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https://www.readbyqxmd.com/read/29652746/fluorine-18-fluorodeoxyglucose-pet-ct-in-hematopoietic-stem-cell-transplant-patients-with-fusariosis-initial-findings-of-a-case-series-review
#1
Marcelo R Schirmer, Michel P Carneiro, Luiz S Machado, Alessandra L da S Chaves, Flávia P P L Lopes
BACKGROUND: Fusariosis is an opportunistic fungal infection that affects mostly leukemic and hematopoietic stem cell transplant patients. Locally invasive and disseminated infection may occur. Treatment is challenging, and besides evaluation of immune status, one also needs to take into account organ involvement to predict the duration and prognosis. OBJECTIVE: The aim of this study was to present the findings and clinical follow-up from a series of cases of Fusarium spp...
April 12, 2018: Nuclear Medicine Communications
https://www.readbyqxmd.com/read/29652439/evaluation-of-gaseous-allyl-isothiocyanate-against-the-growth-of-mycotoxigenic-fungi-and-mycotoxin-production-in-corn-stored-for-6-months
#2
Tiago M Nazareth, Jessica A F Corrêa, Anne C S M Pinto, Juliano B Palma, Giuseppe Meca, Keliani Bordin, Fernando B Luciano
BACKGROUND: Brazil produce approximately 63 million tons of corn kernels annually, which is commonly contaminated with fungi and mycotoxins. The objective of this study was to evaluate the efficacy of gaseous allyl isothiocyanate (AITC) to inhibit the growth of Aspergillus parasiticus and Fusarium verticillioides, and mycotoxin production (aflatoxins B1 , B2 , G1 and G2 , fumonisins B1 and B2 ) in corn during 180 d of storage. RESULTS: AITC at 50 μL L-1 resulted in a significant reduction of the fungal population (p <0...
April 13, 2018: Journal of the Science of Food and Agriculture
https://www.readbyqxmd.com/read/29651180/production-of-a-mixture-of-fengycins-with-surfactant-and-antifungal-activities-by-bacillus-sp-ma04-a-versatile-pgpr
#3
Alejandro Hernández-Morales, Ramón-Alvar Martínez-Peniche, Jackeline-Lizzeta Arvizu-Gómez, Sofía-María Arvizu-Medrano, Areli Rodríguez-Ontiveros, Miguel-Angel Ramos-López, Juan-Ramiro Pacheco-Aguilar
Bacillus sp. strain MA04 a plant growth-promoting rhizobacteria (PGPR) showed hemolytic activity on blood agar plates, and the supernatant from liquid culture in nutrient broth at 24 h exhibited emulsification activity, suggesting the production of biosurfactants. In antagonist assays, the supernatant showed antifungal activity against phytopathogenic fungi such as Penicillium expansum , Fusarium stilboides , Sclerotium rolfsii y Rhizoctonia solani , finding a reduction of mycelial growth of all fungi tested, ranging from 35 to 69%, this activity was increased with time of culture, accomplishing percentages of inhibition up to 85% with supernatants obtained at 72 h...
June 2018: Indian Journal of Microbiology
https://www.readbyqxmd.com/read/29651174/identification-and-pathogenicity-of-fungal-pathogens-causing-black-point-in-wheat-on-the-north-china-plain
#4
Kai-Ge Xu, Yu-Mei Jiang, Yang-Kun Li, Qiao-Qiao Xu, Ji-Shan Niu, Xin-Xin Zhu, Qiao-Yun Li
Fungi associated with black point were isolated from three highly susceptible wheat genotypes in the North China Plain. The 21 isolates represented 11 fungal genera. The most prevalent genera were Alternaria (isolation frequency of 56.7%), Bipolaris (16.1%), and Fusarium (6.0%). The other eight genera were Curvularia , Aspergillus , Cladosporium , Exserohilum , Epicoccum , Nigrospora , Penicillium , and Ulocladium ; their isolation frequencies ranged from 0.8 to 4.8%. The pathogenicity of the isolates was individually assessed in the greenhouse by inoculating wheat plants with spore suspensions...
June 2018: Indian Journal of Microbiology
https://www.readbyqxmd.com/read/29651009/diversity-and-bioactive-potential-of-culturable-fungal-endophytes-of-dysosma-versipellis-a-rare-medicinal-plant-endemic-to-china
#5
Xiaoming Tan, Yaqin Zhou, Xiaolei Zhou, Xianghua Xia, Ying Wei, Lili He, Hongzhen Tang, Liyin Yu
The plant Dysosma versipellis is known for its antimicrobial and anticancer properties but is a rare and vulnerable perennial herb that is endemic to China. In this study, 224 isolates were isolated from various tissues of D. versipellis, and were classified into 53 different morphotypes according to culture characteristics and were identified by sequence analyses of the internal transcribed spacer (ITS) region of the rRNA gene. Although nine strains were not assignable at the phylum level, 44 belonged to at least 29 genera of 15 orders of Ascomycota (93%), Basidiomycota (6%), and Zygomycota (1%)...
