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Alcohol review

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https://www.readbyqxmd.com/read/29474454/the-impact-of-poverty-reduction-and-development-interventions-on-non-communicable-diseases-and-their-behavioural-risk-factors-in-low-and-lower-middle-income-countries-a-systematic-review
#1
Jessie Pullar, Luke Allen, Nick Townsend, Julianne Williams, Charlie Foster, Nia Roberts, Mike Rayner, Bente Mikkelsen, Francesco Branca, Kremlin Wickramasinghe
INTRODUCTION: Non-communicable diseases (NCDs) disproportionately affect low- and lower-middle income countries (LLMICs) where 80% of global NCD related deaths occur. LLMICs are the primary focus of interventions to address development and poverty indicators. We aimed to synthesise the evidence of these interventions' impact on the four primary NCDs (cardiovascular disease, diabetes, chronic respiratory disease and cancer) and their common behavioural risk factors (unhealthy diets, physical inactivity, tobacco and alcohol use)...
2018: PloS One
https://www.readbyqxmd.com/read/29474271/de-escalation-treatment-of-human-papillomavirus-positive-oropharyngeal-squamous-cell-carcinoma-an-evidence-based-review-for-the-locally-advanced-disease
#2
Gustavo T Stock, Renata R C Colombo Bonadio, Gilberto de Castro
PURPOSE OF REVIEW: Oropharyngeal cancer (OPC) incidence is increasing worldwide, especially in developed countries where it seems to be etiologically related to the elevating rates of high-risk human papillomavirus (HPV) infection. Considered a distinct disease because of its weak correlation with the traditional risk factors (tobacco use and alcohol), it has different patterns of survival outcomes, locoregional and distant failure, generally with better prognosis independently of the treatment...
February 22, 2018: Current Opinion in Oncology
https://www.readbyqxmd.com/read/29473535/an-overview-on-hepatoprotective-effects-of-thymoquinone
#3
Tahereh Farkhondeh, Mohammad-Foad Noorbakhsh, Farzad Hayati, Saeed Samarghandian, Hanieh Shaterzadeh-Yazdi
Liver as an essential organ has an important function in metabolism and waste secretion from the body. Disorders of this organ may caused by several reasons such as high alcoholic consumption, various chemical or microbial agents and various hepatic cancers. Reactive and oxidative stress and oxygen species (ROS) are introduced the main mechanisms of these hepatic injuries. The seeds of Nigella sativa (Family Ranunculaceae) which is known as black seed, is widely used as a medicinal herb for cure or prevention of many of diseases such as liver problems...
February 20, 2018: Recent Patents on Food, Nutrition & Agriculture
https://www.readbyqxmd.com/read/29473267/recent-advances-in-the-synthesis-of-%C3%AE-functionalized-ketones-via-radical-mediated-1-2-rearrangement-of-allylic-alcohols
#4
Wei-Zhi Weng, Bo Zhang
β-Functionalized ketones are a highly important and valuable class of compounds, which have gained increasing attention from organic chemists due to their intensive uses as versatile synthetic intermediates and building blocks in complex molecule assembly and natural product synthesis. Accordingly, there is continuing interest in the development of new approaches for the synthesis of β-functionalized ketones. In recent years, radical-mediated 1,2-rearrangement reactions of allylic alcohols, which proceed through cationic (semipinacol) rearrangements or radical (neophyl) rearrangements, have presented an attractive and powerful strategy to access various diversely β-functionalized ketones...
February 22, 2018: Chemistry: a European Journal
https://www.readbyqxmd.com/read/29472712/direct-effects-of-thyroid-hormones-on-hepatic-lipid-metabolism
#5
REVIEW
Rohit A Sinha, Brijesh K Singh, Paul M Yen
It has been known for a long time that thyroid hormones have prominent effects on hepatic fatty acid and cholesterol synthesis and metabolism. Indeed, hypothyroidism has been associated with increased serum levels of triglycerides and cholesterol as well as non-alcoholic fatty liver disease (NAFLD). Advances in areas such as cell imaging, autophagy and metabolomics have generated a more detailed and comprehensive picture of thyroid-hormone-mediated regulation of hepatic lipid metabolism at the molecular level...
