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Geoffrey H Tison, José M Sanchez, Brandon Ballinger, Avesh Singh, Jeffrey E Olgin, Mark J Pletcher, Eric Vittinghoff, Emily S Lee, Shannon M Fan, Rachel A Gladstone, Carlos Mikell, Nimit Sohoni, Johnson Hsieh, Gregory M Marcus
Importance: Atrial fibrillation (AF) affects 34 million people worldwide and is a leading cause of stroke. A readily accessible means to continuously monitor for AF could prevent large numbers of strokes and death. Objective: To develop and validate a deep neural network to detect AF using smartwatch data. Design, Setting, and Participants: In this multinational cardiovascular remote cohort study coordinated at the University of California, San Francisco, smartwatches were used to obtain heart rate and step count data for algorithm development...
March 21, 2018: JAMA Cardiology
Bhavik N Modi, Kalpa De Silva, Ronak Rajani, Nick Curzen, Divaka Perera
Importance: Ischemia-guided revascularization is the cornerstone of contemporary management of coronary artery disease and has evolved from noninvasive functional evaluation to real-time assessment with invasive physiological indices during diagnostic catheterization. However, serial/diffuse disease is common, and revascularization decisions often need to be made about individual lesions within the same vessel. It is unclear whether current physiological techniques, such as fractional flow reserve, can be reliably used to discern the individual contribution of lesions within a serially diseased vessel with erroneous measurements, potentially leading to suboptimal revascularization decisions...
March 21, 2018: JAMA Cardiology
Nico E Knibbe, Elien Zwaenepoel, Hanneke Jj Knibbe, Dimitri Beeckman
The Danish automated Vendlet V5s repositioning system is intended to reduce pressure ulcer risk in patients and work-related musculoskeletal disorders (MSDs) in caregivers. In two Belgian nursing homes, 13 residents with mobility levels C, D and E experienced the repositioning system, operated by 35 caregivers, for 4 weeks. Data about skin condition, nursing time needed for repositioning and MSD symptoms were collected. The use of the repositioning system was not associated with the development of nor a reduction in skin problems; the study included residents who were vulnerable to or already had pressure ulcers...
March 22, 2018: British Journal of Nursing: BJN
Eran Ben-Arye, Yaron River, Yael Keshet, Ofer Lavie, Pesi Israeli L, Noah Samuels
OBJECTIVE: Peripheral neuropathy is a common complication of cancer treatment impairing quality of life and function. This study explored the impact of a complementary and integrative medicine (CIM) program on taxane-induced peripheral neuropathy (TIPN). MATERIALS AND METHODS: Taxane-treated female patients with breast and gynecological cancer reporting TIPN-related symptoms were referred to an integrative physician, followed by patient-tailored CIM treatments (acupuncture with/without other modalities)...
March 21, 2018: International Journal of Gynecological Cancer
Shailesh M Gondivkar, Amol R Gadbail, Rima S Gondivkar, Sachin C Sarode, Gargi S Sarode, Shankargouda Patil
Although oral potentially malignant disorders (OPMDs) are relatively common and potentially debilitating, literature on quality of life (QoL) in these patients is scanty. The purpose of this paper is to systematically review the literature on QoL in patients with OPMDs. A total of 210 titles were retrieved from electronic and manual databases searched from 1960 until September 2017. Out of these, 25 met our strict inclusion criteria as per the preferred reporting items for systematic reviews and meta-analyses guidelines...
March 21, 2018: Future Oncology
Ozge Dokuzlar, Pinar Soysal, Cansu Usarel, Ahmet Turan Isik
INTRODUCTION: Depression is a common and serious healthcare problem for older adults. This study aimed to determine the validity and reliability of GDS-4 and GDS-5 in Turkish, and to establish a new short-form Geriatric Depression Scale (GDS) for our population, and also determine the superiority of each short scale to another. METHODS: A total of 437 outpatients were enrolled in the study. A researcher evaluated all participants according to the Diagnostic and Statistical Manual of Mental Disorders-fifth edition (DSM-5) diagnostic criteria, and then another researcher applied GDS-15 to all participants...
March 21, 2018: International Psychogeriatrics
Pierre H M Pechon, Rhys Pullin, Mark J Eaton, Stephan A Jones, Sam Evans
During uncemented hip arthroplasty the femoral prosthesis can be fitted too tightly into the femoral canal, causing a hoop-stress fracture of the proximal femur. The research undertaken evaluated Acoustic Emission (AE) technology as a potential method of detecting a fracture forming in this manner, in an attempt to assess whether this technology may be used as a means of early warning of impending fracture during surgery. Deer femora were prepared in a manner similar to surgery and uncemented hip arthroplasty broaches were inserted until fracture occurred...
