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Depression and work impairment

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https://www.readbyqxmd.com/read/29234305/functional-components-of-cognitive-impairment-in-multiple-sclerosis-a-cross-sectional-investigation
#1
Jordi A Matias-Guiu, Ana Cortés-Martínez, María Valles-Salgado, Celia Oreja-Guevara, Vanesa Pytel, Paloma Montero, Teresa Moreno-Ramos, Jorge Matias-Guiu
Background: Cognitive impairment is frequent and disabling in multiple sclerosis (MS). Changes in information processing speed constitute the most important cognitive deficit in MS. However, given the clinical and topographical variability of the disease, cognitive impairment may vary greatly and appear in other forms in addition to slower information processing speed. Our aim was to determine the frequency of cognitive impairment, the principal cognitive domains, and components involved in MS and to identify factors associated with presence of cognitive impairment in these patients in a large series of patients...
2017: Frontiers in Neurology
https://www.readbyqxmd.com/read/29228516/refining-prediction-in-treatment-resistant-depression-results-of-machine-learning-analyses-in-the-trd-iii-sample
#2
Alexander Kautzky, Markus Dold, Lucie Bartova, Marie Spies, Thomas Vanicek, Daniel Souery, Stuart Montgomery, Julien Mendlewicz, Joseph Zohar, Chiara Fabbri, Alessandro Serretti, Rupert Lanzenberger, Siegfried Kasper
OBJECTIVE: The study objective was to generate a prediction model for treatment-resistant depression (TRD) using machine learning featuring a large set of 47 clinical and sociodemographic predictors of treatment outcome. METHOD: 552 Patients diagnosed with major depressive disorder (MDD) according to DSM-IV criteria were enrolled between 2011 and 2016. TRD was defined as failure to reach response to antidepressant treatment, characterized by a Montgomery-Asberg Depression Rating Scale (MADRS) score below 22 after at least 2 antidepressant trials of adequate length and dosage were administered...
December 5, 2017: Journal of Clinical Psychiatry
https://www.readbyqxmd.com/read/29228293/providing-mental-health-care-for-the-complex-older-veteran-implications-for-social-work-practice
#3
Gayle Clark, Susan Rouse, Heather Spangler, Jennifer Moye
Mental health conditions are underdiagnosed and undertreated in older veterans, as with all older adults. Social workers bring an important perspective to the interdisciplinary team for the care of older veterans with mental health conditions. In this study authors assessed 50 older veterans referred for mental health treatment (mean age = 74.52 years, SD = 6.48) with standardized measures of depression, posttraumatic stress disorder (PTSD), and cognitive impairment. At initial assessment, 24 percent had moderate depression, 30 percent had PTSD, and 62 percent (n = 31) had (mostly mild) cognitive impairment based on cut scores...
December 8, 2017: Health & Social Work
https://www.readbyqxmd.com/read/29228200/ect-has-greater-efficacy-than-fluoxetine-in-alleviating-the-burden-of-illness-for-patients-with-major-depressive-disorder-a-taiwanese-pooled-analysis
#4
Ching-Hua Lin, Chun-Jen Huang, Cheng-Chung Chen
Background: The burden of major depressive disorder (MDD) includes suffering due to symptom severity, functional impairment, and quality of life (QOL) deficits. The aim of this study was to compare the differences between ECT and pharmacotherapy in reducing such burdens. Methods: This was a pooled analysis study including two open-label trials for MDD inpatients receiving either standard bitemporal and modified ECT with a maximum of 12 sessions, or 20 mg/d of fluoxetine for 6 weeks...
December 8, 2017: International Journal of Neuropsychopharmacology
https://www.readbyqxmd.com/read/29224581/executive-function-and-other-cognitive-deficits-are-distal-risk-factors-of-generalized-anxiety-disorder-9-years-later
#5
Nur Hani Zainal, Michelle G Newman
OBJECTIVE: The cognitive model (Hirsch & Mathews, 2012) and attentional control theory (Eysenck & Derakshan, 2011) postulate that compromised executive function (EF) and other cognitive constructs are negatively linked to increased excessive and uncontrollable worry, the core symptom of generalized anxiety disorder (GAD). However, the prospective link between neuropsychological constructs and GAD are not well understood. METHODS: A nationally representative sample of 2605 community-dwelling adults whose average age was 55...
