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https://www.readbyqxmd.com/read/28636053/evidence-of-bad-recycling-practices-bfrs-in-children-s-toys-and-food-contact-articles
#1
A Guzzonato, F Puype, S J Harrad
Brominated flame retardants (BFRs) have been used intentionally in a wide range of plastics, but are now found in an even wider range of such materials (including children's toys and food contact articles) as a result of recycling practices that mix BFR-containing waste plastics with "virgin" materials. In this study Br was quantified in toy and food contact samples on the assumption that its concentration can be used as a metric for BFR contamination. Subsequently, compound specific determination of BFRs was performed to evaluate the validity of the aforementioned assumption, crucial to render rapid, inexpensive, in situ Br determination in non-laboratory environments (such as waste handling facilities) a viable option for sorting wastes according to their BFR content...
June 21, 2017: Environmental Science. Processes & Impacts
https://www.readbyqxmd.com/read/28631127/toxicity-of-cypermethrin-on-the-embryo-and-larvae-of-gangetic-mystus-mystus-cavasius
#2
Md Haider Ali, Kizar Ahmed Sumon, Marin Sultana, Harunur Rashid
The objective of the present study was to elucidate the effects of cypermethrin on the embryo and the larvae of Gangetic mystus, Mystus cavasius. Therefore, fertilized eggs (n = 100) and 1-day-old larvae (n = 100) were exposed to six different concentrations of cypermethrin (0, 2, 4, 8, 16 and 32 μg L(-1)) in each of the 18 plastic bowls. Each of the treatment and control was maintained in three replicates. The LC10 and LC50 values for Gangetic mystus embryos and larvae were calculated using probit analysis...
June 19, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28628971/occurrence-of-phthalate-diesters-in-indoor-air-from-several-northern-cities-in-vietnam-and-its-implication-for-human-exposure
#3
Tri Manh Tran, Hanh Thi Le, Tu Binh Minh, Kurunthachalam Kannan
Phthalates are used as plasticizers to impart flexibility of plastics. Because of their toxicity, human exposure to phthalates is a concern. Little is known on the occurrence of and inhalation exposure to phthalates in indoor air. In this study, ten phthalates were measured in 97 indoor air samples collected from Northern Vietnam during September 2016 to January 2017. The mean concentrations of total phthalates (i.e., sum of ten phthalates) in particulate and gas phases ranged from 95.2 to 13,100μgg(-1) and from 57...
June 13, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28625925/vanadium-exposure-induced-striatal-learning-and-memory-alterations-in-rats
#4
Liping Sun, Keyue Wang, Yan Li, Qiyuan Fan, Wei Zheng, Hong Li
Occupational and environmental exposure to vanadium has been associated with toxicities in reproductive, respiratory, and cardiovascular systems. The knowledge on whether and how vanadium exposure caused neurobehavioral changes remains incomplete. This study was designed to investigate the changes in learning and memory following drinking water exposure to vanadium, and to conduct the preliminary study on underlying mechanisms. Male Sprague-Dawley rats were exposed to vanadium dissolved in drinking water at the concentration of 0...
June 15, 2017: Neurotoxicology
https://www.readbyqxmd.com/read/28620860/currently-used-organophosphate-and-brominated-flame-retardants-in-the-environment-of-china-and-other-developing-countries-2000-2016
#5
Nadeem Ali, Khurram Shahzad, Muhammad Imtiaz Rashid, Heqing Shen, Iqbal Mohammad Ibrahim Ismail, Syed Ali Musstjab Akber Shah Eqani
This review summarizes the environmental occurrence of new brominated flame retardants (NBFRs) and organophosphate compounds (OPs) in the environment of developing countries since 2000. The ban on the production and use of commercial formulations of polybrominated diphenyl ethers (PBDEs) have paved the way for the high use of NBFRs and OPs in consumer products to fulfill the fire safety regulations. Recent studies have shown that the ever increasing production volumes and extensive use of these chemicals as additive FRs and plasticizers have resulted into their ubiquitous occurrence in all environmental compartments...