February 23, 2018: Nature Reviews. Endocrinology
https://www.readbyqxmd.com/read/29472174/peer-based-social-media-features-in-behavior-change-interventions-systematic-review
#6
REVIEW
Sheik Mohammad Roushdat Ally Elaheebocus, Mark Weal, Leanne Morrison, Lucy Yardley
BACKGROUND: Incorporating social media features into digital behavior change interventions (DBCIs) has the potential to contribute positively to their success. However, the lack of clear design principles to describe and guide the use of these features in behavioral interventions limits cross-study comparisons of their uses and effects. OBJECTIVE: The aim of this study was to provide a systematic review of DBCIs targeting modifiable behavioral risk factors that have included social media features as part of their intervention infrastructure...
February 22, 2018: Journal of Medical Internet Research
https://www.readbyqxmd.com/read/29471983/current-trends-in-methylotrophy
#7
REVIEW
Ludmila Chistoserdova, Marina G Kalyuzhnaya
Methylotrophy is a field of study dealing with microorganisms capable of utilization of compounds devoid of carbon-carbon bonds (C1 compounds). In this review, we highlight several emerging trends in methylotrophy. First, we discuss the significance of the recent discovery of lanthanide-dependent alcohol dehydrogenases for understanding both the occurrence and the distribution of methylotrophy functions among bacteria, and then we discuss the newly appreciated role of lanthanides in biology. Next, we describe the detection of other methylotrophy pathways across novel bacterial taxa and insights into the evolution of methylotrophy...
February 19, 2018: Trends in Microbiology
https://www.readbyqxmd.com/read/29470605/considering-the-context-social-factors-in-responses-to-drugs-in-humans
#8
REVIEW
Harriet de Wit, Michael Sayette
BACKGROUND: Drugs are typically used in social settings. Here, we consider two factors that may contribute to this observation: (i) the presence of other people may enhance the positive mood effects of a drug, and conversely, (ii) drugs may enhance the value of social stimuli. METHODS: We review evidence from controlled laboratory studies with human volunteers, which investigated either of these interactions between social factors and responses to drugs. We examine the bidirectional effects of social stimuli and single doses of alcohol, stimulants, opioids, and cannabis...
February 22, 2018: Psychopharmacology
https://www.readbyqxmd.com/read/29467662/purinergic-signaling-in-neuron-astrocyte-interactions-circadian-rhythms-and-alcohol-use-disorder
#9
REVIEW
Daniel Lindberg, Lindsey Andres-Beck, Yun-Fang Jia, Seungwoo Kang, Doo-Sup Choi
Alcohol use disorder (AUD) is a debilitating condition marked by cyclic patterns of craving, use, and withdrawal. These pathological behaviors are mediated by multiple neurotransmitter systems utilizing glutamate, GABA, dopamine, ATP, and adenosine. In particular, purines such as ATP and adenosine have been demonstrated to alter the phase and function of the circadian clock and are reciprocally regulated by the clock itself. Importantly, chronic ethanol intake has been demonstrated to disrupt the molecular circadian clock and is associated with altered circadian patterns of activity and sleep...
2018: Frontiers in Physiology
https://www.readbyqxmd.com/read/29467469/effects-of-adolescent-alcohol-consumption-on-the-brain-and-behaviour
#10
REVIEW
Linda P Spear
Per occasion, alcohol consumption is higher in adolescents than in adults in both humans and laboratory animals, with changes in the adolescent brain probably contributing to this elevated drinking. This Review examines the contributors to and consequences of the use of alcohol in adolescents. Human adolescents with a history of alcohol use differ neurally and cognitively from other adolescents; some of these differences predate the commencement of alcohol consumption and serve as potential risk factors for later alcohol use, whereas others emerge from its use...
