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Atherosclerotic stenosis

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https://www.readbyqxmd.com/read/28318958/the-association-between-carotid-artery-atherosclerosis-and-silent-brain-infarction-a-systematic-review-and-meta-analysis
#1
Caitlin Finn, Ashley E Giambrone, Gino Gialdini, Diana Delgado, Hediyeh Baradaran, Hooman Kamel, Ajay Gupta
BACKGROUND: Carotid atherosclerosis is responsible for ~20% of ischemic strokes, but it is unclear whether carotid disease is associated with the presence of downstream silent brain infarction (SBI). We performed a systematic review and meta-analysis to study the relationship between SBI and 2 separate manifestations of carotid atherosclerosis, carotid intima-media thickening (IMT) and luminal stenosis. METHODS: Ovid MEDLINE, Ovid Embase, and the Cochrane Library Database were searched with an additional search of references and citing articles of target studies...
March 15, 2017: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/28317478/homocysteine-and-non-cardiac-vascular-disease
#2
Niki Katsiki, Pablo Perez-Martinez, Dimitri P Mikhailidis
Elevated homocysteine (Hcy) levels are predictors of cardiovascular disease (CVD). Hyperhomocysteinemia has also been associated with total and CVD mortality. However, whether Hcy is just a marker or plays a causal role in CVD remains to be elucidated. In this narrative review, we discuss the associations between Hcy and non-cardiac vascular diseases, namely stroke, peripheral artery disease (PAD), carotid artery disease, chronic kidney disease (CKD), atherosclerotic renal artery stenosis (ARAS), abdominal aortic aneurysm (AAA) and erectile dysfunction (ED)...
March 17, 2017: Current Pharmaceutical Design
https://www.readbyqxmd.com/read/28316038/the-impact-of-the-aortic-valve-impairment-on-the-distant-coronary-arteries-hemodynamics-a-fluid-structure-interaction-study
#3
Hossein Mohammadi, Raymond Cartier, Rosaire Mongrain
Atherosclerosis is still the leading cause of death in the developed world. Although its initiation and progression is a complex multifactorial process, it is well known that blood flow-induced wall shear stress (WSS) is an important factor involved in early atherosclerotic plaque initiation. In recent clinical studies, it was established that the regional pathologies of the aortic valve can be involved in the formation of atherosclerotic plaques. However, the impact of hemodynamic effects is not yet fully elucidated for disease initiation and progression...
March 18, 2017: Medical & Biological Engineering & Computing
https://www.readbyqxmd.com/read/28306749/cigarette-smoking-and-cardio-renal-events-in-patients-with-atherosclerotic-renal-artery-stenosis
#4
Christopher A Drummond, Pamela S Brewster, Wencan He, Kaili Ren, Yanmei Xie, Katherine R Tuttle, Steven T Haller, Kenneth Jamerson, Lance D Dworkin, Donald E Cutlip, Timothy P Murphy, Ralph B D'Agostino, William L Henrich, Jiang Tian, Joseph I Shapiro, Christopher J Cooper
Cigarette smoking causes cardiovascular disease and is associated with poor kidney function in individuals with diabetes mellitus and primary kidney diseases. However, the association of smoking on patients with atherosclerotic renal artery stenosis has not been studied. The current study utilized data from the Cardiovascular Outcomes in Renal Atherosclerotic Lesions (CORAL, NCT00081731) clinical trial to evaluate the effects of smoking on the risk of cardio-renal events and kidney function in this population...
2017: PloS One
https://www.readbyqxmd.com/read/28302657/vascular-challenges-from-pancreatoduodenectomy-in-the-setting-of-coeliac-artery-stenosis
#5
Joal D Beane, Roderich E Schwarz
Coeliac artery stenosis due to median arcuate ligament compression or atherosclerotic disease is a frequently unrecognised challenge to recovery after pancreatoduodenectomy. The described case illustrates management with intraoperative superior mesenteric artery to hepatic artery bypass graft that led to haemorrhagic challenges postoperatively but ultimately a good recovery. Aspects of preoperative diagnosis, preoperative intervention and intraoperative management options are reviewed. Surgeons need to possess these tools to prevent complications from coeliac artery stenosis when pancreatoduodenectomy is required...