December 11, 2017: Psychological Medicine
https://www.readbyqxmd.com/read/29223069/neuropsychological-and-clinical-heterogeneity-of-cognitive-impairment-in-patients-with-multiple-system-atrophy
#6
Lorena Broseghini Barcelos, Flávia Saad, Carla Giacominelli, Roberta Arb Saba, Patrícia Maria de Carvalho Aguiar, Sonia Maria Azevedo Silva, Vanderci Borges, Paulo Henrique Ferreira Bertolucci, Henrique Ballalai Ferraz
OBJECTIVE: We evaluated neuropsychological tests to compare cognitive impairment between two types of multiple system atrophy: predominant parkinsonism (MSA-P) and predominant cerebellar ataxia (MSA-C). PATIENTS AND METHODS: This cross-sectional study included 14 patients diagnosed with MSA: four with MSA-C and ten with MSA-P. Presence of motor symptoms was determined by using the Unified Rating MSA Scale (URMSAS). Non-motor symptoms were evaluated by the Short Form Health Survey (SF-36), Scales for Outcomes in Parkinson's disease Autonomic (SCOPA-AUT), Hospital Anxiety and Depression Scale (HADS), and Beck Depression Inventory (BDI)...
October 31, 2017: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/29213522/memory-specificity-training-can-improve-working-and-prospective-memory-in-amnestic-mild-cognitive-impairment
#7
Golita Emsaki, Hamid Taher NeshatDoost, Mahgol Tavakoli, Majid Barekatain
Amnestic Mild Cognitive Impairment (MCI) is one of the cognitive profiles of aging. OBJECTIVE: In this study, Memory Specificity Training (MEST) was used as cognitive training in patients with amnestic MCI to understand the effectiveness of the intervention on memory dimensions. METHODS: Twenty patients that met the criteria for amnestic MCI were selected and randomly assigned to experimental (n=10) or control (n=10) groups. The experimental group received five sessions of training on memory specificity while the participants in the control group took part in two general placebo sessions...
July 2017: Dementia & Neuropsychologia
https://www.readbyqxmd.com/read/29213506/symptoms-of-depression-in-patients-with-mild-cognitive-impairment-in-parkinson-s-disease
#8
Ana Lara Soares Blum Malak, Luiz Felipe Vasconcellos, João Santos Pereira, Denise Vieira Greca, Manuela Cruz, Heloisa Veiga Dias Alves, Mariana Sptiz, Helenice Charchat-Fichman
Objective: To investigate the most frequent depressive symptoms and their association with cognition in Parkinson's disease (PD) patients with mild cognitive impairment (MCI). Methods: 48 patients with PD and 44 controls (CG), aged between 50 and 80 years and with at least 4 years of formal education, all with MCI and none diagnosed with depression, were assessed. Patients and controls were matched for age, education, and Mini-Mental State Examination (MMSE) score...
April 2017: Dementia & Neuropsychologia
https://www.readbyqxmd.com/read/29212489/health-care-utilization-of-patients-with-chronic-back-pain-before-and-after-rehabilitation
#9
Magdalena Görge, Jeanette Ziehm, Erik Farin
BACKGROUND: Patients with chronic back pain show an increased use of health-care services leading to high direct costs. Multidisciplinary rehabilitation reduces pain intensity, depression, disability and work inability. The study aims to investigate whether health-care utilization in patients with chronic back pain is lower after rehabilitation than before rehabilitation and if, in addition to sociodemographic, medical and psychological characteristics, changes in these characteristics immediately after rehabilitation can predict health-care utilization...
December 6, 2017: BMC Health Services Research
https://www.readbyqxmd.com/read/29209393/relationship-between-problematic-internet-use-and-post-traumatic-stress-disorder-symptoms-among-students-following-the-sewol-ferry-disaster-in-south-korea
#10
Ju-Yeon Lee, Sung-Wan Kim, Hee-Ju Kang, Seon-Young Kim, Kyung-Yeol Bae, Jae-Min Kim, Il-Seon Shin, Jin-Sang Yoon
We investigated the association between problematic internet use (PIU) and post-traumatic stress disorder (PTSD) symptoms in children and adolescents in South Korea. A cross-sectional survey was administered to community students who attended primary, secondary, and high schools in the Jindo area 1-2.5 months after the Sewol ferry disaster. Of the 1,744 respondents, 392 students who were exposed to the disaster, witnessing the rescue work directly, were evaluated. PTSD symptoms were measured using the University of California Los Angeles Post-traumatic Stress Disorder Reaction Index (UCLA PTSD-RI)...
