor-like states, the mammalian ability to recover from stroke, heart attack, and traumatic injuries greatly increases...
December 8, 2016: Psychopharmacology
https://www.readbyqxmd.com/read/27933324/effect-of-aqueous-storage-on-original-and-repair-bond-strength-and-residual-monomer-release-of-fiberreinforced-composites
#2
Diana Wolff, Michael Coupek, Ralf Erber, Tanja Krueger, Johannes Krisam, Hans Joerg Staehle, Cornelia Frese
PURPOSE: To evaluate the effects of aqueous storage on shear bond strength (SBS) and monomer release of fiberreinforced composites (FRCs). MATERIALS AND METHODS: Four unidirectional FRCs were tested, including one semi-interpenetrating polymer network (IPN) (ES, everStick) and three cross-linked polymer (CLP) FRCs (GT, GrandTec; TF, TenderFiber; DP, Dentapreg). The SBS of samples of original resin to fresh FRC with an intact oxygen inhibition layer (n = 30/group) and repair resin to FRC after surface treatment (n = 30/group) was evaluated after 6 and 12 months of storage in artificial saliva...
December 8, 2016: Journal of Adhesive Dentistry
https://www.readbyqxmd.com/read/27933225/rational-design-of-dual-active-sites-in-a-single-protein-scaffold-a-case-study-of-heme-protein-in-myoglobin
#3
Xiao-Gang Shu, Ji-Hu Su, Ke-Jie Du, Yong You, Shu-Qin Gao, Ge-Bo Wen, Xiangshi Tan, Ying-Wu Lin
Rational protein design has been proven to be a powerful tool for creating functional artificial proteins. Although many artificial metalloproteins with a single active site have been successfully created, those with dual active sites in a single protein scaffold are still relatively rare. In this study, we rationally designed dual active sites in a single heme protein scaffold, myoglobin (Mb), by retaining the native heme site and creating a copper-binding site remotely through a single mutation of Arg118 to His or Met...
June 2016: ChemistryOpen
https://www.readbyqxmd.com/read/27932722/the-use-of-prid-delta-versus-cidr-in-dairy-cattle-and-subsequent-pregnancy-rate-with-artificial-insemination
#4
Hannah Doit, Natalie Robinson
No abstract text is available yet for this article.
December 10, 2016: Veterinary Record
https://www.readbyqxmd.com/read/27931100/photocaged-g-quadruplex-dnazyme-and-aptamer-by-postsynthetic-modification-on-phosphodiester-backbone
#5
Mengli Feng, Zhiyuan Ruan, Jiachen Shang, Lu Xiao, Aijun Tong, Yu Xiang
G-quadruplex-containing DNAzymes and aptamers are widely applied in many research fields because of their high stability and prominent activities versus the protein counterparts. In this work, G-quadruplex DNAs were equipped with photolabile groups to construct photocaged DNAzymes and aptamers. We incorporated TEEP-OH (thioether-enol phosphate, phenol substituted) into phosphodiester backbone of G-quadruplex DNA by a facile postsynthetic method to achieve efficient photocaging of their activities. Upon light irradiation, the peroxidase-mimicking activity of the caged G-quadruplex DNAzyme was activated, through the transformation of TEEP-OH into a native DNA phos-phodiester without any artificial scar...
December 9, 2016: Bioconjugate Chemistry
https://www.readbyqxmd.com/read/27930956/removal-of-boron-and-fluoride-in-wastewater-using-mg-al-layered-double-hydroxide-and-mg-al-oxide
#6
Tomohito Kameda, Jumpei Oba, Toshiaki Yoshioka
Mg-Al layered double hydroxide intercalated with NO3(-) and Mg-Al oxide were found to remove hazardous materials such as B and As, as well as Cl(-) and SO4(2-), from artificial and real hot spring wastewater. However, compared with the mixture of Al2(SO4)3 and Ca(OH)2, both adsorbents were inferior for the removal of B from real hot spring wastewater. Both adsorbents were also found to remove F(-) and PO4(3-) from artificial semiconductor plant wastewater. Both adsorbents have the same ability to remove B from landfill wastewater as the mixture of Al2(SO4)3 and Ca(OH)2; furthermore, both remove Cl(-), Br(-), and SO4(2-)...