February 15, 2018: Nature Reviews. Neuroscience
https://www.readbyqxmd.com/read/29466868/finding-the-optimal-treatment-model-a-systematic-review-of-treatment-for-co-occurring-alcohol-misuse-and-depression
#11
Breanne Hobden, Jamie Bryant, Mariko Carey, Amanda L Baker, Michael Farrell, Christopher Oldmeadow, Richard P Mattick, Anthony Shakeshaft, Rob Sanson-Fisher
OBJECTIVES: Alcohol misuse and depression are commonly co-occurring conditions. To date, no review has examined the most efficacious treatment model for psychosocial treatment of co-occurring alcohol misuse and depression. This systematic review determined the: (i) methodological quality of publications examining psychosocial treatment of co-occurring alcohol misuse and depression using a sequential, parallel or integrated treatment model; and (ii) effectiveness of each dual treatment model compared to single treatment for those with co-occurring alcohol misuse and depression...
February 1, 2018: Australian and New Zealand Journal of Psychiatry
https://www.readbyqxmd.com/read/29466805/personality-disorder-and-alcohol-use-disorder-an-overview
#12
Giles Newton-Howes, James Foulds
BACKGROUND: Clinically, personality disorder (PD) commonly coexists with alcohol use disorder (AUD), although within mainstream mental health services both of these mental disorders are routinely overlooked. Despite a rich literature examining the interactions between AUD and personality functioning, personality traits, and PD, there remains conflicting evidence as to the degree of association and impact of one on the other. METHODS: A narrative review and a synthesis of the literature were done...
February 21, 2018: Psychopathology
https://www.readbyqxmd.com/read/29464852/perceptions-of-driving-after-marijuana-use-compared-to-alcohol-use-among-rural-american-young-adults
#13
Kaylin M Greene
INTRODUCTION AND AIMS: Substance use contributes to motor vehicle crashes, the leading cause of death among young adults. The current qualitative study examined perceptions of the acceptability and harms associated with driving after marijuana versus alcohol use in rural America. Illuminating rural perspectives is critical given that the motor vehicle fatality rate is twice as high in rural as in urban areas in the USA. DESIGN AND METHODS: In 2015-2016, 72 young adults aged 18-25 years (Mage = 20...
February 21, 2018: Drug and Alcohol Review
https://www.readbyqxmd.com/read/29464442/the-use-of-vv-ecmo-in-patients-with-drug-dependencies
#14
George Stoyle, Peter Fawcett, Ignacio Malagon
The purpose of this study is to determine the effect of illicit drug and alcohol dependencies on mortality, length of stay, and complications in patients who have been supported with veno-venous extracorporeal membrane oxygenation (VV-ECMO) following respiratory failure not responsive to conventional methods of ventilation. 584 VV-ECMO referrals received at Wythenshawe Hospital were reviewed for evidence of drug dependency. 13 patients were identified as being drug-dependent and having undergone treatment with VV-ECMO...
February 20, 2018: Journal of Artificial Organs: the Official Journal of the Japanese Society for Artificial Organs
https://www.readbyqxmd.com/read/29463026/the-nile-rat-arvicanthis-niloticus-as-a-superior-carbohydrate-sensitive-model-for-type-2-diabetes-mellitus-t2dm
#15
REVIEW
Avinaash Subramaniam, Michelle Landstrom, Alice Luu, K C Hayes
Type II diabetes mellitus (T2DM) is a multifactorial disease involving complex genetic and environmental interactions. No single animal model has so far mirrored all the characteristics or complications of diabetes in humans. Since this disease represents a chronic nutritional insult based on a diet bearing a high glycemic load, the ideal model should recapitulate the underlying dietary issues. Most rodent models have three shortcomings: (1) they are genetically or chemically modified to produce diabetes; (2) unlike humans, most require high-fat feeding; (3) and they take too long to develop diabetes...