November 2017: Psychiatry Investigation
https://www.readbyqxmd.com/read/29209272/a-european-perspective-on-auditory-processing-disorder-current-knowledge-and-future-research-focus
#11
Vasiliki Vivian Iliadou, Martin Ptok, Helen Grech, Ellen Raben Pedersen, André Brechmann, Naïma Deggouj, Christiane Kiese-Himmel, Mariola Śliwińska-Kowalska, Andreas Nickisch, Laurent Demanez, Evelyne Veuillet, Hung Thai-Van, Tony Sirimanna, Marina Callimachou, Rosamaria Santarelli, Sandra Kuske, Jose Barajas, Mladen Hedjever, Ozlem Konukseven, Dorothy Veraguth, Tone Stokkereit Mattsson, Jorge Humberto Martins, Doris-Eva Bamiou
Current notions of "hearing impairment," as reflected in clinical audiological practice, do not acknowledge the needs of individuals who have normal hearing pure tone sensitivity but who experience auditory processing difficulties in everyday life that are indexed by reduced performance in other more sophisticated audiometric tests such as speech audiometry in noise or complex non-speech sound perception. This disorder, defined as "Auditory Processing Disorder" (APD) or "Central Auditory Processing Disorder" is classified in the current tenth version of the International Classification of diseases as H93...
2017: Frontiers in Neurology
https://www.readbyqxmd.com/read/29196982/a-brief-instrument-to-assess-both-burnout-and-professional-fulfillment-in-physicians-reliability-and-validity-including-correlation-with-self-reported-medical-errors-in-a-sample-of-resident-and-practicing-physicians
#12
Mickey Trockel, Bryan Bohman, Emi Lesure, Maryam S Hamidi, Dana Welle, Laura Roberts, Tait Shanafelt
OBJECTIVE: The objective of this study was to evaluate the performance of the Professional Fulfillment Index (PFI), a 16-item instrument to assess physicians' professional fulfillment and burnout, designed for sensitivity to change attributable to interventions or other factors affecting physician well-being. METHODS: A sample of 250 physicians completed the PFI, a measure of self-reported medical errors, and previously validated measures including the Maslach Burnout Inventory (MBI), a one-item burnout measure, the World Health Organization's abbreviated quality of life assessment (WHOQOL-BREF), and PROMIS short-form depression, anxiety, and sleep-related impairment scales...
December 1, 2017: Academic Psychiatry
https://www.readbyqxmd.com/read/29196216/a-third-copy-of-the-down-syndrome-cell-adhesion-molecule-dscam-causes-synaptic-and-locomotor-dysfunction-in-drosophila
#13
Simon A Lowe, James J L Hodge, Maria M Usowicz
Down syndrome (DS) is caused by triplication of chromosome 21 (HSA21). It is characterised by intellectual disability and impaired motor coordination that arise from changes in brain volume, structure and function. However, the contribution of each HSA21 gene to these various phenotypes and to the causal alterations in neuronal and synaptic structure and function are largely unknown. Here we have investigated the effect of overexpression of the HSA21 gene DSCAM (Down syndrome cell adhesion molecule), on glutamatergic synaptic transmission and motor coordination, using Drosophila expressing three copies of Dscam1...
November 28, 2017: Neurobiology of Disease
https://www.readbyqxmd.com/read/29195773/cognitive-deficits-in-bipolar-disorders-implications-for-emotion
#14
REVIEW
Isabela M M Lima, Andrew D Peckham, Sheri L Johnson
Prominent cognitive deficits have been documented in bipolar disorder, and multiple studies suggest that these deficits can be observed among non-affected first-degree relatives of those with bipolar disorder. Although there is variability in the degree of cognitive deficits, these deficits are robustly relevant for functional outcomes. A separate literature documents clear difficulties in emotionality, emotion regulation, and emotion-relevant impulsivity within bipolar disorder, and demonstrates that these emotion-relevant variables are also central to outcome...
November 21, 2017: Clinical Psychology Review
https://www.readbyqxmd.com/read/29195684/mice-lacking-interleukin-18-gene-display-behavioral-changes-in-animal-models-of-psychiatric-disorders-possible-involvement-of-immunological-mechanisms
#15
S F Lisboa, A C Issy, C Biojone, K Montezuma, V Fattori, E A Del-Bel, F S Guimarães, F Q Cunha, W A Verri, S R L Joca
Preclinical and clinical evidence suggests pro-inflammatory cytokines might play an important role in the neurobiology of schizophrenia and stress-related psychiatric disorders. Interleukin-18 (IL-18) is a member of the IL-1 family of cytokines and it is widely expressed in brain regions involved in emotional regulation. Since IL-18 involvement in the neurobiology of mental illnesses, including schizophrenia, remains unknown, this work aimed at investigating the behavior of IL-18 null mice (KO) in different preclinical models: 1...