March 16, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28299809/bedside-screening-with-the-use-of-pocket-size-imaging-device-can-be-useful-for-ruling-out-carotid-artery-stenosis-in-patients-scheduled-for-cardiac-surgery
#6
Dominika Filipiak-Strzecka, Jarosław D Kasprzak, Ewa Szymczyk, Paulina Wejner-Mik, Piotr Lipiec
BACKGROUND: Patients (pts) scheduled for coronary artery bypass grafting, burdened with high risk of carotid stenosis, are recommended to undergo duplex ultrasonography (DUS) of carotid arteries. PURPOSE: To validate pocket-size imaging device (PSID) equipped with linear probe as an easily accessible tool enabling bedside screening for carotid artery stenosis (CAS). METHODS: A total of 100 pts (60 men, mean age 69±11 years) with multivessel coronary artery disease underwent bedside DUS of carotid arteries with the use of PSID performed by a cardiology resident trained in DUS...
March 16, 2017: Echocardiography
https://www.readbyqxmd.com/read/28298048/carotid-atherosclerotic-plaque-instability-and-cognition-determined-by-ultrasound-measured-plaque-strain-in-asymptomatic-patients-with-significant-stenosis
#7
Robert J Dempsey, Tomy Varghese, Daren C Jackson, Xiao Wang, Nirvedh H Meshram, Carol C Mitchell, Bruce P Hermann, Sterling C Johnson, Sara E Berman, Stephanie M Wilbrand
OBJECTIVE This article describes the use of ultrasound measurements of physical strain within carotid atherosclerotic plaques as a measure of instability and the potential for vascular cognitive decline, microemboli, and white matter changes. METHODS Asymptomatic patients with significant (> 60%) carotid artery stenosis were studied for dynamic measures of plaque instability, presence of microemboli, white matter changes, and vascular cognitive decline in comparison with normative controls and premorbid state...
March 10, 2017: Journal of Neurosurgery
https://www.readbyqxmd.com/read/28297759/-expression-and-significance-of-integrin-%C3%AE-5%C3%AE-1-and-fibronectin-in-atherosclerotic-plaques-from-autopsy-specimens
#8
X Yu, Q Q Zhang, B Wang, L Sun
Objective: To investigate the expression of integrin α5β1 and fibronectin in the human aorta and coronary artery, and their effects in the development of atherosclerosis. Methods: One hundred and twenty autopsy aorta and coronary artery specimens were collected, and the expression of CD68, actin, integrin α5β1 and fibronectin was detected by immunohistochemical staining. Atherosclerotic plaques were located by CD68 and actin staining, and the degree of coronary artery stenosis was determined by elastic fiber staining and NIH Scion Image(60...
March 8, 2017: Zhonghua Bing Li Xue za Zhi Chinese Journal of Pathology
https://www.readbyqxmd.com/read/28290907/-combination-of-visual-and-metabolic-markers-in-assessment-of-probability-of-presence-and-severity-of-atherosclerosis-of-coronary-arteries
#9
V A Metelskaya, N E Gavrilova, N G Gumanova, O A Litinskaya, E B Yarovaya, S A Boytsov
AIM: to assess possibilities of the use of biochemical markers combined with data of methods of imaging of arterial atherosclerotic lesions for evaluation of risk of presence and severity of coronary atherosclerosis. MATERIALS AND METHODS: We enrolled into this study patients (n=205, 136 men, 69 women, age 33-85 years, 94% on statin therapy) who underwent coronary angiography and carotid artery ultrasound dopplerography. Examination included determination of parameters of lipid profile and carbohydrate metabolism, markers of inflammation and metabolism of visceral adipose tissue...
July 2016: Kardiologiia
https://www.readbyqxmd.com/read/28290832/-computed-tomography-in-the-evaluation-of-coronary-atherosclerotic-plaques-comparison-with-intravascular-ultrasound
#10
T N Veselova, M S Shabanova, V M Mironov, I N Merkulova, S K Ternovoy
PURPOSE: Determination of computed tomography angiography (CTA) informativeness in assessment of state of atherosclerotic coronary plaque (ACP) and identification of signs of its instability compared with intravascular ultrasound (IVUS). MATERIALS AND METHODS: Coronary CTA was carried out in 52 patients with clinical presentation of non-ST elevation (NSTE) acute coronary syndrome on the first day of hospitalization. ACPs were identified in 32 of 52 patients (61...
January 2017: Kardiologiia
https://www.readbyqxmd.com/read/28285408/essential-thrombocythemia-presenting-as-acute-coronary-syndrome-case-reports-and-literature-review
#11
Nanqing Xiong, Wen Gao, Junjie Pan, Xinping Luo, Haiming Shi, Jian Li
For the patients with essential thrombocythemia (ET), systemic thrombosis presents as one of the most dangerous complications. It's been widely accepted that acute coronary syndrome (ACS) is a kind of thrombotic diseases. However, there are very few case reports about ET first presenting as ACS. For some patients diagnosed as ACS, but without markedly elevated platelet, underlying ET was missed. And there are some controversies in the principles and target of treatment in those patients. We reported three cases of ACS, in which the patients who did not have common risk factors for coronary artery diseases and presented only mild atherosclerotic stenosis during coronary angiography, one of which had recurrent coronary artery thrombosis...