June 16, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28618366/eu-3-functionalized-sc-mofs-turn-on-fluorescent-switch-for-ppb-level-biomarker-of-plastic-pollutant-polystyrene-in-serum-and-urine-and-on-site-detection-by-smartphone
#6
Xiao Lian, Tifang Miao, Xiaoyu Xu, Chi Zhang, Bing Yan
The harm of plastic pollutants for human and environment is being paid more and more attention. Polystyrene (PS) and styrene are toxic compounds used in large quantities in the production of fiberglass reinforced polyesters. In this work, a simple method was designed for independent detecting polystyrene and styrene biomarker (phenylglyoxylic acid, PGA) in serum and urine. We prepared Eu3+ functionalized Sc-based metal-organic frameworks as turn-on fluorescent switch for PGA. The distinct enhanced luminescence is observed from the Eu@MOFs with addition of PGA...
June 10, 2017: Biosensors & Bioelectronics
https://www.readbyqxmd.com/read/28615697/remodeling-of-the-cycling-transcriptome-of-the-oyster-crassostrea-gigas-by-the-harmful-algae-alexandrium-minutum
#7
Laura Payton, Mickael Perrigault, Claire Hoede, Jean-Charles Massabuau, Mohamedou Sow, Arnaud Huvet, Floriane Boullot, Caroline Fabioux, Hélène Hegaret, Damien Tran
As a marine organism, the oyster Crassostrea gigas inhabits a complex biotope governed by interactions between the moon and the sun cycles. We used next-generation sequencing to investigate temporal regulation of oysters under light/dark entrainment and the impact of harmful algal exposure. We found that ≈6% of the gills' transcriptome exhibits circadian expression, characterized by a nocturnal and bimodal pattern. Surprisingly, a higher number of ultradian transcripts were also detected under solely circadian entrainment...
June 14, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28607171/astrocyte-transforming-growth-factor-beta-1-protects-synapses-against-a%C3%AE-oligomers-in-alzheimer-s-disease-model
#8
Luan Pereira Diniz, Vanessa Tortelli, Isadora Matias, Juliana Morgado, Ana Paula Bérgamo Araujo, Helen M Melo, Gisele S Seixas da Silva, Soniza V Alves-Leon, Jorge M de Souza, Sergio T Ferreira, Fernanda G De Felice, Flávia Carvalho Alcantara Gomes
Alzheimer's disease (AD) is characterized by progressive cognitive decline, increasingly attributed to neuronal dysfunction induced by amyloid-β oligomers (AβOs). Although the impact of AβOs on neurons has been extensively studied, only recently have the possible effects of AβOs on astrocytes begun to be investigated. Given the key roles of astrocytes in synapse formation, plasticity and function, we sought to investigate the impact of AβOs on astrocytes, and to determine if this impact is related to the deleterious actions of AβOs on synapses...
June 12, 2017: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/28607072/adaptor-protein-mediates-dynamic-pump-assembly-for-bacterial-metal-efflux
#9
Ace George Santiago, Tai-Yen Chen, Lauren A Genova, Won Jung, Alayna M George Thompson, Megan M McEvoy, Peng Chen
Multicomponent efflux complexes constitute a primary mechanism for Gram-negative bacteria to expel toxic molecules for survival. As these complexes traverse the periplasm and link inner and outer membranes, it remains unclear how they operate efficiently without compromising periplasmic plasticity. Combining single-molecule superresolution imaging and genetic engineering, we study in living Escherichia coli cells the tripartite efflux complex CusCBA of the resistance-nodulation-division family that is essential for bacterial resistance to drugs and toxic metals...
June 12, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/28602253/understanding-interactive-inducible-defenses-of-daphnia-and-its-phytoplankton-prey
#10
Siddiq Akbar, Jingjing Du, Hong Lin, Xiangshi Kong, Shucun Sun, Xingjun Tian
Cyanobacterial and zooplankton inducible defenses are important but understudied process that regulate the trophic interactions of freshwater ecosystem. Daphnia due to its large size is considered an important zooplankton with the high potential to control cyanobacterial blooms. It has been shown that Daphnia through maternal induction transfer tolerance to their next generation against Microcystis toxicity. Maternal induction has been investigated in different Daphnia species without considering phenotypic plasticity of prey...