April 12, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29650464/clioquinol-an-alternative-antimicrobial-agent-against-common-pathogenic-microbe
#6
Z You, X Ran, Y Dai, Y Ran
Skin and soft tissue infections (SSTIs) are very common in dermatology and the use of antimicrobial formulations are important in treating these diseases. With the increasing of drug-resistant strains, researchers need to find ways to enhance the effectiveness and/or reduce the drug resistance. Clioquinol was one of antiseptics that can inactivate microbes. It was lack of data of antimicrobial activity; meanwhile it was infrequently used in infection. In order to research the antimicrobial spectrum and activity of topical 3% clioquinol cream among common pathogenic microorganisms compared with other common topical pharmaceuticals, we used modified agar diffusion assay to judge drug susceptibility and compared with broth microdilution assay...
April 10, 2018: Journal de Mycologie Médicale
https://www.readbyqxmd.com/read/29649280/evolution-of-structural-diversity-of-trichothecenes-a-family-of-toxins-produced-by-plant-pathogenic-and-entomopathogenic-fungi
#7
Robert H Proctor, Susan P McCormick, Hye-Seon Kim, Rosa E Cardoza, April M Stanley, Laura Lindo, Amy Kelly, Daren W Brown, Theresa Lee, Martha M Vaughan, Nancy J Alexander, Mark Busman, Santiago Gutiérrez
Trichothecenes are a family of terpenoid toxins produced by multiple genera of fungi, including plant and insect pathogens. Some trichothecenes produced by the fungus Fusarium are among the mycotoxins of greatest concern to food and feed safety because of their toxicity and frequent occurrence in cereal crops, and trichothecene production contributes to pathogenesis of some Fusarium species on plants. Collectively, fungi produce over 150 trichothecene analogs: i.e., molecules that share the same core structure but differ in patterns of substituents attached to the core structure...
April 2018: PLoS Pathogens
https://www.readbyqxmd.com/read/29642627/a-review-of-the-interactions-between-wheat-and-wheat-pathogens-zymoseptoria-tritici-fusarium-spp-and-parastagonospora-nodorum
#8
REVIEW
Adrian Duba, Klaudia Goriewa-Duba, Urszula Wachowska
Zymoseptoria tritici is a hemibiotrophic pathogen which causes Septoria leaf blotch in wheat. The pathogenesis of the disease consists of a biotrophic phase and a necrotrophic phase. The pathogen infects the host plant by suppressing its immune response in the first stage of infection. Hemibiotrophic pathogens of the genus Fusarium cause Fusarium head blight, and the necrotrophic Parastagonospora nodorum is responsible for Septoria nodorum blotch in wheat. Cell wall-degrading enzymes in plants promote infections by necrotrophic and hemibiotrophic pathogens, and trichothecenes, secondary fungal metabolites, facilitate infections caused by fungi of the genus Fusarium ...
April 10, 2018: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/29629650/fusarium-keratoplasticum-infection-in-an-hiv-infected-patient
#9
Alice Annalisa Medaglia, Javier Marco-Hernández, José Tomás de Ossó Acuña, Evelyn Hermida Lama, María Martínez-Rebollar, Miguel Caballero, Leonardo Rodríguez-Carunchio, Felipe García
Fusarium infections are very rare in HIV-infected patients, even in patients in advanced stages of immunosuppression. All the reported cases in the literature are of disseminated infection, and with poor outcomes despite prompt and appropriate treatment. To the best of our knowledge, this is the first report of a localized infection with Fusarium keratoplasticum in an HIV-positive patient, successfully treated with a combination of antifungal therapy and surgical removal of the focus.
January 1, 2018: International Journal of STD & AIDS
https://www.readbyqxmd.com/read/29628225/synthesis-characterization-and-antifungal-evaluation-of-diethoxyphosphoryl-polyaminoethyl-chitosan-derivatives
#10
Zhaoqian Fan, Yukun Qin, Song Liu, Ronge Xing, Huahua Yu, Xiaolin Chen, Kecheng Li, Pengcheng Li
Botrytis cinerea, Phytophthora capsici Leonian, and Fusarium solani are important plant pathogenic fungi which can cause great crop losses worldwide, but their control methods are limited. It is necessary to develop efficient and green fungicides from abundant marine resources. Chitosan is a non-toxic, biodegradable, biocompatible marine polysaccharide which has prospective applications in agriculture. In this paper, to increase the antifungal activity of chitosan for application, novel water-soluble functional chitosan derivatives were synthesized by grafting polyaminoethyl and diethoxyphosphoryl groups in accordance with a strategy of improving protonation potential...