December 5, 2016: Journal of Environmental Management
https://www.readbyqxmd.com/read/27930846/dark-photocatalysis-storage-of-solar-energy-in-carbon-nitride-for-time-delayed-hydrogen-generation
#7
Vincent Wing-Hei Lau, Daniel Klose, Hatice Kasap, Filip Podjaski, Marie-Claire Pignié, Erwin Reisner, Gunnar Jeschke, Bettina V Lotsch
While natural photosynthesis serves as the model system for efficient charge separation and decoupling of redox reactions, bio-inspired artificial systems typically lack applicability owing to synthetic challenges and structural complexity. We present herein a simple and inexpensive system that, under solar irradiation, forms highly reductive radicals in the presence of an electron donor, with lifetimes exceeding the diurnal cycle. This radical species is formed within a cyanamide-functionalized polymeric network of heptazine units and can give off its trapped electrons in the dark to yield H2 , triggered by a co-catalyst, thus enabling the temporal decoupling of the light and dark reactions of photocatalytic hydrogen production through the radical's longevity...
December 8, 2016: Angewandte Chemie
https://www.readbyqxmd.com/read/27930604/an-automated-expanded-polytetrafluoroethylene-suturing-and-coaxial-fastener-system-for-mitral-chordae-replacement-strength-feasibility-and-healing
#8
Candice Y Lee, Joshua K Wong, Jude S Sauer, Heather R Gorea, Angelo J Martellaro, Andrew R Sifain, Peter A Knight
OBJECTIVE: Mitral valve (MV) chordae replacements can be technically challenging. Technology that remotely delivers and accurately secures artificial chordae may reduce the learning curve and improve the reliability of MV repairs. METHODS: The technology involved two devices: a remote suturing device for delivery of expanded polytetrafluoroethylene (ePTFE) suture to the papillary muscle and a Coaxial titanium suture fastener (TF) device with integrated saline infusion for real-time determination of chordae length during fixation...
December 7, 2016: Innovations: Technology and Techniques in Cardiothoracic and Vascular Surgery
https://www.readbyqxmd.com/read/27930301/reprogramming-cell-fate-with-a-genome-scale-library-of-artificial-transcription-factors
#9
Asuka Eguchi, Matthew J Wleklinski, Mackenzie C Spurgat, Evan A Heiderscheit, Anna S Kropornicka, Catherine K Vu, Devesh Bhimsaria, Scott A Swanson, Ron Stewart, Parameswaran Ramanathan, Timothy J Kamp, Igor Slukvin, James A Thomson, James R Dutton, Aseem Z Ansari
Artificial transcription factors (ATFs) are precision-tailored molecules designed to bind DNA and regulate transcription in a preprogrammed manner. Libraries of ATFs enable the high-throughput screening of gene networks that trigger cell fate decisions or phenotypic changes. We developed a genome-scale library of ATFs that display an engineered interaction domain (ID) to enable cooperative assembly and synergistic gene expression at targeted sites. We used this ATF library to screen for key regulators of the pluripotency network and discovered three combinations of ATFs capable of inducing pluripotency without exogenous expression of Oct4 (POU domain, class 5, TF 1)...
December 5, 2016: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/27929721/a-randomized-multicenter-study-comparing-0-1-0-15-and-0-3-sodium-hyaluronate-with-0-05-cyclosporine-in-the-treatment-of-dry-eye
#10
Yuli Park, Jong Suk Song, Chul Young Choi, Kyung Chul Yoon, Hyung Keun Lee, Hyun Seung Kim
PURPOSE: To investigate the efficacy of 0.1%, 0.15%, and 0.3% sodium hyaluronate (SH) artificial tears compared with 0.05% cyclosporine (CS) ophthalmic solution for the treatment of dry eye. METHODS: One hundred seventy-six patients were recruited and randomized to receive of 0.1%, 0.15%, and 0.3% SH and 0.05% CS. There was a primary end point which is the changes in the fluorescein corneal staining (FCS) score to determine noninferiority of 0.1%, 0.15%, and 0.3% SH...
