keyword
MENU ▼
Read by QxMD icon Read
search

high reliability organization

keyword
https://www.readbyqxmd.com/read/28929881/high-reliability-in-healthcare-creating-the-culture-and-mindset-for-patient-safety
#1
Bonnie S Cochrane, Mitch Hagins, Gino Picciano, John A King, David A Marshall, Brian Nelson, Craig Deao
Occurrences of patient harm in healthcare represent a significant burden, with serious implications for patients and families and for the capacity of health systems to manage patient access, flow, and wait times. Interest in the science of high reliability, developed originally in industries such as commercial airlines that have demonstrated exceptional safety records, is an emerging trend in healthcare with the potential to help organizations and systems achieve the ultimate goal of zero patient harm. This article argues that zero patient harm is a fundamental imperative, and that high-reliability science can help to accelerate and sustain progress toward this vital goal...
March 2017: Healthcare Management Forum
https://www.readbyqxmd.com/read/28925975/new-insights-into-the-genome-organization-of-yeast-killer-viruses-based-on-atypical-killer-strains-characterized-by-high-throughput-sequencing
#2
Manuel Ramírez, Rocío Velázquez, Antonio López-Piñeiro, Belén Naranjo, Francisco Roig, Carlos Llorens
Viral M-dsRNAs encoding yeast killer toxins share similar genomic organization, but no overall sequence identity. The dsRNA full-length sequences of several known M-viruses either have yet to be completed, or they were shorter than estimated by agarose gel electrophoresis. High-throughput sequencing was used to analyze some M-dsRNAs previously sequenced by traditional techniques, and new dsRNAs from atypical killer strains of Saccharomyces cerevisiae and Torulaspora delbrueckii. All dsRNAs expected to be present in a given yeast strain were reliably detected and sequenced, and the previously-known sequences were confirmed...
September 19, 2017: Toxins
https://www.readbyqxmd.com/read/28924476/clinical-validation-of-real-time-tissue-change-monitoring-during-prostate-tissue-ablation-with-high-intensity-focused-ultrasound
#3
Narendra T Sanghvi, Wo-Hsing Chen, Roy Carlson, Clint Weis, Ralf Seip, Toyoaki Uchida, Michael Marberger
BACKGROUND: The purpose of these clinical studies was to validate a Tissue Change Monitoring (TCM) algorithm in vivo. TCM is a quantitative tool for the real-time assessment of HIFU dose. TCM provides quantitative analysis of the backscatter pulse echo signals (pre and immediately post HIFU) for each individual ablative site, using ultrasonic tissue characterization as a surrogate for monitoring tissue temperature. Real-time analysis generates an energy difference parameter (ΔE in dB) that is proportional to tissue temperature...
2017: Journal of Therapeutic Ultrasound
https://www.readbyqxmd.com/read/28923305/risk-factors-for-mortality-in-patients-with-low-lactate-level-and-septic-shock
#4
Dong Hyun Oh, Moo Hyun Kim, Woo Yong Jeong, Yong Chan Kim, Eun Jin Kim, Je Eun Song, In Young Jung, Su Jin Jeong, Nam Su Ku, Jun Yong Choi, Young Goo Song, June Myung Kim
BACKGROUND: According to the new definition of septic shock, vasopressor therapy and hyperlactatemia are essential for diagnosis. However, there is controversy regarding the cutoff value for lactate, and prognostic factors in patients with septic shock and hypolactatemia. This study evaluated the prognostic significance of the cutoff value for lactate level in septic shock patients. METHODS: The retrospective observational cohort study enrolled 1043 patients aged ≥18 years who meet the revised definition of septic shock...
August 26, 2017: Journal of Microbiology, Immunology, and Infection, Wei Mian Yu Gan Ran za Zhi
https://www.readbyqxmd.com/read/28921989/universal-calibration-of-computationally-predicted-n-1s-binding-energies-for-interpretation-of-xps-experimental-measurements
#5
Jing Zhao, Fei Gao, Sidharam Pundlik Pujari, Han Zuilhof, Andrew Teplyakov
Computationally predicted N 1s core level energies are commonly used to interpret the experimental measurements obtained with X-ray photoelectron spectroscopy. This work compares the application of Koopmans' theorem to core electrons using the B3LYP functional with two commonly used basis sets, analyses the factors relevant to the comparison of the computational with experimental data, and presents several correlations that allow an accurate prediction of the N 1s binding energy. The first correlation is obtained with a series of known nitrogen-containing functional groups on well-characterized organic monolayers...