June 15, 2018: Carbohydrate Polymers
https://www.readbyqxmd.com/read/29627901/microbiological-quality-of-air-in-free-range-and-box-stall-stable-horse-keeping-systems
#11
Katarzyna Wolny-Koładka
The aim of this study was to assess the microbiological quality of air in three horse riding centers differing in the horse keeping systems. The air samples were collected in one facility with free-range horse keeping system and two with box stalls of different sizes. The samples were collected over a period of 3 years (2015-2017), four times per year (spring, summer, autumn, winter) to assess the effect of seasonal changes. The prevalence of aerobic mesophilic bacteria, mold fungi, actinomycetes, Staphylococcus spp...
April 7, 2018: Environmental Monitoring and Assessment
https://www.readbyqxmd.com/read/29625485/atovaquone-impairs-growth-of-aspergillus-and-fusarium-keratitis-isolates-by-modulating-mitochondrial-function-and-zinc-homeostasis
#12
Heather L Clark, Martin S Minns, Yan Sun, Tristan de Jesus, Mahmoud G Ghannoum, Eric Pearlman
Purpose: Aspergillus and Fusarium molds cause blinding corneal infections as a consequence of ocular trauma and in association with contact lens wear. As these fungi require zinc for fungal growth, we examined the effect of atovaquone, a ubiquinone analog that disrupts zinc homeostasis, on fungal growth in vitro and in vivo. Methods: In vitro: Aspergillus and Fusarium germinating conidia were incubated overnight with atovaquone, and hyphal growth was measured by fluorimetry...
March 1, 2018: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/29625221/synthesis-characterization-and-antifungal-efficacy-of-chitosan-derivatives-with-triple-quaternary-ammonium-groups
#13
Weixiang Liu, Yukun Qin, Song Liu, Ronge Xing, Huahua Yu, Xiaolin Chen, Kecheng Li, Pengcheng Li
A novel type of water soluble chitosan derivatives (TQCSPX) were synthesized including 3-aminopyridine (TQCSP1) and 3-Amino-4-methylpyridine (TQCSP2). The theoretical structures of TQCSPX were calculated by Gaussian 09 and confirmed by FT-IR,1 H NMR,13 C NMR, elemental analysis and XRD. The antifungal properties of TQCSPX against Phytophthora capsici (P. capsici), Rhizoctonia solani (R. solani), Fusarium oxysporum (F. oxysporum) and Fusarium solani (F. solani) were evaluated at concentrations ranging from 0...
April 3, 2018: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/29622705/native-valve-endocarditis-fusarium-and-end-stage-renal-disease
#14
Supradip Ghosh, Atul Phillips, Sonali Ghosh, Amandeep Singh
We would like to report a case of invasive Fusariosis involving the native mitral valve and complicated by septic thromboembolism. The patient was a known case of end-stage renal disease on maintenance haemodialysis and did not have any of the known risk factors for invasive Fusariosis like neutropaenia, severe T cell immunodeficiency, postsolid organ transplant recipients, posthaematopoietic stem cell transplant recipients and patients who received cytotoxic and/or high-dose corticosteroid therapy.
April 5, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29621291/fungal-community-profiles-in-agricultural-soils-of-a-long-term-field-trial-under-different-tillage-fertilization-and-crop-rotation-conditions-analyzed-by-high-throughput-its-amplicon-sequencing
#15
Loreen Sommermann, Joerg Geistlinger, Daniel Wibberg, Annette Deubel, Jessica Zwanzig, Doreen Babin, Andreas Schlüter, Ingo Schellenberg
Fungal communities in agricultural soils are assumed to be affected by soil and crop management. Our intention was to investigate the impact of different tillage and fertilization practices on fungal communities in a long-term crop rotation field trial established in 1992 in Central Germany. Two winter wheat fields in replicated strip-tillage design, comprising conventional vs. conservation tillage, intensive vs. extensive fertilization and different pre-crops (maize vs. rapeseed) were analyzed by a metabarcoding approach applying Illumina paired-end sequencing of amplicons generated by two recently developed primer pairs targeting the two fungal Internal Transcribed Spacer regions (ITS1, ITS2)...