December 8, 2016: Journal of Ocular Pharmacology and Therapeutics
https://www.readbyqxmd.com/read/27928658/analog-computer-aided-detection-cad-information-can-be-more-effective-than-binary-marks
#11
Corbin A Cunningham, Trafton Drew, Jeremy M Wolfe
In socially important visual search tasks, such as baggage screening and diagnostic radiology, experts miss more targets than is desirable. Computer-aided detection (CAD) programs have been developed specifically to improve performance in these professional search tasks. For example, in breast cancer screening, many CAD systems are capable of detecting approximately 90% of breast cancer, with approximately 0.5 false-positive detections per image. Nevertheless, benefits of CAD in clinical settings tend to be small (Birdwell, 2009) or even absent (Meziane et al...
December 7, 2016: Attention, Perception & Psychophysics
https://www.readbyqxmd.com/read/27928553/proliferation-of-the-biocontrol-agent-fusarium-oxysporum-f-sp-strigae-and-its-impact-on-indigenous-rhizosphere-fungal-communities-in-maize-under-different-agro-ecologies
#12
Judith Zimmermann, Mary K Musyoki, Georg Cadisch, Frank Rasche
Our objectives were to (1) monitor the proliferation of the biocontrol agent (BCA) Fusarium oxysporum f. sp. strigae strain "Foxy-2", an effective soil-borne BCA against the parasitic weed Striga hermonthica, in the rhizosphere of maize under different agro-ecologies, and (2) investigate its impact on indigenous rhizosphere fungal community abundance and composition. Field experiments were conducted in Busia and Homa Bay districts in western Kenya during two cropping seasons to account for effects of soil type, climate, growth stage and seasonality...
June 2016: Rhizosphere
https://www.readbyqxmd.com/read/27928518/prenatal-transmission-of-scrapie-in-sheep-and-goats-a-case-study-for-veterinary-public-health
#13
REVIEW
D B Adams
Unsettled knowledge as to whether scrapie transmits prenatally in sheep and goats and transmits by semen and preimplantation embryos has a potential to compromise measures for controlling, preventing and eliminating the disease. The remedy may be analysis according to a systematic review, allowing comprehensive and accessible treatment of evidence and reasoning, clarifying the issue and specifying the uncertainties. Systematic reviews have clearly formulated questions, can identify relevant studies and appraise their quality and can summarise evidence and reasoning with an explicit methodology...
2016: Open veterinary journal
https://www.readbyqxmd.com/read/27928494/synthetically-tuneable-biomimetic-artificial-photosynthetic-reaction-centres-that-closely-resemble-the-natural-system-in-purple-bacteria
#14
Sai-Ho Lee, Iain M Blake, Allan G Larsen, James A McDonald, Kei Ohkubo, Shunichi Fukuzumi, Jeffrey R Reimers, Maxwell J Crossley
Porphyrin-based photosynthetic reaction centre (PRC) mimics, ZnPQ-Q2HP-C60 and MP2Q-Q2HP-C60 (M = Zn or 2H), designed to have a similar special-pair electron donor and similar charge-separation distances, redox processes and photochemical reaction rates to those in the natural PRC from purple bacteria, have been synthesised and extensive photochemical studies performed. Mechanisms of electron-transfer reactions are fully investigated using femtosecond and nanosecond transient absorption spectroscopy. In benzonitrile, all models show picosecond-timescale charge-separations and the final singlet charge-separations with the microsecond-timescale...
October 19, 2016: Chemical Science
https://www.readbyqxmd.com/read/27928455/effects-of-esomeprazole-on-the-healing-process-of-post-endoscopic-submucosal-dissection-gastric-ulcers-a-single-arm-prospective-trial
#15
Takashi Ichida, Fumihiko Kusano, Yoshinori Sakai
Objectives: Gastric endoscopic submucosal dissection (ESD) is currently a standard procedure. ESD enables en-bloc resection of large lesions, while inducing larger artificial ulcers to a greater extent than conventional procedures. Several studies have reported that proton pump inhibitors (PPIs) prevent delayed bleeding and expedite the artificial ulcer healing process. Esomeprazole, an S-isomer of omeprazole, is reportedly one of strongest inhibitors of gastric acid secretion. Previous studies have examined the effectiveness of esomeprazole...