September 18, 2017: Langmuir: the ACS Journal of Surfaces and Colloids
https://www.readbyqxmd.com/read/28918260/organization-of-sensory-feature-selectivity-in-the-whisker-system
#6
Michael R Bale, Miguel Maravall
Our sensory receptors are faced with an onslaught of different environmental inputs. Each sensory event or encounter with an object involves a distinct combination of physical energy sources impinging upon receptors. In the rodent whisker system, each primary afferent neuron located in the trigeminal ganglion innervates and responds to a single whisker and encodes a distinct set of physical stimulus properties - features - corresponding to changes in whisker angle and shape and the consequent forces acting on the whisker follicle...
September 13, 2017: Neuroscience
https://www.readbyqxmd.com/read/28916761/chronic-interfacing-with-the-autonomic-nervous-system-using-carbon-nanotube-cnt-yarn-electrodes
#7
Grant A McCallum, Xiaohong Sui, Chen Qiu, Joseph Marmerstein, Yang Zheng, Thomas E Eggers, Chuangang Hu, Liming Dai, Dominique M Durand
The ability to reliably and safely communicate chronically with small diameter (100-300 µm) autonomic nerves could have a significant impact in fundamental biomedical research and clinical applications. However, this ability has remained elusive with existing neural interface technologies. Here we show a new chronic nerve interface using highly flexible materials with axon-like dimensions. The interface was implemented with carbon nanotube (CNT) yarn electrodes to chronically record neural activity from two separate autonomic nerves: the glossopharyngeal and vagus nerves...
September 15, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28916040/matrix-assisted-laser-desorption-ionization-mass-spectrometry-for-the-analysis-of-polyamines-in-plant-micro-tissues-using-cucurbituril-as-a-host-molecule
#8
Jun Ding, Simin Liu, Hua-Ming Xiao, Tian-Tian Ye, Ping Zhou, Yu-Qi Feng
In this study, a matrix-assisted laser desorption/ionization (MALDI) mass spectrometry (MS) strategy using cucurbit[n]uril (CB[n]) as a host molecule is proposed for the analysis of low molecular weight (LMW) compounds in complex samples. As a proof-of-concept, CB[6] was selected as the host molecule, and endogenous polyamines in plant tissue were chosen as the target analytes. Due to the molecular recognition and mass shifting properties of CB[6], the ionic signals associated with polyamines were moved to the higher mass region (>1000 Da) after specifically binding to CB[6], while signal interference derived from the conventional organic matrix and the complex sample matrix remained in the low mass region because of the incompatibility of their molecular size with CB[6] cavities...
September 22, 2017: Analytica Chimica Acta
https://www.readbyqxmd.com/read/28912698/altered-rich-club-and-frequency-dependent-subnetwork-organization-in-mild-traumatic-brain-injury-a-meg-resting-state-study
#9
Marios Antonakakis, Stavros I Dimitriadis, Michalis Zervakis, Andrew C Papanicolaou, George Zouridakis
Functional brain connectivity networks exhibit "small-world" characteristics and some of these networks follow a "rich-club" organization, whereby a few nodes of high connectivity (hubs) tend to connect more densely among themselves than to nodes of lower connectivity. The Current study followed an "attack strategy" to compare the rich-club and small-world network organization models using Magnetoencephalographic (MEG) recordings from mild traumatic brain injury (mTBI) patients and neurologically healthy controls to identify the topology that describes the underlying intrinsic brain network organization...
2017: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/28912162/regional-cellular-environment-shapes-phenotypic-variations-of-hippocampal-and-neocortical-chandelier-cells
#10
Yugo Ishino, Michael J Yetman, Serena M Sossi, André Steinecke, Yasufumi Hayano, Hiroki Taniguchi
Different cortical regions processing distinct information, such as the hippocampus and the neocortex, share common cellular components and circuit motifs but form unique networks by modifying these cardinal units. Cortical circuits include diverse types of GABAergic interneurons (INs) that shape activity of excitatory principal neurons (PNs). Canonical IN types conserved across distinct cortical regions have been defined by their morphological, electrophysiological, and neurochemical properties. However, it remains largely unknown whether canonical IN types undergo specific modifications in distinct cortical regions and display "regional variants"...