March 11, 2017: Journal of Thrombosis and Thrombolysis
https://www.readbyqxmd.com/read/28279437/coronary-plaque-characteristics-in-hemodialysis-dependent-patients-as-assessed-by-optical%C3%A2-coherence-tomography
#12
Chee Yang Chin, Mitsuaki Matsumura, Akiko Maehara, Wenbin Zhang, Cheolmin Tetsumin Lee, Myong Hwa Yamamoto, Lei Song, Yasir Parviz, Nisha B Jhalani, Sumit Mohan, Lloyd E Ratner, David J Cohen, Ori Ben-Yehuda, Gregg W Stone, Richard A Shlofmitz, Tsunekazu Kakuta, Gary S Mintz, Ziad A Ali
Coronary arteries in patients with chronic kidney disease (CKD) have been shown to exhibit more extensive atherosclerosis and calcium. We aimed to assess characteristics of coronary plaque in hemodialysis (HD)-dependent patients using optical coherence tomography (OCT). This was a multicenter, retrospective study of 124 patients with stable angina who underwent OCT imaging. Sixty-two HD-dependent patients who underwent pre-intervention OCT for coronary artery disease were compared 1:1 with a cohort of patients without CKD, matched for age, diabetes mellitus, gender, and culprit vessel...
February 9, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/28275418/sex-differences-of-the-natriuretic-peptide-polymorphism-associated-with-angiographic-coronary-atherosclerosis
#13
Terry Y Li, M Yat Tse, Stephen C Pang, Catherine S McLellan, Will D King, Amer M Johri
BACKGROUND: Polymorphisms within natriuretic peptide (NP) genes have been associated with clinical outcomes for cardiovascular disease (CVD), but no previous study has compared the effect of these polymorphisms between men and women. This study aimed to investigate the association between single nucleotide polymorphisms (SNPs) in key genes of the NP system and coronary angiographic outcomes, with the focus on the sexual dimorphism in the effects of these SNPs. METHODS: Patients undergoing clinically indicated coronary angiography (n = 513, 328 men and 185 women) were consented and genotyped for NPPA rs5065, NPPB rs198389 and NPR2 rs10758325...
February 2017: Cardiology Research
https://www.readbyqxmd.com/read/28270639/new-insights-into-pathophysiology-diagnosis-and-treatment-of-renovascular-hypertension
#14
Fariba Samadian, Nooshin Dalili, Ali Jamalian
Renovascular disease includes renal artery stenosis, renovascular hypertension, and azotemic renovascular disease (ischemic nephropathy). Renovascular hypertension is defined as an elevated blood pressure caused by renal hypoperfusion, usually resulting from anatomic stenosis of the renal artery and activation of the renin-angiotensin system. It accounts for 1% to 2 % of all cases of hypertension in the general population and 5.8 % of secondary hypertension, but it plays a major role in treatable causes of hypertension in the young individuals...
March 2017: Iranian Journal of Kidney Diseases
https://www.readbyqxmd.com/read/28268107/prosthetic-bypass-for-restenosis-after-endarterectomy-or-stenting-of-the-carotid-artery
#15
Giulio Illuminati, Romain Belmonte, Fabrice Schneider, Giulia Pizzardi, Francesco G Calió, Jean-Baptiste Ricco
OBJECTIVE: The objective of this study was to evaluate the results of prosthetic carotid bypass (PCB) with polytetrafluoroethylene (PTFE) grafts as an alternative to carotid endarterectomy (CEA) in treatment of restenosis after CEA or carotid artery stenting (CAS). METHODS: From January 2000 to December 2014, 66 patients (57 men and 9 women; mean age, 71 years) presenting with recurrent carotid artery stenosis ≥70% (North American Symptomatic Carotid Endarterectomy Trial [NASCET] criteria) were enrolled in a prospective study in three centers...
March 4, 2017: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/28257766/is-common-femoral-artery-stenosis-still-a-surgical-disease
#16
REVIEW
Stephan Heo, Peter Soukas, Herbert D Aronow
Surgical endarterectomy has long been the standard approach for treating atherosclerotic stenosis in the common femoral artery. Its major advantage is the associated long-term patency, which approaches 95% at 5 years. Nevertheless, recent studies have suggested that percutaneous treatment may be a valid alternative to surgery.
