Min-Ling Liu, Xiao-Min Liang, Ming-Yu Jin, Hui-Wei Huang, Lin Luo, Hong Wang, Xing Shen, Zhen-Lin Xu
Food-borne biotoxins from microbes, plants, or animals contaminate unclean, spoiled, and rotten foods, posing significant health risks. Neutralizing such toxins is vital for human health, especially after food poisoning. Nanobodies (Nbs), a type of single-domain antibodies derived from the genetic cloning of a variable domain of heavy chain antibodies (VHHs) in camels, offer unique advantages in toxin neutralization. Their small size, high stability, and precise binding enable effective neutralization. The use of Nbs in neutralizing food-borne biotoxins offers numerous benefits, and their genetic malleability allows tailored optimization for diverse toxins...
May 5, 2024: Journal of Agricultural and Food Chemistry