keyword
https://read.qxmd.com/read/38707955/beyond-immune-balance-the-pivotal-role-of-decidual-regulatory-t-cells-in-unexplained-recurrent-spontaneous-abortion
#1
REVIEW
Qing-Hui Li, Qiu-Yan Zhao, Wei-Jing Yang, Ai-Fang Jiang, Chun-E Ren, Yu-Han Meng
Recurrent spontaneous abortion (RSA) is defined as two or more consecutive pregnancy failures, which brings tremendous stress to women of childbearing age and seriously affects family well-being. However, the reason in about 50% of cases remains unknown and is defined as unexplained recurrent spontaneous abortion (URSA). The immunological perspective in URSA has attracted widespread attention in recent years. The embryo is regarded as a semi-allogeneic graft to the mother. A successful pregnancy requires transition to an immune environment conducive to embryo survival at the maternal-fetal interface...
2024: Journal of Inflammation Research
https://read.qxmd.com/read/38701716/the-relationship-between-religious-affiliation-and-menopause-symptoms-and-attitudes-in-united-states-women
#2
JOURNAL ARTICLE
Annika Agarwal, Holly N Thomas
OBJECTIVES: This study's aim is to examine patterns of menopause symptoms and attitudes among United States women from different religious affiliations. STUDY DESIGN: We used data from a national sample of midlife and older adults. For this analysis, we included only women who were postmenopausal or had undergone hysterectomy. We constructed univariate and multivariate logistic regression models to examine the relationship between religious affiliation and menopause symptoms and attitudes while adjusting for potential confounders...
April 28, 2024: Maturitas
https://read.qxmd.com/read/38700571/exosomal-yb-1-facilitates-ovarian-restoration-by-malat1-mir-211-5p-foxo-3-axis
#3
JOURNAL ARTICLE
Mengxue Zhang, Jie Xing, Shijie Zhao, Minjun Lu, Yueqin Liu, Li Lin, Wujiang Gao, Lu Chen, Wenxin Li, Junyu Shang, Jiamin Zhou, Xinming Yin, Xiaolan Zhu
Premature ovarian failure (POF) affects many adult women less than 40 years of age and leads to infertility. Mesenchymal stem cells-derived small extracellular vesicles (MSCs-sEVs) are attractive candidates for ovarian function restoration and folliculogenesis for POF due to their safety and efficacy, however, the key mediator in MSCs-sEVs that modulates this response and underlying mechanisms remains elusive. Herein, we reported that YB-1 protein was markedly downregulated in vitro and in vivo models of POF induced with H2 O2 and CTX respectively, accompanied by granulosa cells (GCs) senescence phenotype...
May 3, 2024: Cell Biology and Toxicology
https://read.qxmd.com/read/38700256/attitudes-and-behaviors-regarding-sun-exposure-in-japan-compared-to-europe-and-north-america
#4
JOURNAL ARTICLE
A Morita, H W Lim, T Passeron, C L Goh, H Y Kang, F Ly, J Ocampo-Candiani, S Puig, S Schalka, L Wei, A L Demessant, C Le Floc'h, D Kerob, B Dreno, J Krutmann
The objective of our study was to assess the attitudes and behaviors in Japan regarding sun exposure and compare them to those in Europe and North America. The study population was a representative sample of individuals aged >18 years from Ipsos panels in Japan (N = 1000), North America (N = 1000), and Europe (N = 6000) using the quota method. Questionnaires covered habits, practices, and perceptions regarding sun exposure. Results revealed that the majority of people (80...
May 3, 2024: Journal of Dermatology
https://read.qxmd.com/read/38694965/the-effect-of-obesity-on-severity-of-asthma-an-observational-prospective-study-from-pakistan
#5
JOURNAL ARTICLE
Sara Shahid, Saad S Alqahtani, Mishal Bajwa, Mahnoor Rashid, Anosh Sana, Amna Bajwa, Abdul N Ali, Ahmad K Ariffin, Mahgull Mahmood, Fahad Ahmed, Muhammad Abid Mustafa
OBJECTIVE: The current research study aimed to access the relationship between obesity and asthma exacerbations and severity among adult patients at the outpatient section of a federal hospital (PIMS) in Islamabad, Pakistan. METHODS: A cross-sectional research study was carried out on 207 asthma adult patients belonging to different areas and ethnic groups from the country. The study setting was the PIMS hospital, which attracts patients from all over the country due to its facilities and cost-effective treatments...