November 10, 2017: Journal of Neuroimmunology
https://www.readbyqxmd.com/read/29193182/cognitive-impairment-and-quality-of-life-in-patients-with-myotonic-dystrophy-type-1
#16
Haruo Fujino, Honoka Shingaki, Shugo Suwazono, Yukihiko Ueda, Chizu Wada, Takahiro Nakayama, Masanori P Takahashi, Osamu Imura, Tsuyoshi Matsumura
INTRODUCTION: We aimed to clarify whether specific cognitive abilities are impaired in patients with myotonic dystrophy type 1 (DM1), as well as to investigate the relationships among quality of life (QoL), cognitive function, and psychological factors. METHODS: Sixty patients with DM1 were evaluated on cognitive functioning (abstract reasoning, attention/working memory, executive function, processing speed, and visuo-constructive ability), apathy, depression, excessive daytime sleepiness, fatigue, and QoL...
November 28, 2017: Muscle & Nerve
https://www.readbyqxmd.com/read/29189296/long-term-outcome-after-the-acute-respiratory-distress-syndrome-different-from-general-critical-illness
#17
Thomas Bein, Steffen Weber-Carstens, Christian Apfelbacher
PURPOSE OF REVIEW: To review the current research data on long-term outcome and health-related quality of life in survivors of the acute respiratory distress syndrome (ARDS) and to compare these findings with those from non-ARDS patients surviving critical illness. RECENT FINDINGS: Between 6 months and 2 years after discharge from ICU, survivors of ARDS present with substantial impairments of the levels of body function (muscle strength, walking capacity and/or physical activity (physical SF-36 score)...
December 1, 2017: Current Opinion in Critical Care
https://www.readbyqxmd.com/read/29183537/continuing-trauma-the-unmet-needs-of-trauma-patients-in-the-postacute-care-setting
#18
Samir M Fakhry, Pamela L Ferguson, Jama L Olsen, Jennifer J Haughney, Heidi S Resnick, Kenneth J Ruggiero
Trauma care has traditionally focused on prehospital and hospital settings, yet many injured patients report emotional distress in the postacute care setting, which is known to impair recovery. The objective of this study was to assess postdischarge emotional recovery and communication preferences. An observational cohort of 100 adult patients from our Level 1 Trauma Center was surveyed one to two months postdischarge. Among those employed preinjury, 44 per cent had not returned to work. Nearly half screened positive for emotional issues (posttraumatic stress disorder, depression, and/or psychological distress); of these, only 35 per cent considered getting professional help and only 10 per cent received help...
November 1, 2017: American Surgeon
https://www.readbyqxmd.com/read/29165968/restless-legs-syndrome-and-sleep-quality-in-patients-on-hemodialysis
#19
Özlem Örsal, Alaettin Ünsal, Güler Balcı-Alparslan, Pınar Duru
Restless legs syndrome (RLS) is a common health problem in patients on hemodialysis. This descriptive study was carried out with patients from a hemodialysis unit in the province of Eskişehir, Turkey. Of the 317 patients in the unit, 244 (77.0%) comprised the study group. RLS was assessed by diagnostic criteria defined by the International RLS Working Group, sleep quality by the Pittsburgh Sleep Quality Index, and depression by the Beck Depression Inventory. RLS was found in 15.6% of patients and was associated with depression and sleep quality...
March 2017: Nephrology Nursing Journal: Journal of the American Nephrology Nurses' Association
https://www.readbyqxmd.com/read/29162085/association-of-lower-urinary-tract-symptoms-and-oab-severity-with-quality-of-life-and-mental-health-in-china-taiwan-and-south-korea-results-from-a-cross-sectional-population-based-study
#20
Kyu-Sung Lee, Tag Keun Yoo, Limin Liao, Jianye Wang, Yao-Chi Chuang, Shih-Ping Liu, Romeo Chu, Budiwan Sumarsono
BACKGROUND: Lower urinary tract symptoms (LUTS) and overactive bladder (OAB) symptoms have a substantial effect on quality of life (QoL). We report QoL and mental health results from a LUTS prevalence study in three Asian countries. METHODS: A cross-sectional, population-representative, internet-based study among individuals aged ≥40 years in China, Taiwan and South Korea. Instruments included: Overactive Bladder Symptom Score (OABSS); International Prostate Symptom Score (IPSS); other International Continence Society (ICS) symptom questions; health-related QoL 12-item short-form (HRQoL-SF12v2); Work Limitations Questionnaire (WLQ); Hospital Anxiety and Depression Scale (HADS)...
November 21, 2017: BMC Urology
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