March 21, 2018: Journal of Medical Engineering & Technology
G Tsoucalas, T G Papaioannou, G V Papatheodoridis, M Karamanou
Known since antiquity, rectal prolapse was first studied systematically by Hippocrates (460-377 BC) who recognized the predisposing factors and proposed several therapeutic approaches such as defecation positions, manual retraction and specific herbal or mineral based anti-haemorrhagic and pain-killing poultices. Hippocratic medicine avoided invasive surgical procedures probably due to a lack of knowledge in human anatomy. However, Hippocrates' views astonishingly lasted in time, presenting similarities to current medical theories on rectal prolapse...
July 2017: Acta Gastro-enterologica Belgica
Junedh M Amrute, Lambros S Athanasiou, Farhad Rikhtegar, José M de la Torre Hernández, Tamara García Camarero, Elazer R Edelman
Polymeric endovascular implants are the next step in minimally invasive vascular interventions. As an alternative to traditional metallic drug-eluting stents, these often-erodible scaffolds present opportunities and challenges for patients and clinicians. Theoretically, as they resorb and are absorbed over time, they obviate the long-term complications of permanent implants, but in the short-term visualization and therefore positioning is problematic. Polymeric scaffolds can only be fully imaged using optical coherence tomography (OCT) imaging-they are relatively invisible via angiography-and segmentation of polymeric struts in OCT images is performed manually, a laborious and intractable procedure for large datasets...
March 2018: Journal of Biomedical Optics
Roxanne Saucier, Daniel Wolfe, Nabarun Dasgupta
INTRODUCTION: An extended-release injectable naltrexone suspension (Vivitrol® ) was approved in USA in 2010 for the prevention of relapse to opioid dependence. Concerns, raised at the time of approval, about rebound overdose risk following the last dose, have not been adequately studied. We sought to determine the time period of concern for fatal overdose associated with Vivitrol. METHODS: We performed a retrospective case review of Vivitrol spontaneous reports (October 2010-March 2016) in the US Food and Drug Administration Adverse Event Reporting System via the Freedom of Information Act...
March 20, 2018: Drug Safety: An International Journal of Medical Toxicology and Drug Experience
Jennifer L Walton, Diane K Dunn, Nhi Y Haines, Ilana Heisler, Michael T Bigham, Teresa A Volsko
BACKGROUND: The American Academy of Pediatrics Section on Transport recommends the use of portable ventilators during the transport of patients with advanced airways. We sought to identify knowledge gaps and evaluate the effectiveness of a transport ventilator competency boot camp. METHODS: Electronic health records of children requiring ventilatory support during air and ground interfacility transport from January 1 through December 31, 2015, were reviewed to determine when manual ventilation was used in lieu of a portable ventilator, and simulations were constructed from commonly occurring scenarios...
March 20, 2018: Respiratory Care
Yu-Ting Tseng, Chia-Liang Tsai, Fu-Chen Chen, Jürgen Konczak
This study obtained objective measures of wrist position sense to verify that children with DCD have proprioceptive deficits. In addition, it examined the relationship of wrist proprioceptive impairment with fine motor and balance function. Twenty children with DCD and thirty typically developing children (TD) aged 10-11 years old were recruited and screened using the Movement Assessment Battery for Children (MABC-2). The DCD group had total MABC-2 score below 5th percentile, and TD group was above 25th percentile...
March 17, 2018: Neuroscience Letters
Carlos E Cardenas, Rachel E McCarroll, Laurence E Court, Baher A Elgohari, Hesham Elhalawani, Clifton D Fuller, Mona J Kamal, Mohamed A M Meheissen, Abdallah S R Mohamed, Arvind Rao, Bowman Williams, Andrew Wong, Jinzhong Yang, Michalis Aristophanous
PURPOSE: Automating and standardizing the contouring of clinical target volumes (CTVs) can reduce interphysician variability, which is one of the largest sources of uncertainty in head and neck radiation therapy. In addition to using uniform margin expansions to auto-delineate high-risk CTVs, very little work has been performed to provide patient- and disease-specific high-risk CTVs. The aim of the present study was to develop a deep neural network for the auto-delineation of high-risk CTVs...