2024: Journal of Pharmacy & Bioallied Sciences
https://read.qxmd.com/read/38693442/the-standardization-of-a-new-explicit-pornographic-picture-set-epps
#6
JOURNAL ARTICLE
Sabine Prantner, Cristina Giménez-García, Alejandro Espino-Payá, Miguel A Escrig, Elisabeth Ruiz-Padial, Rafael Ballester-Arnal, M Carmen Pastor
Pictures with affective content have been extensively used in scientific studies of emotion and sexuality. However, only a few standardized picture sets have been developed that offer explicit images, with most lacking pornographic pictures depicting diverse sexual practices. This study aimed to fill this gap through developing a standardized affective set of diverse pornographic pictures (masturbation, oral sex, vaginal sex, anal sex, group sex, paraphilia) of same-sex and opposite-sex content, offering dimensional affective ratings of valence, arousal, and dominance, as well as co-elicited discrete emotions (disgust, moral and ethical acceptance)...
May 1, 2024: Behavior Research Methods
https://read.qxmd.com/read/38680046/strategies-to-attract-school-leavers-to-nurse-education-programmes-an-integrative-literature-review
#7
JOURNAL ARTICLE
Emily Clipstone, Leire Ambrosio
The shortfall of nurses in the UK has led to concerns that there are insufficient staff to ensure safe and high-quality care. To address this shortfall, one group to focus on for recruiting nursing students is school-leavers. This article reports on an integrative literature review that was conducted to explore the educational strategies used to attract school-leavers to undergraduate nurse education programmes. The review identified that a variety of educational strategies were used, and all of the included studies reported positive effects on school pupils' intention to undertake nursing studies...
April 29, 2024: Nursing Management (Harrow)
https://read.qxmd.com/read/38679979/patients-satisfaction-after-breast-reconstruction-surgery-using-autologous-versus-implants-a-meta-analysis
#8
COMPARATIVE STUDY
Amru Sungkar, Kristanto Yuli Yarso, Didit Fajar Nugroho, Dian Ibnu Wahid, Chandra Analis Permatasari
INTRODUCTION: Breast cancer is a common disease that affects women globally and causes physical and emotional challenges. Breast reconstructive surgery aims to restore the shape of the breast after a mastectomy. Two common approaches used today are tissue-based or autologous and implant-based reconstruction. Autologous breast reconstruction has the advantage of being more affordable, but the resulting shape is less attractive. At the same time, the implant technique produces a more pleasing shape at a more expensive cost...
April 1, 2024: Asian Pacific Journal of Cancer Prevention: APJCP
https://read.qxmd.com/read/38667619/why-should-diabetic-women-be-active-the-role-of-personality-self-esteem-body-esteem-and-imagery
#9
JOURNAL ARTICLE
Dagmara Budnik-Przybylska, Malwina Fituch, Aleksandra Kowalewska
Diabetes is one of the fastest spreading diseases in the 21st century. The aim of the study is twofold: (1) to find differences in personality traits, self-esteem, body-esteem, and imagery between healthy women and women with diabetes; (2) to verify whether there are differences in the analyzed factors among women with diabetes who engage in sports compared to those who do not. We used 3 questionnaires: Imagination in Sport-short form, Self-Esteem Scale (SES), and BFIS Personality, which were tested online...
April 18, 2024: Healthcare (Basel, Switzerland)
https://read.qxmd.com/read/38663304/trauma-in-pregnancy-a-narrative-review-of-the-current-literature
#10
REVIEW
Michael D April, Brit Long
INTRODUCTION: Trauma accounts for nearly half of all deaths of pregnant women. Pregnant women have distinct physiologic and anatomic characteristics which complicate their management following major trauma. OBJECTIVE: This paper comprises a narrative review of the most recent literature informing the management of pregnant trauma patients. DISCUSSION: The incidence of trauma during pregnancy is 6-8%. The focus of clinical assessment must be on the mother, starting with the primary survey...
April 20, 2024: American Journal of Emergency Medicine
https://read.qxmd.com/read/38662760/a-biological-approach-to-periorbital-aesthetics-in-caucasian-women-a-review-of-the-literature
#11
JOURNAL ARTICLE
Erik Zanchetta-Balint, Barbara Hersant, Lyor Hanan, Jean Paul Meningaud
The face plays an important role in human interactions, and the periorbital region is particularly important to allow recognition and attractiveness. There are several studies on the beauty of the periorbital region using a variety of methodologies, but few articles consider the attractiveness factors derived from evolutionary psychology such as symmetry, dimorphism, age and average, neoteny and facial expression. The aim of this study is to identify periorbital attractiveness criteria in Caucasian women based on experimental studies and to interpret them in the light of studies on biological attractiveness factors...