2016: Journal of Rural Medicine: JRM
https://www.readbyqxmd.com/read/27928240/color-stability-of-nanofilled-and-microhybrid-resin-based-composites-following-exposure-to-chlorhexidine-mouthrinses-an-in-vitro-study
#16
Mahmood Khosravi, Behnaz Esmaeili, Forough Nikzad, Soraya Khafri
OBJECTIVES: This study aimed to evaluate the effects of chlorhexidine mouthrinses on color stability of nanofilled and micro-hybrid resin-based composites. MATERIALS AND METHODS: In this in-vitro study, 160 disc-shaped specimens (7x2mm) were fabricated of Filtek Z250 and Filtek Z350XT Enamel (A2 shade). The samples of each group were randomly divided into eight subgroups (n=10). The specimens were incubated in artificial saliva at 37°C for 24 hours. The baseline color values (L*, a*, b*) of each specimen were measured according to CIE LAB system using a reflection spectrophotometer...
March 2016: Journal of Dentistry of Tehran University of Medical Sciences
https://www.readbyqxmd.com/read/27928237/effect-of-accelerated-artificial-aging-on-translucency-of-methacrylate-and-silorane-based-composite-resins
#17
Mehdi Shirinzad, Loghman Rezaei-Soufi, Maryam Sadat Mirtorabi, Farshid Vahdatinia
OBJECTIVES: Composite restorations must have tooth-like optical properties namely color and translucency and maintain them for a long time. This study aimed to compare the effect of accelerated artificial aging (AAA) on the translucency of three methacrylate-based composites (Filtek Z250, Filtek Z250XT and Filtek Z350XT) and one silorane-based composite resin (Filtek P90). MATERIALS AND METHODS: For this in vitro study, 56 composite discs were fabricated (n=14 for each group)...
March 2016: Journal of Dentistry of Tehran University of Medical Sciences
https://www.readbyqxmd.com/read/27928235/diagnostic-accuracy-of-cbct-with-different-voxel-sizes-and-intraoral-digital-radiography-for-detection-of-periapical-bone-lesions-an-ex-vivo-study
#18
Shirin Sakhdari, Ahmad Reza Talaeipour, Maziar Talaeipour, Maryam Pazhutan, Sanaz Heidarkhan Tehrani, Mohammad Javad Kharazifard
OBJECTIVES: This study sought to assess the diagnostic accuracy of cone beam computed tomography (CBCT) with different voxel sizes and intraoral digital radiography with photostimulable phosphor (PSP) plate for detection of periapical (PA) bone lesions. MATERIALS AND METHODS: In this ex vivo diagnostic study, one-millimeter defects were created in the alveolar sockets of 15 bone blocks, each with two posterior teeth. A no-defect control group was also included. Digital PA radiographs with PSP plates and CBCT scans with 200, 250 and 300μ voxel sizes were obtained...
March 2016: Journal of Dentistry of Tehran University of Medical Sciences
https://www.readbyqxmd.com/read/27928143/degradation-of-distillery-lees-shochu-kasu-by-cellulase-producing-thraustochytrids
#19
Yousuke Taoka, Naoki Nagano, Hiroyuki Kai, Masahiro Hayashi
Single cell oils produced by oleaginous microorganisms have attracted increasing interests as a petroleum alternative energy. Marine eukaryotes, thraustochytrids were heterotrophic, and can grow rapidly and accumulate large amount of lipids containing functional fatty acids, such as docosahexaenoic acid (DHA) in their cells body. In this investigation, thraustochytrids isolated from marine environment were cultured in the medium containing an industrial waste and an unused resource, distillery lees (Shochu kasu) to produce biofuel or functional fatty acids by microorganisms...
December 8, 2016: Journal of Oleo Science
https://www.readbyqxmd.com/read/27928030/emerging-therapies-for-inherited-retinal-degeneration
#20
REVIEW
Hendrik P N Scholl, Rupert W Strauss, Mandeep S Singh, Deniz Dalkara, Botond Roska, Serge Picaud, José-Alain Sahel
Inherited retinal degenerative diseases, a genetically and phenotypically heterogeneous group of disorders, affect the function of photoreceptor cells and are among the leading causes of blindness. Recent advances in molecular genetics and cell biology are elucidating the pathophysiological mechanisms underlying these disorders and are helping to identify new therapeutic approaches, such as gene therapy, stem cell therapy, and optogenetics. Several of these approaches have entered the clinical phase of development...
December 7, 2016: Science Translational Medicine
keyword
keyword
53482
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"