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high reliability organization

Marian Suarez-Escobar, Elizabeth Rendon-Velez
PURPOSE: This article aims to clarify the current state-of-the-art of robotic/mechanical devices for post-stroke thumb rehabilitation as well as the anatomical characteristics and motions of the thumb that are crucial for the development of any device that aims to support its motion. METHODS: A systematic literature search was conducted to identify robotic/mechanical devices for post-stroke thumb rehabilitation. Specific electronic databases and well-defined search terms and inclusion/exclusion criteria were used for such purpose...
January 15, 2018: Disability and Rehabilitation. Assistive Technology
Sunita Arora, Manju Saini
Background: Corbichonia decumbens (Forssk.) Exell (Molluginaceae), recently has moved to Lophiocarpaceae as per angiospermic plant group (APG) III system, is an annual or short-lived, dwarf, glabrous subshrub, prefers to grow on rocky places and on sand-stones in dry, hot areas of Rajasthan. This is the potential plant with medicinal properties. Vegetative organs under study show antioxidant, anti-inflammatory, antiulcer, antimicrobial, and antinociception activity. Objective: This study was carried out to identify the phytoconstituents present in the methanolic and ethyl-acetate extract of root and stem of C...
December 2017: Pharmacognosy Research
Preethi Seshadri, Kyriaki Manoli, Nicole Schneiderhan-Marra, Uwe Anthes, Piotr Wierzchowiec, Klaus Bonrad, Cinzia Di Franco, Luisa Torsi
Herein a label-free immunosensor based on electrolyte-gated organic field-effect transistor (EGOFET) was developed for the detection of procalcitonin (PCT), a sepsis marker. Antibodies specific to PCT were immobilized on the poly-3-hexylthiophene (P3HT) organic semiconductor surface through direct physical adsorption followed by a post-treatment with bovine serum albumin (BSA) which served as the blocking agent to prevent non-specific adsorption. Antibodies together with BSA (forming the whole biorecognition layer) served to selectively capture the procalcitonin target analyte...
December 26, 2017: Biosensors & Bioelectronics
Chandra H McAllister, Colleen E Fortier, Kate R St Onge, Bianca M Sacchi, Meaghan J Nawrot, Troy Locke, Janice E K Cooke
Mountain pine beetle (Dendroctonus ponderosae Hopkins; MPB) is an economically and ecologically important pest of pine species in western North America. Mountain pine beetles form complex multipartite relationships with microbial partners, including the ophiostomoid fungi Grosmannia clavigera (Robinson-Jeffrey and Davidson) Zipfel, de Beer and Wingfield, Ophiostoma montium (Rumbold) von Arx, Grosmannia aurea (Robinson-Jeffrey and Davidson) Zipfel, de Beer and Wingfield, Leptographium longiclavatum (Lee, Kim, and Breuil) and Leptographium terebrantis (Barras and Perry)...
January 10, 2018: Tree Physiology
Ryeo-Ok Kim, Min-A Jo, Jinhaeng Song, Il-Chan Kim, Seokjoo Yoon, Woo-Keun Kim
Because of its widespread use, the pharmaceutical acetaminophen (APAP) is frequently detected in aquatic environments. APAP can have serious physiological effects, such as reduced reproduction, low growth rates, and abnormal behavior, in aquatic organisms. However, the methods available for evaluation of the aquatic toxicity of APAP are of limited usefulness. The present study aimed to develop reliable and sensitive markers for evaluation of APAP toxicity using Daphnia as a model organism. We focused on N-acetyl-p-benzoquinoneimine (NAPQI) production from APAP via cytochrome P450 metabolism because NAPQI causes APAP toxicity...
December 30, 2017: Aquatic Toxicology
Michael Chys, Wim T M Audenaert, Jan Vangrinsven, Michael Bauwens, Séverine T F C Mortier, Herman Van Langenhove, Ingmar Nopens, Kristof Demeestere, Stijn W H Van Hulle
New robust correlation models for ozonation, based on UVA254 and fluorescence surrogate parameters and developed considering kinetic information, have been applied at pilot-scale. This model framework is validated with the aim for operators to control the ozone dose for the removal of trace organic contaminants (TrOCs) in effluents from full-scale municipal wastewater treatment plants. The inflected correlation model between ΔTrOCs and the surrogates predicts the removal of TrOCs (based on statistical evidence) solely using the 2nd order reaction rate constant with ozone (kO3) and in a more adequate manner than similar single correlation models...
December 27, 2017: Chemosphere
Dimitri Berh, Aaron Scherzinger, Nils Otto, Xiaoyi Jiang, Christian Klämbt, Benjamin Risse
The importance of studying model organisms such as Drosophila melanogaster has significantly increased in recent biological research. Amongst others, Drosophila can be used to study heart development and heartbeat related diseases. Here we propose a method for automatic in vivo heartbeat detection of Drosophila melanogaster pupae based on morphological structures which are recorded without any dissection using FIM imaging. Our approach is easy-to-use, has low computational costs, and enables high-throughput experiments...