April 2017: Interventional cardiology clinics
https://www.readbyqxmd.com/read/28254161/long-term-results-of-endovascular-treatment-of-atherosclerotic-stenoses-or-occlusions-of-the-coeliac-and-superior-mesenteric-artery-in-patients-with-mesenteric-ischaemia
#17
T Bulut, R Oosterhof-Berktas, R H Geelkerken, M Brusse-Keizer, E J Stassen, J J Kolkman
INTRODUCTION: Over the past decade, primary percutaneous mesenteric artery stenting (PMAS) has become an alternative to open revascularisation for treatment of mesenteric ischaemia. Institutes have presented favourable short-term outcomes after PMAS, but there is a lack of data on long-term stent patency. METHODS: One hundred and forty-one patients treated by PMAS for acute and chronic mesenteric ischaemia over an 8 year period were studied. Anatomical success was assessed by duplex ultrasound and/or CT angiography...
February 18, 2017: European Journal of Vascular and Endovascular Surgery
https://www.readbyqxmd.com/read/28251333/recognizing-subtle-near-occlusion-in-carotid-stenosis-patients-a-computed-tomography-angiographic-study
#18
Suvi Maaria Koskinen, Heli Silvennoinen, Petra Ijäs, Krista Nuotio, Leena Valanne, Perttu J Lindsberg, Lauri Soinne
INTRODUCTION: Near-occlusion of the internal carotid artery (ICA) is a significant luminal diameter (LD) reduction beyond a tight atherosclerotic carotid stenosis (CS). Recognition of even subtle near-occlusions is essential to prevent underestimation of the stenosis degree. Our goal was to investigate the prevalence of near-occlusion among CS patients using a single standard criterion to facilitate its recognition, even when distal ICA LD reduction is not visually evident in computed tomography angiography (CTA)...
March 1, 2017: Neuroradiology
https://www.readbyqxmd.com/read/28249314/dual-energy-cta-in-patients-with-symptomatic-peripheral-arterial-occlusive-disease-study-of-diagnostic-accuracy-and-impeding-factors
#19
Thorsten Klink, Theresa Wilhelm, Christine Roth, Johannes T Heverhagen
Purpose The purpose of this study was to assess the diagnostic performance of dual-energy CT angiography (DE-CTA) in patients with symptomatic peripheral artery occlusive disease (PAOD) and to identify factors that impede its diagnostic accuracy. Materials and Methods Dual-source DE-CTA scans of the lower extremities of 94 patients were retrospectively compared to the diagnostic reference standard, digital subtraction angiography (DSA). Two independent observers assessed PAOD incidence, image quality, artifacts, and diagnostic accuracy of DE-CTA in 1014 arterial segments on axial, combined 80/140 kVp reconstructions and on 3 D maximum intensity projections (MIP) after automated bone and plaque removal...
March 1, 2017: RöFo: Fortschritte Auf Dem Gebiete der Röntgenstrahlen und der Nuklearmedizin
https://www.readbyqxmd.com/read/28242176/2017-taiwan-lipid-guidelines-for-high-risk-patients
#20
REVIEW
Yi-Heng Li, Kwo-Chang Ueng, Jiann-Shing Jeng, Min-Ji Charng, Tsung-Hsien Lin, Kuo-Liong Chien, Chih-Yuan Wang, Ting-Hsing Chao, Ping-Yen Liu, Cheng-Huang Su, Shih-Chieh Chien, Chia-Wei Liou, Sung-Chun Tang, Chun-Chuan Lee, Tse-Ya Yu, Jaw-Wen Chen, Chau-Chung Wu, Hung-I Yeh
In Taiwan, the prevalence of hyperlipidemia increased due to lifestyle and dietary habit changes. Low density lipoprotein cholesterol (LDL-C) and non-high density lipoprotein cholesterol (non-HDL-C) are all significant predicting factors of coronary artery disease in Taiwan. We recognized that lipid control is especially important in patients with existed atherosclerotic cardiovascular diseases (ASCVD), including coronary artery disease (CAD), ischemic stroke and peripheral arterial disease (PAD). Because the risk of ASCVD is high in patients with diabetes mellitus (DM), chronic kidney disease (CKD) and familial hypercholesterolemia (FH), lipid control is also necessary in these patients...
February 24, 2017: Journal of the Formosan Medical Association, Taiwan Yi Zhi
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