2018: PloS One
https://www.readbyqxmd.com/read/29619233/vegan-mycoprotein-concentrate-from-pea-processing-industry-byproduct-using-edible-filamentous-fungi
#16
Pedro F Souza Filho, Ramkumar B Nair, Dan Andersson, Patrik R Lennartsson, Mohammad J Taherzadeh
Background: Currently around one billion people in the world do not have access to a diet which provides enough protein and energy. However, the production of one of the main sources of protein, animal meat, causes severe impacts on the environment. The present study investigates the production of a vegan-mycoprotein concentrate from pea-industry byproduct (PpB), using edible filamentous fungi, with potential application in human nutrition. Edible fungal strains of Ascomycota ( Aspergillus oryzae , Fusarium venenatum , Monascus purpureus , Neurospora intermedia ) and Zygomycota ( Rhizopus oryzae ) phyla were screened and selected for their protein production yield...
2018: Fungal Biology and Biotechnology
https://www.readbyqxmd.com/read/29616057/the-polycistronic-mir166k-166h-positively-regulates-rice-immunity-via-post-transcriptional-control-of-ein2
#17
Raquel Salvador-Guirao, Yue-Ie Hsing, Blanca San Segundo
MicroRNAs (miRNAs) are small RNAs acting as regulators of gene expression at the post-transcriptional level. In plants, most miRNAs are generated from independent transcriptional units, and only a few polycistronic miRNAs have been described. miR166 is a conserved miRNA in plants targeting the HD-ZIP III transcription factor genes. Here, we show that a polycistronic miRNA comprising two miR166 family members, miR166k and miR166h, functions as a positive regulator of rice immunity. Rice plants with activated MIR166k-166h expression showed enhanced resistance to infection by the fungal pathogens Magnaporthe oryzae and Fusarium fujikuroi , the causal agents of the rice blast and bakanae disease, respectively...
2018: Frontiers in Plant Science
https://www.readbyqxmd.com/read/29614397/heterologous-expression-and-antimicrobial-activity-of-osgasr3-from-rice-oryza-sativa-l
#18
Krissana Boonpa, Supaluk Tantong, Kamonwan Weerawanich, Pawinee Panpetch, Onanong Pringsulaka, Yodying Yingchutrakul, Sittiruk Roytrakul, Supaart Sirikantaramas
According to an in silico analysis, OsGASR3 (LOC_Os03g55290) from rice (Oryza sativa L.) was predicted to be involved in plant defense mechanisms. A semi-quantitative reverse transcription polymerase chain reaction assay revealed that OsGASR3 is highly expressed in the inflorescences of Thai jasmine rice (O. sativa L. subsp. indica 'KDML 105'). To characterize the biological activity of OsGASR3, we produced an OsGASR3-glutathione S-transferase fusion protein in Escherichia coli Rosetta-gami (DE3) cells for a final purified recombinant OsGASR3 yield of 0...
March 27, 2018: Journal of Plant Physiology
https://www.readbyqxmd.com/read/29614031/role-of-phenolic-acids-from-the-rhizosphere-soils-of-panax-notoginseng-as-a-double-edge-sword-in-the-occurrence-of-root-rot-disease
#19
Ya-Meng Zhao, Yong-Xian Cheng, Yu-Nan Ma, Chuan-Jiao Chen, Fu-Rong Xu, Xian Dong
Chemical agents in the rhizosphere soils of plants might have an influence on root-rot disease, which therefore might reveal the mechanism of root rot in Panax notoginseng ( P. notoginseng ). With this hypothesis the alterations of phenolic acids (PAs) in the rhizosphere soils of P. notoginseng after pathogen infection were determined. The effects of PAs on the growth of Fusarium oxysporum ( F. oxysporum ), a fungal pathogenic factor for P. notoginseng , as well as production of fusaric acid, a wilting agent for the plants, were also examined...
April 3, 2018: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/29611633/deoxynivalenol-as-potential-modulator-of-human-steroidogenesis
#20
REVIEW
Kinga Anna Urbanek, Dominika Ewa Habrowska-Górczyńska, Karolina Kowalska, Anna Stańczyk, Kamila Domińska, Agnieszka Wanda Piastowska-Ciesielska
Deoxynivalenol (DON) is a type B trichothecene, produced by the Fusarium species. Exposure to DON might cause disruptive effects such as reduced weight gain, neuroendocrine changes and immune modulation in animals (rats, dogs, pigs). There is huge concern that similar effects can be observed in humans. DON is a potential regulator of intracellular steroidogenesis. It is also possible that DON will be involved in the regulation of miRNAs connected with steroidogenesis. This review summarizes the latest knowledge about the influence of DON on steroidogenesis and human hormonal balance...
April 3, 2018: Journal of Applied Toxicology: JAT
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