September 14, 2017: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/28912116/reliability-of-an-e-pro-tool-of-eortc-qlq-c30-for-measurement-of-health-related-quality-of-life-in-patients-with-breast-cancer-prospective-randomized-trial
#11
Markus Wallwiener, Lina Matthies, Elisabeth Simoes, Lucia Keilmann, Andreas D Hartkopf, Alexander N Sokolov, Christina B Walter, Nina Sickenberger, Stephanie Wallwiener, Manuel Feisst, Paul Gass, Peter A Fasching, Michael P Lux, Diethelm Wallwiener, Florin-Andrei Taran, Joachim Rom, Andreas Schneeweiss, Joachim Graf, Sara Y Brucker
BACKGROUND: Breast cancer represents the most common malignant disease in women worldwide. As currently systematic palliative treatment only has a limited effect on survival rates, the concept of health-related quality of life (HRQoL) is gaining more and more importance in the therapy setting of metastatic breast cancer. One of the major patient-reported outcomes (PROs) for measuring HRQoL in patients with breast cancer is provided by the European Organization for Research and Treatment of Cancer (EORTC)...
September 14, 2017: Journal of Medical Internet Research
https://www.readbyqxmd.com/read/28910821/vascular-disrupting-agent-in-pancreatic-and-hepatic-tumour-allografts-observations-of-location-dependent-efficacy-by-mri-microangiography-and-histomorphology
#12
Ting Yin, Yewei Liu, Ronald Peeters, Yuanbo Feng, Jie Yu, Uwe Himmelreich, Raymond Oyen, Yicheng Ni
BACKGROUND: Tumours growing in organs of different vascular environment could exhibit diverse responses to vascular disrupting agent (VDA). This study was aimed to identify in vivo imaging biomarkers for evaluation of pancreatic and hepatic tumours and comparison of their responses to a VDA Combretastatin A4 Phosphate (CA4P) using multiparametric MRI. METHODS: Male WAG/Rij rats were used for orthotopic pancreatic head tumour and hepatic tumour implantation; tumour growth was monitored by 3D isotropic MRI using a 3...
September 14, 2017: British Journal of Cancer
https://www.readbyqxmd.com/read/28906012/pacbio-metabarcoding-of-fungi-and-other-eukaryotes-errors-biases-and-perspectives
#13
Leho Tedersoo, Ave Tooming-Klunderud, Sten Anslan
Second-generation, high-throughput sequencing methods have greatly improved our understanding of the ecology of soil microorganisms, yet the short barcodes (< 500 bp) provide limited taxonomic and phylogenetic information for species discrimination and taxonomic assignment. Here, we utilized the third-generation Pacific Biosciences (PacBio) RSII and Sequel instruments to evaluate the suitability of full-length internal transcribed spacer (ITS) barcodes and longer rRNA gene amplicons for metabarcoding Fungi, Oomycetes and other eukaryotes in soil samples...
September 14, 2017: New Phytologist
https://www.readbyqxmd.com/read/28902908/histological-assessment-of-granulomas-in-natural-and-experimental-schistosoma-mansoni-infections-using-whole-slide-imaging
#14
Kátia B Amaral, Thiago P Silva, Felipe F Dias, Kássia K Malta, Florence M Rosa, Sócrates F Costa-Neto, Rosana Gentile, Rossana C N Melo
The pathology of schistosomiasis mansoni, a neglected tropical disease of great clinical and socioeconomic importance, results from the parasite eggs that become trapped in host tissues, particularly in the liver and intestines. Continuous antigenic stimulation from these eggs leads to recruitment of inflammatory cells to the sites of infection with formation of periovular granulomas. These complex structures have variable size and composition and are the most striking histopathological feature of schistosomiasis mansoni...
2017: PloS One
https://www.readbyqxmd.com/read/28902270/public-health-response-and-lessons-learned-from-the-2014-chikungunya-epidemic-in-grenada
#15
Martin S Forde, Francis Martin, George Mitchell, Satesh Bidaisee
In June 2014, the first cases of chikungunya virus (CHIKV) were diagnosed on the island of Carriacou, part of the tri-island state of Grenada. In the three months that followed, CHIKV spread rapidly, with conservative estimates of the population infected of at least 60%. Multiple challenges were encountered in the battle to manage the spread and impact of this high-attack rate virus, including 1) limited indigenous laboratory diagnostic capabilities; 2) an under-resourced health care system; 3) a skeptical general public, hesitant to accept facts about the origin and mode of transmission of the new virus; and 4) resistance to the vector control strategies used...