April 25, 2024: Aesthetic Surgery Journal
https://read.qxmd.com/read/38662709/self-esteem-and-body-image-satisfaction-in-women-with-pcos-in-the-middle-east-cross-sectional-social-media-study
#12
JOURNAL ARTICLE
Zainab Alkheyr, Mariam Murad, Priya Das, Khaled Aljenaee, Charlotte Kamel, Sulaiman Ali Hajji, John Flood, Stephen L Atkin, Khawla F Ali
BACKGROUND: Polycystic ovary syndrome (PCOS) is the most common endocrine disorder in women of childbearing age, associated with increased incidence of emotional disorders, anxiety and depression. OBJECTIVE: The aim was of this study was to investigate whether those women reporting PCOS differed to women without PCOS in measures of psychological well-being including body-image satisfaction and self-esteem across a Middle Eastern population. MATERIALS AND METHODS: An online survey link of 21 questions was shared and distributed across social media platforms (Instagram and WhatsApp)...
2024: PloS One
https://read.qxmd.com/read/38654306/the-absorption-addiction-model-of-celebrity-worship-in-search-of-a-broader-theoretical-foundation
#13
JOURNAL ARTICLE
Mara S Aruguete, Frederick Grieve, Ágnes Zsila, Rita Horváth, Zsolt Demetrovics, Lynn E McCutcheon
BACKGROUND: A large body of evidence suggests that some people have a strong, obsessive attachment to a favorite celebrity. The absorption-addiction model attempts to account for this extreme attachment, sometimes labeled "celebrity worship." According to the model, a small portion of celebrity admirers ("celebrity worshipers") become absorbed in the personal lives of celebrities to compensate for perceived personal or social deficiencies. The purpose of this study is to examine how the absorption-addiction model relates to broader psychological theories that include non-celebrity contexts...
April 23, 2024: BMC Psychology
https://read.qxmd.com/read/38652231/diagnostic-and-therapeutic-use-of-oral-micronized-progesterone-in-endocrinology
#14
REVIEW
Eleni Memi, Polina Pavli, Papagianni Maria, Nikolaos Vrachnis, George Mastorakos
Progesterone is a natural steroid hormone, while progestins are synthetic molecules. In the female reproductive system, progesterone contributes to the control of luteinizing hormone and follicle-stimulating hormone secretion and their pulsatility, via its receptors on the kisspeptin, neurokinin B, and dynorphin neurons in the hypothalamus. Progesterone together with estradiol controls the cyclic changes of proliferation and decidualization of the endometrium; exerts anti-mitogenic actions on endometrial epithelial cells; regulates normal menstrual bleeding; contributes to fertilization and pregnancy maintenance; participates in the onset of labor...
April 23, 2024: Reviews in Endocrine & Metabolic Disorders
https://read.qxmd.com/read/38648092/stimulating-preconception-care-uptake-by-women-with-a-vulnerable-health-status-through-a-mobile-health-app-pregnant-faster-pilot-feasibility-study
#15
JOURNAL ARTICLE
Sharissa M Smith, Babette Bais, Hafez Ismaili M'hamdi, Maartje Hn Schermer, Régine Pm Steegers-Theunissen
BACKGROUND: A low socioeconomic status is associated with a vulnerable health status (VHS) through the accumulation of health-related risk factors, such as poor lifestyle behaviors (eg, inadequate nutrition, chronic stress, and impaired health literacy). For pregnant women, a VHS translates into a high incidence of adverse pregnancy outcomes and therefore pregnancy-related inequity. We hypothesize that stimulating adequate pregnancy preparation, targeting lifestyle behaviors and preconception care (PCC) uptake, can reduce these inequities and improve the pregnancy outcomes of women with a VHS...