December 29, 2017: Computers in Biology and Medicine
Michael Chua, Jessica Ming, Shang-Jen Chang, Joana Dos Santos, Niraj Mistry, Jan Michael Silangcruz, Mark Bayley, Martin Koyle
INTRODUCTION: Concerns regarding the quality, credibility, and applicability of recently published pediatric urinary tract infection (UTI) clinical practice guidelines have been raised due to the inconsistencies of recommendations between them. We aimed to determine the quality of the recent clinical practice guidelines on pediatric UTI by using the Appraisal of Guidelines Research and Evaluation (AGREE II) instrument, and summarize the standard of care in diagnosis and management of pediatric UTI from the top three clinical practice guidelines...
December 22, 2017: Canadian Urological Association Journal, Journal de L'Association des Urologues du Canada
Bangguo Peng, Jiewu Cui, Yan Wang, Jiaqin Liu, Hongmei Zheng, Li Jin, Xinyi Zhang, Yong Zhang, Yucheng Wu
Developing suitable substrate materials is of significance in constructing electrochemical biosensors for fast and reliable quantification of molecules of chemical and biomedical interest. For practical applications, biosensors working at low negative potentials have the advantage of high selectivity and sensitivity. In this work, CeO2-x/C/rGO nanocomposites have been synthesized through the pyrolysis of metal organic frameworks with graphene oxide. The CeO2-x/C/rGO nanocomposites exhibit excellent catalytic properties towards H2O2, which is one of the uricase catalyzed intermediates at low working potentials due to the coexistence of Ce3+ and reduced graphene oxide (rGO)...
January 10, 2018: Nanoscale
Seyed Mohammad Hadi Mousavi, Mahmoud Jabbarvand Behrouz, Hojjat Zerati, Hossein Dargahi, Akram Asadollahi, Seyed Ahmad Mousavi, Elham Ashrafi, Abolfazl Aliyari
Background: A high-reliability organization (HRO) is a separate paradigm can indicate medical error reduction and patient safety improvement. Hospitals, as vital organizations in the health care system, can transform to HROs to achieve optimal performance and maximum safety in order to manage unpredicted events efficiently. Therefore, the aim of this research was to determine the knowledge of managers and staffs of Farabi Eye Hospital, Tehran, Iran about HROs model, and the extent of HROs establishment in this hospital in 2015-2016...
January 2018: Iranian Journal of Public Health
Jesse D Schold, Kenneth A Andreoni, Anil K Chandraker, Robert S Gaston, Jayme E Locke, Amit K Mathur, Timothy Pruett, Abbas Rana, Lloyd E Ratner, Laura D Buccini
Outcomes of patients receiving solid organ transplants in the United States are systematically aggregated into bi-annual Program-Specific Reports (PSRs) detailing risk-adjusted survival by transplant center. Recently, the Scientific Registry of Transplant Recipients(SRTR) issued 5-tier ratings evaluating centers based on risk-adjusted one-year graft survival. Our primary aim was to examine the reliability of 5-tier ratings over time. Using ten consecutive PSRs for adult kidney transplant centers from June,2012 to December,2016(n=208) we applied 5-tier ratings to center outcomes and evaluated ratings over time...
January 9, 2018: American Journal of Transplantation
Yeongjun Lee, Jin Young Oh, Taeho Roy Kim, Xiaodan Gu, Yeongin Kim, Ging-Ji Nathan Wang, Hung-Chin Wu, Raphael Pfattner, John W F To, Toru Katsumata, Donghee Son, Jiheong Kang, James R Matthews, Weijun Niu, Mingqian He, Robert Sinclair, Yi Cui, Jeffery B-H Tok, Tae-Woo Lee, Zhenan Bao
Deformable electronic devices that are impervious to mechanical influence when mounted on surfaces of dynamically changing soft matters have great potential for next-generation implantable bioelectronic devices. Here, deformable field-effect transistors (FETs) composed of single organic nanowires (NWs) as the semiconductor are presented. The NWs are composed of fused thiophene diketopyrrolopyrrole based polymer semiconductor and high-molecular-weight polyethylene oxide as both the molecular binder and deformability enhancer...
January 8, 2018: Advanced Materials
M Enciso, J P Carrascosa, J Sarasa, P A Martínez-Ortiz, S Munné, J A Horcajadas, J Aizpurua
STUDY QUESTION: Is it possible to determine the receptivity status of an endometrium by combined quantitative reverse transcription PCR (RT-qPCR) expression analysis of genes involved in endometrial proliferation and immunity? SUMMARY ANSWER: The new ER Map®/ER Grade® test can predict endometrial receptivity status by RT-qPCR using a new panel of genes involved in endometrial proliferation and the maternal immune response associated to embryonic implantation. WHAT IS KNOWN ALREADY: The human endometrium reaches a receptive status adequate for embryonic implantation around Days 19-21 of the menstrual cycle...