June 2017: Harmful Algae
https://www.readbyqxmd.com/read/28601518/biochemical-responses-and-ultrastructural-changes-in-ethylene-insensitive-mutants-of-arabidopsis-thialiana-subjected-to-bisphenol-a-exposure
#11
Imran Ali, Mehmood Jan, Abdul Wakeel, Azizullah Azizullah, Bohan Liu, Faisal Islam, Abid Ali, M K Daud, Yihua Liu, Yinbo Gan
Bisphenol A (BPA), an important raw material in plastic industry, has become a serious environmental contaminant due to its wide spread use in different products and increasing release into the environment. BPA is known to cause adverse effects in living organisms including plants. Several studies reported that BPA affects growth and development in plants, mainly through oxidative stress. Plants are known to generally cope with stress mainly through hormonal regulation and adaptation, but little is known about the role of plant hormones in plants under BPA stress...
June 8, 2017: Ecotoxicology and Environmental Safety
https://www.readbyqxmd.com/read/28594093/size-and-shape-dependent-effects-of-microplastic-particles-on-adult-daggerblade-grass-shrimp-palaemonetes-pugio
#12
Austin D Gray, John E Weinstein
The incidence of microplastics in marine environments has been increasing over the past several decades. The objective of this study was to characterize the size and shape dependent effects of microplastic particles (spheres, fibers and fragments) on the adult daggerblade grass shrimp, Palaemonetes pugio. Grass shrimp were exposed to 11 sizes of plastic; spheres (30, 35, 59, 75, 83, 116, and 165 µm), fragments (34 and 93 µm), and fibers (34 and 93 µm) at a concentration of 20,00 particles/400 mL (= 50,000 particles/L) for three hours...
June 8, 2017: Environmental Toxicology and Chemistry
https://www.readbyqxmd.com/read/28592106/-progress-in-environmental-exposure-of-organophosphate-flame-retardants
#13
J J Ding, F X Yang
Organophosphate flame retardants (OPFRs), which have both great properties of flame retardation and plasticization, are currently widely used as additive flame retardants. Due to the restriction and phase-out of brominated flame retardants (BFRs), the market demand for OPFRs as excellent alternatives of BFRs has been rapid increasing. OPFRs can be slowly released into the environment during production and application. Some OPFRs might be persistent in the environment. As a result, OPFRs have been detected in various matrices in the environment and are expected to accumulate in human body through various pathways...
June 6, 2017: Zhonghua Yu Fang Yi Xue za Zhi [Chinese Journal of Preventive Medicine]
https://www.readbyqxmd.com/read/28578073/identification-of-endocrine-disrupting-chemicals-acting-on-human-aromatase
#14
Roberta Baravalle, Alberto Ciaramella, Francesca Baj, Giovanna Di Nardo, Gianfranco Gilardi
Human aromatase is the cytochrome P450 catalysing the conversion of androgens into estrogens playing a key role in the endocrine system. Due to this role, it is likely to be a target of the so-called endocrine disrupting chemicals, a series of compounds able to interfere with the hormone system with toxic effects. If on one side the toxicity of some compounds such as bisphenol A is well known, on the other side the toxic concentrations of such compounds as well as the effect of the many other molecules that are in contact with us in everyday life still need a deep investigation...
May 31, 2017: Biochimica et Biophysica Acta
https://www.readbyqxmd.com/read/28577099/toxic-effects-of-nanostructured-silicon-dioxide-on-multipotent-mesenchymal-stromal-cells
#15
A P Lykov, Yu A Lykova, O V Poveshchenko, N A Bondarenko, M A Surovtseva, N P Bgatova, V I Konenkov
We studied the effect of nanostructured silicon dioxide particles on functional activity and ultrastructure of rat multipotent mesenchymal stem cells. A dose-dependent decrease in cell adhesion to plastics and their proliferative potential, accumulation of apoptotic cells, a decrease in the electron density of cell cytoplasm due to swelling and degenerative changes of organelles, and intracellular accumulation of nanostructured of silicon dioxide particles were observed.