April 22, 2024: JMIR Human Factors
https://read.qxmd.com/read/38643945/inhibition-of-yap-taz-pathway-contributes-to-the-cytotoxicity-of-silibinin-in-mcf-7-and-mda-mb-231-human-breast-cancer-cells
#16
JOURNAL ARTICLE
Jianing Fu, Weiwei Liu, Siyu Liu, Ruxiao Zhao, Toshihiko Hayashi, Haina Zhao, Yinlanqi Xiang, Kazunori Mizuno, Shunji Hattori, Hitomi Fujisaki, Takashi Ikejima
Breast cancer is one of the most common cancers threatening women's health. Our previous study found that silibinin induced the death of MCF-7 and MDA-MB-231 human breast cancer cells. We noticed that silibinin-induced cell damage was accompanied by morphological changes, including the increased cell aspect ratio (cell length/width) and decreased cell area. Besides, the cytoskeleton is also destroyed in cells treated with silibinin. YAP/TAZ, a mechanical signal sensor interacted with extracellular pressure, cell adhesion area and cytoskeleton, is also closely associated with cell survival, proliferation and migration...
April 19, 2024: Cellular Signalling
https://read.qxmd.com/read/38640590/longitudinal-changes-in-sexual-desire-and-attraction-among-women-who-started-using-the-natural-cycles-app
#17
JOURNAL ARTICLE
Jeffrey Gassen, Summer Mengelkoch, Divya Shanmugam, Jack T Pearson, Agathe van Lamsweerde, Eleonora Benhar, Sarah E Hill
Many women experience sexual side effects, such as decreased libido, when taking hormonal contraceptives (HCs). However, little is known about the extent to which libido recovers after discontinuing HCs, nor about the timeframe in which recovery is expected to occur. Given that HCs suppress the activities of multiple endogenous hormones that regulate both the ovulatory cycle and women's sexual function, resumption of cycles should predict libido recovery. Here, using a combination of repeated and retrospective measures, we examined changes in sexual desire and partner attraction (among partnered women) across a three-month period in a sample of Natural Cycles users (Survey 1: n = 1596; Survey 2: n = 550) who recently discontinued HCs...
April 18, 2024: Hormones and Behavior
https://read.qxmd.com/read/38632710/knowledge-transfer-and-networking-upon-implementation-of-a-transdisciplinary-digital-health-curriculum-in-a-unique-digital-health-training-culture-prospective-analysis
#18
JOURNAL ARTICLE
Juliane Kröplin, Leonie Maier, Jan-Hendrik Lenz, Bernd Romeike
BACKGROUND: Digital health has been taught at medical faculties for a few years. However, in general, the teaching of digital competencies in medical education and training is still underrepresented. OBJECTIVE: This study aims to analyze the objective acquisition of digital competencies through the implementation of a transdisciplinary digital health curriculum as a compulsory elective subject at a German university. The main subject areas of digital leadership and management, digital learning and didactics, digital communication, robotics, and generative artificial intelligence were developed and taught in a transdisciplinary manner over a period of 1 semester...
April 15, 2024: JMIR Medical Education
https://read.qxmd.com/read/38626437/women-s-representation-as-principal-investigators-among-pediatric-orthopaedic-clinical-trials-an-analysis-of-clinicaltrials-gov
#19
JOURNAL ARTICLE
Amir H Karimi, Robert J Burkhart, Monish Lavu, Aakash K Shah, R Justin Mistovich
INTRODUCTION: Despite recent efforts to increase the participation of women in orthopaedic surgery, there remains a gender gap, particularly when compared with other medical specialties. Acting as a principal investigator (PI) in a clinical trial can give physicians notable exposure and national recognition, which can improve their chances of promotion and tenure. This study aims to assess the proportion of women serving as PIs in pediatric orthopaedic clinical trials, examine associated trial characteristics, and explore geographic distribution...
April 10, 2024: Journal of the American Academy of Orthopaedic Surgeons
https://read.qxmd.com/read/38624136/the-role-of-gender-and-sexuality-in-the-experience-internalization-and-mental-health-correlates-of-sexual-victimization-stigma
#20
JOURNAL ARTICLE
Hilary Faithfull Farmer, Jamie E M Byrne, Alexander J Mussap
The stigma associated with sexual victimization (SV) can add to the psychological burden on survivors. We compared experiences of SV and SV stigma by survivor gender and sexuality and evaluated the relevance of public and internalized sources of this stigma to their psychological functioning. An online survey containing measures of SV type (sexual harassment and assault), public SV stigma, internalized SV stigma (self-blame, self-shame, anticipated-shame), and psychological functioning (depression, anxiety, stress, and post-traumatic stress disorder [PTSD] symptomatology) was completed by 877 women and 211 men aged 18 to 66 years ( M  = 30...
April 16, 2024: Journal of Interpersonal Violence
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