August 21, 2017: Revista Panamericana de Salud Pública, Pan American Journal of Public Health
https://www.readbyqxmd.com/read/28901955/hepg2-and-human-healthy-hepatocyte-in-vitro-culture-and-co-culture-in-pcl-electrospun-platforms
#16
Ines Fasolino, Vincenzo Guarino, Marica Marrese, Valentina Cirillo, Marianna Vallifuoco, Maria Luisa Tamma, Valentina Vassallo, Adele Bracco, Fulvio Calise, Luigi Ambrosio
The discovery of new drugs to treat pathological cells in the case of aggressive liver primary cancer is imposing the identification of high-throughput screening systems to predict the in vivo response of new therapeutic molecules, in order to reduce current use of animals and drug testing costs. Recently, micro/nanostructured scaffolds have been adopted to reproduce the hepatic microenvironment due to their higher similarity to the biological niche with respect to the traditional two-dimensional culture plate, so providing novel in vitro models for reliably understanding molecular mechanisms related to cancer cells activity...
September 13, 2017: Biomedical Materials
https://www.readbyqxmd.com/read/28901738/determination-of-the-13c-12c-carbon-isotope-ratio-in-carbonates-and-bicarbonates-by-13c-nmr-spectroscopy
#17
Concetta Pironti, Raffaele Cucciniello, Federica Camin, Agostino Tonon, Oriana Motta, Antonio Proto
This paper is the first study focused on the innovative application of 13C NMR (Nuclear Magnetic Resonance) spectroscopy to determine the bulk 13C/12C carbon isotope ratio, at natural abundance, in inorganic carbonates and bicarbonates. In the past, 13C NMR spectroscopy (irm-13C NMR) was mainly used to measure isotope ratio monitoring with the potential of conducting 13C position-specific isotope analysis of organic molecules with high precision. The reliability of the newly developed methodology for the determination of stable carbon isotope ratio was evaluated in comparison with the method chosen in the past for these measurements, i...
September 13, 2017: Analytical Chemistry
https://www.readbyqxmd.com/read/28895921/food-and-beverage-marketing-in-schools-a-review-of-the-evidence
#18
REVIEW
Cayley E Velazquez, Jennifer L Black, Monique Potvin Kent
Despite growing interest from government agencies, non-governmental organizations and school boards in restricting or regulating unhealthy food and beverage marketing to children, limited research has examined the emerging knowledge base regarding school-based food and beverage marketing in high-income countries. This review examined current approaches for measuring school food and beverage marketing practices, and evidence regarding the extent of exposure and hypothesized associations with children's diet-related outcomes...
September 12, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28895491/preliminary-validation-of-the-whodas-2-0-for-mild-traumatic-brain-injury
#19
Deborah Snell, Grant L Iverson, William Panenka, Noah D Silverberg
The purpose of this study is to examine the reliability, factor structure, and validity of the World Health Organization Disability Assessment Schedule (WHODAS 2.0 12-item version) in a sample of patients who were slow to recover from a mild traumatic brain injury (MTBI). Participants were 79 adults with MTBI recruited from one of four specialty outpatient clinics in Vancouver, Canada. The WHODAS 2.0 12-item version is a disease-non-specific measure of disability representing six International Classification of Disability, Functioning, and Health activity and participation domains including cognition, mobility, self-care, interpersonal functioning, life activities, and participation...
September 12, 2017: Journal of Neurotrauma
https://www.readbyqxmd.com/read/28894412/recording-spikes-activity-in-cultured-hippocampal-neurons-using-flexible-or-transparent-graphene-transistors
#20
Farida Veliev, Zheng Han, Dipankar Kalita, Anne Briançon-Marjollet, Vincent Bouchiat, Cécile Delacour
The emergence of nanoelectronics applied to neural interfaces has started few decades ago, and aims to provide new tools for replacing or restoring disabled functions of the nervous systems as well as further understanding the evolution of such complex organization. As the same time, graphene and other 2D materials have offered new possibilities for integrating micro and nano-devices on flexible, transparent, and biocompatible substrates, promising for bio and neuro-electronics. In addition to many bio-suitable features of graphene interface, such as, chemical inertness and anti-corrosive properties, its optical transparency enables multimodal approach of neuronal based systems, the electrical layer being compatible with additional microfluidics and optical manipulation ports...
2017: Frontiers in Neuroscience
keyword
keyword
53428
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"