January 5, 2018: Human Reproduction
Todd Jaeblon, Kevin J Perry, Joseph A Kufera
OBJECTIVES: To determine if a novel surrogate of waist hip ratio (WHR) is more predictive of wound complications following pelvis or acetabulum stabilization than BMI, and describe the method of measuring a WHR proxy (WHRp). DESIGN: Retrospective review. SETTING: One Level-1 Trauma Center PATIENTS:: 161 patients following operative repair of pelvis and acetabulum fractures. INTERVENTION: Operative stabilization of a pelvic ring injury or acetabular fracture MAIN OUTCOME MEASUREMENTS:: Infection (pin, superficial, deep), Wound healing complication METHODS:: We retrospectively reviewed 161 subjects following operative repair of pelvic and acetabular fractures...
January 8, 2018: Journal of Orthopaedic Trauma
Rafael Gonçalves-Araujo, Benjamin Rabe, Ilka Peeken, Astrid Bracher
As consequences of global warming sea-ice shrinking, permafrost thawing and changes in fresh water and terrestrial material export have already been reported in the Arctic environment. These processes impact light penetration and primary production. To reach a better understanding of the current status and to provide accurate forecasts Arctic biogeochemical and physical parameters need to be extensively monitored. In this sense, bio-optical properties are useful to be measured due to the applicability of optical instrumentation to autonomous platforms, including satellites...
2018: PloS One
Paul B Davenport, Kimberly F Carter, Jeffrey M Echternach, Christopher R Tuck
High-reliability organizations (HROs) demonstrate unique and consistent characteristics, including operational sensitivity and control, situational awareness, hyperacute use of technology and data, and actionable process transformation. System complexity and reliance on information-based processes challenge healthcare organizations to replicate HRO processes. This article describes a healthcare organization's 3-year journey to achieve key HRO features to deliver high-quality, patient-centric care via an operations center powered by the principles of high-reliability data and software to impact patient throughput and flow...
January 5, 2018: Journal of Nursing Administration
Abbas Ostovan, Mehrorang Ghaedi, Maryam Arabi, Qian Yang, Jinhua Li, Lingxin Chen
A novel green synthesis strategy was proposed for preparation of multi-template molecularly imprinted biopolymers (mt-MIBP) in aqueous media with less consumption of organic solvents, which were subsequently used as sorbents of ultrasound-assisted dispersive solid-phase extraction (d-SPE) for simultaneous recognition and efficient separation of B-family vitamins in juice samples followed by high performance liquid chromatography (HPLC) determination. The obtained mt-MIBP was fully characterized by SEM, FT-IR, TEM and BET...
January 4, 2018: ACS Applied Materials & Interfaces
Kamatchi Jothiramalingam Sankaran, Mateusz Ficek, Srinivasu Kunuku, Kalpataru Panda, Chien-Jui Yeh, Jeong Young Park, Miroslaw Sawczak, Paweł Piotr Michałowski, Keh-Chyang Leou, Robert Bogdanowicz, I-Nan Lin, Ken Haenen
Carbon nanomaterials such as nanotubes, nanoflakes/nanowalls, and graphene have been used as electron sources due to their superior field electron emission (FEE) characteristics. However, these materials show poor stability and short lifetimes, which prevent their use in practical device applications. The aim of this study was to find an innovative nanomaterial possessing both high robustness and reliable FEE behavior. Herein, a hybrid structure of self-organized multi-layered graphene (MLG)-boron doped diamond (BDD) nanowall materials with superior FEE characteristics was successfully synthesized using a microwave plasma enhanced chemical vapor deposition process...
January 3, 2018: Nanoscale
László Abrankó, Gary Williamson, Samantha Gardner, Asimina Kerimi
Fatty acyl-Coenzyme A species (acyl-CoAs) are key biomarkers in studies focusing on cellular energy metabolism. Existing analytical approaches are unable to simultaneously detect the full range of short-, medium-, and long-chain acyl-CoAs, while chromatographic limitations encountered in the analysis of limited amounts of biological samples are an often overlooked problem. We report the systematic development of a UHPLC-ESI-MS/MS method which incorporates reversed phase (RP) and hydrophilic interaction liquid chromatography (HILIC) separations in series, in an automated mode...
December 23, 2017: Journal of Chromatography. A
Sung Jin Kim, Jinwoo Byun, Taewoo Jeon, Hyeong Min Jin, Hye Rim Hong, Sang Ouk Kim
Owing to unique potential for high color purity luminance based on low cost solution process, organic/inorganic hybrid perovskite light emitting diodes (PeLEDs) are attracting a great deal of research attention. For high performance PeLEDs, optimum control of perovskite film morphology is a critical parameter. Here we introduce reliable and well-controllable PeLED crystallization process based on beam-damage-free, near-infrared (NIR) laser (λ = 808 nm) irradiation. Morphology of the CH3NH3PbBr3 (MAPbBr3) films can be precisely controlled by laser irradiation condition parameters; power density and beam scan speed...
December 29, 2017: ACS Applied Materials & Interfaces
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