February 18, 2018: Nutrients
https://www.readbyqxmd.com/read/29462346/a-systematic-review-of-economic-evaluations-of-local-authority-commissioned-preventative-public-health-interventions-in-overweight-and-obesity-physical-inactivity-alcohol-and-illicit-drugs-use-and-smoking-cessation-in-the-united-kingdom
#16
Pam White, Helen Skirrow, Abraham George, Anjum Memon
Background: Since 2013, local authorities in England have been responsible for commissioning preventative public health interventions. The aim of this systematic review was to support commissioning by collating published data on economic evaluations and modelling of local authority commissioned public health preventative interventions in the UK. Methods: Following the PRISMA protocol, we searched for economic evaluations of preventative intervention studies in four different areas: overweight and obesity, physical inactivity, alcohol and illicit drugs use and smoking cessation...
February 16, 2018: Journal of Public Health
https://www.readbyqxmd.com/read/29460838/-phospholipase-d-its-role-in-metabolism-processes-and-disease-development
#17
REVIEW
G V Ramenskaia, E V Melnik, A E Petukhov
Phospholipase D (PLD) is one of the key enzymes that catalyzes the hydrolysis of cell membrane phospholipids. In this review current knowledge about six human PLD isoforms, their structure and role in physiological and pathological processes is summarized. Comparative analysis of PLD isoforms structure is presented. The mechanism of the hydrolysis and transphosphatidylation performed by PLD is described. The PLD1 and PLD2 role in the pathogenesis of some cancer, infectious, thrombotic and neurodegenerative diseases is analyzed...
January 2018: Biomedit︠s︡inskai︠a︡ Khimii︠a︡
https://www.readbyqxmd.com/read/29460818/sarcopenic-obesity-and-health-outcomes-in-patients-seeking-weight-loss-treatment
#18
Jingjie Xiao, Angelina Cain, Sarah A Purcell, Michael J Ormsbee, Robert J Contreras, Jeong-Su Kim, Robert Thornberry, Dawn Springs, M Cristina Gonzalez, Carla M Prado
AIM: To investigate the prevalence of sarcopenic obesity (SO) and its association with health outcomes in patients seeking weight loss treatment from a bariatric center. METHODS: In this retrospective study, patients [≥18 years old, body mass index (BMI) ≥30 kg/m2 ] from the Tallahassee Memorial Bariatric Center and with baseline body composition assessment by bioelectrical impedance analysis were included. Fat mass index (FMI = fat mass/height2 ) and fat-free mass index (FFMI = fat free mass/height2 ) were calculated...
February 2018: Clinical Nutrition ESPEN
https://www.readbyqxmd.com/read/29460521/hpv-acting-on-e-cadherin-p53-and-p16-literature-review
#19
L Ottria, V Candotto, F Cura, L Baggi, C Arcuri, M Nardone, R M Gaudio, R Gatto, F Spadari, F Carinci
In addition to tobacco and alcohol consumption, the two main risk factors for oral squamous cell carcinoma (OSCC), recent studies have revealed infections with human papilloma virus (HPV) as an additional risk factor for OSCC development. In the field of head and neck malignancies, the prevalence of HPV infections in oropharyngeal cancer (OC) ranges in different studies up to 84%. While HPV infection is discussed as an independent risk factor in this region, its distinguished role in carcinogenesis of tumours localized to the oral cavity remains uncertain...
January 2018: Journal of Biological Regulators and Homeostatic Agents
https://www.readbyqxmd.com/read/29460163/noradrenergic-targets-for-the-treatment-of-alcohol-use-disorder
#20
REVIEW
Carolina L Haass-Koffler, Robert M Swift, Lorenzo Leggio
The role of norepinephrine (NE) in the development of alcohol use disorder (AUD) has been studied over the past several decades. However, the NE system has been largely ignored for many years as a potential target for medication development for AUD. More recently, preclinical and clinical studies have demonstrated the potential value of targeting NE signaling for developing new pharmacological treatments for AUD. This review contributes to a special issue of Psychopharmacology focused on promising targets for alcohol addiction...
February 20, 2018: Psychopharmacology
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