June 3, 2017: Bulletin of Experimental Biology and Medicine
https://www.readbyqxmd.com/read/28576411/postnatal-hyperoxia-or-dehp-exposure-leads-to-growth-restriction-and-delayed-lung-development-in-newborn-rats
#16
Zhong-Jie Liang, Qiu-Ping Wu, Bei-Tao Chen, Zhen-Lang Lin, Jing Lin, Shang-Qin Chen
BACKGROUND: Di-(2-ethylhexyl) phthalate (DEHP) is commonly used as a plasticizer in many medical devices. We previously showed that maternal DEHP exposure led to restricted growth and delayed lung maturation in newborn rats. As oxygen toxicity continues to be a major risk factor for bronchopulmonary dysplasia, the aim of this study was to examine the effect of hyperoxia, DEHP or DEHP combined with hyperoxia on the growth and lung maturation of newborn rats. METHODS: Newborn rats received DEHP injection, hyperoxia exposure or DEHP injection combined with hyperoxia exposure for one week or two weeks...
May 10, 2017: Pediatrics and Neonatology
https://www.readbyqxmd.com/read/28567415/neurodevelopmental-disorders-and-environmental-toxicants-epigenetics-as-an-underlying-mechanism
#17
REVIEW
Nguyen Quoc Vuong Tran, Kunio Miyake
The increasing prevalence of neurodevelopmental disorders, especially autism spectrum disorders (ASD) and attention deficit hyperactivity disorder (ADHD), calls for more research into the identification of etiologic and risk factors. The Developmental Origin of Health and Disease (DOHaD) hypothesizes that the environment during fetal and childhood development affects the risk for many chronic diseases in later stages of life, including neurodevelopmental disorders. Epigenetics, a term describing mechanisms that cause changes in the chromosome state without affecting DNA sequences, is suggested to be the underlying mechanism, according to the DOHaD hypothesis...
2017: International Journal of Genomics
https://www.readbyqxmd.com/read/28545000/occurrence-and-effects-of-plastic-additives-on-marine-environments-and-organisms-a-review
#18
REVIEW
Ludovic Hermabessiere, Alexandre Dehaut, Ika Paul-Pont, Camille Lacroix, Ronan Jezequel, Philippe Soudant, Guillaume Duflos
Plastics debris, especially microplastics, have been found worldwide in all marine compartments. Much research has been carried out on adsorbed pollutants on plastic pieces and hydrophobic organic compounds (HOC) associated with microplastics. However, only a few studies have focused on plastic additives. These chemicals are incorporated into plastics from which they can leach out as most of them are not chemically bound. As a consequence of plastic accumulation and fragmentation in oceans, plastic additives could represent an increasing ecotoxicological risk for marine organisms...
May 16, 2017: Chemosphere
https://www.readbyqxmd.com/read/28536799/stress-induced-transcriptional-changes-and-dna-damage-associated-with-bis-2-ethylhexyl-adipate-exposure-in-zebrafish-danio-rerio-larvae
#19
Halis Boran, Serap Terzi
The present study evaluates potential toxic effects of bis(2-ethylhexyl) adipate (DEHA) plasticizer to larval (72 h post fertilization) zebrafish (Danio rerio) by analyzing changes in expression levels of stress-related genes (p53, rad51 and xrcc5) and assessing possible DNA damage of DEHA in larvae. The lethal concentration for 50% mortality (LC50) in larval zebrafish exposed for 96 h to 0-200 mg L(-1) DEHA was 89.9 ± 8.03 mg L(-1). A concentration-dependent increase in DNA strand breaks was detected in cells from larvae exposed for 96 h to DEHA...
May 24, 2017: Bulletin of Environmental Contamination and Toxicology
https://www.readbyqxmd.com/read/28531345/plastic-and-human-health-a-micro-issue
#20
Stephanie L Wright, Frank J Kelly
Microplastics are a pollutant of environmental concern. Their presence in food destined for human consumption and in air samples has been reported. Thus, microplastic exposure via diet or inhalation could occur, the human health effects of which are unknown. The current review article draws upon cross-disciplinary scientific literature to discuss and evaluate the potential human health impacts of microplastics and outlines urgent areas for future research. Key literature up to September 2016 relating to accumulation, particle toxicity, and chemical and microbial contaminants was critically examined...
June 7, 2017: Environmental Science & Technology
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