February 7, 2018: International Journal of Radiation Oncology, Biology, Physics
Mathew J Tomlinson, Asad Naeem
CASA has been used in reproductive medicine and pathology laboratories for over 25 years, yet the 'fertility industry' generally remains sceptical and has avoided automation, despite clear weaknesses in manual semen analysis. Early implementers had difficulty in validating CASA-Mot instruments against recommended manual methods (haemocytometer) due to the interference of seminal debris and non-sperm cells, which also affects the accuracy of grading motility. Both the inability to provide accurate sperm counts and a lack of consensus as to the value of sperm kinematic parameters appear to have continued to have a negative effect on CASA-Mot's reputation...
March 21, 2018: Reproduction, Fertility, and Development
Yoshihiro Ueda, Jun-Ichi Fukunaga, Tatsuya Kamima, Yumiko Adachi, Kiyoshi Nakamatsu, Hajime Monzen
BACKGROUND: The aim of this study was to evaluate the performance of a commercial knowledge-based planning system, in volumetric modulated arc therapy for prostate cancer at multiple radiation therapy departments. METHODS: In each institute, > 20 cases were assessed. For the knowledge-based planning, the estimated dose (ED) based on geometric and dosimetric information of plans was generated in the model. Lower and upper limits of estimated dose were saved as dose volume histograms for each organ at risk...
March 20, 2018: Radiation Oncology
Daniel V Gaz, Thomas M Rieck, Nolan W Peterson, Jennifer A Ferguson, Darrell R Schroeder, Heather A Dunfee, Jill M Henderzahs-Mason, Philip T Hagen
PURPOSE: Clinicians and fitness professionals are increasingly recommending the use of activity trackers. This study compares commercially available activity tracking devices for step and distance accuracy in common exercise settings. DESIGN: Cross sectional. SETTING: Rochester, Minnesota. PARTICIPANTS: Thirty-two men (n = 10) and women (n = 22) participated in the study. MEASURES: Researchers manually counted steps and measured distance for all trials, while participants wore 6 activity tracking devices that measured steps and distance...
January 1, 2018: American Journal of Health Promotion: AJHP
Tobias M R Houlton, Caroline Wilkinson
Shrunken heads are a mummification phenomenon unique to South America. Ceremonial tsantsa are ritually reduced heads from enemy victims of the Shuar, Achuar, Awajún (Aguaruna), Wampís (Huambisa), and Candoshi-Shapra cultures. Commercial shrunken heads are comparatively modern and fraudulently produced for the curio-market, often using stolen bodies from hospital mortuaries and graves. To achieve shrinkage and desiccation, heads undergo skinning, simmering (in water) and drying. Considering the intensive treatments applied, this research aims to identify how the facial structure can alter and impact identification using post-mortem depiction...
March 6, 2018: Forensic Science International
Alison D Kissling, Kimberly D Ballinger
Faculty publications have been collected in universities, health, and medical institutions for many years, and Cincinnati Children's is no exception. Since 1949, a yearly list of faculty publications was manually compiled using multiple data sources and disseminated by the Edward L. Pratt Research Library. Products to centralize faculty publication collection and analysis with bibliometric tools are growing in popularity. This article will review the collaborative decision to choose a Research Information Management System and the implementation process including successes, challenges, and future opportunities...
April 2018: Medical Reference Services Quarterly
James T Eckner, Alireza Goshtasbi, Kayla Curtis, Aliaksandra Kapshai, Erik Myyra, Lea M Franco, Michael Favre, Jon A Jacobson, James A Ashton-Miller
Greater neck girth and strength may be associated with a lower risk of sport-related concussion due to mitigation of head accelerations by the neck. However, neck strengthening exercise remains unstudied in youth athletes. Therefore, this pilot study assessed the feasibility and effect of targeted neck strengthening exercises in youth athletes. Seventeen participants were allocated to perform 8-wk manual resistance-based neck strengthening (n = 13) or control resistance exercise (n = 4) programs. Before and after the intervention, participants completed laboratory-based assessments of neck size, strength, and head kinematics during standardized test loading in each plane of motion...
April 2018: American Journal of Physical Medicine & Rehabilitation
Kristina Griffin, Michael O'Hearn, Carla C Franck, Carol A Courtney
STUDY DESIGN: Case Report. PURPOSE: Stroke is the most common cause of long-term disability. Dysesthesia, an unpleasant sensory disturbance, is common following thalamic stroke and evidence-based interventions for this impairment are limited. The purpose of this case report was to describe a decrease in dysesthesia following manual therapy intervention in a patient with history of right lacunar thalamic stroke. CASE DESCRIPTION: A 66-year-old female presented with tingling and dysesthesia in left hemisensory distribution including left trunk and upper/lower extremities, limiting function...
March 20, 2018: Disability and Rehabilitation
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